Academic literature on the topic 'Interaction with biomolecule'

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Journal articles on the topic "Interaction with biomolecule"

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Zhou, Min, Weiping Li, Jian Li, et al. "Phase-separated condensate-aided enrichment of biomolecular interactions for high-throughput drug screening in test tubes." Journal of Biological Chemistry 295, no. 33 (2020): 11420–34. http://dx.doi.org/10.1074/jbc.ra120.012981.

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Modification-dependent and -independent biomolecular interactions, including protein–protein, protein–DNA/RNA, protein–sugar, and protein–lipid interactions, play crucial roles in all cellular processes. Dysregulation of these biomolecular interactions or malfunction of the associated enzymes results in various diseases; therefore, these interactions and enzymes are attractive targets for therapies. High-throughput screening can greatly facilitate the discovery of drugs for these targets. Here, we describe a biomolecular interaction detection method, called phase-separated condensate-aided enr
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Pronkin, Pavel G., and Alexander S. Tatikolov. "Photonics of Trimethine Cyanine Dyes as Probes for Biomolecules." Molecules 27, no. 19 (2022): 6367. http://dx.doi.org/10.3390/molecules27196367.

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Cyanine dyes are widely used as fluorescent probes in biophysics and medical biochemistry due to their unique photophysical and photochemical properties (their photonics). This review is focused on a subclass of the most widespread and studied cyanine dyes—trimethine cyanines, which can serve as potential probes for biomolecules. The works devoted to the study of the noncovalent interaction of trimethine cyanine dyes with biomolecules and changing the properties of these dyes upon the interaction are reviewed. In addition to the spectral-fluorescent properties, elementary photochemical propert
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Ekambaram, Rajasekaran, and Indupriya Rajasekaran. "Nanone interactions in antibody of living systems." Modern Health Science 4, no. 2 (2021): p1. http://dx.doi.org/10.30560/mhs.v4n2p1.

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One of the facts about how nanoparticle assemble and act is revealed using carbon value in biomolecule of living system here. This is how the biomolecules interact to bring about a micro or even macro level interaction in system of interest. This study shows micro level understanding can be better utilized from carbon analysis at nano level. I plan to extend this phenomena of change from nano to micro for building large scale applications in human nature. Applications include corrections in both at sequence and structure level for permanent recovery of defective one, adding flavor to the exist
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Zeindlhofer, Veronika, and Christian Schröder. "Computational solvation analysis of biomolecules in aqueous ionic liquid mixtures." Biophysical Reviews 10, no. 3 (2018): 825–40. http://dx.doi.org/10.1007/s12551-018-0416-5.

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Abstract Based on their tunable properties, ionic liquids attracted significant interest to replace conventional, organic solvents in biomolecular applications. Following a Gartner cycle, the expectations on this new class of solvents dropped after the initial hype due to the high viscosity, hydrolysis, and toxicity problems as well as their high cost. Since not all possible combinations of cations and anions can be tested experimentally, fundamental knowledge on the interaction of the ionic liquid ions with water and with biomolecules is mandatory to optimize the solvation behavior, the biode
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Chen, Jiajie, Youjun Zeng, Jie Zhou, et al. "Optothermophoretic flipping method for biomolecule interaction enhancement." Biosensors and Bioelectronics 204 (May 2022): 114084. http://dx.doi.org/10.1016/j.bios.2022.114084.

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Rowe, Rhianon K., and P. Shing Ho. "Relationships between hydrogen bonds and halogen bonds in biological systems." Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials 73, no. 2 (2017): 255–64. http://dx.doi.org/10.1107/s2052520617003109.

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The recent recognition that halogen bonding (XB) plays important roles in the recognition and assembly of biological molecules has led to new approaches in medicinal chemistry and biomolecular engineering. When designing XBs into strategies for rational drug design or into a biomolecule to affect its structure and function, we must consider the relationship between this interaction and the more ubiquitous hydrogen bond (HB). In this review, we explore these relationships by asking whether and how XBs can replace, compete against or behave independently of HBs in various biological systems. The
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Chaudhary, M., and K. Tyagi. "A REVIEW ON MOLECULAR DOCKING AND ITS APPLICATION." International Journal of Advanced Research 12, no. 03 (2024): 1141–53. http://dx.doi.org/10.21474/ijar01/18505.

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Molecular Docking is powerful computer strategy, critical in drug development, structural biology, and biomolecular interaction researchproviding a thorough grasp of its importance in modern scientific study. Molecular docking involves forecasting how a small molecule, often a potential medication, will interact with a target biomolecule like DNA or a protein. This process examines the spatial and energetic compatibility of the ligand with the active site of the receptor, assisting in the discovery of new drug candidates, refining existing compounds, and understanding the intricate interaction
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Fraikin, G. Ya. "Photosensitized reactions of oxidative damage to biomolecules: role in genotoxic and cytotoxic processes." Vestnik Moskovskogo universiteta. Seria 16. Biologia 79, no. 3, 2024 (2024): 167–83. https://doi.org/10.55959/msu0137-0952-16-79-3-1.

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Photosensitized oxidation reactions of biomolecules such as lipids, proteins, DNA initiate cytotoxic and genotoxic processes that are mediated by endogenous sensitizers under effect of ultraviolet radiation in the range A (UVA, 320–400 nm) on living systems. The photosensitization reactions are oxygen-dependent and depending upon primary mechanism are divided into type I and type II. Type I reactions involve electron transfer between photoexcited sensitizer and biomolecule with the formation of radical states. The interaction of radical cation of biomolecule with oxygen leads to the production
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Zhuravlova, Maryna, Nataliya Obernikhina, Stepan Pilyo, Maryna Kachaeva, Oleksiy Kachkovsky, and Volodymyr Brovarets. "In silico binding affinity studies of phenyl-substituted 1,3-oxazoles with protein molecules." Ukr. Bioorg. Acta 2020, Vol. 15, N1 15, no. 1 (2020): 12–19. http://dx.doi.org/10.15407/bioorganica2020.01.012.

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The new model approach of interaction between the pharmacophores with bio-molecules, fragment-to-fragment, is presented. It is a new step of the molecular modeling and takes correctly into consideration not only the spatial complementarity of the interacted molecules but also the contribution of the stacking π-π-electron interaction and hydrogen bonds. As an example, the correct analysis of the interaction of the biological active phenyl-substituted 1,3-oxazoles with protein fragments is performed. It was shown that the length and energy of the hydrogen bond uniquely depend on the chemical con
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Hatamipour, Mahdi, Thomas P. Johnston, and Amirhossein Sahebkar. "One Molecule, Many Targets and Numerous Effects: The Pleiotropy of Curcumin Lies in its Chemical Structure." Current Pharmaceutical Design 24, no. 19 (2018): 2129–36. http://dx.doi.org/10.2174/1381612824666180522111036.

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Curcumin quite possibly represents one of the most diverse therapeutic agents yet isolated from natural sources. Therapeutic benefits of this extraordinary natural compound have been demonstrated during treatment of a variety of diseases, including cancer, inflammatory processes, immunological disorders, Diabetes, and oxidative stress often associated with hyperlipidemia. Due to its unique molecular chemical structure and functional groups, curcumin may bind with and subsequently either inhibit or activate a variety of endogenous biomolecules, including enzymes, receptors, signaling molecules,
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Dissertations / Theses on the topic "Interaction with biomolecule"

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Kim, Jungseung. "Investigation of the Interactions between Biomolecules and Mesoporous Inorganic Materials in Biomolecule Immobilization for Bioseparation and Biocatalysis." University of Cincinnati / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1318861345.

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Ringeard, Jean-Marie. "Synthèse de matériaux hybrides par procédé sol-gel : optimisation des interactions biomolécules-matrice." Thesis, Cergy-Pontoise, 2013. http://www.theses.fr/2013CERG0684.

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Le contrôle de la qualité des ressources en eau nécessite des outils de détection en continu et in situ. Dans ce contexte, les biocapteurs sont prometteurs dans le développement de nouveaux systèmes pour une détection précoce. On peut citer deux exemples dans des domaines aussi variés que la détection précoce de corrosion bactérienne ou la détection de la formation d'espèces biologiques responsables de maladies dégénératives.Ce travail propose la conception et la réalisation d'un biocapteur pour la détection de molécules d'intérêt biologiques. La réalisation de ce biocapteur est basée sur le d
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McPhail, Deborah. "Energetics of interaction between biomolecules." Thesis, University of Glasgow, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363149.

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Bredenberg, Johan. "Modelling biomolecular interactions /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-571-9.

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Ipaud, Amandine Barbara. "Interaction of metal oxides with biomolecules." DigitalCommons@Robert W. Woodruff Library, Atlanta University Center, 2014. http://digitalcommons.auctr.edu/dissertations/1312.

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Current methods utilized for the cleanup of drinking water primarily involve the use of chemical oxidants (e.g. chlorine, chlorine dioxide, ozone) to remove harmful bacteria and other pathogens. These processes create a number of disinfection by products (DBPs) that are potent toxins including halonitro-methanes and halo-acetic acids. In our research, we sought to examine the ability of supported metal oxides to accomplish disinfection without the production of toxic DBPs. In an effort to examine the interaction of bio-molecules with metal oxides surfaces, our group used Fourier transform infr
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Weibrecht, Irene. "Visualizing Interacting Biomolecules In Situ." Doctoral thesis, Uppsala universitet, Molekylära verktyg, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-151579.

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Intra- and intercellular information is communicated by posttranslational modifications (PTMs) and protein-protein interactions, transducing information over cell membranes and to the nucleus. A cells capability to respond to stimuli by several highly complex and dynamic signaling networks provides the basis for rapid responses and is fundamental for the cellular collaborations required in a multicellular organism. Having received diverse stimuli, being positioned at various stages of the cell cycle or, for the case of cancer, containing altered genetic background, each cell in a population is
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Lechelon, Mathias. "Long-range electrodynamic interactions among biomolecules." Thesis, Aix-Marseille, 2017. http://www.theses.fr/2017AIXM0469/document.

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L’étude des organismes vivants, la biologie, s’étend sur de nombreux domaines et notamment s’applique à comprendre le fonctionnement des êtres vivants. Les organismes les plus complexes comme les êtres Humains possèdent plusieurs niveaux d’organisation : ils sont constitués successivement d’organes, de tissus, de cellules, de biomolécules. On trouve plusieurs types de biomolécules dont les protéines, qui sont comme des minuscules outils qui permettent aux cellules de vivre et d’interagir avec leur environnement. Pour cela, les protéines doivent entrer en contact les unes avec les autres de man
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Karlsson, Linda. "Biomolecular interactions with porous silicon /." Linköping : Univ, 2003. http://www.bibl.liu.se/liupubl/disp/disp2003/tek804s.pdf.

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Stocks, Matthew Benedict. "Interacting with biomolecules using haptic feedback." Thesis, University of East Anglia, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539370.

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Tiwari, Purushottam Babu. "Multimode Analysis of Nanoscale Biomolecular Interactions." FIU Digital Commons, 2015. http://digitalcommons.fiu.edu/etd/1923.

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Biomolecular interactions, including protein-protein, protein-DNA, and protein-ligand interactions, are of special importance in all biological systems. These interactions may occer during the loading of biomolecules to interfaces, the translocation of biomolecules through transmembrane protein pores, and the movement of biomolecules in a crowded intracellular environment. The molecular interaction of a protein with its binding partners is crucial in fundamental biological processes such as electron transfer, intracellular signal transmission and regulation, neuroprotective mechanisms, and reg
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Books on the topic "Interaction with biomolecule"

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Gábor, Náray-Szabó, and Simon Kálmán 1946-, eds. Steric aspects of biomolecular interactions. CRC Press, 1987.

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Patra, Abhijeet. Quantifying Interactions of Biomolecules with Inorganic Surfaces. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-30728-2.

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Kool, Jeroen, and Wilfried M. A. Niessen, eds. Analyzing Biomolecular Interactions by Mass Spectrometry. Wiley-VCH Verlag GmbH & Co. KGaA, 2015. http://dx.doi.org/10.1002/9783527673391.

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Nagata, Kazuhiro, and Hiroshi Handa, eds. Real-Time Analysis of Biomolecular Interactions. Springer Japan, 2000. http://dx.doi.org/10.1007/978-4-431-66970-8.

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V, Buckin, and Funck T, eds. Biomolecular interactions in DNA and proteins. Nova Science, 1996.

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1944-, Ngo T. T., ed. Molecular interactions in bioseparations. Plenum Press, 1993.

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Aldrich-Wright, Janice. Metallointercalators: Synthesis and Techniques to Probe Their Interactions with Biomolecules. Springer-Verlag/Wien, 2011.

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1947-, Nagata Kazuhiro, and Handa H. 1946-, eds. Real-time analysis of biomolecular interactions: Applications of BIACORE. Springer, 2000.

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Rudolf Mathias Johannes Nicolaas Lamerichs. 2D NMR studies of biomolecules: Proteins structures and protein-DNA interactions. [s.n.], 1989.

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Jia, Yuan. Polymer-Based MEMS Calorimetric Devices for Characterization of Biomolecular Interactions. [publisher not identified], 2017.

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Book chapters on the topic "Interaction with biomolecule"

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Quack, Salina, and David Dulin. "Surface Functionalization, Nucleic Acid Tether Characterization, and Force Calibration for a Magnetic Tweezers Assay." In Single Molecule Analysis. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3377-9_19.

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AbstractMagnetic tweezers are a force spectroscopy single-molecule technique. They enable the mechanical manipulation of biomolecules via the means of a magnetic particle under an attractive force applied by a magnetic field source. The magnetic particle is tethered to the glass surface of a flow chamber by the biomolecule, and functionalization strategies have been developed to reduce the nonspecific interactions of either the magnetic particles or biomolecules with the surface. Here, we describe two complementary strategies to achieve a high tether density while reducing the interactions of
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Pangule, Ravindra C., Shyam Sundhar Bale, Dhiral A. Shah, et al. "Biomolecule-Nanomaterial Interactions: Effect on Biomolecular Structure, Function, and Stability." In Biological Interactions on Materials Surfaces. Springer US, 2009. http://dx.doi.org/10.1007/978-0-387-98161-1_5.

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Ciofi-Baffoni, Simone. "Metal-Mediated Interactions." In NMR of Biomolecules. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527644506.ch10.

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Manoharan, Vijayalaxmi, Jose Manuel Pérez-Cañadillas, and Andres Ramos. "Protein-RNA Interactions." In NMR of Biomolecules. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527644506.ch12.

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Kovačič, Lidija, and Rolf Boelens. "Protein-DNA Interactions." In NMR of Biomolecules. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527644506.ch13.

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Churchich, Jorge E., and John A. Cidlowski. "Interactions Between Aminotransferases and Monoclonal Antibodies." In Fluorescent Biomolecules. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5619-6_39.

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Keizers, Peter H. J., Yoshitaka Hiruma, and Marcellus Ubbink. "Protein-Paramagnetic Protein Interactions." In NMR of Biomolecules. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527644506.ch11.

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Voss, Edward W. "Definition of Monoclonal Antibody-Fluorescent Ligand Interactions." In Fluorescent Biomolecules. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5619-6_15.

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Liu, Hong-Ke, and Peter J. Sadler. "Interactions of Metallodrugs with DNA." In NMR of Biomolecules. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527644506.ch16.

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Vigneshwaran, N., and Prateek Jain. "Biomolecules–Nanoparticles: Interaction in Nanoscale." In Metal Nanoparticles in Microbiology. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-18312-6_6.

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Conference papers on the topic "Interaction with biomolecule"

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Xu, Xitan, Yao Lu, Xinda Jiang, Qiang Wu, and Jingjun Xu. "On-chip integrated terahertz sensing platform for biomolecules." In CLEO: Science and Innovations. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/cleo_si.2024.sm2p.2.

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We present an integrated terahertz sensing platform on lithium niobate chips, with antenna arrays that guide terahertz waves transmission and enhance interaction with biomolecules. Its sensing performance is demonstrated through spectrum and dispersion relations.
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Saavedra, Carlos, Daniel Sole-Barber, Julia Rasch, Lisa-Maria Needham, and Randall Goldsmith. "Beyond Labels: Advancing Single Molecule Sensitivity with Hot Fabry-Perot Micro Cavities." In CLEO: Science and Innovations. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/cleo_si.2024.sf2a.4.

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Fiber-Fabry-Perot microcavities are tools that enhance light-matter interactions. A new detection scheme exploiting photo-thermal effects and Pound-Drever-Hall locking technique enabled label-free detection of solution-phase single biomolecules hundred times smaller than the wavelength in solution phase.
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Bhatia, Sangeeta N., Martin L. Yarmush, and Mehmet Toner. "Engineered Substrates for Controlling Cell-Cell Interactions." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-1319.

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Abstract Biomaterials have been previously engineered to serve a variety of different functions: precise degradation in vivo (Kimura, 1993), modulation of cell physiology via binding to specific ligands (Hubbell et al, 1992), and selective permeability of certain solutes (Lysaght et al, 1994). However, in complex tissues, where cell-cell interactions strongly influence tissue function, biomaterials which modulate this fundamental parameter have not been available. In this study, we describe a technique which allows control over cell-cell interactions by using semiconductor-based microfabricati
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Chung, Kyungwha, and Luke P. Lee. "Self-aligned nanoring doublet as a single particle nanocavity for strong coupling interaction with biomolecules." In Quantum Effects and Measurement Techniques in Biology and Biophotonics II, edited by Clarice Aiello, Sergey V. Polyakov, and Paige Derr. SPIE, 2025. https://doi.org/10.1117/12.3042416.

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Jan, Chia-Ming, Pei-I. Tsai, Shin-Ting Chou, Shu-Sheng Lee, and Chih-Kung Lee. "An integrated platform for biomolecule interaction analysis." In SPIE BiOS, edited by Tuan Vo-Dinh, Joseph R. Lakowicz, and Krishanu Ray. SPIE, 2013. http://dx.doi.org/10.1117/12.2002006.

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Waghmare, Prashant R., and Sushanta K. Mitra. "Mechanism of Cell Transport in a Microchannel With Binding Between Cell Surface and Immobilized Biomolecules." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-12691.

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Recent trends in micro and nano fabrication techniques have opened a new era for microfluidic based immunosensing devices. In immunosensing microfluidic device, the buffer solution transports the different biomolecules and cells. The interaction between the cell and surface of the microchannel takes place during this transport. In the present study, the effect of interaction between the cell and the immobilized biomolecule on the cell transport is analyzed theoretically. A single cell transport is studied with the interaction between the cell surface and the microchannel wall. The type of immo
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Zhou, Ling-Yun, Canbang Zhang, and Yiying Zhou. "Quantum mechanics analysis of damping effect on laser-biomolecule interaction." In Biomolecular photonoics and Multidimensional Microscopy, edited by Qingming Luo and Min Gu. SPIE, 2003. http://dx.doi.org/10.1117/12.546253.

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Zhou, Yiying, Ling-Yun Zhou, and Ruili Wang. "Micromechanism analysis on temperature-rising effect of CO 2 laser biomolecule interaction." In International Symposium on Biomedical Optics, edited by Qingming Luo, Britton Chance, Lihong V. Wang, and Steven L. Jacques. SPIE, 1999. http://dx.doi.org/10.1117/12.364424.

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Vezzoli, G. C. "Physics and capabilities of terahertz spectroscopy to study the water-biomolecule interaction." In Optics East 2007, edited by Mehdi Anwar, Anthony J. DeMaria, and Michael S. Shur. SPIE, 2007. http://dx.doi.org/10.1117/12.754472.

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Mufeed, Mohd, Ankit Sirohi, and Jawar Singh. "Physisorption Interaction of Nucleobases on ZrGeTe4 Using Density Functional Theory Study for Biomolecule Sensing." In 2024 8th IEEE Electron Devices Technology & Manufacturing Conference (EDTM). IEEE, 2024. http://dx.doi.org/10.1109/edtm58488.2024.10511446.

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Reports on the topic "Interaction with biomolecule"

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Li, Dongsheng, and Zexi Lu. In situ study of Crystal Surface Interactions Guided by Biomolecules or Ligands. Office of Scientific and Technical Information (OSTI), 2021. http://dx.doi.org/10.2172/1987565.

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Kotula, Paul Gabriel, Susan Marie Brozik, Komandoor E. Achyuthan, et al. Biomolecular interactions and responses of human epithelial and macrophage cells to engineered nanomaterials. Office of Scientific and Technical Information (OSTI), 2011. http://dx.doi.org/10.2172/1034881.

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French, Roger H., Nicole F. Steinmetz, and Yingfang Ma. Long Range van der Waals - London Dispersion Interactions For Biomolecular and Inorganic Nanoscale Assembly. Office of Scientific and Technical Information (OSTI), 2018. http://dx.doi.org/10.2172/1431216.

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Hummer, G., A. E. Garcia, and D. M. Soumpasis. Potential-of-mean-force description of ionic interactions and structural hydration in biomolecular systems. Office of Scientific and Technical Information (OSTI), 1994. http://dx.doi.org/10.2172/10186924.

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Graves, David Barry. Collaborative Research: Atmospheric Pressure Plasma-Biomaterial Surface Interactions - Bridging Understanding of APP Sources to Rational Modification of Biomolecules. Office of Scientific and Technical Information (OSTI), 2017. http://dx.doi.org/10.2172/1410180.

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Chefetz, Benny, Baoshan Xing, and Yona Chen. Interactions of engineered nanoparticles with dissolved organic matter (DOM) and organic contaminants in water. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7699863.bard.

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Background: Engineered carbon nanotubes (CNTs) are expected to be increasingly released into the environment with the rapid increase in their production and use. The discharged CNTs may interact with coexisting contaminants and subsequently change environmental behaviors and ecological effects of both the CNTs themselves and the contaminants. Dissolved organic matter (DOM) plays a critical role in the transport of CNTs in the aquatic environment, affecting both CNT's surface properties through adsorption, and its colloidal stability in solution. Therefore, CNT-bound DOM complexes may interact
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Rodriguez Muxica, Natalia. Open configuration options Bioinformatics for Researchers in Life Sciences: Tools and Learning Resources. Inter-American Development Bank, 2022. http://dx.doi.org/10.18235/0003982.

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The COVID-19 pandemic has shown that bioinformatics--a multidisciplinary field that combines biological knowledge with computer programming concerned with the acquisition, storage, analysis, and dissemination of biological data--has a fundamental role in scientific research strategies in all disciplines involved in fighting the virus and its variants. It aids in sequencing and annotating genomes and their observed mutations; analyzing gene and protein expression; simulation and modeling of DNA, RNA, proteins and biomolecular interactions; and mining of biological literature, among many other c
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