Academic literature on the topic 'Neurological outcomes'

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Journal articles on the topic "Neurological outcomes"

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Anwar, Muhammad Usman, Nabeel Choudhary, Talha Abbas, Rida Zahid, Adeel-Ur Rehman, and Mohammad Faheem Shaikh. "Management of Tethered Cord Syndrome; Our Experience at FJMU/SGRH." Pakistan Journal of Medical & Health Sciences 17, no. 12 (2023): 374–76. https://doi.org/10.53350/pjmhs020231712374.

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Background: Tethered cord syndrome (TCS) is a neurologic condition characterized by abnormal traction of the spinal cord, leading to progressive neurological, urological, and orthopedic deficits. Objective: To evaluate the clinical presentation, operative management, and postoperative outcomes of patients undergoing surgical treatment for tethered cord syndrome at a tertiary neurosurgical center. Methods: A retrospective case series was conducted at the Department of Neurosurgery, Sir Ganga Ram Hospital/Fatima Jinnah Medical University, Lahore, from June 2019 to December 2021. Ten patients (3
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Hong, SungMin, Ji Hoon Jang, Jeong Hoon Yang, Yang Hyun Cho, Joonghyun Ahn, and Jeong-Am Ryu. "Optimal Arterial Blood Gas Tensions for the Prognosis of Favorable Neurological Outcomes in Survivors after Extracorporeal Cardiopulmonary Resuscitation." Journal of Clinical Medicine 11, no. 14 (2022): 4211. http://dx.doi.org/10.3390/jcm11144211.

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Our aim is to assess the optimal levels of oxygen and carbon dioxide for the prognosis of favorable neurologic outcomes in survivors after extracorporeal cardiopulmonary resuscitation (ECPR). We obtained the mean levels of PaCO2 and PaO2 in arterial blood gas samples 72 h after ECPR. The primary outcome was the neurological status, according to the Cerebral Performance Categories (CPC) scale, upon discharge. Of 119 (48.6%) survivors, 95 (38.8%) had favorable neurologic outcomes (CPC 1 or 2). There was a U-shaped relationship between mean arterial blood gas tensions and poor neurological outcom
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Lee, Yun Im, Ryoung-Eun Ko, Joonghyun Ahn, Keumhee C. Carriere, and Jeong-Am Ryu. "Association between Neurologic Outcomes and Changes of Muscle Mass Measured by Brain Computed Tomography in Neurocritically Ill Patients." Journal of Clinical Medicine 11, no. 1 (2021): 90. http://dx.doi.org/10.3390/jcm11010090.

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This study aimed to investigate whether skeletal muscle mass estimated via brain computed tomography (CT) could predict neurological outcomes in neurocritically ill patients. This is a retrospective, single-center study. Adult patients admitted to the neurosurgical intensive care unit (ICU) from January 2010 to September 2019 were eligible. Cross-sectional areas of paravertebral muscles at the first cervical vertebra level (C1-CSA) and temporalis muscle thickness (TMT) on brain CT were measured to evaluate skeletal muscle mass. The primary outcome was the Glasgow Outcome Scale score at 3 month
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Lee, Yun Im, Ryoung-Eun Ko, Jeong Hoon Yang, Yang Hyun Cho, Joonghyun Ahn, and Jeong-Am Ryu. "Optimal Mean Arterial Pressure for Favorable Neurological Outcomes in Survivors after Extracorporeal Cardiopulmonary Resuscitation." Journal of Clinical Medicine 11, no. 2 (2022): 290. http://dx.doi.org/10.3390/jcm11020290.

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We evaluated the optimal mean arterial pressure (MAP) for favorable neurological outcomes in patients who underwent extracorporeal cardiopulmonary resuscitation (ECPR). Adult patients who underwent ECPR were included. The average MAP was obtained during 6, 12, 24, 48, 72, and 96 h after cardiac arrest, respectively. Primary outcome was neurological status upon discharge, as assessed by the Cerebral Performance Categories (CPC) scale (range from 1 to 5). Overall, patients with favorable neurological outcomes (CPC 1 or 2) tended to have a higher average MAP than those with poor neurological outc
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Zhou, Peisen, Huaqing Xu, Bingccan Li, et al. "Neurological outcomes in adult drowning patients in China." Annals of Saudi Medicine 42, no. 2 (2022): 127–38. http://dx.doi.org/10.5144/0256-4947.2022.127.

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BACKGROUND: Drowning is the third leading cause of unintentional death worldwide. The epidemiological characteristics of adult drownings are rarely reported. OBJECTIVE: Investigate factors associated with neurological prognosis in adult drowning inpatients. DESIGN: Multicenter medical record review. SETTING: Tertiary health care institutions. PATIENTS AND METHODS: We collected demographic and clinical data on patients who drowned but survived between September 2006 and January 2020. Neurological prognosis was compared in patients with and without cardiac arrest. MAIN OUTCOME MEASURES: Neurolog
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DeBoer, SL. "Neurological outcomes after near-drowning." Critical Care Nurse 17, no. 4 (1997): 19–25. http://dx.doi.org/10.4037/ccn1997.17.4.19.

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Fawke, Joe. "Neurological outcomes following preterm birth." Seminars in Fetal and Neonatal Medicine 12, no. 5 (2007): 374–82. http://dx.doi.org/10.1016/j.siny.2007.06.002.

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Yu, Qiong, Jiangtao Qi, and Yingwei Wang. "Intraoperative hypotension and neurological outcomes." Current Opinion in Anaesthesiology 33, no. 5 (2020): 646–50. http://dx.doi.org/10.1097/aco.0000000000000904.

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Sarris, Christina E., Krystal L. Tomei, Peter W. Carmel, and Chirag D. Gandhi. "Lipomyelomeningocele: pathology, treatment, and outcomes." Neurosurgical Focus 33, no. 4 (2012): E3. http://dx.doi.org/10.3171/2012.7.focus12224.

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Lipomyelomeningocele represents a rare but complex neurological disorder that may present with neurological deterioration secondary to an inherent tethered spinal cord. Radiological testing is beneficial in determining the morphology of the malformation. Specialized testing such as urodynamic studies and neurophysiological testing may be beneficial in assessing for neurological dysfunction secondary to the lipomyelomeningocele. Early surgical intervention may be beneficial in preventing further neurological decline.
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Jamali, Muhammad Ali, Sania ., Bushra Begum ,. Ramejo, Awais Bashir Larik, Shazia ., and Muhammad Munawer Ali Shaikh. "Peripartum Neurological Injuries and its Outcomes." Pakistan Journal of Medical and Health Sciences 17, no. 9 (2023): 18–21. http://dx.doi.org/10.53350/pjmhs202317918.

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Aim: To study the peri-partum neurological injury and its outcomes. Study Design: Cross sectional study Place and duration of study: Department of Neurosurgery & Department of Obstetrics & Gynaecology, Peoples Medical University Hospital, Nawabshah from 1st July 2022 to 30th June 2023. Methodology: Two hundred and fifty women having a high risk of neurological disorders were included. A high-risk pregnancy was defined with the one having increased threat to fetal morbidity as well as risk of disability presented through clinical symptoms of each case. Biochemical analysis using 5cc blo
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Dissertations / Theses on the topic "Neurological outcomes"

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Starks, Sarah Elizabeth. "Neurological outcomes among pesticide applicators." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/889.

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The acute nervous system toxicity of organophosphate (OP) pesticides is well described. However, the reported long-term effects of OP pesticides on the nervous system are inconsistent. This inconsistency may be due to imprecise estimates of pesticide exposure, variability of central nervous system (CNS) and peripheral nervous system (PNS) assessment, small samples, and poor control of confounding. The primary goal of this research was to examine the association between long-term OP pesticide use on CNS and PNS function among pesticide applicators. An additional goal was to examine the associat
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Kramer, John L. K. "Neurological outcomes after cervical spinal cord injury." Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/37312.

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In addition to overcoming biological barriers that limit regeneration and repair in the central nervous system after spinal cord injury, clinicians and researchers are faced with the daunting task of assessing the safety and efficacy of therapeutics proposed to ameliorate neurological deficits in humans. While the selection of an appropriate clinical endpoint will depend on a number of factors, including the phase of study and the underlying biological activity, the estimated effect size based on preclinical studies in animal models of spinal cord injury of most therapeutics are expectedly sma
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Calinescu, Catalin. "Outcomes of educational intervention with students with neurological disorders." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0014/MQ29148.pdf.

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Harmon, Heidi. "Transient Neurological Abnormalities: Early School Outcomes in Extremely Premature Infants." Case Western Reserve University School of Graduate Studies / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=case1396475321.

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Pujar, S. "The status epilepticus in childhood outcomes study (STEPSOUT) : long-term mortality, neurological, cognitive and neuroimaging outcomes." Thesis, University College London (University of London), 2016. http://discovery.ucl.ac.uk/1485753/.

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Childhood convulsive status epilepticus (CSE) is associated with considerable short-term mortality and morbidity, but data on long-term outcomes are uncertain. In addition, while the current evidence suggests that prolonged febrile seizures (PFS) can result in acute hippocampal injury, whether this evolves into mesial temporal sclerosis (MTS) and cause temporal lobe epilepsy (TLE) in the long-term is uncertain. In the status epilepticus in childhood outcomes study (STEPSOUT), prospective follow-up of a previously identified unique population-based cohort was performed to investigate mortality,
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Talbot, Josephine. "Neurological and cognitive symptoms and wellbeing outcomes in adults with coeliac disease." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8571/.

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The first chapter is a systematic literature review examining what the evidence is for neurological and cognitive symptoms of coeliac disease and non-coeliac gluten sensitivity in adults. The second presents a piece of research investigating whether illness perceptions are moderated and mediated through self-efficacy for the gluten free diet and coping for the outcomes of psychological wellbeing and quality of life. The final chapter is a brief public dissemination document that provides an overview of this thesis.
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Cragg, Jacquelyn Judith. "Secondary complications of spinal cord injury : risk, inter-relationships, and effects on neurological outcomes." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/54076.

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Background: Although there have been major advances in acute care following spinal cord injury (SCI), individuals surviving the acute period experience a reduced life expectancy. Historically, acute respiratory and renal dysfunction were the most prevalent complications, and remain important contributors to mortality. However, all-cause cardiovascular disease (CVD) has now emerged as the leading cause of mortality in chronic SCI. Although it has been long speculated that individuals with SCI may be at a higher risk of complications such as CVD, quantitative data are currently limited. Furtherm
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Kwan, Cheung Keith A. "Monitoring of cannabinoid-based medicines for the treatment of neurological disorders to improve clinical outcomes in minors." Thesis, Queensland University of Technology, 2022. https://eprints.qut.edu.au/228475/1/Keith_Kwan%20Cheung_Thesis.pdf.

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The exact interactions between the endocannabinoid system (ECS) and cannabinoids are still ill-defined, and could lead to more effective treatment if better understood. This project investigated the use of liquid chromatography tandem mass spectrometry (LC-MS/MS) in the measurement of potential biomarkers of cannabinoid and ECS metabolism. Measurement of eicosanoids in human saliva by LC-MS/MS was comparable to their plasma measurement. Cannabidiol (CBD) and CBD metabolites were successfully measured in plasma and saliva.
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Wallin, Ewa. "Post Cardiac Arrest Care : Evaluation of prognostic tools, Patient outcomes and Relatives’ experiences at 6 months after the event." Doctoral thesis, Uppsala universitet, Anestesiologi och intensivvård, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-248044.

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The overall aim of the present thesis was to study post-resuscitation care of cardiac arrest (CA) patients treated with target temperature management 33°C with a focus on evaluation of two prognostic tools: variations in cerebral venous saturation and acute magnetic resonance imaging (MRI) findings on the brain post-CA. An additional aim was to investigate patients’ neurological outcome and relatives’ experiences 6 months after the event. Paper I describes the cerebral oxygen saturation of blood obtained from a jugular bulb (SjvO2) catheter The results showed that patients with poor outcome te
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Chughtai, Talat S. "Absence of an elective on-site neurological service : impact on outcomes in severely injured head trauma patients in a tertiary referral trauma center." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97932.

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A retrospective study was conducted to compare two groups of patients treated at the Montreal General Hospital (MGH) for traumatic brain injuries (TBI). The time to neurosurgery, vital status and length of stay in the ICU was evaluated in 299 patients treated before (1997-1998), and 307 patients after (2000-2001) an elective neurosurgery service was eliminated from the NIGH. The outcomes were not significantly different between the two groups. There were trends towards a shorter time to neurosurgery in the group treated in 2000-2001 (4.5 hours) compared to the group treated in 1997-1998 (5.5 h
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Books on the topic "Neurological outcomes"

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Michael, Swash, ed. Outcomes in neurological and neurosurgical disorders. Cambridge University Press, 1998.

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Ray, Fitzpatrick, Jenkinson Crispin 1962-, and Jenkinson Damian, eds. Health status measurement in neurological disorders. Radcliffe Medical Press, 2000.

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Uysal, Suzan, and Stephan A. Mayer. Neurological and Functional Outcomes Assessment. Edited by David L. Reich, Stephan Mayer, and Suzan Uysal. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190280253.003.0006.

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The evidence base for neuroprotection in critical care and perioperative medicine rests on outcomes research, a critical component of which is the quantitative assessment of the functional effects of neurological injury. Outcomes assessment is conceptualized hierarchically in terms of global outcome, impairment, disability, handicap, and health-related quality of life. This chapter describes the different classes of outcome measures and the instruments within each class that are most commonly used in clinical neuroprotection research. Desirable characteristics of outcome measures are described
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Swash, Michael. Outcomes in Neurological and Neurosurgical Disorders. Cambridge University Press, 2011.

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Swash, Michael, ed. Outcomes in Neurological and Neurosurgical Disorders. Cambridge University Press, 1998. http://dx.doi.org/10.1017/cbo9780511526947.

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Outcomes in Neurological and Neurosurgical Disorders. Cambridge University Press, 2006.

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Swash, Michael. Outcomes in Neurological and Neurosurgical Disorders. Cambridge University Press, 2009.

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Calinescu, Catalin. Outcomes of educational intervention with students with neurological disorders. 1997.

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Josman, Naomi, Lisa Tabor Connor, and David Jing-Piao Lin, eds. Performance and Participation Outcomes for Individuals With Neurological Conditions. Frontiers Media SA, 2020. http://dx.doi.org/10.3389/978-2-88966-149-7.

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Mallard, Carina, Mary Tolcos, and Justin Dean, eds. Neurological Outcomes in Preterm Infants – Current Controversies and Therapies for Brain Injury. Frontiers Media SA, 2020. http://dx.doi.org/10.3389/978-2-88963-494-1.

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Book chapters on the topic "Neurological outcomes"

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Pollock, B. E. "Patient Outcomes after Arteriovenous Malformation Radiosurgery." In Progress in Neurological Surgery. KARGER, 1998. http://dx.doi.org/10.1159/000062021.

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Dash, Sabyasachi. "Neuropathological Outcomes in Human Influenza and Respiratory Syncytial Virus Infections." In RNA Viruses and Neurological Disorders. CRC Press, 2023. http://dx.doi.org/10.1201/9781003285823-8.

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Dash, Sabyasachi. "Molecular and Cellular Alterations Underlying Neurological Outcomes in HIV Infection." In RNA Viruses and Neurological Disorders. CRC Press, 2023. http://dx.doi.org/10.1201/9781003285823-6.

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Barros Guinle, Maria Isabel, Ivan Lopez, Rahul Barve, et al. "Navigating Neuro-Oncology Care: Addressing Health Disparities in Access and Outcomes." In Achieving Equity in Neurological Practice. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-62727-9_12.

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Bartnicka, Joanna, Cristina Herrera, Raquel Portilla, et al. "Educational Needs in Neurological Rehabilitation – “Brain4Train” Survey Outcomes from European Countries." In Advances in Intelligent Systems and Computing. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-93882-0_37.

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Brown, Austin L., Kimberly P. Raghubar, Michael E. Scheurer, and Philip J. Lupo. "Acute and Long-term Neurological Complications of Acute Lymphoblastic Leukemia (ALL) Therapy in Latino Children." In Advancing the Science of Cancer in Latinos. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-14436-3_4.

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AbstractOver the last several decades, the survival for pediatric acute lymphoblastic leukemia (ALL) has increased from about 40–90%. However, current treatment strategies are associated with several acute and long-term toxicities, including neurotoxicity. Further, racial and ethnic disparities persist in both incidence and outcomes for ALL. In particular, Latino children experience both the highest incidence of ALL and less favorable outcomes. The incidence of neurotoxicity during ALL therapy potentially jeopardizes treatment efficacy, and long-term neurocognitive impairment profoundly affect
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Hobart, Jeremy, and Alan J. Thompson. "Measurement of neurological outcomes." In Diseases of the Nervous System. Cambridge University Press, 2002. http://dx.doi.org/10.1017/cbo9781316134993.008.

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S.V.Elkind, Mitchell, and Ralph L. Sacco. "Outcomes research in clinical neurology." In Investigating Neurological Disease. Cambridge University Press, 2001. http://dx.doi.org/10.1017/cbo9780511526909.008.

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Garton, Hugh, Frederick G. Barker, and Stephen J. Haines. "Neurosurgical Epidemiology and Outcomes Assessment." In Youmans Neurological Surgery. Elsevier, 2011. http://dx.doi.org/10.1016/b978-1-4160-5316-3.00012-5.

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"Outcomes of Epilepsy Surgery." In Neurological Disease and Therapy. CRC Press, 2005. http://dx.doi.org/10.1201/b14113-56.

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Conference papers on the topic "Neurological outcomes"

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Dionisio, Jefferson, Muhammad Rizwan, Hidetaka Suzuki, et al. "Is Attention All You Need for EEG to Predict Neurological Outcomes in Cardiac Arrest?" In 2024 IEEE EMBS International Conference on Biomedical and Health Informatics (BHI). IEEE, 2024. https://doi.org/10.1109/bhi62660.2024.10913569.

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Soltani, Nima, Vladislav Toronov, Rohit Mohindra, and Steve Lin. "Exploring Cerebral Oxygen Metabolism and Cytochrome Oxidase Dynamics During Cardiac Arrest." In Bio-Optics: Design and Application. Optica Publishing Group, 2025. https://doi.org/10.1364/boda.2025.jd1.5.

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Brain oxygen metabolism is a critical determinant of neurological outcomes during cardiac arrest (CA) and resuscitation. This study explores the relationships between the cerebral metabolic rate of oxygen (CMRO₂), redox cytochrome c oxidase (rCCO), and cerebral blood flow (CBF) in a pig model subjected to baseline, CA, cardiopulmonary resuscitation (CPR), and return of spontaneous circulation (ROSC). Using hyperspectral near-infrared spectroscopy (hNIRS) and laser Doppler flowmetry (LDF), we observed strong and distinct relationships between these variables. During CA, non-linear trends were e
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Abu-awwad, Raid, Mouhamad Mansour, Mohanad Alfaqih, Sana Quddus, and Alan Betensley. "Neurological Outcomes After Lung Transplantation." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3771.

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Brasiliense, L., H. Abdulrazek, P. Aguilar-Salinas, H. Abbad, T. Dumont, and M. El-Ghanem. "E-089 Outcomes of mechanical thrombectomy in patients with neurological disorders." In SNIS 17TH ANNUAL MEETING. BMJ Publishing Group Ltd., 2020. http://dx.doi.org/10.1136/neurintsurg-2020-snis.122.

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Lazarus, Theophilus. "SARS-CoV-2 infection and neuropsychological outcomes." In 2nd International Neuropsychological Summer School named after A. R. Luria “The World After the Pandemic: Challenges and Prospects for Neuroscience”. Ural University Press, 2020. http://dx.doi.org/10.15826/b978-5-7996-3073-7.10.

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The entire world is currently confronted with the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS.CoV.2), a novel betacoronavirus causing the deadly pandemic of coronavirus disease 2019 (COVID.19). Since there is now increasing reports of neurological and cognitive problems, the impact of COVID.19 on neuropsychological functioning is unknown but is likely to leave residual problems.
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Aljundi, L., C. A. Stanton, D. Triplett, et al. "Assessment of Neurological Outcomes and Mortality Post Intra Hospital Cardiac Arrest (IHCA)." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2882.

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Prasad, Shefalika, Juan Diego Alzate, Reed Mullen, Tanxia Qu, Kenneth Bernstein, and Joshua S. Silverman. "Neurological Outcomes of Radiosurgery for Brain Metastases in the Motor Cortex (P10-13.001)." In 2023 Annual Meeting Abstracts. Lippincott Williams & Wilkins, 2023. http://dx.doi.org/10.1212/wnl.0000000000203919.

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Cheng, P., H. Simms, and A. Abouharb. "E-225 Management, complications and neurological outcomes of aneurysmal subarachnoid haemorrhage in elderly patients." In SNIS 17TH ANNUAL MEETING. BMJ Publishing Group Ltd., 2020. http://dx.doi.org/10.1136/neurintsurg-2020-snis.256.

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Lougon, Isabela Turino, Taciana Maria Rolim Sampaio Oliveira, and Yan Ribeiro Francisco. "Therapeutic methods for lipomyelomeningocele: literature review." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.075.

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Introduction: Lipomyelomeningocele is a congenital malformation in which the neural plate lies outside the spinal canal. Patients younger than 6 months of age are neurologically asymptomatic. However, if not diagnosed, the disease evolves with deterioration of bowel and bladder functions and, later, with motor deficits (paralysis) and loss of sensation. Accordingly, a literature review was developed about the therapeutic methods that enable a better quality of life and prevent or control disease progression. Objectives: This literature review aims to elucidate leading updates in the literature
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Riccietti, Chiara, Maria Teresa Contaldo, Valentina Caldiera, et al. "O35 Addressing sex-related differences in neuro-psychological outcomes in endovascular treatments." In 16th Congress of the European Society of Minimally Invasive Neurological Therapy (ESMINT) 2024. BMJ Publishing Group Ltd., 2024. http://dx.doi.org/10.1136/jnis-2024-esmint.35.

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Reports on the topic "Neurological outcomes"

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Zhang, Yong. Efficacy and safety of corticosteroid therapy in patients with cardiac arrest: a meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.1.0014.

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Review question / Objective: Our goal was to assess the effect of primary treatment outcome (overall survival rate at hospital discharge, rate of sustained ROSC) and secondary outcomes (favorable neurological outcomes at hospital discharge and adverse events including hyperglycemia, insulin infusion, hypernatremia, infection, gastrointestinal bleeding, new or changing antibiotics, paresis, renal failure). Information sources: Two researchers (Zhou FW and Liu C) independently searched the PubMed, Embase, The Cochrane Library, Web of Science and China National Knowledge Internet (CNKI) databases
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Hu, Jihui, Yang Liu, Yi Zhang, Meng Zhang, and Li Zhang. Association Between Nutritional Status and Mortality/Neurological Outcomes in Stroke Patients: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2025. https://doi.org/10.37766/inplasy2025.6.0018.

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Marenco-Hillembrand, Lina, Michael A. Bamimore, Julio Rosado-Philippi, et al. The Evolving Landscape of Leptomeningeal Cancer from Solid Tumors: A Systematic Review of Clinical Trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.12.0112.

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Review question / Objective: Among adult patients with leptomeningeal carcinomatosis from solid tumors (population) treated with chemotherapy, targeted therapy, or immunotherapy (intervention and comparator) what are the differences in overall survival (OS) and progression-free survival (PFS) and treatment response based on clinical trial outcomes? Eligibility criteria: Included articles reported 1) human subjects ≥ 18 years 2) diagnosis of leptomeningeal carcinomatosis from solid tumors confirmed by imaging or cerebrospinal fluid (CSF) cytology and clinical or neurological symptoms 3) clinica
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Jelsma, Dorothee, Reza Abdollahipour, Farhad Ghadiri, et al. Evidence-based practice interventions for children and young people with Developmental Coordination Disorder - A scoping review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.2.0028.

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Review question / Objective: The aim of this review was to identify, qualify, evaluate and synthesise interventions used for children and young people with Developmental Coordination Disorder. The PCC was used to develop the review question: Population – children and young people with disorders of motor coordination aged to 25 years, not due to neurological disease or disorder eg. Cerebral Palsy. Concept - any method aimed to improve/treat/intervene in areas of motor learning, motor control, motor coordination or motor skill. Context - information on methods of delivery of interventions to con
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Westphal, Wagner. Update on Clinical Outcomes and Neurological Complications of Endoscopic Discectomy Using the Transforaminal Approach or Interlaminar Approach for Treatment of Lumbar Disc Herniation: Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.9.0116.

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Guan, Peiyu, Dingkun Gui, and Youhua Xu. Evaluation on the efficacy and safety of Panax notoginseng saponins in the treatment of stroke among elderly people - A systematic review and meta-analysis of 206 randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.3.0042.

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Review question / Objective: Population: The symptoms of the population were in line with the relevant diagnostic criteria for stroke both at home and abroad, and were confirmed as ischemic stroke by medical imaging tests such as MRI or CT.The subject groups were older adults with an average age of over 60, regardless of gender or race. Intervention: Intervention involves single use of PNS or combined use of PNS and WM or PNS and Treatment as usual (TAU). Comparator: All the patients in the controlled group underwent conventional routine treatment to improve their cerebral blood supply and dru
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Hsieh, Patrick, Eric Apaydin, Robert G. Briggs, et al. Diagnosis and Treatment of Tethered Spinal Cord. Agency for Healthcare Research and Quality (AHRQ), 2024. http://dx.doi.org/10.23970/ahrqepccer274.

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Objectives. To summarize the evidence regarding diagnosis, prophylactic treatment, symptomatic treatment, and repeat surgery of tethered spinal cord. Data sources. We searched PubMed®, Embase®, CINAHL, Web of Science, SCOPUS, clinicaltrials.gov, ICTRP, Cochrane Database of Systematic Reviews, PROSPERO, ECRI repository, G-I-N, MagicApp, and ClinicalKey from inception to March 2024; reference-mined reviews; and contacted research authors. Review methods. The review followed a detailed protocol and was supported by a Technical Expert Panel. Systematic review software (DistillerSR) was utilized fo
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Carney, Nancy, Tamara Cheney, Annette M. Totten, et al. Prehospital Airway Management: A Systematic Review. Agency for Healthcare Research and Quality (AHRQ), 2021. http://dx.doi.org/10.23970/ahrqepccer243.

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Objective. To assess the comparative benefits and harms across three airway management approaches (bag valve mask [BVM], supraglottic airway [SGA], and endotracheal intubation [ETI]) by emergency medical services in the prehospital setting, and how the benefits and harms differ based on patient characteristics, techniques, and devices. Data sources. We searched electronic citation databases (Ovid® MEDLINE®, CINAHL®, the Cochrane Central Register of Controlled Trials, the Cochrane Database of Systematic Reviews, and Scopus®) from 1990 to September 2020 and reference lists, and posted a Federal
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Yu, Beibei, Yongfeng Zhang, and Shouping Gong. Effects of miRNA-modified exosomes alleviate cerebral ischemic reperfusion injury in Pre-clinical Studies: A Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.5.0062.

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Review question / Objective: The purpose of this study was to investigate the effect of miRNA-modified exosomes in alleviating cerebral ischemic reperfusion injury compared with the non-treatment group. The research object is an animal model of middle cerebral artery occlusion. The research method is a controlled study. The primary outcome of this study was infarct volume, and the secondary outcome was neurobehavioral performance. Main outcome(s): The primary outcome of this study was Infarct volumes,which was measured by 2,3,5-triphenyltetranzolium chloride (TTC) staining. And it was calculat
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Wang, Dou, Tao Li, Jie Rong, Nan Wang, Xianling Fan, and Yongmei Yan. Is fluoxetine necessary for preventive treatment of post-stroke depression in stroke patients? A meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.3.0137.

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Review question / Objective: One third of patients may have post-stroke depression after a stroke. Poststroke depression seriously affects rehabilitation outcome, quality of life and mortality of stroke patients. Data on preventive treatment of fluoxetine for post-stroke depression in this setting are inconsistent. The purpose of this systematic review was to explore the efficacy and acceptability of fluoxetine for early antidepressant therapy in stroke patients, so as to better provide evidence-based medical evidence for clinical practice. To this end, the systematic review to be considered w
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