Relevant bibliographies by topics / Jaw disease

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Jaw disease'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Jaw disease"

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Furkhatovich, Farkhatov Sunnatillokhan, and Akhmedov Alisher Astanovich. "Periodontal Disease - Symptoms and Treatment." Journal of Social Sciences and Humanities Research Fundamentals 5, no. 1 (2025): 81–87. https://doi.org/10.55640/jsshrf-05-01-14.

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Periodontal disease is a disease of periodontal tissues of a dystrophic nature. Periodontal tissues include tissues whose main task is to hold the tooth in the jaw bone. These include: the gum; the ligamentous apparatus that holds the tooth — the periodontium; the tooth cement — the outer surface of the tooth covering its root; and the alveolar part of the jaw bone.
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Sumner, C. J., and K. H. Fischbeck. "Jaw drop in Kennedy's disease." Neurology 59, no. 9 (2002): 1471–72. http://dx.doi.org/10.1212/01.wnl.0000033325.01878.13.

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Keller, E. "Jaw Deformity Secondary to Still's Disease." Seminars in Plastic Surgery 3, no. 01 (1989): 140–44. http://dx.doi.org/10.1055/s-2008-1080484.

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Rong, Panying. "The Effect of Tongue–Jaw Coupling on Phonetic Distinctiveness of Vowels in Amyotrophic Lateral Sclerosis." Journal of Speech, Language, and Hearing Research 62, no. 9 (2019): 3248–64. http://dx.doi.org/10.1044/2019_jslhr-s-19-0058.

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Purpose The aim of this study was to determine the relation of tongue–jaw coupling to phonetic distinctiveness of vowels in persons at different stages (i.e., early, middle, late) of bulbar motor involvement in amyotrophic lateral sclerosis (ALS) and healthy controls. Method The pattern of spatial tongue–jaw coupling was derived from 11 individuals with ALS and 11 healthy controls using the parallel factor analysis. Two articulatory components, which correspond to tongue displacement independent of the jaw (iTongue) and jaw contribution to tongue displacement (cJaw), were extracted from the co
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Robertson, Lee T., Rebecca J. St George, Patricia Carlson-Kuhta, Penelope Hogarth, Kim J. Burchiel, and Fay B. Horak. "Site of deep brain stimulation and jaw velocity in Parkinson disease." Journal of Neurosurgery 115, no. 5 (2011): 985–94. http://dx.doi.org/10.3171/2011.7.jns102173.

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Object While deep brain stimulation (DBS) has proven to be an effective treatment for many symptoms of Parkinson disease (PD), a deterioration of axial symptoms frequently occurs, particularly for speech and swallowing. These unfavorable effects of DBS may depend on the site of stimulation. The authors made quantitative measures of jaw velocity to compare the relative effectiveness of DBS in the globus pallidus internus (GPi) or the subthalamic nucleus (STN). This was a randomized, double-blind, and longitudinal study, with matched healthy controls. Methods The peak velocities of self-scaled a
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Peck, Christopher C., Alexander Wirianski, and Greg M. Murray. "Jaw motor plasticity in health and disease." Computer Methods in Biomechanics and Biomedical Engineering 13, no. 4 (2010): 455–58. http://dx.doi.org/10.1080/10255840903453090.

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Zeman-Kuhnert, Katharina, Alexander J. Gaggl, Gian B. Bottini, et al. "Dental Rehabilitation After Microvascular Reconstruction of Segmental Jaw Defects: A Ten-Year Follow-Up." Journal of Clinical Medicine 14, no. 2 (2025): 628. https://doi.org/10.3390/jcm14020628.

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Background/Objectives: Defects in maxillary and mandibular continuity are common in maxillofacial practice. They can occur after trauma, osteonecrosis, congenital jaw deformities, or surgical resection of benign or malignant tumours. Reconstruction with microvascular bone flaps and subsequent prosthetic rehabilitation is considered the contemporary first line treatment. This study assessed the extent to which the underlying disease influences the treatment course of microvascular segmental jaw reconstruction. Methods: A retrospective review of prospectively collected data from all patients who
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Kaur, Harsimran, Jyoti, Gursharan Kaur, and Parminder Kaur. "A literature review on various diagnostic modalities and treatment options for the treatment of the osteomyelitis of the jaw." IP International Journal of Maxillofacial Imaging 9, no. 4 (2024): 172–75. http://dx.doi.org/10.18231/j.ijmi.2023.029.

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Osteomyelitis of the jaw is found to be the most common disease affecting the maxillofacial region. Osteomyelitis is found to be true bacterial infection affecting the jaw bone. Different types of osteomyelitis which are distinguishable are acute osteomyelitis, primary chronic osteomyelitis and secondary chronic osteomyelitis of the jaw. The main characteristic features of the osteomyelitis of the jaw are, formation of the fistula, suppuration, and sequestration of the jaw bone. Different treatment modalities of the osteomyelitis of the jaw include surgery, debridement of the lesion superficia
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Harcourt‐Brown, Frances. "Dental disease in pet rabbits 3. Jaw abscesses." In Practice 31, no. 10 (2009): 496–505. http://dx.doi.org/10.1136/inpract.31.10.496.

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Jeurissen, S. E. R. "Case Number 27: Jaw claudication in Takayasu's disease." Annals of the Rheumatic Diseases 62, no. 10 (2003): 922. http://dx.doi.org/10.1136/ard.62.10.922.

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Dissertations / Theses on the topic "Jaw disease"

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Panta, Utsab, Adam chan, and Debalina Das. "Osteonecrosis of Jaw: Common etiologies, uncommon treatments." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/201.

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Introduction First described in 2002, osteonecrosis of the jaw (ONJ, or avascular necrosis of the jaw) is an uncommon but potentially serious side effect of treatment with bisphosphonates. Although typically identified in patients with multiple myeloma and other malignancies, a few cases have been reported in patients taking bisphosphonates - a potent drug class used in the treatment of osteoclast-mediated bone resorption issues, including postmenopausal osteoporosis, Paget's disease, multiple myeloma, and malignant hypercalcemia. The clinical diagnosis of ONJ can be obscured by jaw pain, absc
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Asperger, Michael. "Zur Ätiologie und Bekämpfung der Lumpy jaw disease bei Kängurus." [S.l.] : [s.n.], 2003. http://dol.uni-leipzig.de/pub/2003-36.

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Asperger, Michael. "Zur Ätiologie und Bekämpfung der Lumpy Jaw Disease bei Kängurus." Doctoral thesis, Universitätsbibliothek Leipzig, 2004. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-37575.

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In der vorliegenden Arbeit sollten die in der veterinärmedizinischen Literatur bisher diskutierten Ursachen für LJD bei Makropoden hinsichtlich ihrer tatsächlichen Bedeutung abgeklärt und die Eignung einer formalininaktivierten, bestandsspezifischen Adsorbatvakzine zur Prophylaxe von LJD getestet werden. Da LJD eine parodontale Erkrankung darstellt, wurden auch die für Entstehung einer humanen Parodontitis prädisponierenden Faktoren mit in die Untersuchung einbezogen. Es wurden Tupferproben zur bakteriologischen Untersuchung von insgesamt 15 gesunden und 11 an LJD erkrankten Kängurus entnommen
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Wackermann, Felix [Verfasser]. "Radiologische Untersuchungen und Klassifizierung der Lumpy Jaw Disease bei im Zoo gehaltenen Kängurus / Felix Wackermann." Hannover : Stiftung Tierärztliche Hochschule Hannover, 2019. http://d-nb.info/1202272398/34.

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Rendle, Jessica Amy Jane. "Epidemiology of lumpy jaw in captive macropods across Australia and Europe: An investigation of disease risk and treatment approaches." Thesis, Rendle, Jessica Amy Jane (2019) Epidemiology of lumpy jaw in captive macropods across Australia and Europe: An investigation of disease risk and treatment approaches. PhD thesis, Murdoch University, 2019. https://researchrepository.murdoch.edu.au/id/eprint/49721/.

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Lumpy jaw is a well-recognised cause of morbidity and mortality in captive macropods (Macropodidae) worldwide. The extent and causes of the disease are largely unknown, although multiple risk factors associated with a captive environment are thought to contribute to the development of clinical disease. Identification of risk factors associated with lumpy jaw would assist with the development of preventive management strategies, potentially reducing mortalities. A cross-sectional study was undertaken from 2011 to 2015, to determine prevalence and risk factors for this disease through the di
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Mahaini, Mohamad Salah Aldin [Verfasser], and Sven [Akademischer Betreuer] Otto. "Bacterial osteomyelitis versus diffuse sclerosing osteomyelitis of the jaw, similar nomenclature, different disease entity / Mohamad Salah Aldin Mahaini ; Betreuer: Sven Otto." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2018. http://d-nb.info/1164376993/34.

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Panya, Sappasith [Verfasser], and Sven [Akademischer Betreuer] Otto. "A microbiological study of medication-related osteonecrosis of the jaw (MRONJ) and actinomyces involvement in the disease / Sappasith Panya ; Betreuer: Sven Otto." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2018. http://d-nb.info/1154683850/34.

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Villablanca, Andrea. "Genetic background of familial primary hyperparathyroidism /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-520-4/.

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Ryan, Paul Leo. "The characterisation of human γδ T cells in health and disease : do Vγ9Vδ2 T cells play a role in the pathogenesis of Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ)?" Thesis, Queen Mary, University of London, 2014. http://qmro.qmul.ac.uk/xmlui/handle/123456789/9006.

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Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) is a chronic necrosis of the jawbone that occurs in ≈1-5% of patients receiving bisphosphonate medication for conditions such as osteoporosis and certain cancers. Although the pathogenesis of BRONJ is still uncertain, several recent theories have emerged; these include vascular disruption of the jaw tissue; inappropriate osteoclast activation; and direct cytotoxicity of jaw epithelium. However, despite bisphosphonates having well-documented stimulatory effects on immune cells, and BRONJ being associated with oral microbial infections, an
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Sae-Lee, Daraporn. "Effects Of Experimentally Induced Jaw Muscle Pain On Jaw Muscle Activity And Jaw Movement During Standardized Jaw Tasks." Thesis, The University of Sydney, 2007. http://hdl.handle.net/2123/4969.

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Books on the topic "Jaw disease"

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Waal, Isaäc van der. Diseases of the jaws: Diagnosis and treatment : textbook & atlas. Munksgaard, 1991.

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Waal, Isaäc van der. Diseases of the jaws: Diagnosis and treatment : textbook & atlas. Munksgaard, 1991.

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Anthony, Taylor, ed. Neurophysiology of the jaws and teeth. Macmillan Scientific & Medical, 1990.

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Diane, Stern, ed. Oral and maxillofacial pathology: A rationale for diagnosis and treatment. 2nd ed. Quintessence Pub. Co., 2012.

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Wannfors, Karin. Chronic osteomyelitis of the jaws. Gotab, 1990.

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Wannfors, Karin. Chronic osteomyelitis of the jaws. School of Dentistry, Karolinska Institutet, 1990.

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A, De Laat, Steenberghe D. van, and International Association for Dental Research., eds. Electromyography of jaw reflexes in man: Proceedings of the I.A.D.R. satellite symposium held at the Catholic University Leuven. Leuven University Press, 1989.

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van, Steenberghe Daniel, De Laat A, and International Association for Dental Research., eds. Electromyography of jaw reflexes in man: Proceedings of the I.A.D.R. satellite symposium held at the Catholic University Leuven. Leuven University Press, 1989.

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Anastasis, Stephanou, ed. JAK-STAT pathway in disease. Landes Bioscience, 2009.

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Ponte, Francesco Saverio De. Bisphosphonates and osteonecrosis of the jaw: A multidisciplinary approach. Springer, 2012.

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Book chapters on the topic "Jaw disease"

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Badros, Ashraf. "Osteonecrosis of the Jaw." In Myeloma Bone Disease. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-554-5_7.

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Zavras, Athanasios. "Bisphosphonate Related Osteonecrosis of the Jaw." In Genomics, Personalized Medicine and Oral Disease. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-17942-1_14.

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Calabria, Andrew C., and Michael A. Levine. "Hyperparathyroidism–Jaw Tumor Syndrome." In Diseases of the Parathyroid Glands. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-5550-0_13.

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van der Waal, Isaäc. "Diseases of the Jaw Bones." In Atlas of Oral Diseases. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-48122-6_7.

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He, Yue, Hui Shan Ong, Zhen Tian, Lin Zhu, and Hang Chen. "Medication-Related Osteonecrosis of Jaw." In Inflammatory and Neoplastic Diseases of Craniofacial Bones. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-4155-7_4.

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He, Yue, Hui Shan Ong, Zhen Tian, Lin Zhu, and Jie He. "Garré’s Osteomyelitis of the Jaw." In Inflammatory and Neoplastic Diseases of Craniofacial Bones. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-4155-7_2.

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Caldow, Marissa K., and David Cameron-Smith. "JAK." In Encyclopedia of Exercise Medicine in Health and Disease. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-29807-6_2575.

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Gordon, Peter, and Michael Perry. "The Lower Jaw (Mandible) and Associated Structures: Part III Injuries to the Lower Jaw." In Diseases and Injuries to the Head, Face and Neck. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-53099-0_23.

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Rath, P. D., S. S. Nelson, and A. K. Khan. "JAK Inhibitors in Rheumatic Disease." In Handbook of Biologics for Rheumatological Disorders. Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-7200-2_18.

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Esposito, Giuseppe, Martina Sebök, Jorn Fierstra, and Luca Regli. "Flow-Augmentation Bypass Surgery: Indications and Decision-Making." In Acta Neurochirurgica Supplement. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-89844-0_14.

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Abstract Flow-augmentation bypass aims to enhance blood flow to hypoperfused brain regions in patients with cerebrovascular steno-occlusive diseases. This surgical procedure is indicated for ischemic and hemorrhagic moyamoya vasculopathy and for selected patients with chronic steno-occlusive disease and acute ischemic stroke. Flow-augmentation bypass has been rigorously evaluated in randomized clinical trials, including the EC-IC Bypass Trial, the Carotid Occlusion Surgery Study (COSS), the Japanese Adult Moyamoya (JAM) trial, and the recent Carotid and Middle Cerebral Artery Occlusion Surgery
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Conference papers on the topic "Jaw disease"

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Madany, Mohamed E., Ayman Khalafallah, Magdy A. Ahmed, and Amin Shoukry. "Diagnosis of Parkinson’s disease using Kolmogorov-Arnold Networks." In 2024 12th International Japan-Africa Conference on Electronics, Communications, and Computations (JAC-ECC). IEEE, 2024. https://doi.org/10.1109/jac-ecc64419.2024.11061201.

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Palhang, Meejan, N. Charles, and Francois Gould. "Swallowing Disrupts Tongue-Jaw Coordination During Chewing in a Rat Model of Parkinson's Disease." In 27th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2023. https://doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.127_2023.

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The primary motor symptoms of Parkinson’s disease, including bradykinesia, rigidity, and tremor, are associated with difficulties regulating transitions between motor behaviors due to basal ganglia dysfunction. Chewing and swallowing, which are disordered in most patients with Parkinson’s disease, are two complex motor behaviors which overlap in time and share some neuromuscular components. The objective of this study is to identify how Parkinson’s disease affects the coordination of chewing and swallowing. We hypothesize that as a result of impaired regulation of shift between motor patterns,
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Zanghi, Nicholas, Taylor Good, Shivam Patel, and Francois Gould. "Identifying Chewing Alterations in a Parkinsonian Model." In 28th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2024. http://dx.doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.14_2024.

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Patients suffering from Parkinson’s Disease will typically experience a range of motor and nonmotor symptoms. Characteristic signs of Parkinson’s include pill-rolling tremor, stooped posture, and shuffling gate. Patients with this disease can also develop oropharyngeal dysfunction, which can disable patients from meeting their physiologic needs. Understanding this disability and the changes in mastication kinematics can lead to potential future treatment. Our study induced Parkinson’s in rats with rotenone injections. Their jaw kinematics were identified through fluoroscopy of radio-opaque bea
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Kuruvilla-Dugdale, Mili, and Antje Mefferd. "Spatiotemporal Coupling of the Jaw and Lower Lip: Comparing Talkers with Parkinson's Disease and Amyotrophic Lateral Sclerosis." In ISSP 2024 - 13th International Seminar on Speech Production. ISCA, 2024. http://dx.doi.org/10.21437/issp.2024-29.

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Filpo, Alessandra, Caio Disserol, Bernardo Corrêa de Almeida Teixeira, Kenzo Hokazono, and Hélio A. G. Teive. "An Unexpected Smile: risus sardonicus and wing-beating tremor in a first office visit." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.505.

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Context: We present a noteworthy reminder of Wilson disease’s classical manifestations, which may become rarer in clinical practice as availability of genetic tests increases, allowing timely diagnosis and treatment. Case report: A 29 year-old woman developed progressive and asymmetric upper limb tremor and dystonia over 1 year, along with speech and feeding impairment in the last two weeks. Examination revealed segmental dystonia with risus sardonicus, open-jaw oromandibular and severe left arm dystonia, along with wing-beating tremor. Bilateral Kayser-Fleischer ring, low serum ceruloplasmin
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Kashi, Ajay, Amit Roy Chowdhury, and Subrata Saha. "Finite Element Analysis of TMJ Implant." In ASME 2009 4th Frontiers in Biomedical Devices Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/biomed2009-83052.

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The TMJ is a bilateral joint of the jaw that functions as a single entity during normal masticatory activities, speaking, yawning and swallowing. TMJ replacement has been indicated in cases of joint trauma, advanced degenerative disease, tumors, developmental anomalies and ankylosis of the joint following injury. Alloplastic replacement of the TMJ (an artificial replacement in the form of a TMJ condylar implant with a glenoid fossa component that articulates with the undersurface of the skull on the temporal bone) renders the anatomical space devoid of the natural mandibular condyle (Fig. 1).
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Alapatt, Catherine F., Amanda Greenspan, and Mohammad Fardos. "Janus Kinase (JAK) Inhibitors: A New Frontier in the Treatment of Vitiligo." In 28th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2024. http://dx.doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.180_2024.

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Up to 70 million people worldwide suffer from vitiligo, an autoimmune disease characterized by the destruction of melanin. Current treatment options vary in efficacy. The disease manifests clinically as white circular macules of depigmentation seen primarily on the face and appendages.1 The pathophysiology of vitiligo is multifactorial and still being studied. One proposed mechanism behind the pathophysiology of vitiligo involves the upregulation of interferon gamma (IFN-γ) with downstream effects on JAK/STAT pathways resulting in CXCL10 transcription.1,2 Here we discuss Ruxolitinib, a topical
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Chaudhuri, Swapnil. "CRUSHED TO DEATH: HEALTH AND SAFETY RIGHTS OF STONE CRUSHERS IN NORTH BENGAL, INDIA." In Bangkok – International Conference on Social Science & Humanities, 08-09 July 2025. Global Research & Development Services Publishing, 2025. https://doi.org/10.20319/icssh.2025.289305.

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Silicosis, among the stone crushing laborers, is considered one of the most common fatal occupational health hazards. Various forms of crushed stone play an extremely important role in urbanization. However, a lack of awareness and the degraded working environment often deny the basic right to health and safe working conditions for stone crushers, the backbone of development worldwide. Masonry workers develop this incurable and irreparable disease due to constant inhalation of crystalline silica particles, which are commonly found in most natural and engineered stones worldwide. Over 200 migra
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Kuznetsov, A. V., A. A. Avramenko, and D. G. Blinov. "Simulation of Traffic Jam Formation in Fast Axonal Transport." In ASME 2009 Heat Transfer Summer Conference collocated with the InterPACK09 and 3rd Energy Sustainability Conferences. ASMEDC, 2009. http://dx.doi.org/10.1115/ht2009-88345.

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Many neurodegenerative diseases, such as Alzheimer’s disease, are linked to swellings occurring in long arms of neurons. Many scientists believe that these swellings result from traffic jams caused by the failure of intracellular machinery responsible for fast axonal transport; such traffic jam can plug an axon and prevent the sufficient amount of organelles to be delivered toward the synapse of the axon. Mechanistic explanation of the formation of traffic jams in axons induced by overexpression of tau protein is based on the hypothesis that the traffic jam is caused not by the failure of mole
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Lini, Priscila, André Luis Ramos Soares, and Maria da Gloria Tavares Demamann. "Human skull with TMJ and secondary comorbidities: Study in university collection." In II Seven International Education Congress. Seven Congress, 2024. http://dx.doi.org/10.56238/iieducationcongress-017.

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Temporomandibular joint ankylosis (TMJA) is a disabling condition characterized by bone or fibrous adhesion, resulting in loss of joint function. It can cause severe limitations in jaw movements, affecting chewing, speech and breathing, and generating psychological stress. Classified according to the location and type of tissue involved, TMJA can occur due to trauma, infections or autoimmune diseases. In the clinical case analyzed, complete bone fusion of the joint was observed, associated with nutritional deficiencies and other comorbidities, evidenced by specific characteristics of the skull
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Reports on the topic "Jaw disease"

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Manulis, Shulamit, Christine D. Smart, Isaac Barash, Guido Sessa, and Harvey C. Hoch. Molecular Interactions of Clavibacter michiganensis subsp. michiganensis with Tomato. United States Department of Agriculture, 2011. http://dx.doi.org/10.32747/2011.7697113.bard.

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Clavibacter michiganensis subsp. michiganensis (Cmm), the causal agent of bacterial wilt and canker of tomato, is the most destructive bacterial disease of tomato causing substantial economic losses in Israel, the U.S.A. and worldwide. The molecular strategies that allow Cmm, a Gram-positive bacterium, to develop a successful infection in tomato plants are largely unknown. The goal of the project was to elucidate the molecular interactions between Cmmand tomato. The first objective was to analyze gene expression profiles of susceptible tomato plants infected with pathogenic and endophytic Cmms
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Chefetz, Benny, Baoshan Xing, Leor Eshed-Williams, Tamara Polubesova, and Jason Unrine. DOM affected behavior of manufactured nanoparticles in soil-plant system. United States Department of Agriculture, 2016. http://dx.doi.org/10.32747/2016.7604286.bard.

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The overall goal of this project was to elucidate the role of dissolved organic matter (DOM) in soil retention, bioavailability and plant uptake of silver and cerium oxide NPs. The environmental risks of manufactured nanoparticles (NPs) are attracting increasing attention from both industrial and scientific communities. These NPs have shown to be taken-up, translocated and bio- accumulated in plant edible parts. However, very little is known about the behavior of NPs in soil-plant system as affected by dissolved organic matter (DOM). Thus DOM effect on NPs behavior is critical to assessing the
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Laxmi Prasanna, Porandla, B. Anil kumar, and Macha Sahithi. A STUDY TO EVALUATE THE TEAR FILM CHANGES IN PATIENTS WITH PTERYGIUM. World Wide Journals, 2023. http://dx.doi.org/10.36106/ijar/3408221.

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Introduction: Pterygium is a degenerative condition of the subconjunctival tissues which proliferate as vascularized granulation tissue to invade the cornea, destroying the supercial layers of the stroma and bowmans membrane, the whole being covered by conjunctival epithelium.The tear lm consists of three layers, the most supercial layer of tear lm is lipid layer produced by meibomian glands. The middle layer is the aqueous layer produced by the main lacrimal gland as well as accessory lacrimal glands of Krause and Wolfring. Aqueous layer constitutes over 90% of the tear lm. The layer clo
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