Relevant bibliographies by topics / Novel non-coding regulator RNA

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Novel non-coding regulator RNA'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Novel non-coding regulator RNA"

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Sevilla, Emma, Beatriz Martín-Luna, Andrés González, Jesús A. Gonzalo-Asensio, María Luisa Peleato, and María F. Fillat. "Identification of three novel antisense RNAs in the fur locus from unicellular cyanobacteria." Microbiology 157, no. 12 (2011): 3398–404. http://dx.doi.org/10.1099/mic.0.048231-0.

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The interplay between Fur (ferric uptake regulator) proteins and small, non-coding RNAs has been described as a key regulatory loop in several bacteria. In the filamentous cyanobacterium Anabaena sp. PCC 7120, a large dicistronic transcript encoding the putative membrane protein Alr1690 and an α-furA RNA is involved in the modulation of the global regulator FurA. In this work we report the existence of three novel antisense RNAs in cyanobacteria and show that a cis α-furA RNA is conserved in very different genomic contexts, namely in the unicellular cyanobacteria Microcystis aeruginosa PCC 780
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Schneider, Marius, and Peter B. Becker. "Nicht-codierende RNA als Regulator der Neurogenese." BIOspektrum 29, no. 1 (2023): 35–37. http://dx.doi.org/10.1007/s12268-023-1891-1.

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AbstractLong, non-coding (Inc) RNAs emerge as crucial regulators of gene expression. Their ability to interact with DNA and protein mediates the recruitment of regulators to defined chromosomal loci. LncRNAs are particularly abundant in brain tissues where they are involved in cell specification. We described a novel lncRNA, RUS (RNA upstream to Slitrk3), which interacts with epigenetic regulators and contributes to shaping the gene expression program of neural precursor cells towards neurogenesis.
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Limberis, Jason D., Alina Nalyvayko, Joel D. Ernst, and John Z. Metcalfe. "selSeq: A method for the enrichment of non-polyadenylated RNAs including enhancer and long non-coding RNAs for sequencing." PLOS ONE 18, no. 11 (2023): e0289442. http://dx.doi.org/10.1371/journal.pone.0289442.

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Non-polyadenylated RNA includes a large subset of crucial regulators of RNA expression and constitutes a substantial portion of the transcriptome, playing essential roles in gene regulation. For example, enhancer RNAs are long non-coding RNAs that perform enhancer-like functions, are bi-directionally transcribed, and usually lack polyA tails. This paper presents a novel method, selSeq, that selectively removes mRNA and pre-mRNA from samples enabling the selective sequencing of crucial regulatory elements, including non-polyadenylated RNAs such as long non-coding RNA, enhancer RNA, and non-cano
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Li, Siqi, Zhengping Xu, and Jinghao Sheng. "tRNA-Derived Small RNA: A Novel Regulatory Small Non-Coding RNA." Genes 9, no. 5 (2018): 246. http://dx.doi.org/10.3390/genes9050246.

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Kuai, Zheng, Meiting Chen, yang yu, Fan Yang, and chunxiang Zhang. "UP-REGULATION OF LONG NON-CODING RNA MORBID ATTENUATES SENESCENCE." Innovation in Aging 3, Supplement_1 (2019): S90. http://dx.doi.org/10.1093/geroni/igz038.344.

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Abstract Aging is the inevitable, irreversible decline in function on the cellular and organ level leading to increased incidence of the most frequent diseases such as cancer and cardiovascular disease, that occurs over time. whereas the molecular mechanisms of senescence remain largely unknown. Here we identified that a novel long noncoding RNA, Morrbid was significantly decreased in different organs of aged mice, such as heart, liver, spleen, lung, kidney and brain. Interestingly, the telomeres length of Morrbid KO mice were significantly shorted than the WT mice at the same age. We also fou
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Ma, Ning, Lingyun Zhou, Yanfen Zhang, Yuting Jiang, and Xu Gao. "Intragenic microRNA and long non-coding RNA: novel potential regulator ofIGF2-H19imprinting region." Evolution & Development 16, no. 1 (2014): 1–2. http://dx.doi.org/10.1111/ede.12057.

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Rossi, Francesca, Alvaro Centrón-Broco, Dario Dattilo, et al. "CircVAMP3: A circRNA with a Role in Alveolar Rhabdomyosarcoma Cell Cycle Progression." Genes 12, no. 7 (2021): 985. http://dx.doi.org/10.3390/genes12070985.

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Circular RNAs (circRNAs), a class of covalently closed RNAs formed by a back-splicing reaction, have been involved in the regulation of diverse oncogenic processes. In this article we describe circVAMP3, a novel circular RNA overexpressed in RH4, a representative cell line of alveolar rhabdomyosarcoma. We demonstrated that circVAMP3 has a differential m6A pattern opposed to its linear counterpart, suggesting that the two isoforms can be differently regulated by such RNA modification. Moreover, we show how circVAMP3 depletion in alveolar rhabdomyosarcoma cells can impair cell cycle progression,
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Greene, J. P., G. Blackshields, O. Casey, et al. "circular RNA: A novel regulatory non-coding RNA expressed in prostate cancer." Annals of Oncology 27 (October 2016): vi531. http://dx.doi.org/10.1093/annonc/mdw392.17.

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Zhu, Min, Xiao Li, Shengtao Zhu, Peng Li, Li Min, and Shutian Zhang. "Long non-coding RNA BLACAT1, a novel promising biomarker and regulator of human cancers." Biomedicine & Pharmacotherapy 132 (December 2020): 110808. http://dx.doi.org/10.1016/j.biopha.2020.110808.

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Porozhan, Yevheniia, Mikkel Carstensen, Sandrine Thouroude, et al. "Defective Integrator activity shapes the transcriptome of patients with multiple sclerosis." Life Science Alliance 7, no. 10 (2024): e202402586. http://dx.doi.org/10.26508/lsa.202402586.

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HP1α/CBX5 is an epigenetic regulator with a suspected role in multiple sclerosis (MS). Here, using high-depth RNA sequencing on monocytes, we identified a subset of MS patients with reduced CBX5 expression, correlating with progressive stages of the disease and extensive transcriptomic alterations. Examination of rare non-coding RNA species in these patients revealed impaired maturation/degradation of U snRNAs and enhancer RNAs, indicative of reduced activity of the Integrator, a complex with suspected links to increased MS risk. At protein-coding genes, compromised Integrator activity manifes
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Dissertations / Theses on the topic "Novel non-coding regulator RNA"

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Pettini, Tom. "The role of novel long non-coding RNAs in Hox gene regulation." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/the-role-of-novel-long-noncoding-rnas-in-hox-gene-regulation(c8e44900-3ac0-40be-8ec6-b50179381d17).html.

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Whole genome transcriptome analysis has revealed that a large proportion of the genome in higher metazoa is transcribed, yet only a small proportion of this transcription is protein-coding. One possible function of non-coding transcription is that it enables complex and diverse body plans to evolve through variation in deployment of a relatively common set of protein-coding genes. Functional studies suggest that long non-coding RNAs (lncRNAs) regulate gene expression via diverse mechanisms, operating in both cis and trans to activate or repress target genes. An emerging theme common to lncRNA
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Chong, Vanessa. "Biotagging, a genetically encoded toolkit in the zebrafish, reveals novel non-coding RNA players during neural crest and myocardium development." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:26b7d1a0-3f03-4518-97c4-566cc5d5bf02.

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Complex multicellular organisms are composed of at least 200 cell types, which contain the same DNA "black box" of genetic information. It is the precise regime according to which they express their genes, exquisitely controlled by gene regulatory circuits, that defines their cellular identity, morphology and function. We have developed an in vivo biotinylation method that uses genetically encoded components in zebrafish, termed biotagging, for genome-wide regulatory analysis of defined embryonic cell populations. By labelling selected proteins in specific cell types, biotagging eliminates bac
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Chang, Yueming. "Investigation of two early events in amyotrophic lateral sclerosis mRNA oxidation and up-regulation of a novel protective factor MSUR1 /." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1196182155.

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de, Bony Eric James. "Novel insights into the function and regulation of coding and long non-coding RNAs." Doctoral thesis, Universite Libre de Bruxelles, 2018. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/268600.

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Le dogme central de la biologie repose sur la production de protéines à partir de notre ADN. L’ADN est d’abord transcrit en ARN et celui-ci est ensuite traduit en protéine. C’est donc en cette dernière qu’est localisé le “pouvoir exécutif” de la cellule, ce qui explique le fait que les protéines soient devenues le centre d’attention de la recherche. L’ARN, quant à lui, est donc depuis longtemps considéré comme une molécule intermédiaire, dont l’unique raison d’être est le transfert d’information entre l’ADN et les protéines. Pourtant, ces dernières années, les avancées technologiques ont révél
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Han, Xiao. "Interaction of the non coding RNA 7SK, a regulator of human transcription elongation, with the LaRP7 protein." Electronic Thesis or Diss., Paris Sciences et Lettres (ComUE), 2016. http://www.theses.fr/2016PSLEE008.

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L’ARN non-codant 7SK forme la charpente d’un complexe, 7SK snRNP, qui régule l’activité du facteur d’élongation de la transcription P-TEFb, intervenant dans la levée des pauses transcriptionelles chez les métazoaires. Le 7SK snRNP comprend les protéines LARP7, essentielle pour la stabilité de l’ARN 7SK et MePCE, participant à sa coiffe. Dans le cadre d’une investigation du rapport entre structure et fonction de l’ARN7SK, le projet était de comprendre commen la protéine LARP7 reconnait et assemble l’ARN dans le 7SK snRNP. La protéine LARP7, membre d’une famille reliée à laprotéine La, est spéci
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Han, Xiao. "Interaction of the non coding RNA 7SK, a regulator of human transcription elongation, with the LaRP7 protein." Thesis, Paris Sciences et Lettres (ComUE), 2016. http://www.theses.fr/2016PSLEE008/document.

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L’ARN non-codant 7SK forme la charpente d’un complexe, 7SK snRNP, qui régule l’activité du facteur d’élongation de la transcription P-TEFb, intervenant dans la levée des pauses transcriptionelles chez les métazoaires. Le 7SK snRNP comprend les protéines LARP7, essentielle pour la stabilité de l’ARN 7SK et MePCE, participant à sa coiffe. Dans le cadre d’une investigation du rapport entre structure et fonction de l’ARN7SK, le projet était de comprendre commen la protéine LARP7 reconnait et assemble l’ARN dans le 7SK snRNP. La protéine LARP7, membre d’une famille reliée à laprotéine La, est spéci
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Peters, Rosie Elizabeth. "Identifying novel targets for the snoRNA class of stable non-coding RNAs." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33123.

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Non-coding RNAs (ncRNAs) are a subset of RNAs that do not code for protein. They are divided into a number of different groups based on their function and targets. Small nucleolar RNAs (snoRNAs) are ncRNAs that have long been known to function as guides for ribosomal RNA (rRNA) modifying enzymes. They are classified into two major groups: box C/D snoRNAs and box H/ACA snoRNAs. Most box C/D snoRNAs direct the 2'-O-methylation of rRNA substrates, but some lack known targets and are therefore termed 'orphan snoRNAs'. Studies have implicated orphan snoRNAs in pre-mRNA processing and stability, but
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Niemczyk, Malwina. "Epigenetic and transcriptional relationship between a novel long non-coding RNA GNG12-AS1 and imprinted DIRAS3." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708234.

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Zhang, Zhouwei. "Investigation of DNA and RNA markers by novel technologies demonstrates DNA content intratumoral heterogeneity and long non-coding RNA aberrations in breast tumors." ScholarWorks @ UVM, 2014. https://scholarworks.uvm.edu/graddis/323.

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BACKGROUND: Breast cancer is the most commonly diagnosed cancer and second leading cancer death cause among females in the U.S.A. About 1 in 8 women in U.S will develop invasive breast cancer over the course of her lifetime. In 2013, 234,580 new invasive breast cancer cases are expected to occur in women within the US and approximately 64,640 non-invasive carcinomas in situ were diagnosed in 2013, most of which were ductal carcinoma in situ (DCIS). Along with technological advances, a wide variety of candidate biomarkers have been proposed for cancer diagnosis and prognosis, including DNA cont
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Kacharia, Fenil Rashmin. "Investigating the Origin and Functions of a Novel Small RNA in Escherichia coli." PDXScholar, 2016. http://pdxscholar.library.pdx.edu/open_access_etds/3106.

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Non-coding small RNAs (sRNAs) regulate various cellular processes in bacteria. They bind to a chaperone protein Hfq for stability and regulate gene expression by base-pairing with target mRNAs. Although the importance of sRNAs in bacteria has been well established, the mode of origination of novel sRNA genes is still elusive, mainly because the rapid rate of evolution of sRNAs obscures their original sources. To overcome this impediment, we identified a recently formed sRNA (EcsR2) in E. coli, and show that it evolved from a degraded bacteriophage gene. Our analyses also revealed that young sR
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Books on the topic "Novel non-coding regulator RNA"

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Barrett, Lucy W. Untranslated gene regions and other non-coding elements: Regulation of eukaryotic gene expression. Springer, 2013.

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Roberts, Kristina Anne. Mutation of a novel non-coding RNA causes vestibular malformation in the Epistatic circler mouse. 2009.

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Fletcher, Sue, Lucy W. Barrett, and Steve D. Wilton. Untranslated Gene Regions and Other Non-coding Elements: Regulation of Eukaryotic Gene Expression. Springer, 2013.

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Grant, Warren, and Martin Scott-Brown. Principles of oncogenesis. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0322.

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It is obvious that the process of developing cancer—oncogenesis—is a multistep process. We know that smoking, obesity, and a family history are strong independent predictors of developing malignancy; yet, in clinics, we often see that some heavy smokers live into their nineties and that some people with close relatives affected by cancer spend many years worrying about a disease that, in the end, they never contract. For many centuries scientists have struggled to understand the process that make cancer cells different from normal cells. There were those in ancient times who believed that tumo
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Book chapters on the topic "Novel non-coding regulator RNA"

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Guo, Xingyi, and Deyou Zheng. "Regulatory Roles of Novel Small RNAs from Pseudogenes." In Non Coding RNAs in Plants. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-19454-2_12.

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Kurokawa, Riki. "Long Noncoding RNA as a Regulator for Transcription." In Long Non-Coding RNAs. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-16502-3_2.

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Koksoy, Hale. "The Role of Genetics and Epigenetics in Diabetes Progress." In Current Multidisciplinary Approach to Diabetes Mellitus Occurrence Mechanism. Nobel Tip Kitabevleri, 2023. http://dx.doi.org/10.69860/nobel.9786053359104.1.

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Genetics and epigenetics play critical roles in the progression and manifestation of diabetes mellitus. Genetic factors contribute significantly to an individual’s susceptibility to developing diabetes, influencing aspects such as insulin production, glucose metabolism, and pancreatic function. Variations in genes associated with insulin secretion (e.g., TCF7L2) and insulin sensitivity (e.g., IRS1) can predispose individuals to type 2 diabetes. Additionally, epigenetic mechanisms, which involve modifications in gene expression without altering the underlying DNA sequence, are increasingly reco
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G. Fagan, Steven, and Shona Pfeiffer. "Emerging Roles of Non-Coding RNA in Neuronal Function and Dysfunction." In Recent Advances in Neurochemistry [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.101327.

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Advancements in RNA sequencing technologies in recent years have contributed greatly to our understanding of the transcriptome and the now widely recognized multifaceted functions of RNA. The discovery and functional analysis of an increasing number of novel small non-coding RNAs (ncRNAs) has highlighted their importance as critical regulators of gene expression and brain function. In particular, two diverse classes of ncRNAs, microRNAs (miRNAs) and tRNA-derived small RNAs (tsRNAs), are especially abundant in the nervous system and play roles in regulation of gene expression and protein transl
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Villegas O., Jaime, Vincenzo Borgna, Carlos Contreras, Emanuel Jeldes, Luis O. Burzio, and Verónica Burzio. "Long Non-Coding Mitochondrial RNAs as Novel Molecular Target for Bladder Cancer Treatment." In Bladder Cancer [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.108899.

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Bladder cancer (BC) is the sixth most common cause of cancer; BC risk increases with age and is more common among men than women. Upon diagnosis, the 5-year relative survival rate for patients is approximately 77%. The treatment options available for bladder cancer include chemotherapy, radiation therapy, immunotherapy, targeted therapy, and surgery. Despite the advances in therapeutically novel approaches, BC remains an important problem of public health. Long non-coding RNA (lncRNA) is defined as non-protein-coding RNA molecule longer than 200 nucleotides. Recent findings have highlighted th
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C. Bester, Assaf. "Deciphering the Hidden Language of Long Non-Coding RNAs: Recent Findings and Challenges." In Genetics. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.112449.

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Long non-coding RNAs (lncRNAs) are crucial non-coding RNA genes involved in diverse cellular processes. However, the mechanisms underlying their emergence and functions remain incompletely understood. A major challenge in the field is to understand how lncRNA sequences affect their function. In recent years, comprehensive genetic and genomic studies have started to unfold the function of lncRNAs through their interactions, cellular organization, and structure. This comprehensive review delves into the intricate interplay between lncRNA sequences and their functional implications. Unlike other
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Radanova, Maria. "Transcribed-Ultra Conserved Regions (T-UCRs) a New Light on a Dark Matter." In Noncoding RNA - The Dark Matter of the Genome [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.113015.

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Transcribed Ultra-Conserved Regions (T-UCRs) are a novel class of long non-coding RNAs derived from Ultra-Conserved Regions (UCRs) of DNA. The discovery of cancer-specific mutations in UCRs and their location in cancer-associated genomic regions suggests that T-UCRs also play a role in carcinogenesis. However, the mechanisms behind their actions remain unclear. Their interactions with microRNAs are not well understood and are currently a subject of debate. Like other non-coding RNAs, T-UCRs exhibit tissue- and disease-specific expression, making them promising candidates for biomarkers or ther
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Eglenen, Zeynep Nur, and Stuart James Lucas. "Food Allergy: Molecular Basis and the Potential Novel Role of microRNAs." In Matematik ve Fen Bilimleri Üzerine Araştırmalar-IV. Özgür Yayınları, 2023. http://dx.doi.org/10.58830/ozgur.pub392.c1549.

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Food allergy is a growing public health problem worldwide, with surveys suggesting that between 2-10% of people are affected at some level. However, the causes, symptoms and severity of food allergies vary widely among individuals. Moreover, although many of the immunological mechanisms underlying food allergy have been investigated, the reasons why some consumers develop allergies but others do not are still not fully understood.
 In this chapter, we give an overview of current knowledge concerning the epidemiology and immunology of food allergies. We also discuss recent developments in
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Akbari, Kuldeep, Sunil Patel, Dimple Gor, Vidyut Balar, Hardik Patel, and Parth Bagadiya. "Non-coding RNA as a regulator for developmental processes in plants." In Non-coding RNA in Plants. Elsevier, 2025. https://doi.org/10.1016/b978-0-443-21784-5.00009-5.

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Schober, Andreas, Saffiyeh Saboor Maleki, and Maliheh Nazari-Jahantigh. "Regulatory Non-coding RNAs in Atherosclerosis." In Handbook of Experimental Pharmacology. Springer Berlin Heidelberg, 2020. http://dx.doi.org/10.1007/164_2020_423.

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AbstractRegulatory RNAs like microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) control vascular and immune cells’ phenotype and thus play a crucial role in atherosclerosis. Moreover, the mutual interactions between miRNAs and lncRNAs link both types of regulatory RNAs in a functional network that affects lesion formation. In this review, we deduce novel concepts of atherosclerosis from the analysis of the current data on regulatory RNAs’ role in endothelial cells (ECs) and macrophages. In contrast to arterial ECs, which adopt a stable phenotype by adaptation to high shear stress, macrophag
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Conference papers on the topic "Novel non-coding regulator RNA"

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Omote, N., K. Sakamoto, Q. Li, et al. "Long Non-Coding RNA TINCR Is a Novel Regulator of Human Bronchial Epithelial Cell Differentiation." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a5987.

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Hu, Ruoxi, Joeseph F. Nabhan, and Quan Lu. "RNAi Screen Identifies A Novel Non-coding RNA That Regulates ²2-Adrenergic Receptor Expression." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5603.

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Zhang, Ningyi, Liran Juan, and Tianyi Zang. "NCRR: A novel method for measuring disease similarity based on non-coding RNA regulation." In 2020 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2020. http://dx.doi.org/10.1109/bibm49941.2020.9313181.

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Gutschner, Tony, Monika Hämmerle, Moritz Eißmann, et al. "Abstract 1121: The long non-coding RNA MALAT1 is an essential gene regulator for lung cancer metastasis in a novel human knockout model ." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-1121.

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Malik, Rohit, Matthew K. Iyer, John R. Prensner, et al. "Abstract 1120: Identification and characterization of a novel androgen-regulated long non-coding RNA in prostate cancer." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-1120.

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Pichler, Martin, Stefanie Cerk, Verena Stiegelbauer, Daniela Schwarzenbacher, and Hui Ling. "Abstract 988: A novel long non-coding RNA, TSA-LINC2, regulates cellular growth and is associated with poor prognosis in breast cancer." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-988.

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Jiang, Wei, Shlomit Brodie, Simona Cazacu, et al. "Abstract 2543: The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2543.

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Polycarpou-Schwarz, Maria, Tony Gutschner, Monika Hämmerle, et al. "Abstract 1824: The non-coding RNA landscape of lung, liver and breast cancer reveals novel tumor-associated ncRNAs, concerted regulation and unexpected tissue specificity." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-1824.

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Zambalde, Erika Pereira, Ana Carolina Rodrigues, Rubens Silveira Lima, Enilze Maria Souza Fonseca Ribeiro, and Jaqueline Carvalho Oliveira. "TLNC-UC.147, A NOVEL LONG RNA (lncRNA) FROM AN ULTRACONSERVED REGION AS POTENTIAL BIOMARKER IN LUMINAL A BREAST CANCER." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1052.

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Introduction: Long RNAs are non-coding RNAs with more than 200 nucleotides in length, with essential regulatory roles in several biological processes, including in breast cancer (BC). The human genome contains 481 ultraconserved regions, which are genomic stretches of over 200 base pairs conserved among humans, rats, and mice. Most of these regions are transcriptionally active (T-UCRs), and several are differentially expressed in tumors. Some T-UCRs have been functionally characterized, but few have been associated with BC. Objectives: In this study, we aimed to expand the knowledge of T-UCRs
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Manchon, Laurent, Audrey Vautrin, Jamal Tazi, Aude Garcel, and Noelie Campos. "Targeting Long Non-Coding RNA splicing by novel candidate drug." In 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2019. http://dx.doi.org/10.1109/bibm47256.2019.8982977.

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Reports on the topic "Novel non-coding regulator RNA"

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Tucker, Mark L., Shimon Meir, Amnon Lers, Sonia Philosoph-Hadas, and Cai-Zhong Jiang. Elucidation of signaling pathways that regulate ethylene-induced leaf and flower abscission of agriculturally important plants. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597929.bard.

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The Problem: Abscission is a highly regulated process, occurring as a natural terminal stage of development, in which various organs are separated from the parent plant. In most plant species, the process is initiated by a decrease in active auxin in the abscission zone (AZ) and an increase in ethylene, and may be accelerated by postharvest or environmental stresses. Another potential key regulator in abscission is IDA (Inflorescence Deficient in Abscission), which was identified as an essential peptide signal for floral organ abscission in Arabidopsis. However, information is still lacking re
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Friedman, Haya, Julia Vrebalov, and James Giovannoni. Elucidating the ripening signaling pathway in banana for improved fruit quality, shelf-life and food security. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7594401.bard.

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Background : Banana being a monocot and having distinct peel and pulp tissues is unique among the fleshy fruits and hence can provide a more comprehensive understanding of fruit ripening. Our previous research which translated ripening discoveries from tomato, led to the identification of six banana fruit-associated MADS-box genes, and we confirmed the positive role of MaMADS1/2 in banana ripening. The overall goal was to further elucidate the banana ripening signaling pathway as mediated by MADS-boxtranscriptional regulators. Specific objectives were: 1) characterize transcriptional profiles
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Lindsay, Denise, J. Mylroie, Kurt Gust, Elijah Cowan, and Richard Lance. Investigation of environmental messenger RNA (e-mRNA) for detection of genes sensitive to PFOS exposure in zebrafish (Danio rerio). Engineer Research and Development Center (U.S.), 2025. https://doi.org/10.21079/11681/49841.

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Environmental RNA (eRNA) is gaining ground as an environmental monitoring and assessment tool. Whereas environmental DNA is mainly utilized for species detection, and sometimes population size estimation, eRNA potentially provides additional scales or classes of inference. eRNA’s comparatively more rapid signal decay rates provide narrower temporal windows for species presence, while detection of messenger RNAs or other cell regulatory RNAs in environmental samples could provide evidence of genomic responses to environmental stressors. We tested select environmental messenger RNAs (e-mRNAs) of
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Ostersetzer-Biran, Oren, and Jeffrey Mower. Novel strategies to induce male sterility and restore fertility in Brassicaceae crops. United States Department of Agriculture, 2016. http://dx.doi.org/10.32747/2016.7604267.bard.

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Abstract Mitochondria are the site of respiration and numerous other metabolic processes required for plant growth and development. Increased demands for metabolic energy are observed during different stages in the plants life cycle, but are particularly ample during germination and reproductive organ development. These activities are dependent upon the tight regulation of the expression and accumulation of various organellar proteins. Plant mitochondria contain their own genomes (mtDNA), which encode for rRNAs, tRNAs and some mitochondrial proteins. Although all mitochondria have probably evo
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Ozias-Akins, P., and R. Hovav. molecular dissection of the crop maturation trait in peanut. United States-Israel Binational Agricultural Research and Development Fund, 2020. http://dx.doi.org/10.32747/2020.8134157.bard.

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Crop maturation is one of the most recognized characteristics of peanut, and it is crucial for adaptability and yield. However, not much is known regarding its genetic and molecular control. The goals of this project were to study the molecular-genetic components that control crop maturation in peanut and identify candidate genes. Crop maturation was studied directly by phenotyping the maturity level or through other component traits such as flowering pattern and branching habit. Six different RIL populations (HH, RR, CC, FNC, TGT and FLIC) were used for the genetic analysis. In total, 14 QTLs
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Flaishman, Moshe, Herb Aldwinckle, Shulamit Manulis, and Mickael Malnoy. Efficient screening of antibacterial genes by juvenile phase free technology for developing resistance to fire blight in pear and apple trees. United States Department of Agriculture, 2008. http://dx.doi.org/10.32747/2008.7613881.bard.

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Objectives: The original objectives of this project were to: Produce juvenile-free pear and apple plants and examine their sensitivity to E. amylovora; Design novel vectors, for antibacterial proteins and promoters expression, combined with the antisense TFL1 gene, and transformation of Spadona pear in Israel and Galaxy apple in USA. The original objectives were revised from the development of novel vectors with antibacterial proteins combined with the TFL-1 due to the inefficiency of alternative markes initially evaluated in pear, phoshomannose-isomerase and 2-deoxyglucose-6-phosphate phospha
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Christopher, David A., and Avihai Danon. Plant Adaptation to Light Stress: Genetic Regulatory Mechanisms. United States Department of Agriculture, 2004. http://dx.doi.org/10.32747/2004.7586534.bard.

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Original Objectives: 1. Purify and biochemically characterize RB60 orthologs in higher plant chloroplasts; 2. Clone the gene(s) encoding plant RB60 orthologs and determine their structure and expression; 3. Manipulate the expression of RB60; 4. Assay the effects of altered RB60 expression on thylakoid biogenesis and photosynthetic function in plants exposed to different light conditions. In addition, we also examined the gene structure and expression of RB60 orthologs in the non-vascular plant, Physcomitrella patens and cloned the poly(A)-binding protein orthologue (43 kDa RB47-like protein).
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Levin, Ilan, John W. Scott, Moshe Lapidot, and Moshe Reuveni. Fine mapping, functional analysis and pyramiding of genes controlling begomovirus resistance in tomato. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7594406.bard.

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Abstract. Tomato yellow leaf curl virus (TYLCV), a monopartitebegomovirus, is one of the most devastating viruses of cultivated tomatoes and poses increasing threat to tomato production worldwide. Because all accessions of the cultivated tomato are susceptible to these viruses, wild tomato species have become a valuable resource of resistance genes. QTL controlling resistance to TYLCV and other begomoviruses (Ty loci) were introgressed from several wild tomato species and mapped to the tomato genome. Additionally, a non-isogenic F₁diallel study demonstrated that several of these resistance sou
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