Academic literature on the topic 'Liposome structure'

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Journal articles on the topic "Liposome structure"

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Kumar, Amit, Madhu Gupta, and Simran Braya. "Liposome Characterization, Applications and Regulatory landscape in US." International Journal of Drug Regulatory Affairs 9, no. 2 (2021): 81–89. http://dx.doi.org/10.22270/ijdra.v9i2.474.

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Liposomes are lipid based drug carrier whose therapeutic performance depends on their structure. Liposomes offer several advantages over the conventional drug like target drug delivery, reduced toxicity, and extended pharmacokinetics. Characterization and Identification of critical attribute of liposomal formulation and suitable strategies for control during product development is important for quality of the liposomal drug product. This paper discusses the current status of the liposomal drug product and strategy used in regulating liposome product. Despite of lack of regulatory guidelines ma
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Al Badri, Yaqeen Nadheer, Cheng Shu Chaw, and Amal Ali Elkordy. "Insights into Asymmetric Liposomes as a Potential Intervention for Drug Delivery Including Pulmonary Nanotherapeutics." Pharmaceutics 15, no. 1 (2023): 294. http://dx.doi.org/10.3390/pharmaceutics15010294.

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Liposome-based drug delivery systems are nanosized spherical lipid bilayer carriers that can encapsulate a broad range of small drug molecules (hydrophilic and hydrophobic drugs) and large drug molecules (peptides, proteins, and nucleic acids). They have unique characteristics, such as a self-assembling bilayer vesicular structure. There are several FDA-approved liposomal-based medicines for treatment of cancer, bacterial, and viral infections. Most of the FDA-approved liposomal-based therapies are in the form of conventional “symmetric” liposomes and they are administered mainly by injection.
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Dhillon, Anjali, RituVinay Singh, and Kishna Ram Senwar. "An Extensive Review on Novel Liposomes : Classification, Methodology, Characterization, Current Formulations." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 03 (2024): 1842–52. http://dx.doi.org/10.25258/ijddt.14.3.83.

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Liposomes are vesicles consisting of a phospholipid, hydrophobic drug, hydrophobic tail, hydrophilic tail, cholesterol, targeting agents, positive and negatively charged lipids, and a drug encapsulated in the center of the phospholipid group having a spherical shape. The phospholipid consists of an equal number of aqueous membranes, making the liposomes an important nanocarrier for the drug delivery to the targeted site. Various liposome-based products have recently been approved and are in clinical trials. This review will discuss the structure, classification, types, and method of liposome p
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Nalawade, Vishwajit, and Kunal Patil. "Liposome: A Novel Drug Delivery System." International Journal of Research Publication and Reviews 04, no. 01 (2022): 1795–801. http://dx.doi.org/10.55248/gengpi.2023.4148.

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Liposome was derived from two Greek words “Lipos meaning fat and Soma meaning body”. Liposome were spherical shaped vesicles consist of phospholipids and cholesterol. Due to their size hydrophobic and lipophilic character they are very promising system for drug delivery. This novel drug delivery system aims to target the drug directly to the site of action. Liposomes are very biocompatible and stable and have unique property to entrap both hydrophilic drug and lipophilic drug to its compartment and lead to controlled release effect. They are of 0.05- 5.0 micrometer in diameter. Liposomes are u
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Tretiakova, Daria, Maria Kobanenko, Irina Le-Deygen, et al. "Spectroscopy Study of Albumin Interaction with Negatively Charged Liposome Membranes: Mutual Structural Effects of the Protein and the Bilayers." Membranes 12, no. 11 (2022): 1031. http://dx.doi.org/10.3390/membranes12111031.

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Liposomes as drug carriers are usually injected into the systemic circulation where they are instantly exposed to plasma proteins. Liposome–protein interactions can affect both the stability of liposomes and the conformation of the associated protein leading to the altered biodistribution of the carrier. In this work, mutual effects of albumin and liposomal membrane in the course of the protein’s adsorption were examined in terms of quantity of bound protein, its structure, liposome membrane permeability, and changes in physicochemical characteristics of the liposomes. Fluorescence spectroscop
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Mursheda*1, Ajith Chandran2 Anagha S. Raj3 Jasnath. P. "Perspectives On Liposomes: Recent Developments, Clinical Uses, And Prospects." International Journal in Pharmaceutical Sciences 2, no. 7 (2024): 1073–84. https://doi.org/10.5281/zenodo.12739742.

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Liposomes are widely recognized as a significant nanoscale drug delivery method with appealing characteristics, including an easy-to-prepare bilayer structure that assembles the cellular membrane and high biocompatibility. Over the past few decades, a great deal of work has gone into developing liposome-based drug delivery systems. Numerous drug candidates have been investigated for their potential to reduce toxicity and prolong the duration of therapeutic effect by encapsulating them in liposomes. A growing number of liposomal-based therapeutics, with a variety of uses in antiviral, anticance
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Toopkanloo, Sahar Pakbaten, Tai Boon Tan, Faridah Abas, Mohammad Azam, Imededdine Arbi Nehdi, and Chin Ping Tan. "Improving Vesicular Integrity and Antioxidant Activity of Novel Mixed Soy Lecithin-Based Liposomes Containing Squalene and Their Stability against UV Light." Molecules 25, no. 24 (2020): 5873. http://dx.doi.org/10.3390/molecules25245873.

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In order to improve the membrane lipophilicity and the affinity towards the environment of lipid bilayers, squalene (SQ) could be conjugated to phospholipids in the formation of liposomes. The effect of membrane composition and concentrations on the degradation of liposomes prepared via the extrusion method was investigated. Liposomes were prepared using a mixture of SQ, cholesterol (CH) and Tween80 (TW80). Based on the optimal conditions, liposome batches were prepared in the absence and presence of SQ. Their physicochemical and stability behavior were evaluated as a function of liposome cons
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Adler-Moore, Jill, and Richard T. Proffitt. "AmBisome: liposomal formulation, structure, mechanism of action and pre-clinical experience." Journal of Antimicrobial Chemotherapy 49, suppl_1 (2002): 21–30. http://dx.doi.org/10.1093/jac/49.suppl_1.21.

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Abstract Amphotericin B is the treatment of choice for life-threatening systemic fungal infections such as candidosis and aspergillosis. To improve this drug's efficacy and reduce its acute and chronic toxicities, several lipid formulations of the drug have been developed, including AmBisome, a liposomal formulation of amphotericin B. The liposome is composed of high transition temperature phospholipids and cholesterol, designed to incorporate amphotericin B securely into the liposomal bilayer. AmBisome can bind to fungal cell walls, where the liposome is disrupted. The amphotericin B, after b
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Ayush, S. Jaiswal*1 Rekha Gaukande2 Gajanan Sanap3. "A Review On Liposomes As Drug Delivery System." International Journal in Pharmaceutical Sciences 1, no. 12 (2023): 926–36. https://doi.org/10.5281/zenodo.10442217.

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Liposomes are composed of phospholipids and lipids, forming spherical or multilayered vesicles with a lipid bilayer structure in aqueous solutions due to self-assembly of diacyl chain phospholipids. The number of bilayers and the size of vesicles influence the amount of drug encapsulation in liposomes, a crucial factor in determining their circulation half-life. This method involves coating a medication and a lipid onto a soluble carrier to create a pro-liposome, which is free-flowing and granular. When hydrated, it forms an isotonic liposomal solution. This pro-liposome approach serves as a m
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Maneri, Karishma Y* Inagle Sanjay Baride komal Latpate Manisha B. "Liposomal Nanomedicines In Cancer Therapy." International Journal of Pharmaceutical Sciences 2, no. 10 (2024): 1537–52. https://doi.org/10.5281/zenodo.13997934.

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As nanocarriers, liposomes have long been studied for their ability to deliver medications to their sites of action while lowering toxicity.Nanotechnology is among the most exciting new technologies of the twenty-first century.Phospholipids give liposomes their form. Anticancer medications, among other medications, can be delivered by liposome encapsulation. Liposomes can include both hydrophilic and hydrophobic medicines. Once closed lipid bilayer vesicles were discovered, the name liposomes was first used in 1960. As medication carriers, liposomes are helpful, but making them using organic s
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Dissertations / Theses on the topic "Liposome structure"

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Johnsson, Markus. "Sterically stabilised liposomes and related lipid aggregates : Fundamental studies on aggragate structure and stability." Doctoral thesis, Uppsala University, Department of Physical Chemistry, 2001. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-663.

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<p>Various aspects of and approaches towards the steric stabilisation of liposomes have been investigated, mainly by use of fluorescence techniques and cryo-transmission electron microscopy (cryo-TEM). It is shown that PEG(2000)-lipids can be incorporated in the liposome membrane up to a critical concentration of 8-10 mol% without any observable structural perturbations. Above 10 mol%, a breakdown of the liposome structure into flat lamellar discs was observed. The sterically stabilised liposomes displayed similar, or even reduced, membrane permeability as compared with conventional liposomes.
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Baudon, Béatrice. "Propriétés physicochimiques de la bactériorhodopsine." Bordeaux 2, 1996. http://www.theses.fr/1996BOR2P066.

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CALANDRO, PIERPAOLO. "Development of liposome-based drug delivery system to improve drug-like properties and anticancer activity of tyrosine kinase inhibitors with pyrazolo [3,4-d] pyrimidine structure." Doctoral thesis, Università degli studi di Siena, 2017. http://hdl.handle.net/11365/1004793.

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Cancer is a multifactorial disease whose causes are still unknown. Frequently, mutations in several genes play an important role in cellular growth processes and, based on their specific roles, they are usually distinguished in proto-oncogenes and oncosuppressors. One of the most studied oncogenes is c-Src, encoding for a non-receptor tyrosine kinase protein that plays a multitude of roles in cell signalling. The activation of c-Src is involved in the control of many functions, including cell adhesion, growth, movement, and differentiation by a different set of cell surface receptors. c-Src is
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Svangård, Erika. "Cytotoxic Cyclotides : Structure, Activity, and Mode of Action." Doctoral thesis, Uppsala universitet, Institutionen för läkemedelskemi, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6028.

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Cyclotides are small cyclic plant proteins, and this thesis addresses their cytotoxic structure-activity properties and their mode of action on human cancer cell lines. Cyclotides were isolated from Viola odorata and Viola tricolor; three novel cyclotide sequences and two known sequences, but of new origin, were identified using mass spectrometry, amino acid analysis, and Edman degradation. The cyclotide structure includes three disulphide bonds in a knotted arrangement, which forces hydrophobic amino acid residues to be exposed on the surface of the molecule; 3-D homology models of cyclotides
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Петрова, Е. А., Е. И. Дубатовка та Т. И. Терпинская. "Создание липосомных наноконструкций, меченных флуоресцентными полупроводниковыми нанокристаллами". Thesis, Сумский государственный университет, 2015. http://essuir.sumdu.edu.ua/handle/123456789/40772.

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Оценена эффективность включения гидрофобных наночастиц CdSe/ZnS, покрытых триоктилфосфиноксидом (λmax em= 610 нм) в мембраны липосом, состоящих из следующих липидов: 1,2- дистеароил-sn-глицеро-3-фосфохолин (DSPC), природный фосфатидилхолин (РС), холестерол (СН) и 1,2-дипальмитоилглицеро-3-фосфоэтаноламин-N-[метокси-(полиэтиленгликоль)-2000] (DPPEPEG 2000) в различных молярных соотношениях.
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Jullien, Soizic. "Etude in vitro de l'action de l'antibiotique polyenique amphotericine b sous forme liposomale." Paris 6, 1988. http://www.theses.fr/1988PA066318.

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Mise au point d'un systeme de vectorisation de l'antibiotique polyenique amphotericine afin d'augmenter sa toxicite selective, en nous interessant aux vesicules soniquees unilamellaires. L'utilisation de methodes spectroscopiques a permis de quantifier le taux d'antibiotique fixe aux vesicules dans differentes preparations liposomales
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Sandström, Maria. "Physico-Chemical Investigations of Bilayer Discs and Related Lipid Structures Formed in Liposomal Systems Intended for Triggered Release." Doctoral thesis, Uppsala University, Department of Physical Chemistry, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7606.

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<p>This thesis describes results from fundamental studies of liposomes intended for drug delivery and pH or temperature triggered release. In addition, the effect of lipid composition on bilayer disc formation and a potential application of the bilayer discs were investigated.</p><p>The lower pH encountered by endocytosed liposomes can be utilized to trigger drug release. The mechanisms behind cytosolic drug delivery were investigated using two different kinds of pH-sensitive liposomes. The results indicate that incorporation of non-lamellar forming lipids into the endosome membrane may allow
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Zohair, Abdellah. "Voie classique du système complémentaire : interaction entre C1q, et lipopolysaccharides d'un mutant heptose- d'Escherichia coli K-12." Grenoble 1, 1988. http://www.theses.fr/1988GRE10154.

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Saverot-Dauvergne, Agnès. "Modifications des lipoprotèines de haute densité (HDL) d'origine humaine et de leurs sous-classes (HDL2, HDL3) par des liposomes de phosphatidylcholines et de sphingomyélines : analyse biochimique et étude structurale par résonance paramagnétique électronique (RPE)." Paris 5, 1990. http://www.theses.fr/1990PA05P619.

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Chen, Changfeng. "A Molecular Study of Membrane Structure in Liposomes." Fogler Library, University of Maine, 2009. http://www.library.umaine.edu/theses/pdf/ChenC2009.pdf.

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Books on the topic "Liposome structure"

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Dejesus, Carl, and Lourdes Trask. Chloroplasts and Cytoplasm : Structure and Functions: Life Sciences / Biology / Cell Biology. Nova Science Publishers, Incorporated, 2018.

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Johnsson, Markus. Sterically Stabilised Liposomes and Related Lipid Aggregates: Fundamental Studies on Aggregate Structure and Stability. Uppsala Universitet, 2001.

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Silvander, Mats. Structure and Stability of Liposomes: Interactions With Micelle-Forming Surfactants (Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, 455). Uppsala Universitet, 1999.

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Book chapters on the topic "Liposome structure"

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Bouwstra, J. A., H. E. J. Hofland, F. Spies, G. S. Gooris, and H. E. Junginger. "Changes in the Structure of the Human Stratum Corneum Induced by Liposomes." In Liposome Dermatics. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-48391-2_13.

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Stoeber, Miriam. "Liposome Binding Assay to Characterize the Structure and Function of Cavin Proteins." In Methods in Molecular Biology. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0732-9_12.

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Oellerich, Silke, Peter Hildebrandt, Sophie Lecomte, Thomas Heimburg, and Maité Paternostre. "Binding of cytochrome c to phospholipid vesicles and the perturbation of the liposome and protein structure." In Spectroscopy of Biological Molecules: New Directions. Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-011-4479-7_168.

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Neekhra, Suditi, Priyanka Maske, and Roshan Keshari. "Liposomes and Lipid Structures." In Nanomaterials in Healthcare. CRC Press, 2023. http://dx.doi.org/10.1201/9781003322368-4.

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Bonaccio, S., C. Cescato, P. Walde, and P. L. Luisi. "Liposomes from Lipidonucleotides and from Lipidopeptides." In Self-Production of Supramolecular Structures. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0754-9_21.

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Zasadzinski, J. A., L. E. Scriven, and H. T. Davis. "Structure of Liposomes by Electron Microscopy." In Surfactants in Solution. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4615-7981-6_15.

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Gregoriadis, Gregory. "Liposomes as Immunological Adjuvants: The Immune Response and the Effect of Liposomal Structural Characteristics." In Biomembranes. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-61374-6_3.

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Mason, Jeffrey T. "Properties of Mixed-Chain-Length Phospholipids and Their Relationship to Bilayer Structure." In Handbook of Nonmedical Applications of Liposomes. CRC Press, 2023. http://dx.doi.org/10.1201/9780429291449-9.

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Gregoriadis, Gregory, Roghieh Saffie, and Stephen L. Hart. "Efficient Incorporation of Plasmid DNA Within Liposomes of Varying Structural Characteristics: Liposomal DNA Integrity and Transfection Efficiency." In Targeting of Drugs 5. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4615-6405-8_15.

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Janoff, A. S. "Liposomes and Lipid Structures as Carriers of Amphotericin B." In Perspectives in Antiinfective Therapy. Vieweg+Teubner Verlag, 1989. http://dx.doi.org/10.1007/978-3-322-86064-4_19.

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Conference papers on the topic "Liposome structure"

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Liu, Y., D. Cheng, G. J. Sonek, and M. W. Berns. "Micro-regional temperature measurements of biological membranes irradiated by optical tweezers." In The European Conference on Lasers and Electro-Optics. Optica Publishing Group, 1994. http://dx.doi.org/10.1364/cleo_europe.1994.cmo1.

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Single-point thermometry, or the measurement of localized temperature changes, is a key technique for characterizing the physical, chemical, and biological process at a specific biological site, especially for a medium that can be heated up by a highly focused laser beam. Herein, we report on the development of a technique for the nondestructive local temperature measurement of optically irradiated biological membranes, based on fluorescence from an environmentally sensitive dye1 in an organically engineered liposome.2 An optical multichannel analyzer (OMA) is combined with a microscope to mea
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Zhang, Z., T. Akai, M. Sohgawa, K. Takada, K. Yamashita, and M. Noda. "Bioassay of Target Proteins Using A NiCr Strain Gauge-Cantilever Liposome Biosensor with Droplet-Sealed Structure." In 2014 International Conference on Solid State Devices and Materials. The Japan Society of Applied Physics, 2014. http://dx.doi.org/10.7567/ssdm.2014.ps-11-16.

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Zhang, Ying, and Philip R. LeDuc. "Understanding Biological Structures Through Exploring the Mechanical Response of Cell-Like Systems." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192679.

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The actin cytoskeleton provides mechanical support for the cell and influences activities such as cancer metastasis and chemotaxis. While their mechanical responses have been studied in vivo and in vitro, understanding the link between these two forms remains challenging. To explore this gap and further understand cell structure, we reconstructed the cell cytoskeleton in a membrane-like spherical liposome to mimic the cellular environment; this enables an artificial “cell like” system. Through this approach, we are pursuing a path to compare in vitro mechanics from a polymer physics perspectiv
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González-Amezcua, O. "Structural Thermodynamics of Cationic Liposome DNA System." In ADVANCED SUMMER SCHOOL IN PHYSICS 2005: Frontiers in Contemporary Physics EAV05. AIP, 2006. http://dx.doi.org/10.1063/1.2160991.

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Inoue, K., K. Kamiya, T. Osaki, N. Miki, and S. Takeuchi. "Non-spherical liposome formation using 3D-laser-printed micro-cube structures." In 2016 IEEE 29th International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2016. http://dx.doi.org/10.1109/memsys.2016.7421592.

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Di Maio, Isabelle L., Daniel Carl, Patrik Langehanenberg, et al. "Structural properties of liposomes from digital holographic microscopy." In Microelectronics, MEMS, and Nanotechnology, edited by Dan V. Nicolau. SPIE, 2005. http://dx.doi.org/10.1117/12.638823.

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Barton, Scott. "Exploring lipid structure and phases with x-ray scattering." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/hsds8310.

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X-ray scattering and specifically Small Angle X-ray Scattering (SAXS) is a primary tool for the identification of phases and hierarchical structural arrangement of lipids over exponential length scales, from angstroms to microns. In this talk, we will present a heuristic view of x-ray scattering to understand the nature of the measurement and how a researcher can: 1) Extract and monitor critical molecular dimensions in complex assemblies, and 2) Define and characterize building blocks of molecular components at different length scales in the same sample. Â Recent and motivating examples from F
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Matviykiv, Sofiya, Marzia Buscema, Tamás Mészáros, et al. "Liposomes: bio-inspired nano-containers for physically triggered targeted drug delivery." In SPIE Smart Structures and Materials + Nondestructive Evaluation and Health Monitoring, edited by Mato Knez, Akhlesh Lakhtakia, and Raúl J. Martín-Palma. SPIE, 2017. http://dx.doi.org/10.1117/12.2258378.

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Kornilov, F. D., E. A. Ananiev, E. V. Vasilieva, K. S. Mineev, S. A. Goncharuk, and M. V. Goncharuk. "CO-TRANSLATIONAL FOLDING OF MEMBRANE PROTEINS DURING CELL FREE SYNTHESIS." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-337.

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The biochemical obtaining of natively folded membrane proteins (MPs) is an extremely important task of modern structural biology. We have studied the efficiency of co-translational incorporation of MPs into various membrane-mimicking media — liposomes, micelles, and bicelles during the cell-free synthesis. The retinal protein of Exiguobacterium sibiricum (ESR) was chosen as an object of study.
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Chaves, Matheus Andrade, and Samantha Cristina Pinho. "Effect of phospholipid composition on the structure and physicochemical stability of proliposomes incorporating curcumin and cholecalciferol." In 21st International Drying Symposium. Universitat Politècnica València, 2018. http://dx.doi.org/10.4995/ids2018.2018.7357.

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Proliposomes are dry phospholipid-based particles in which bioactives can be entrapped, and that can produce liposomal suspensions if adequately hydrated. In our study, curcumin and cholecalciferol were incorporated in proliposomes obtained by coating of micronized sucrose. Different mass ratios of Lipoid S40 and Phospholipon 90H were used to produce the proliposomes. The powders were structurally characterized and bioactives content were analyzed over 60 days of storage. Curcumin and cholecalciferol amounts in F100CV formulation were 100 and 98.7% of their initial amount, respectively. Strucu
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Reports on the topic "Liposome structure"

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Altman, Rebecca, Geraldine Richmond, Emma Tran, et al. MOLECULAR STRUCTURE, BONDING AND ASSEMBLY AT NANOEMULSION AND LIPOSOME SURFACES. Office of Scientific and Technical Information (OSTI), 2019. http://dx.doi.org/10.2172/2246651.

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Montville, Thomas J., and Roni Shapira. Molecular Engineering of Pediocin A to Establish Structure/Function Relationships for Mechanistic Control of Foodborne Pathogens. United States Department of Agriculture, 1993. http://dx.doi.org/10.32747/1993.7568088.bard.

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This project relates the structure of the bacteriocin molecule (which is genetically determined) to its antimicrobial function. We have sequenced the 19,542 bp pediocin plasmid pMD136 and developed a genetic transfer system for pediococci. The pediocin A operon is complex, containing putative structural, immunity, processing, and transport genes. The deduced sequence of the pediocin A molecule contains 44 amino acids and has a predicted PI of 9.45. Mechanistic studies compared the interaction of pediocin PA-1 and nisin with Listeria monocytgenes cells and model lipid systems. While significant
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Kanner, Joseph, Edwin Frankel, Stella Harel, and Bruce German. Grapes, Wines and By-products as Potential Sources of Antioxidants. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7568767.bard.

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Several grape varieties and red wines were found to contain large concentration of phenolic compounds which work as antioxidant in-vitro and in-vivo. Wastes from wine production contain antioxidants in large amounts, between 2-6% on dry material basis. Red wines but also white wines were found to prevent lipid peroxidation of turkey muscle tissues stored at 5oC. The antioxidant reaction of flavonoids found in red wines against lipid peroxidation were found to depend on the structure of the molecule. Red wine flavonoids containing an orthodihydroxy structure around the B ring were found highly
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Choudhary, Ruplal, Victor Rodov, Punit Kohli, Elena Poverenov, John Haddock, and Moshe Shemesh. Antimicrobial functionalized nanoparticles for enhancing food safety and quality. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7598156.bard.

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Original objectives The general goal of the project was to utilize the bactericidal potential of curcumin- functionalizednanostructures (CFN) for reinforcement of food safety by developing active antimicrobial food-contact surfaces. In order to reach the goal, the following secondary tasks were pursued: (a) further enhancement of the CFN activity based on understanding their mode of action; (b) preparing efficient antimicrobial surfaces, investigating and optimizing their performance; (c) testing the efficacy of the antimicrobial surfaces in real food trials. Background to the topic The projec
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