Academic literature on the topic 'Microbicidal'

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Journal articles on the topic "Microbicidal"

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Hossain, Mohammad M., and Michael A. Parniak. "In Vitro Microbicidal Activity of the Nonnucleoside Reverse Transcriptase Inhibitor (NNRTI) UC781 against NNRTI-Resistant Human Immunodeficiency Virus Type 1." Journal of Virology 80, no. 9 (2006): 4440–46. http://dx.doi.org/10.1128/jvi.80.9.4440-4446.2006.

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ABSTRACT The nonnucleoside reverse transcriptase inhibitor (NNRTI) UC781 is under development as a microbicide to prevent sexual transmission of the human immunodeficiency virus type 1 (HIV-1). However, NNRTI-resistant HIV-1 is increasingly prevalent in the infected population, and one of the concerns for NNRTI-based microbicides is that they will be ineffective against drug-resistant virus and may in fact selectively transmit NNRTI-resistant virus. We evaluated the microbicidal activity of UC781 against UC781-resistant (UCR), efavirenz-resistant (EFVR), and nevirapine-resistant (NVPR) strains
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Knapp, Laura, Alejandro Amézquita, Peter McClure, Sara Stewart, and Jean-Yves Maillard. "Development of a Protocol for Predicting Bacterial Resistance to Microbicides." Applied and Environmental Microbiology 81, no. 8 (2015): 2652–59. http://dx.doi.org/10.1128/aem.03843-14.

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ABSTRACTRegulations dealing with microbicides in Europe and the United States are evolving and now require data on the risk of the development of resistance in organisms targeted by microbicidal products. There is no standard protocol to assess the risk of the development of resistance to microbicidal formulations. This study aimed to validate the use of changes in microbicide and antibiotic susceptibility as initial markers for predicting microbicide resistance and cross-resistance to antibiotics. Three industrial isolates (Pseudomonas aeruginosa,Burkholderia cepacia, andKlebsiella pneumoniae
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Gupta, Gopal. "Microbicidal spermicide or spermicidal microbicide?" European Journal of Contraception & Reproductive Health Care 10, no. 4 (2005): 212–18. http://dx.doi.org/10.1080/13625180500280753.

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Zairi, Amira, Frédéric Tangy, Khaireddine Bouassida, and Khaled Hani. "Dermaseptins and Magainins: Antimicrobial Peptides from Frogs' Skin—New Sources for a Promising Spermicides Microbicides—A Mini Review." Journal of Biomedicine and Biotechnology 2009 (2009): 1–8. http://dx.doi.org/10.1155/2009/452567.

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Sexually transmitted infections (STIs) and human immunodeficiency virus (HIV), the causative agents of acquired immunodeficiency syndrome (AIDS), are two great concerns in the reproductive health of women. Thus, the challenge is to find products with a double activity, on the one hand having antimicrobial/antiviral properties with a role in the reduction of STI, and on the other hand having spermicidal action to be used as a contraceptive. In the absence of an effective microbicide along with the disadvantages of the most commonly used spermicidal contraceptive worldwide, nonoxynol-9, new emph
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Maillard, Jean-Yves. "Emergence of bacterial resistance to microbicides and antibiotics." Microbiology Australia 31, no. 4 (2010): 159. http://dx.doi.org/10.1071/ma10159.

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Public awareness of the role of microorganisms in infection and spoilage and the role of the media in highlighting poor hygiene and the failure of healthcare settings in preventing hospital-acquired infections, have fuelled the use of products containing one or several microbicides in the healthcare environment but also at home. The number of such products with a microbicidal claim is increasing rapidly, although their impact on the microbial flora, notably in terms of emerging antimicrobial resistance has not been documented. With increasing evidence that microbicides can lead to bacterial re
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Watson, Karen M., Christa E. Buckheit, and Robert W. Buckheit. "Comparative Evaluation of Virus Transmission Inhibition by Dual-Acting Pyrimidinedione Microbicides Using the Microbicide Transmission and Sterilization Assay." Antimicrobial Agents and Chemotherapy 52, no. 8 (2008): 2787–96. http://dx.doi.org/10.1128/aac.01657-07.

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ABSTRACT In the absence of a fully effective human immunodeficiency virus (HIV) vaccine, topical microbicides represent an important strategy for preventing the transmission of HIV through sexual intercourse, the predominant mode of HIV transmission worldwide. Although a comprehensive understanding of HIV transmission has not yet emerged in the microbicide field, it is likely the result of rapid infection of monocyte-derived cells in the vaginal mucosa by CCR5-tropic viruses. Inhibition of HIV transmission requires agents that prevent entry, fusion, reverse transcription, or other preintegrati
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Veazey, Ronald S., Udayan Chatterji, Michael Bobardt, et al. "C5A Protects Macaques from Vaginal Simian-Human Immunodeficiency Virus Challenge." Antimicrobial Agents and Chemotherapy 60, no. 1 (2015): 693–98. http://dx.doi.org/10.1128/aac.01925-15.

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ABSTRACTA safe and effective vaginal microbicide could decrease human immunodeficiency virus (HIV) transmission in women. Here, we evaluated the safety and microbicidal efficacy of a short amphipathic peptide, C5A, in a rhesus macaque model. We found that a vaginal application of C5A protects 89% of the macaques from a simian-human immunodeficiency virus (SHIV-162P3) challenge. We observed no signs of lesions or inflammation in animals vaginally treated with repeated C5A applications. With its noncellular cytotoxic activity and rare mechanism of action, C5A represents an attractive microbicida
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Nims, Raymond W., and M. Khalid Ijaz. "Virucidal Approaches for Hemorrhagic Fever Viruses." Viruses 17, no. 5 (2025): 663. https://doi.org/10.3390/v17050663.

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We have reviewed the primary literature on the virucidal efficacy of microbicidal active ingredients, formulated microbicides, and physical inactivation approaches (heat, irradiation) for hemorrhagic fever viruses (HFVs) (arenaviruses, filoviruses, flaviviruses, hantaviruses, nairoviruses, and phenuiviruses), and for two non-typical HFV paramyxoviruses. As each of these HFVs are large, lipid-enveloped RNA viruses, their susceptibilities to virucidal agents are informed by the so-called hierarchy of susceptibility of pathogens to microbicides. The unique susceptibility of lipid-enveloped viruse
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Krebs, Fred C., Shendra R. Miller, Bradley J. Catalone, et al. "Comparative In Vitro Sensitivities of Human Immune Cell Lines, Vaginal and Cervical Epithelial Cell Lines, and Primary Cells to Candidate Microbicides Nonoxynol 9, C31G, and Sodium Dodecyl Sulfate." Antimicrobial Agents and Chemotherapy 46, no. 7 (2002): 2292–98. http://dx.doi.org/10.1128/aac.46.7.2292-2298.2002.

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ABSTRACT In experiments to assess the in vitro impact of the candidate microbicides nonoxynol 9 (N-9), C31G, and sodium dodecyl sulfate (SDS) on human immune and epithelial cell viability, cell lines and primary cell populations of lymphocytic and monocytic origin were generally shown to be equally sensitive to exposures ranging from 10 min to 48 h. However, U-937 cells were more sensitive to N-9 and C31G after 48 h than were primary monocyte-derived macrophages. Cytokine activation of monocytes and lymphocytes had no effect on cell viability following exposure to these microbicidal compounds.
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Springthorpe, V. Susan, and Syed A. Sattar. "Carrier Tests to Assess Microbicidal Activities of Chemical Disinfectants for Use on Medical Devices and Environmental Surfaces." Journal of AOAC INTERNATIONAL 88, no. 1 (2005): 182–201. http://dx.doi.org/10.1093/jaoac/88.1.182.

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Abstract For well over a decade, many deficiencies have been identified in current AOAC methods used to assess the microbicidal activities of chemical disinfectants on medical devices and environmental surfaces. This report discusses the development of quantitative carrier tests (QCT) designed to address these concerns. Decontamination of surfaces with dried inocula is invariably more difficult than when microorganisms are in suspension. For medical device as well as environmental decontamination, microbicides are used on contaminated surfaces, thus making it necessary to evaluate their microb
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Dissertations / Theses on the topic "Microbicidal"

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Allen, Rebecca G. "Macrophage Microbicidal Activity is Enhanced by Stressor-Exposure." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1324960758.

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Hsu, Bryan Boen. "Investigation of microbicidal activity of surface-immobilized hydrophobic polycations." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/62728.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2011.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Hydrophobic polycations have been shown to completely kill bacterial, fungal, and viral pathogens, on-contact. Herein we describe advances with this technology on two fronts: (1) innovation of a polycationic-derivative that simplifies the labor-intensive covalent-immobilization procedure, and (2) elucidation of the current mechanistic understanding of this phenomenon. First, we developed and characterized a novel polycationic polyme
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Curfman, Christopher L. "Micellar properties of spermicidal and microbicidal quaternary ammonium surfactants." Thesis, This resource online, 1996. http://scholar.lib.vt.edu/theses/available/etd-03042009-041158/.

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Gomes, Clayson Moura. "Infecção murina por Leishmania (Viannia) braziliensis: modelo em camundongos deficientes em interferon gama, fagócito oxidase ou óxido nítrico sintase induzida." Universidade Federal de Goiás, 2015. http://repositorio.bc.ufg.br/tede/handle/tede/5489.

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Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2016-04-18T14:57:11Z No. of bitstreams: 2 Tese - Clayson Moura Gomes - 2015.pdf: 2080474 bytes, checksum: e53c02c9eac98545d091fb13331c2b9a (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2016-04-18T14:58:58Z (GMT) No. of bitstreams: 2 Tese - Clayson Moura Gomes - 2015.pdf: 2080474 bytes, checksum: e53c02c9eac98545d091fb13331c2b9a (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Made available in
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Lima, Tatiane Soares de. "Caracterização das ações do veneno de Crotalus durissus terrificus sobre funções de neutrófilos." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/41/41135/tde-21022011-132634/.

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Estudos anteriores demonstraram que o veneno de Crotalus durissus terrificus (VCdt) apresenta ação antiinflamatória prolongada, bem como inibe o espraiamento e a atividade fagocítica de macrófagos peritoneais, sendo a crotoxina (CTX), o principal componente do VCdt, a responsável por esses efeitos. Em relação aos neutrófilos, demonstrou-se que o VCdt inibe, in vitro e in vivo, a fagocitose por essas células, porém o componente do VCdt responsável por esse efeito não foi identificado. Dessa forma, o objetivo desse estudo foi identificar o componente responsável pelo efeito inibitório do VCdt so
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Kilelee, Erin M. "Modeling the interaction of the platelet microbicidal protein tPMP-1 with the cell membrane." View electronic thesis (PDF), 2009. http://dl.uncw.edu/etd/2009-3/r3/kileleee/erinkilelee.pdf.

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Zhang, Jinya. "Unmasking the microbicidal and immunostimulatory properties of warthog fecal microbiota in vitro and in vivo." Doctoral thesis, Universitat Autònoma de Barcelona, 2020. http://hdl.handle.net/10803/670999.

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El virus de la Pesta Porcina Africana (VPPA) és l’amenaça principal per a la indústria porcina. L’absència de vacunes enfront del virus complica el control i erradicació de la malaltia que provoca: la Pesta Porcina Africana (PPA). El VPPA infecta tant a porcs domèstics com a senglars euroasiàtics (ambdós Sus Scrofa), cursant amb diferents quadres clínics, que varien des de la PPA aguda o hiperaguda, amb taxes de mortalitat de fins al 100%, fins a la infecció crònica. Malgrat el VPPA és capaç d’infectar també als porcs salvatges africans, incloent al facoquer, el virus no provoca signes clínics
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Mawela, Kedibone Gloria. "Evaluation of RANTES analogue expression in Nicotiana benthamiana and Lycopersicon esculentum and their topical microbicidal activity." Thesis, University of Pretoria, 2013. http://hdl.handle.net/2263/32946.

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The HIV/AIDS pandemic has dramatically altered patterns of morbidity and mortality in sub-Saharan Africa during the last two decades. In the absence of HIV vaccine, microbicides may offer viable option for protection against HIV infection. Microbicides are products that are applied topically inside the vagina or rectum that act to impede transmission of HIV and other sexually transmitted diseases. Small human chemokines such as RANTES (regulated upon activation, normal T cell expressed and secreted) are currently been investigated as microbicides candidates. A number of N-terminally mod
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Palaniappan, Sevugan. "Ohmic heating of foods : studies on microbicidal effect of electricity, electrical conductivity of foods, and heat transfer in liquid- particle mixtures /." The Ohio State University, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487757723995203.

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Fontoura, Juliana Tolfo da. "Desempenho de microbicidas para preservação de peles e couros." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2013. http://hdl.handle.net/10183/96481.

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Um problema na indústria coureira é a deterioração de peles e couros devido ao desenvolvimento de microrganismos no processamento do couro. As peles e os couros contêm nutrientes adequados para o crescimento de microrganismos, como carboidratos, gorduras e proteínas, além das condições ambientais, alta umidade, temperatura de armazenagem e pH favoráveis. Alguns gêneros de bactérias e fungos sintetizam importantes substâncias deste substrato, causando modificações prejudiciais na superfície do couro e nas propriedades físico-mecânicas, deixando manchas pigmentadas de difícil remoção, afetando a
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Books on the topic "Microbicidal"

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Khodaie, Sasan. Microbicidal effectiveness of ultrasound on some oral root canal bacteria. University of Manchester, 1993.

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Rencher, William F. Vaginal microbicide formulations workshop. Edited by Contraceptive Research and Development Program. International Workshop. Lippincott-Raven, 1998.

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National Institute of Allergy and Infectious Diseases (U.S.), ed. NIAID topical microbicide strategic plan. U.S. Dept. of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases, 2003.

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Paulus, Wilfried. Microbicides for the Protection of Materials. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2118-7.

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Nuttall, Jeremy, ed. Microbicides for Prevention of HIV Infection. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-44596-9.

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Rehman, Suriya, and Ebtesam Al-Suhaimi, eds. Nanotechnology Based Microbicides and Immune Stimulators. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-96-0397-8.

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Council, Population, and International Family Health, eds. The case for microbicides: A global priority. 2nd ed. Population Council, 2001.

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Jennifer, Frost, Darroch Jacqueline E, and Alan Guttmacher Institute, eds. Microbicides: A new defense against sexually transmitted diseases. The Alan Guttmacher Institute, 1999.

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Paulus, Wilfried. Microbicides for the protection of materials: A handbook. Chapman & Hall, 1993.

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Paulus, Wilfried. Microbicides for the Protection of Materials: A Handbook. Springer Netherlands, 1993.

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Book chapters on the topic "Microbicidal"

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Srivastava, Nishant, and Shailendra K. Saxena. "Microbicidal Nanoparticles." In Synthesis and Applications of Nanoparticles. Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-6819-7_17.

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Pinchuk, L. S., V. A. Goldade, A. V. Makarevich, and V. N. Kestelman. "Adsorptive and Microbicidal PFM." In Melt Blowing. Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-642-55984-6_9.

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Al-Adham, Ibrahim, Randa Haddadin, and Phillip Collier. "Types of Microbicidal and Microbistatic Agents." In Russell, Hugo & Ayliffe's. Wiley-Blackwell, 2012. http://dx.doi.org/10.1002/9781118425831.ch2.

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Sheng, Hong, Keisuke Nakamura, Taro Kanno, Keiichi Sasaki, and Yoshimi Niwano. "Microbicidal Activity of Artificially Generated Hydroxyl Radicals." In Interface Oral Health Science 2014. Springer Japan, 2015. http://dx.doi.org/10.1007/978-4-431-55192-8_17.

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Srinivasan, Venkataramanujam, Mahaneem Mohamed, and Hisanori Kato. "Melatonin: Its Microbicidal Properties and Clinical Applications." In Melatonin and Melatonergic Drugs in Clinical Practice. Springer India, 2013. http://dx.doi.org/10.1007/978-81-322-0825-9_5.

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Opal, Steven M., and Richard L. Yap. "Host Microbicidal Actions of the Innate Immune Response." In Immunology and Infectious Disease. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0245-6_1.

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Nielsen, H. "Inflammatory Indices in Chronic Bronchitis. Monocyte-Macrophage Microbicidal Activity." In Inflammatory Indices in Chronic Bronchitis. Birkhäuser Basel, 1990. http://dx.doi.org/10.1007/978-3-0348-7488-5_16.

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Sattar, Syed A., and Sabah Bidawid. "Using Microbicidal Chemicals to Interrupt the Spread of Foodborne Viruses." In Viruses in Foods. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30723-7_14.

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Hurst, James K. "Oxygen-Derived Toxins Generated by Neutrophils and their Microbicidal Mechanisms." In The Activation of Dioxygen and Homogeneous Catalytic Oxidation. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-3000-8_20.

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Marodi, Laszlo, Christopher Tourney, Rita Kaposzta, Richard B. Johnston, and Nicole Moguilevsky. "Acquisition and Use of Myeloperoxidase in the Microbicidal Activity of Macrophages." In The Peroxidase Multigene Family of Enzymes. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-58314-8_9.

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Conference papers on the topic "Microbicidal"

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Kikuchi, Yasushi, Kenji Tohmoto, Masayoshi Ozawa, Tsuyoshi Kanamaru, and Takeshi Sakane. "Microbiologically Influenced Corrosion of Copper in Ground Water." In CORROSION 1999. NACE International, 1999. https://doi.org/10.5006/c1999-99170.

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Abstract Microbiologically Influenced Corrosion (MIC) was suspected in the corrosion failure of heat exchanger copper piping, carrying groundwater. Laboratory simulation studies were planned to find out the mechanism of corrosion. Ground water from the same plant was transferred to the laboratory aseptically and used for the experiment. Bacteria in the test solution were activated by the addition of low concentration of nutrients. Both welded and non welded Cu samples were exposed to the test solution. After 2 weeks, a lot of corrosion sites were observed on the surface in the form of pitting.
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Wiencek, K. Mark, and John S. Chapman. "Water Treatment Biocides: How Do They Work and Why Should You Care?" In CORROSION 1999. NACE International, 1999. https://doi.org/10.5006/c1999-99308.

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Abstract A variety of different microbicides employing different mechanisms of action (MOA) are used to control microbial growth in cooling water systems. Although dosing strategies are often based on the target organisms and their behavior within the system, targets within the microbes can be equally important for designing and optimizing an effective treatment program. In addition, an understanding of the mechanisms of the microbicides can often provide insight into the proper use of the microbicides, and can be a useful tool in troubleshooting problems. Cooling water microbicides can be cla
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Zisson, Peter S., and Dick Youmans. "Qualifying New Chemistries for Reverse Osmosis Membrane Treatment." In CORROSION 2000. NACE International, 2000. https://doi.org/10.5006/c2000-00319.

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Abstract The use of reverse osmosis for water purification is increasing. Reverse osmosis offers an economically viable approach for the removal of dissolved solids from water. One aspect of membrane use is the need to treat the incoming water to prevent scale, microbiological growth and fouling from inhibiting the membrane's ability to function. In extreme conditions, these conditions can ruin a membrane, forcing expensive replacement. Treatment is itself of no value if the treatment chemicals are antagonistic to the membrane. It is of no benefit to feed a microbicide to a reverse osmosis sys
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Maxwell, S., G. MacKenzie, C. Kuijvenhoven, B. Lomans, and T. Granli. "Laboratory Studies of Microbicide and Nitrate Strategies for MIC and Reservoir Souring Mitigation." In CORROSION 2008. NACE International, 2008. https://doi.org/10.5006/c2008-08663.

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Abstract Microbicide and nitrate are applied, either alone or in combination, in many seawater injection systems as controls to mitigate microbiologically influenced corrosion (MIC) or reservoir souring or both. Dosing strategies vary widely from field to field. In some fields this may be due to physicochemical conditions within the injection facilities and reservoir that dictate which chemical formulations can be applied. In others, the strategy might be selected and optimised based on which of the problems, MIC or souring, is assessed as the most important in terms of flow assurance. In a fe
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Tully, J. C., G. G. Engstrom, L. M. Kye, and K. Rimmer. "Monitoring and Controlling Gaseous Chlorine Alternatives in Open Recirculating Systems." In CORROSION 1993. NACE International, 1993. https://doi.org/10.5006/c1993-93476.

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Abstract Effective microbiological control can be achieved by monitoring microbial levels as well as actual microbicide treatment levels. The key to measuring the effectiveness of any biocide program, whether it be oxidizing or non-oxidizing, is the ability to quickly and accurately measure the microbiological activity in a given cooling system. Traditional techniques such as plate counts and more recently dipslides are commonly used for this purpose. The incubation period associated with these procedures, usually between 24 - 72 hours, is sufficient to allow a significant increase in biofouli
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Karri, Sunil, and Sarah L. Kieweg. "Mathematical Simulation and Parametric Study of Flow of a Microbicidal Gel Between Elastic Boundaries." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53719.

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Topical microbicides, the next generation prevention tool for HIV and other sexually transmitted pathogens, hold great promise if the target vaginal or rectal epithelium is coated effectively. A microbicide consists of an active ingredient within a polymeric delivery vehicle (e.g. polymeric liquid or ‘gel’). Most research in the field of microbicides has been limited to the development of an active ingredient and many microbicidal trails have failed in the past. Thus, there is a need to design a delivery vehicle that optimizes the efficacy of a microbicidal agent. The effectiveness of the gel
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Talbi, Zouhair, and Sarah L. Kieweg. "The Impact of Tissue Viscoelasticity on the Flow Dynamics of an Anti-HIV Microbicidal Gel: Numerical Simulations." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14116.

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Coating vaginal or rectal epithelium using microbicidal gels is a promising preventive procedure against HIV and other sexually transmitted infections (STIs). A microbicidal gel is deployed as a delivery vehicle of anti-HIV and other anti-STI agents and it is also used to act as barrier between the pathogens and the biological tissue. The efficacy of a microbicidal gel depends greatly on the extent of the spreading and the amount of the epithelial surfaces covered.
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Kheyfets, Vitaly O., and Sarah L. Kieweg. "Free Surface Coating Flows of Non-Newtonian Gels: 3-D Numerical Simulation of Gravity-Induced Flow." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176696.

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Developing a mechanism capable of protecting the vaginal or rectal epithelium from sexually transmitted pathogens can be an effective tool in the prevention of HIV infection [1]. One such tool can come in the form of a microbicide gel, used to provide a physical barrier and act as a delivery vehicle for its active ingredient [1]. In order for the microbicide to be an effective barrier and delivery vehicle it must have the capability to coat the epithelium for a specific amount of time and sustain its structural integrity under the influence of gravity and other perturbation forces. In addition
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Kheyfets, Vitaly O., and Sarah L. Kieweg. "Instrument and Method for Visualizing and Characterizing Gravity-Induced Flow of Gels in an Environment Simulating Aspects of the Vaginal Lumen." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-193062.

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Developing a mechanism capable of protecting the vaginal or rectal epithelium from sexually transmitted pathogens can be an effective tool in the prevention of HIV infection [1]. One such tool can come in the form of a microbicide gel, which provides a physical barrier and acts as a delivery vehicle for its active ingredient [1]. In order for the microbicide to be an effective barrier and delivery vehicle, it must have the capability to coat the epithelium for a specific amount of time and sustain its structural integrity under the influence of gravity and other perturbation forces. In additio
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Bonnett, Raymond, Roger L. Evans, and Aslam B. B. Galia. "Immobilized photosensitizers: photosensitizer films with microbicidal effects." In BiOS Europe '97, edited by Kristian Berg, Benjamin Ehrenberg, Zvi Malik, Johan Moan, and Abraham Katzir. SPIE, 1997. http://dx.doi.org/10.1117/12.297788.

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Reports on the topic "Microbicidal"

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Cardellina, John. Grapefruit Seed Extract Laboratory Guidance Document. ABC-AHP-NCNPR Botanical Adulterants Prevention Program, 2017. http://dx.doi.org/10.59520/bapp.lgd/avdd8179.

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The case of synthetic microbicides marketed as grapefruit seed extract (GFSE) differs from the other botanicals addressed thus far by the Botanical Adulterants Prevention Program (BAPP) in that the adulteration does not consist of substitution by or inclusion of other botanicals, but rather the inclusion of one or more synthetic microbicidal compounds (disinfectants) in the products. This Laboratory Guidance Document presents a review of the analytical technologies used to differentiate and identify the various microbicides that have been reported from commercial GFSE products, as well as meth
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Selsted, Michael E. Structure and Design of Multipotent Peptide Microbicides. Defense Technical Information Center, 1988. http://dx.doi.org/10.21236/ada199085.

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Attawell, Kathy. The case for microbicides: A global priority. Population Council, 2001. http://dx.doi.org/10.31899/hiv3.1000.

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Brady, Martha, and Elizabeth McGrory. Day of dialogue—Insights and evidence from product introduction: Lessons for microbicides. Population Council, 2007. http://dx.doi.org/10.31899/hiv1.1020.

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Elias, Christopher J., and Lori L. Heise. The development of microbicides: A new method of HIV prevention for women. Population Council, 1993. http://dx.doi.org/10.31899/hiv1993.1001.

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A critical review of current epidemiological trends and social science research demonstrates that there is an urgent need for expanding the range of female-controlled HIV prevention methods. Existing efforts to control the spread of HIV infection primarily through the encouragement of a reduction in the number of sexual partners, widespread condom promotion, and the control of other sexually transmitted infections are inadequate for many of the world's women. Underlying gender power inequities severely limit the ability of many women to protect themselves from HIV infection, especially in the
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Braunstein, Sarah, and Janneke van de Wijgert. Cultural norms and behavior regarding vaginal lubrication during sex: Implications for the acceptability of vaginal microbicides for the prevention of HIV/STIs. Population Council, 2003. http://dx.doi.org/10.31899/rh5.1003.

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Brady, Martha, Saiqa Mullick, Barbara Friedland, Marlena Plagianos, Linda Du Plessis, and Thabiso Mango. Learning from women about HIV risk, HIV testing behaviors, and prevention practices in Mpumalanga, South Africa: A descriptive study to inform microbicides introduction. Population Council, 2015. http://dx.doi.org/10.31899/hiv8.1004.

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Paving the Path: Preparing for Microbicide Introduction—Report of a Qualitative Study in South Africa. Population Council, 2004. http://dx.doi.org/10.31899/hiv15.1011.

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With recently accelerated support for the development of microbicides to prevent HIV transmission and the urgency of the global AIDS epidemic, it is important to begin to identify strategies for introducing a microbicide once it is proven safe and effective and is approved for use. This report presents results from a qualitative study that explored a range of issues likely to influence microbicide introduction—positively or negatively—at three levels: community, health service, and policy. The study, which identified critical issues to be addressed in building support for microbicides and faci
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Paving the Path: Preparing for Microbicide Introduction—Report of a Qualitative Study in South Africa [Executive Summary]. Population Council, 2004. http://dx.doi.org/10.31899/hiv15.1010.

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With recently accelerated support for the development of microbicides to prevent HIV transmission and the urgency of the global AIDS epidemic, it is important to begin to identify strategies for introducing a microbicide once it is proven safe and effective and is approved for use. This executive summary presents results from a qualitative study that explored a range of issues likely to influence microbicide introduction at the community, health service, and policy levels. The study, which identified critical issues to be addressed in building support for microbicides and facilitating a smooth
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