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Dissertations / Theses on the topic 'PSYCHOTROPIC DRUGS/therapeutic use'

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Published: 4 June 2021
Last updated: 2 February 2022

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1

Öhman, Daniel. "Bioanalytical development for application in therapeutic drug monitoring : focus on drugs used in psychiatry /." Linköping : Univ, 2003. http://www.bibl.liu.se/liupubl/disp/disp2003/med775s.pdf.

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2

Costa, Elisabeth Maria Sene. ""Psicoterapia psicodramática focal: análise qualitativa e quantitativa no transtorno depressivo maior"." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5142/tde-19082005-151240/.

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A importância de algumas abordagens psicoterápicas associadas à farmacoterapia no tratamento do Transtorno Depressivo Maior tem sido bastante destacada, no entanto, existem poucos dados sobre a Psicoterapia Psicodramática. O presente estudo comparou 20 pacientes com diagnóstico de TDM em uso de medicamentos antidepressivos e avaliados pela Escala de Depressão de HAM-D17 (escores entre 7 e 20), divididos em dois grupos: dez pacientes do Grupo Psicoterápico (GP) participaram de 4 sessões individuais de psicoterapia psicodramática e 24 de grupo. Dez pacientes do Grupo Controle (GC) não participar
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3

Vanderpot, Lynne Esther. "The interrelationship between spirituality and psychiatric medication use : a hermeneutic phenomenological study." Thesis, University of Aberdeen, 2015. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=229440.

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This thesis explores the perceived relationship between spirituality and psychiatric medication use in individuals living with severe mental health problems. The biological approach to mental health treatment is the dominant paradigm of care across the Western world, which justifies the use of psychopharmacology as a first-line therapy. In the last 30 years, the steady rise in the use of prescription medications has generated much debate and controversy. Historically, much of what we know about psychiatric medication comes from professionals and experts. Comparatively little is known about the
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4

Bell, Paul. "The use of saccadic eye movements in the clinical psychopharmacology of psychotropic drugs." Thesis, Queen's University Belfast, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261766.

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5

Mathis, Leigh Ann. "Student Psychotropic Drug Use, Past Therapy Experience and Length of Therapy." TopSCHOLAR®, 2008. http://digitalcommons.wku.edu/theses/49.

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6

Giron, Maria Stella T. "The rational use of drugs in a population of very old persons /." Stockholm : [Karolinska institutets bibl.], 2002. http://diss.kib.ki.se/2002/91-7349-155-1.

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7

Aldughaim, Mohammed. "The use of a novel TIMP3 peptide to specifically target therapeutic drugs to tumours." Thesis, University of Sheffield, 2017. http://etheses.whiterose.ac.uk/19957/.

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8

Mawanda, Francis. "Emerging risk factors for dementia: associations between clinical infections, PTSD, psychotropic PTSD medication use, and the risk for dementia." Diss., University of Iowa, 2015. https://ir.uiowa.edu/etd/2117.

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Dementia is a major public health problem worldwide. Emerging research indicates that clinical infections and PTSD could be important risk factors for dementia. However, evidence for infections and the risk of dementia primarily examines central nervous system (CNS) infections. Extant epidemiological evidence for systemic bacterial infections and the risk for dementia is limited while that for PTSD and the risk for dementia did not account for psychotropic medications commonly used in management of PTSD and could affect cognitive function. The purpose of this study was to 1) review the evidenc
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9

Pathy, Kala. "Bioavailability problems in clinical neuropharmacology with special reference to (1) generic phenytoin and (2) madopar HBS." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1994. http://hub.hku.hk/bib/B31214551.

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10

Meyer, Eric. "Comparative bioavailability and ranking of topical corticosteroid formulations." Thesis, Rhodes University, 1985. http://hdl.handle.net/10962/d1001471.

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Numerous experiments in recent years have indicated differences in the bioavailability of corticosteroids from seemingly identical topical dosage forms. The human blanching assay was utilized in this study to assess the comparative blanching activities of various locally manufactured proprietary corticosteroid preparations. The first experiment was performed to assess the relative blanching activities of six semi - solid preparations containing the same concentration of betamethasone 17-valerate. The preparations used were Betnovate cream and ointment, Persivate cream and ointment and Celestod
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11

Kuno, Ai. "Growing up with one parent: its association with psychotropic drug use in young adulthood : A register-based study in Sweden." Thesis, Stockholms universitet, Centrum för forskning om ojämlikhet i hälsa (CHESS), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-132258.

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The overall aim of this study was to investigate the association between family structure in childhood and mental health problems in young adulthood. A prospective cohort study was conducted with 481,777 individuals with complete follow-up information, which was obtained from national registers in Sweden. Individuals who were living with only one biological parent at age 17 were compared with those who grew up with two parents with regard to retrieval of prescribed psychotropic drugs at age 35. The association was examined by Cox regression analyses with equal survival time for all individuals
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12

Komperlla, Mahesh Kumar. "The formulation and evaluation of rapid release tablets manufactured from Artemisia Afra plant material." Thesis, University of the Western Cape, 2004. http://etd.uwc.ac.za/index.php?module=etd&amp.

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<p>Infusions, decoctions, alcoholic preparations and other dosage forms of Artemisia afra are frequently used in South African traditional medicine. Generally when these preparations are made without applying good manufacturing practices they do not meet microbial quality control standards, safety and toxicity criteria and encourage poor patients compliance. To overcome the aforementioned disadvantages of traditional dosage forms a sold dosage form, i.e. a table might be recommended. The first objective of this study was to formulate and manufacture a rapid release tablet dosage of Artemisia a
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13

Garrett, Ian Ross. "Studies of the effect of metal containing drugs on acute and chronic inflammation /." Title page, table of contents and summary only, 1986. http://web4.library.adelaide.edu.au/theses/09PH/09phg2386.pdf.

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14

Hung, Yik-fong Caroline, and 洪益芳. "A survey of albumin use by surgeons and ICU doctors in Hong Kong public hospitals." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B45010055.

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15

Lövheim, Hugo. "Psychotropic and analgesic drug use among old people : with special focus on people living in institutional geriatric care." Doctoral thesis, Umeå universitet, Institutionen för samhällsmedicin och rehabilitering, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1608.

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Old people in general, and those affected by dementia disorders in particular, are more sensitive to drug side effects than younger people. Despite this, the use of nervous system drugs and analgesics among old people is common, and has increased in recent years. Institutional geriatric care accommodates people who need round-the-clock supervision and care, due to somatic, psychiatric, cognitive or behavioral symptomatology. A majority of those living in institutional geriatric care suffers from dementia disorders. This thesis is based on three different data collections. Two large cross-secti
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16

Perkonigg, Axel, Roselind Lieb, and Hans-Ulrich Wittchen. "Substance Use, Abuse and Dependence in Germany." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-99907.

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To provide background information about previous findings about the prevalence of use, abuse and dependence of various substances (nicotine, alcohol, prescription and illicit drugs) findings of available epidemiological studies in Germany from the 1980s and 1990s are summarized and critically evaluated. Focusing on findings of substance use surveys in adolescents and young adults the review indicates: (a) a considerable number of large scale questionnaire surveys in general population samples documenting the frequency of use and patterns of use of most substances; (b) indications of increasing
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17

Chew, Angela Christine. "The anti-proliferative effects of thiazolidinediones and non-steriodal anti-inflammatory drugs on androgen-independent prostate cancer." University of Western Australia. School of Medicine and Pharmacology, 2009. http://theses.library.uwa.edu.au/adt-WU2009.0200.

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[Truncated abstract] In recent years a better understanding of the biology of PPAR , a nuclear transcription factor, has emerged, leading to a resurgence in targeting PPAR for chemotherapy. The family of synthetic PPAR agonists, the thiazolidinediones (TZDs), and non-steroidal anti-inflammatory drugs (NSAIDs) have been implicated in the inhibition of cell proliferation, apoptosis and cell cycle arrest of androgen-sensitive (LNCaP) and androgen-independent (PC-3 and DU145) prostate cancer cells generating much interest in their use for potential curative cancer therapies. In light of the pote
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18

Du, Plessis-Stoman Debbie. "A combination of platinum anticancer drugs and mangiferin causes increased efficacy in cancer cell lines." Thesis, Nelson Mandela Metropolitan University, 2010. http://hdl.handle.net/10948/d1016160.

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This thesis mainly deals with some biochemical aspects regarding the efficacy of novel platinum anticancer compounds alone and in combination with mangiferin, as part of a broader study in which both chemistry and biochemistry are involved. Various novel diamine and N-S donor chelate compounds of platinum II and IV have been developed in which factors such as stereochemistry, ligand exchange rate and biocompatibility were considered as additional parameters. In the first order testing, each of these compounds was tested with reference to their “killing” potential by comparing their rate of kil
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19

Tam, Chun-wai, and 談振偉. "Combating prostate diseases with ethnobotanical drugs: inhibition of prostate cancer cell proliferation by SawPalmetto (Serenoa repens) extracts." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B29188969.

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20

Kilian, Gareth. "Development and testing of liposome encapsulated cyclic dipeptides." Thesis, Nelson Mandela Metropolitan University, 2011. http://hdl.handle.net/10948/1397.

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Cyclic dipeptides have been well characterized for their multitude of biological activities, including antimicrobial and anticancer activities. Cyclo(His-Gly) and cyclo(His-Ala) have also recently been shown to possess significant anticancer activity against a range of cell lines, despite the limitations of these two molecules with respect to their physicochemical properties. Low Log P results in poor cell permeability which can often be problematic for drugs with intracellular mechanisms of action. It can also results in poor biodistribution, and theoretical Log P values for cyclo(His-Gly) an
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21

Kwok, Hoi-shan, and 郭凱珊. "The comparison of biological properties of L- and D-enantiomeric antimicrobial peptides." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206507.

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Antibiotics have been used widely for the treatment of bacterial infections for over half a century. However, the emergence of resistance to antibiotics has aroused public health concern, leading to the development of antimicrobial peptides (AMPs) as potential alternative therapeutic agents against bacterial infections. AMPs are naturally found in many species and have important roles in our innate immune defense systems. AMPs are usually cationic amphipathic peptides with membrane destabilizing property. They have a relatively broad spectrum of antimicrobial activity and pathogens are less li
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22

Chaibva, Faith Anesu. "Development and assessment of an oxytocin parenteral dosage form prepared using pluronic ® F127." Thesis, Rhodes University, 2007. http://hdl.handle.net/10962/d1003225.

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23

Kritzinger, André Louis. "The medicinal chemistry of cyclo (Ser-Ser) and cyclo (Ser-Tyr)." Thesis, Nelson Mandela Metropolitan University, 2007. http://hdl.handle.net/10948/537.

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Cyclic dipeptides are widely used as models for larger peptides because of their simplicity and limited conformational freedom. Some cyclic dipeptides have been shown to produce antiviral, antibiotic and anti-tumour activity (Milne et al., 1998). In this study the cyclic dipeptides, cyclo(Ser-Ser) and cyclo(Ser-Tyr), were synthesised from their corresponding linear precursors using a modified phenolinduced cyclisation procedure. The phenol-induced cyclisation procedure resulted in good yields and purity of the cyclic dipeptides. Quantitative analysis and evaluation of the physicochemical prope
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24

Chan, Sze-yin, and 陳詩妍. "The effects of ganoderma extracts on immune cell subsets." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43781494.

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25

Khan, Tasmiyah. "Development of a novel, quantitative assay for determining the rate of activity of antimalarial drugs." Thesis, Rhodes University, 2013. http://hdl.handle.net/10962/d1001618.

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Malaria, caused by an intracellular Plasmodium parasite, remains a devastating disease, having claimed approximately 655 000 lives worldwide in 2010. The Medicines for Malaria Venture suggests a "single-dose radical cure" as the ideal malaria treatment since rapid clearance of blood-stage parasites and symptom relief improves patient compliance and limits drug resistance. Thus, novel antimalarials should be rapid-acting and assessing their rate of activity is critical to drug discovery. Traditional evaluation of this rate by morphological assessments is flawed by highly subjective, operator-sp
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26

Tjäderborn, Micaela. "Psychoactive prescription drug use disorders, misuse and abuse : Pharmacoepidemiological aspects." Doctoral thesis, Linköpings universitet, Avdelningen för läkemedelsforskning, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-130768.

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Background: There is a widespread and increasing use of psychoactive prescription drugs, such as opioid analgesics, anxiolytics, hypnotics and anti-epileptics, but their use is associated with a risk of drug use disorder, misuse and abuse. Today, these are globally recognized and emerging public health concerns. Aim: The aim of this thesis is to estimate the prevalence of psychoactive prescription drug (PPD) use disorders, misuse and abuse, and to investigate the association with some potential risk factors. Methods: A study using register data from forensic cause of death investigations inves
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27

Tanner, Delia Caroline. "Over-expression, purification and biochemical characterization of DOXP reductoisomerase and the rational design of novel anti-malarial drugs." Thesis, Rhodes University, 2004. http://hdl.handle.net/10962/d1003990.

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Malaria poses the greatest threat of all parasites to human life. Current vaccines and efficacious drugs are available however their use is limited due to toxicity, emergence of drug resistance, and cost. The discovery of an alternative pathway of isoprenoid biosynthesis, the non-mevalonate pathway, within the malarial parasite has resulted in development of novel anti-malarial drugs. 1-Deoxy-D-xylulose-5-phosphate (DOXP) reductoisomerase, the second enzyme in this pathway, is responsible for the synthesis of 2-C-methyl-D-erythritol 4-phosphate (MEP) in an intramolecular rearrangement step fol
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28

Sunkel, Vanessa Ann. "The investigation of novel marine microorganisms for the production of biologically active metabolites." Thesis, Rhodes University, 2009. http://hdl.handle.net/10962/d1004579.

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New drugs, particularly antibiotics, are urgently required to combat the increasing problem of antibiotic resistant human pathogens. Due to the scarcity of products available today, the pharmaceutical industry is now under pressure to reassess compounds derived from plants, soil and marine organisms. Pharmaceutical companies are showing renewed interest in marine biotechnology as the oceans represent a rich source of both biological and chemical diversity of novel molecular structures with anti-cancer, anti-inflammatory and antibiotic properties. Formerly unexplored locations, such as deep oce
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29

Perkonigg, Axel, Roselind Lieb, and Hans-Ulrich Wittchen. "Substance Use, Abuse and Dependence in Germany: A Review of Selected Epidemiological Data." Karger, 1998. https://tud.qucosa.de/id/qucosa%3A26266.

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To provide background information about previous findings about the prevalence of use, abuse and dependence of various substances (nicotine, alcohol, prescription and illicit drugs) findings of available epidemiological studies in Germany from the 1980s and 1990s are summarized and critically evaluated. Focusing on findings of substance use surveys in adolescents and young adults the review indicates: (a) a considerable number of large scale questionnaire surveys in general population samples documenting the frequency of use and patterns of use of most substances; (b) indications of increasing
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30

Ho, Yee-wa Eva, and 何綺華. "Effects of Ganoderma lucidum on rheumatoid synovial fibroblasts." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B29489933.

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31

Chia, Brian Cheng San. "Amphibian antimicrobial peptides : their structures and mechanisms of action : a thesis presented for the degree of Doctor of Philosophy." Title page, contents and abstract only, 2000. http://web4.library.adelaide.edu.au/theses/09PH/09phc532.pdf.

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Copy of author's previously published works inserted. Bibliography: leaves 183-220. Three antimicrobial peptides, maculatin 1.1, uperin 3.6 and caerin 4.1 have been isolated from the respective skin glands of the Australian amphibians Litoria genimaculata, Uperoleia mjobergii and Litoria caerulea. To gain a deeper insight into their mechanisms of action, three dimensional structural studies have been conducted using circular dichroism, two-dimensional nuclear resonance and computer modelling techniques. The role of central flexibility within antibiotic peptides in their interaction with bacter
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32

黃嫻 and Han Ann Wong. "Effects of 17{221}-estradiol on pressor response to phenylephrine and endothelin-1 in ovariectomized rats." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31969665.

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33

Yeung, King-yin Dennis, and 楊敬賢. "Effects of homocysteine and puerarin on coronary vasomotor responses." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B29293923.

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34

黑明燕 and Mingyan Hei. "Neuroprotection of tanshinone IIA to hypoxic-ischemic brain damage in neonatal SD rat." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B29797809.

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35

Pereira, Denize Duarte. "Determinação de Flunitrazepam e 7¬aminoflunitrazepam em soro por cromatografia líquida de alta eficiência acoplada à espectrometria de massa em tandem com a utilização de extração on line: aspecto forense." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/9/9141/tde-29012018-154046/.

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Atualmente os benzodiazepínicos constituem o grupo de fármacos de prescrição mais consumidas em todo o mundo. Além da utilização desta classe farmacológica como fármacos de abuso, mais recentemente seu uso está associado a uma nova cultura psicodélica emergente. O termo \"club drugs\" tem sido usado para descrever estes fármacos que levam a efeitos psicodélicos e euforizantes. Acresça-se a isto à preocupante utilização destas substâncias em situações de estupro e/ou assalto, as chamadas \"drug-facilitated sexual assault\", destacando-se o flunitrazepam. Devido às pequenas doses administradas e
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36

Wabnitz, Paul Andrew. "Chemistry and medical implications of novel amphibian peptides : a thesis submitted for the degree of Doctor of Philosophy /." Title page, contents and abstract only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09phw112.pdf.

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37

Kampen, Diane L. "The relationship between estrogen and memory in healthy postmenopausal women and women in the early stages of Alzheimer's disease." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=41108.

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The effects of exogenous estrogen administration on aspects of memory and cognition in women were examined in two studies. In Study 1, women receiving estrogen replacement therapy were compared to untreated women on four measures of verbal memory. Those receiving estrogen had significantly better scores on a measure of delayed memory for propositional material. In Study 2, women in the early stages of Alzheimer's Disease (AD) were administered either estrogen or placebo on a double-blind basis for six months. Women given estrogen showed improvement on a measure of verbal memory and spatial att
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38

Schwab, Anne Elisabeth. "The genetics of potential albendazole and ivermectin resistance in lymphatic filariae /." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=103006.

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A current initiative to eliminate lymphatic filariasis (LF), headed by the World Health Organization, aims to interrupt transmission of the disease through yearly community-wide treatment with the broad spectrum anthelmintic albendazole (ABZ), in combination with ivermectin (IVM) or diethylcarbamazine (DEC). Over the years, the use of both ABZ and IVM in the treatment of veterinary parasites has led to widespread anthelmintic resistance against these drugs. In this study, we genotyped microfilaria of Wuchereria bancrofti, a causative agent of LF, in order to detect the presence of mutations wh
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39

Gomes, Bruno Ramos. "O sentido do uso ritual da ayahuasca em trabalho voltado ao tratamento e recuperação da população em situação de rua em São Paulo." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/6/6136/tde-09092011-160114/.

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Esta pesquisa visa a compreender o uso ritual da ayahuasca (chamado de Daime pelos participantes) na recuperação de pessoas em situação de rua pela Unidade de Resgate Flor das Águas Padrinho Sebastião, grupo situado em São Paulo. A ayahuasca é um chá feito da mistura de algumas plantas amazônicas, mais comumente o jagube e a chacrona, utilizado de forma ritual por populações indígenas e mestiças há muito tempo, e que leva a uma alteração na experiência de si e do mundo em sua ingestão. Vem ganhando espaço na sociedade brasileira para diversos usos, tendo o uso ritual-religioso regulamentado no
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40

Bhatnagar, Barkha. "An examination of the effects of ivermectin on Brugia malayi adult worms /." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=100768.

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Brugia malayi is one of the causative agents of the disabling and disfiguring disease known as Lymphatic Filariasis (LF). This infection is a well-established ailment in tropical and subtropical countries and recently the drug ivermectin has been introduced for the LF control programs. Ivermectin (IVM) is an excellent microfilaricide, but is not markedly macrofilaricidal. However, it causes a long-lasting reduction in the production of new larvae by female worms, suggesting that adult stages are affected. However, the mechanism by which IVM produces such effect in the adult worm is not well un
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41

Neuwirth, April L. "The relationship between agitation level and psychotropic medication use in elderly dementia patients a research report submitted in partial fulfillment ... for the degree of Master of Science, Gerontological Nursing ... /." 1999. http://catalog.hathitrust.org/api/volumes/oclc/68901169.html.

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42

"Quantitative structure activity relationship (QSAR) of platinum drugs." 2006. http://library.cuhk.edu.hk/record=b5896517.

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Leung Chung Wai.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2006.<br>Includes bibliographical references (leaves 142-146).<br>Abstracts in English and Chinese.<br>ABSTRACT (ENGISH) --- p.iii<br>ABSTRACT (CHINESS) --- p.v<br>ACHKNOWLEDGEMENTS --- p.vii<br>TABLE OF CONTENTS --- p.viii<br>Chapter CHAPTER 1 --- Introduction and Background<br>Chapter 1.1 --- Introduction of Platinum Drugs --- p.1<br>Chapter 1.2 --- Mechanism of Action of Cisplatin --- p.3<br>Chapter 1.3 --- Structure-Activity Relationships of the Platinum Drug 、 --- p.4<br>Chapter 1.4 --- QS AR Parameters --- p.9
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43

"Quantitative structure activity and property study of platinum drugs." Thesis, 2008. http://library.cuhk.edu.hk/record=b6074538.

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Chemical hardness (eta), calculated by density functional theory (DFT), was firstly used as one of the chemical reactivity descriptors to set up the one descriptor 2D-QSAR model of platinum drugs. In this simple but promising model, the antitumour activities (log GI50) evaluated by National Cancer Institute (NCI) of structure-based groups containing normal sp 3 nitrogen and R,R-diamminecyclohexane (R,R-DACH) as the ligand showed good correlation. It was also demonstrated that silane and stereoisomers of DACH groups showed special patterns. This study also made use of the COMPARE program from N
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44

Hull, Ruth Heather. "A group analysis evaluation of the selected psychoactive plant remedies in terms of known materia medica." Thesis, 2016. http://hdl.handle.net/10321/1771.

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Submitted in partial compliance with the requirements of the Master’s Degree in Technology: Homoeopathy, Durban University of Technology, Durban, South Africa, 2016.<br>There are now several thousand remedies available to a homoeopath and this number is continually increasing with the increase in homoeopathic research and provings. This growing wealth of data does, however, make choosing a homoeopathic remedy difficult and some homoeopaths argue that the essence of homoeopathic remedies are being lost in this excess of data. In an attempt to more accurately see a remedy’s ‘picture’ and gain
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"Antidepressant-like effects of total glycosides of peony and its possible mechanisms." Thesis, 2010. http://library.cuhk.edu.hk/record=b6074989.

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Finally, the neuroprotective effects of TGP against corticosterone-induced neurotoxicity in rat pheochromocytoma (PC12) cells, an in vitro experimental model of depression were studied. The results showed TGP treatment dose-dependently protected the cells against corticosterone-induced toxicity. The cytoprotection afforded by TGP treatment was shown to be associated with an enhanced antioxidant activity, and increased expressions of neurotrophins including brain-derived neurotrophic factor, nerve growth factor and neurotrophin-3.<br>Secondly, the antidepressant-like effect of TGP was evaluated
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46

"Study on the effective contents of trace elements in Chinese mineral drugs." 1998. http://library.cuhk.edu.hk/record=b5889668.

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by Leung Ho-yin.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 1998.<br>Includes bibliographical references.<br>Abstract also in Chinese.<br>Acknowledgement --- p.i<br>Abstract --- p.ii<br>Table of Contents --- p.iv<br>List of Tables and Figures --- p.v<br>Chapter Chapter 1 --- Introduction --- p.1<br>Chapter Chapter 2 --- Methodology --- p.12<br>Chapter Chapter 3 --- Experimental --- p.17<br>Chapter 3.1 --- Sample Collection --- p.17<br>Chapter 3.2 --- Preliminary Sample Treatment --- p.18<br>Chapter 3.3 --- Dissolution Test Apparatus --- p.18<br>Chapter 3.4 --- Reagents ---
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47

"Analytical and pharmacokinetic studies of the main chemical ingredients of rhizoma chuanxiong." Thesis, 2005. http://library.cuhk.edu.hk/record=b6074230.

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and senkyunolide A were found as the three major compounds in all herbal samples investigated. In addition, great variations in both total and individual content of each of the ten main components investigated were observed in samples of different origins and those collected from a GAP developing base in the same or different years, suggesting the necessity of a thorough quality control for Rhizoma Chuanxiong.<br>Extraction of the main ingredients from Rhizoma Chuanxiong by supercritical fluid extraction using CO2 was investigated. An appropriate SCFE method for Chuanxiong was developed with t
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48

Romano, Joseph Daniel. "Computational Toxinology." Thesis, 2019. https://doi.org/10.7916/d8-9248-7e68.

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Venoms are complex mixtures of biological macromolecules and other compounds that are used for predatory and defensive purposes by hundreds of thousands of known species worldwide. Throughout human history, venoms and venom components have been used to treat a vast array of illnesses, causing them to be of great clinical, economic, and academic interest to the drug discovery and toxinology communities. In spite of major computational advances that facilitate data-driven drug discovery, most therapeutic venom effects are still discovered via tedious trial-and-error, or simply by accident. In th
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"Pharmacological and chemical investigations into bulbus fritillariae." 2000. http://library.cuhk.edu.hk/record=b6073240.

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Chan Shun Wan.<br>"August 2000."<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2000.<br>Includes bibliographical references (p. 217-235).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Mode of access: World Wide Web.<br>Abstracts in English and Chinese.
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Borovic, Sladana. "Copper complexes as therapeutic drugs: use of analytical / spectroscopic methods for the evaluation of their transport in blood." Master's thesis, 2012. http://hdl.handle.net/10400.1/10635.

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Dissertação de Mestrado, Qualidade em Análises, Faculdade de Ciências e Tecnologia, Universidade do Algarve. Centro de Química Estrutural Complexo I, Instituto Superior Técnico, 2012<br>Os complexos de cobre(II) têm sido muito estudados, nomeadamente devido à sua actividade anticancerígena e outros efeitos. As interacções dos complexos de Cu com proteínas do soro sanguíneo humano são importantes para a sua biodisponibilidade e características farmacocinéticas. É importante compreender a natureza das interacções do Cu e dos seus complexos com as proteínas do soro, nomeadamente com a albumina,
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