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1

Soyka, Michael. "Substance misuse, psychiatric disorder and violent and disturbed behaviour." British Journal of Psychiatry 176, no. 4 (2000): 345–50. http://dx.doi.org/10.1192/bjp.176.4.345.

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BackgroundEpidemiological studies suggest schizophrenia and substance misuse to be associated with a higher rate of violence and crime.AimsThe literature was evaluated to assess whether people with schizophrenia who use substances have an increased risk for violence and disturbed behaviour.MethodA detailed Medline analysis was performed and relevant studies were reviewed.ResultsA large number of studies have linked substance misuse in schizophrenia with male gender, high incidence of homelessness, more pronounced psychotic symptoms, non-adherence with medication, poor prognosis, violence and a
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2

Maria, Bonea, Kadar Iulia-Larisa, Delcea Cristian, Mălina Horgoș Bianca, and Angela Crișan Cătălina. "BRAIN. Broad Research in Artificial Intelligence and Neuroscience - Aggressivity in Schizophrenia: The Risk and Confounders in a Romanian Setting." BRAIN. Broad Research in Artificial Intelligence and Neuroscience 15, no. 4 (2024): 144–53. https://doi.org/10.70594/brain/15.4/11.

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There is an increased stigma in Romania regarding schizophrenia patients, who are thought to be violent and dangerous. However, there is little research on this topic that analyzes the exact risk of aggressive behavior, especially considering the high prevalence of alcohol and substance abuse, conditions also associated with a potential risk of violent behavior. The objectives of this study were to compare aggressivity levels between patients with schizophrenia admitted to an emergency hospital and healthy individuals and to find possible risk factors. This case-control study, matched for age
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Cheung, Peter, and Isaac Schweitzer. "Correlates of Aggressive Behaviour in Schizophrenia: An Overview." Australian & New Zealand Journal of Psychiatry 32, no. 3 (1998): 400–409. http://dx.doi.org/10.3109/00048679809065534.

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Objective: This review aims to critically evaluate the reported biological, psychological and social correlates of aggression in schizophrenia and to delineate those correlates which could be of use clinically and those which require further research. Method: The literature from 1974–1996 was searched using Psychlit and supplemented by suggestions from senior members of the authors' Department. Results: Past history of aggression, psychopathology, extrapyramidal side effects of neuroleptic medications, substance abuse, reduced serotonin function, antisocial and impulsive personality traits, ne
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Dr., Vasave Tejeswini R., Shah Hetvi D. Dr., Gawande Sushil D. Dr., and Bhave Sudhir H. Dr. "Assessment of Aggression in Psychiatric Indoor Patients using SOAS-RE Scale." Sarcouncil journal of Medical Sciences 5, no. 4 (2025): 8–12. https://doi.org/10.5281/zenodo.15380871.

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<strong>Introduction</strong>- Aggressive behaviour in psychiatry ward is fairly common and often threatens the safety of patient, relatives and staff. It determines the duration of hospitalization, burden on the caregivers, outcome and prognosis of illness and increases the usage of coercive measures like seclusion and restraint. <strong>Aim</strong>-To study the prevalence of aggression in various psychiatric disorders and correlation of socio-demographic factors with the severity of aggression. <strong>Method</strong>-A retrospective record-based study design in the psychiatry indoor settin
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Bonea, Maria, Iulia Larisa Kadar, Cristian Delcea, Bianca Malina Horgoș, and Catalina Angela Crisan. "Aggressivity in Schizophrenia: The Risk and Confounders in a Romanian Setting." BRAIN. Broad Research in Artificial Intelligence and Neuroscience 15, no. 4 (2024): 144. https://doi.org/10.70594/brain/15.4/11.

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&lt;p dir="ltr"&gt;&lt;span&gt;There is an increased stigma in Romania regarding schizophrenia patients, who are thought to be violent and dangerous. However, there is little research on this topic that analyzes the exact risk of aggressive behavior, especially considering the high prevalence of alcohol and substance abuse, conditions also associated with a potential risk of violent behavior. The objectives of this study were to compare aggressivity levels between patients with schizophrenia admitted to an emergency hospital and healthy individuals and to find possible risk factors. This case-
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Lauber, Christoph, Adrian Eichenberger, Peter Luginbühl, Christian Keller, and Wulf Rössler. "Determinants of burden in caregivers of patients with exacerbating schizophrenia." European Psychiatry 18, no. 6 (2003): 285–89. http://dx.doi.org/10.1016/j.eurpsy.2003.06.004.

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AbstractPurposeRestriction in involuntary hospital admission and reduced lengths of inpatient stay increase burden on relatives of individuals with schizophrenia. This study aims at assessing the relationship between caregiver burden and behavioural disturbances of the affected, e.g. threats, nuisances, but also substance use and aggression. Two weeks before the last hospitalisation of the affected are considered as being the most burdensome period for relatives.Subjects and methodsSixty-four relatives of schizophrenic patients were assessed by the semi-structured “Interview for Measuring the
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Khouadja, S., S. Younes, S. Chatti, R. Ben Soussia, L. Zarrouk, and M. Nasr. "The acting out in patients with Schizophrenia examined in a forensic psychiatric assessment." European Psychiatry 41, S1 (2017): S591. http://dx.doi.org/10.1016/j.eurpsy.2017.01.906.

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IntroductionMany studies have shown that schizophrenic patients are responsible for the highest rates of violence among all the mentally ill patients.Aims of the studyDescribe the socio-demographic and clinical characteristics of patients with schizophrenia examined in a forensic psychiatric assessment and identify the risk factors of violence in these patients.MethodologyA retrospective study carried out in the psychiatric department of university hospital of Mahdia during fifteen years involving 40 patients with schizophrenia examined in a forensic psychiatric assessment following a forensic
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Jones, Mackenzie T., and Philip D. Harvey. "Neurocognition and social cognition training as treatments for violence and aggression in people with severe mental illness." CNS Spectrums 25, no. 2 (2019): 145–53. http://dx.doi.org/10.1017/s1092852919001214.

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Aggressive and violent behavior, including both verbal and physical aggression, have considerable adverse consequences for people with schizophrenia. There are several potential causes of violent behavior on the part of people with severe mental illness, which include intellectual impairments, cognitive and social-cognitive deficits, skills deficits, substance abuse, antisocial features, and specific psychotic features. This review explores the interventions that have been tested to this date. Computerized Cognitive Training (CCT) or Computerized Social-Cognitive Training (CSCT) have been asso
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van Dongen, Josanne D. M., Nicole M. L. Buck, and Hjalmar J. C. van Marle. "Positive symptoms, substance use, and psychopathic traits as predictors of aggression in persons with a schizophrenia disorder." Psychiatry Research 237 (March 2016): 109–13. http://dx.doi.org/10.1016/j.psychres.2016.01.068.

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10

Žgavec, Nace, and Blanka Kores Plesničar. "A Comparison of Incidence of Patient Aggression in the University Psychiatric Clinic Ljubljana and at the Department of Psychiatry of the University Medical Centre Maribor." Acta Medico-Biotechnica 9, no. 1 (2021): 18–25. http://dx.doi.org/10.18690/actabiomed.128.

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Purpose: Management of aggressive behaviour in patients with psychiatric diagnoses presents a challenge and burden for health staff. The present study compared two psychiatric institutions (the Department of Psychiatry of the University Medical Centre Maribor and the University Psychiatric Clinic Ljubljana) in terms of frequency and consequences of patient aggression. We compared frequencies of aggression between male and female patients, patients diagnosed with schizophrenia and other diagnoses, previously aggressive patients and patients who were aggressive for the first time. We also compar
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Strassnig, Martin T., Vanessa Nascimento, Elizabeth Deckler, and Philip D. Harvey. "Pharmacological treatment of violence in schizophrenia." CNS Spectrums 25, no. 2 (2019): 207–15. http://dx.doi.org/10.1017/s1092852919001226.

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Chronic aggression and violence in schizophrenia are rare, but receive disproportionate negative media coverage. This contributes to the stigma of mental illness and reduces accessibility to mental health services. Substance Use Disorders (SUD), antisocial behavior, non-adherence and recidivism are known risk factors for violence. Treatment with antipsychotic medication can reduce violence. Aside from clozapine, long-acting injectable antipsychotics (LAI) appear to be superior to oral antipsychotics for preventing violence, addressing adherence and recidivism. LAI also facilitate the implement
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Selivanov, G., and N. Bokhan. "Comorbidity of mental disorders in synthetic cannabinoids abuse: clinical dynamics, behavior, adaptation." European Psychiatry 67, S1 (2024): S477—S478. http://dx.doi.org/10.1192/j.eurpsy.2024.991.

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IntroductionThe study of the phenomenon of deformation of mental disorders, clinical dynamics, behaviors, and adaptations in case of abuse of synthetic cannabinoids is of relevance.ObjectivesTo study the phenomenon of deformation of mental disorders, clinical dynamics, behaviors, and adaptations in case of abuse of synthetic cannabinoidsMethodsCatamnestic, clinical-psychopathological methods (PANS, SANS, CGI, MMPI, CGI, STAI, LSI, TPA, ICD-10), statistical (Python 3.11.0).Results291 men (age from 18 to 35 years) were examined: 240 - F12.2xx, of which 98 - F60.xx-F62.xx, 142 - F20.xx and 51 - F
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Ostinelli, Edoardo G., Armando D’Agostino, Farhad Shokraneh, Georgia Salanti, and Toshi A. Furukawa. "Acute interventions for aggression and agitation in psychosis: study protocol for a systematic review and network meta-analysis." BMJ Open 9, no. 10 (2019): e032726. http://dx.doi.org/10.1136/bmjopen-2019-032726.

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IntroductionIndividuals with psychosis may access emergency services due to aggression and agitation. When the de-escalation technique fails to achieve tranquillisation, several pharmacological options are available. However, evidence on which intervention to prefer in terms of efficacy and tolerability to achieve resolution of the acute episode (ie, rapid tranquillisation) of aggression and agitation is currently fragmentary.Methods and analysisWe will include all randomised controlled trials comparing drugs or drug combinations or placebo for aggression or agitation episodes in adult individ
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14

Caley, Charles F. "The Pharmacotherapy of Human Aggression: A Review." Journal of Pharmacy Practice 9, no. 2 (1996): 133–43. http://dx.doi.org/10.1177/089719009600900210.

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Aggression is a common treatment problem that may be associated with several disorders including schizophrenia, schizoaffective disorder, acute mania/bipolar disorder, personality disorders, substance abuse disorders, medical disorders, neurological disorders, and medication misadventures. Aggression is not a linear entity, it is a multidimensional problem influenced by a patient's environment and biological, psychological, and/or neurological status. It follows that if one has a multidimensional treatment problem, then a compre hensive treatment plan must be used to achieve optimal management
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15

Shoval, G., A. Weizman, and G. Zalsman. "Substance Use, Suicidality and Adolescent-onset Schizoprenia - an Israeli Ten-year Retrospective Study." European Psychiatry 24, S1 (2009): 1. http://dx.doi.org/10.1016/s0924-9338(09)70421-3.

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Objective:To investigate the link between the use of specific types of substances and suicidality in adolescent inpatients with schizophrenia and schizoaffective disorder.Methods:We performed a ten-year naturalistic retrospective study of 178 adolescent inpatients diagnosed as suffering from either schizophrenia or schizoaffective disorder. A comparison was made between the suicide-attempting adolescent inpatients and the non-attempting subjects, by the use of specific types of substances, measurements of psychotic, depressive and aggressive symptoms and clinical data reported during their hos
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Thiagarajan, Siroshini K., Siew Ying Mok, Satoshi Ogawa, Ishwar S. Parhar, and Pek Yee Tang. "Receptor-Mediated AKT/PI3K Signalling and Behavioural Alterations in Zebrafish Larvae Reveal Association between Schizophrenia and Opioid Use Disorder." International Journal of Molecular Sciences 23, no. 9 (2022): 4715. http://dx.doi.org/10.3390/ijms23094715.

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The link between substance abuse and the development of schizophrenia remains elusive. In this study, we assessed the molecular and behavioural alterations associated with schizophrenia, opioid addiction, and opioid withdrawal using zebrafish as a biological model. Larvae of 2 days post fertilization (dpf) were exposed to domperidone (DMP), a dopamine-D2 dopamine D2 receptor antagonist, and morphine for 3 days and 10 days, respectively. MK801, an N-methyl-D-aspartate (NMDA) receptor antagonist, served as a positive control to mimic schizophrenia-like behaviour. The withdrawal syndrome was asse
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Thiagarajan, Siroshini K., Siew Ying Mok, Satoshi Ogawa, Ishwar S. Parhar, and Pek Yee Tang. "Receptor-Mediated AKT/PI3K Signalling and Behavioural Alterations in Zebrafish Larvae Reveal Association between Schizophrenia and Opioid Use Disorder." International Journal of Molecular Sciences 23, no. 9 (2022): 4715. http://dx.doi.org/10.3390/ijms23094715.

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The link between substance abuse and the development of schizophrenia remains elusive. In this study, we assessed the molecular and behavioural alterations associated with schizophrenia, opioid addiction, and opioid withdrawal using zebrafish as a biological model. Larvae of 2 days post fertilization (dpf) were exposed to domperidone (DMP), a dopamine-D2 dopamine D2 receptor antagonist, and morphine for 3 days and 10 days, respectively. MK801, an N-methyl-D-aspartate (NMDA) receptor antagonist, served as a positive control to mimic schizophrenia-like behaviour. The withdrawal syndrome was asse
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18

Markova, E. V., E. V. Serenko, and M. A. Knyazheva. "AGGRESSIVE BEHAVIOR CORRECTION BY THE TRANSPLANTATION OF IN VITRO MODULATED IMMUNE CELLS." Medical Immunology (Russia) 23, no. 4 (2021): 693–98. http://dx.doi.org/10.15789/1563-0625-abc-2263.

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Aggression is a serious biomedical problem associated with a high percentage of patients and a lack of selective corrective agents. The most frequent increase in aggressiveness occurs in patients with depressive disorders, schizophrenia, reactive psychoses and adjustment disorders, which are known to be characterized by immunological dysfunction. Antipsychotics are widely used in the correction of psychomotor agitation; the antipsychotic effect of these drugs is manifested in the achievement of a sedative effect. However, like other psychoactive substances, they have a number of side effects t
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Chiappini, Stefania, Clara Cavallotto, Alessio Mosca, et al. "Investigating the Effectiveness of Brexpiprazole in Subjects with Schizophrenia Spectrum Illness and Co-Occurring Substance Use Disorder: A Prospective, Multicentric, Real-World Study." Pharmaceuticals 17, no. 4 (2024): 535. http://dx.doi.org/10.3390/ph17040535.

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Background: Dual disorders (DDs) involve the coexistence of a substance use disorder (SUD) with another mental illness, often from the psychotic and affective categories. They are quite common in clinical practice and present significant challenges for both diagnosis and treatment. This study explores the effectiveness of brexpiprazole, a third-generation antipsychotic, in an Italian sample of individuals diagnosed with schizophrenia spectrum disorder and a comorbid SUD. Methods: Twenty-four patients, diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Editi
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MOTOJESI, MODUPE, ISMAIL ADESINA, OLUWASIKEMI ALALADE, et al. "Effectiveness of oral tranquilization in the management of aggression in a specialist psychiatric emergency setting." Nigerian Journal of Psychiatry 22, no. 2 (2024): 12. https://doi.org/10.5455/njp.204655.

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Background: Emergencies in psychiatry have a peculiar pattern of presentation, with florid aggression and agitation being very common. Such presentations may pose threats to the patients themselves, those around them, and the environment. The primary goal of intervention is to ensure the safety of the patient, personnel, and surroundings. Aim: This study aimed to determine the effectiveness of oral medications—chlorpromazine, olanzapine, and diazepam—in calming patients during episodes of aggression. Methods: This was a pragmatic randomized experimental study conducted at the emergency psychia
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Jepsen, J. R. M., J. Rydkjaer, B. Fagerlund, et al. "Overlapping and disease specific trait, response, and reflection impulsivity in adolescents with first-episode schizophrenia spectrum disorders or attention-deficit/hyperactivity disorder." Psychological Medicine 48, no. 4 (2017): 604–16. http://dx.doi.org/10.1017/s0033291717001921.

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BackgroundSchizophrenia and attention-deficit/hyperactivity disorder (ADHD) are developmental disorders with shared clinical characteristics such as cognitive impairments and impulsivity. Impulsivity is a core feature of ADHD and an important factor in aggression, violence, and substance use in schizophrenia. Based on the hypothesis that schizophrenia and ADHD represent a continuum of neurodevelopmental impairments, the aim was to identify overlapping and disease specific forms of impulsivity.MethodsAdolescents between 12 and 17 years of age were assessed with the Schedule for Affective Disord
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Sengstock, Brian, and Janet Curtis. "Excited delirium syndrome." Journal of Paramedic Practice 15, no. 8 (2023): 1–8. http://dx.doi.org/10.12968/jpar.2023.15.8.cpd1.

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Mental health calls make up a large proportion of ambulance workloads, with paramedics responding to a wide range of presentations such as anxiety, depression, bipolar disorder, schizophrenia, and excited delirium syndrome. Excited delirium syndrome is an increasingly common presentation, characterised by extreme agitation and aggression in a patient with an altered mental status. Excited delirium is a potentially life-threatening condition, with generally non-specific symptoms. Common triggers of excited delirium syndrome are acute drug use, psychiatric illness, or abrupt cessation of antipsy
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Chiappini, Stefania, *Clara Cavallotto, Giacomo D'andrea, et al. "EXAMINING LURASIDONE EFFICACY IN SCHIZOPHRENIC PATIENTS WITH COMORBID ALCOHOL AND SUBSTANCE USE DISORDER: A MULTICENTRIC PROSPECTIVE INVESTIGATION." International Journal of Neuropsychopharmacology 28, Supplement_1 (2025): i91—i92. https://doi.org/10.1093/ijnp/pyae059.157.

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Abstract Background Alcohol/Substance Use Disorder (AUD/SUD) among schizophrenic patient represent a common and problematic co-occurrence, with a rate of comorbidity assessed between 40% and 70%, especially in young patients at the onset of their disorder (1-2). Comorbid patients are usually difficult to treat: they show a very low level of compliance, and are frequently exposed to drop-out and lack of efficacy for the available antipsychotic drugs leading to worsened clinical outcomes and increased difficulty in treatment (3-4). Aims &amp; Objectives to evaluate the effectiveness and safety o
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Benzahra, S., A. Karara, H. Nafiaa, and A. Ouanass. "SCHIZOPHRENIA AND EPILEPSY: WHAT LINKS BETWEEN? ARRAZI HOSPITAL EXPERIENCE ABOUT 56 CASES." International Journal of Advanced Research 9, no. 08 (2021): 293–99. http://dx.doi.org/10.21474/ijar01/13263.

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Background: Given the higher incidence of psychotic disorders in patients with epilepsy, several neurologists and psychiatrists have attempted to explain this controversial comorbidity. Thus, several hypotheses have been put forward but no link has been established with certainty until today. Objectives: The aim of our work is to draw up a socio-demographic and psychopathological profile of patients with schizophrenia-epilepsy comorbidity as well as to assess the risk of suicide, the management, the reasons for admission and the length of hospitalization. Methodology: we conducted a retrospect
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Nennicioglu, Y., H. Kaya, S. Eraybar, S. Atmaca, O. Gorukmez, and E. Armagan. "An investigation of the COMT gene Val158Met polymorphism in patients admitted to the emergency department because of synthetic cannabinoid use." Balkan Journal of Medical Genetics 23, no. 1 (2020): 63–68. http://dx.doi.org/10.2478/bjmg-2020-0010.

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AbstractCatechol-O-methyl transferase (COMT) enzyme has a role in the inactivation of catecholamine neurotransmitters. Functional polymorphism in the COMT gene has been reported to play an important role in schizophrenia, bipolar affective disorder, aggressive and antisocial behavior, suicide attempts and the pathogenesis of Parkinson’s disease. In this study, we aimed to investigate the effect of the Vall58Met polymorphism of the COMT gene on substance use, and treatment history in patients with synthetic cannabinoid (SC) intoxication. The COMT enzyme Val158Met polymorphisms from DNA of 49 pa
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Satisha, Shantala, and Emily Pettifor. "A Survey of Referrals to Psychiatric Intensive Care Unit (PICU): Patient Characteristics and Outcome." BJPsych Open 10, S1 (2024): S202. http://dx.doi.org/10.1192/bjo.2024.505.

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AimsThe project aims to evaluate the referrals from North Kent for admission to our PICU from April to November 2021.Hypothesis:There are very few surveys of PICU referrals. We expect more referrals for younger men with psychotic illnesses and comorbid diagnoses; to be for aggressive behaviours; and most will be admitted to acute wards with ongoing support from the PICU liaison team.BackgroundOur PICU services in the trust include one 12-bedded male PICU, 5 contracted female PICU beds and the PICU liaison service. PICU liaison team ‘gatekeep’ the PICU beds for patients meeting the admission cr
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Galindo, L., M. Grifell, E. J. Peréz, et al. "Are there more mechanical restraint in patients admitted for substance use disorder?" European Psychiatry 33, S1 (2016): S297. http://dx.doi.org/10.1016/j.eurpsy.2016.01.1013.

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Introduction and objectivesMechanical restraint is a therapeutic procedure commonly applied in acute units in response to psychomotor agitation. Its frequency is between 21 and 59% of patients admitted. These patients represent a risk to both themselves and for health workers. There is a myth that patients with substance use disorder (SUD) are more aggressive and require more forceful measures. There are not clinical studies that compared if there are differences of the frequency of mechanical restrain in patients with SUD.The aim of this study is to explore the differences of frequency of mec
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Steixner-Kumar, Agnes, Jan Seidel, Vinicius Daguano Gastaldi, Martin Begemann, and Hannelore Ehrenreich. "T81. MULTIPLE DRUG USE IN SCHIZOPHRENIA - THE ROLE OF EARLY ENVIRONMENTAL RISK ACCUMULATION AND GENETIC PREDISPOSITION." Schizophrenia Bulletin 46, Supplement_1 (2020): S262—S263. http://dx.doi.org/10.1093/schbul/sbaa029.641.

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Abstract Background Drug (ab)use and substance use disorders are frequently observed in patients with psychiatric illness, but the underlying causes remain widely unknown. A number of environmental risk factors have been proposed to affect the use of one or multiple drugs in the general population and adolescents. Whereas most previous studies focused on the influence of single risk factors on the use of one or a few selected drugs, the effect of accumulated environmental risk in early life on multiple drug use remains to be studied. Similarly, evidence on genetic susceptibility to the (ab)use
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Kingdon, D. "FC19-03 - Advances in cognitive behaviour therapy for psychosis." European Psychiatry 26, S2 (2011): 1917. http://dx.doi.org/10.1016/s0924-9338(11)73621-5.

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IntroductionCBT for psychosis has been developed over the past two decades and is now recommended by most clinical guidelines for schizophrenia internationally.Aims &amp; objectivesTo provide an up-date on advances and controversies in CBT for psychosis.MethodEvidence from recent meta-analyses (including Lynch et al, 2010) and randomised controlled trials will be reviewed. These have generally demonstrated effectiveness in early and treatment-resistant schizophrenia of CBT, and other specific indications, e.g. co-morbid substance misuse, aggressive behaviour, command hallucinations. Treatment
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Mellouli, A., N. Charfi, I. Gassara, et al. "Risk assessment of agressive behavior in schizophrenia and schizoaffective disorder : a cross-sectional study." European Psychiatry 66, S1 (2023): S1047—S1048. http://dx.doi.org/10.1192/j.eurpsy.2023.2223.

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IntroductionPsychotic disorders have been consistently associated with aggressive behaviors. Psychiatrists are frequently asked to perform assessment regarding potentially aggressive patients. Thus, many psychometric instruments can be useful for identifying the risk of violence and thereby offering appropriate treatment for these individuals.ObjectivesThe aims of this study were to assess the risk of agressive behavior in inpatients with schizophrenia or schizoaffective disorder and to determine its correlates.MethodsUsing face-to-face interviews, inpatients diagnosed with schizophrenia or sc
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Hodgins, Sheilagh, Jari Tiihonen, and Deborah Ross. "The consequences of Conduct Disorder for males who develop schizophrenia: Associations with criminality, aggressive behavior, substance use, and psychiatric services." Schizophrenia Research 78, no. 2-3 (2005): 323–35. http://dx.doi.org/10.1016/j.schres.2005.05.021.

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Bikbov, M. M., E. L. Usubov, and I. I. Kandarova. "Quality of Life Change in Patients with Keratoconus. Literature Review." Ophthalmology in Russia 19, no. 4 (2022): 727–33. http://dx.doi.org/10.18008/1816-5095-2022-4-727-733.

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In recent years, ophthalmologists have paid great attention to keratoconus, as the disease is socially significant and affects the young working-age population. According to the literature and in clinical practice, it was found that patients with keratoconus have similar character traits, which are manifested to a greater or lesser extent in each patient. According to a number of authors, these patients have less adaptability, passive aggression, and paranoia. In addition, there is a tendency to disorganization of thinking, substance abuse and anxiety. The article considers clinical cases of A
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Voulgaris, A. "Aggressive behavior and severe mental disorders in Prison psychiatry." European Psychiatry 66, S1 (2023): S535. http://dx.doi.org/10.1192/j.eurpsy.2023.1132.

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IntroductionAggressive behavior can be understood as a compelx and social phenomenon. A number of studies have shown that the risk of aggressive behavior is increased for patients with severe mental disorders such as schizophrenia. Although specialized forensic institutions exist in many countries, most offenders with mental disorders are still found in prison settings what corresponds to international literature suggesting an increased prevalence of mental disorders in prison inmates. Still, data on the specific characteristics of patients demonstrating aggressive behavior in medical and ment
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Pawar, Jeevan Atmaram. "Study of Obsessive Compulsive Disorder in Adult Females of Maharashtra population." Indian Journal of Medical and Health Sciences 5, no. 2 (2018): 69–72. http://dx.doi.org/10.21088/ijmhs.2347.9981.5218.2.

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Out of 450 adults females having the symptoms of OCD 38 (8.4%) were diagnosed as OCD. Among these 9 (23%) had obsession 11 (28%) had compulsion and 18 (47%) patient had mixed OCD clinical presentation. The family history of OCD Patients was 14 (36%) were disturbed family, 8 (21%) were divorcee, 13 (34%) were unmarried, 3 (7.8%) were widow. In the obsession study, aggressive patients were 2 (16.6%), sexual obsession were 3 (25%), religious obsession were 2 (16.6%), hoarding obsession were 2 (16.6%), contamination obsession were 2 (16.6%), somatic obsession were 1 (8.3%). Patients presenting wit
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Volavka, Jan. "Aggression in Psychoses." Advances in Psychiatry 2014 (February 12, 2014): 1–20. http://dx.doi.org/10.1155/2014/196281.

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Most individuals diagnosed with a mental illness are not violent, but some mentally ill patients commit violent acts. PubMed database was searched for articles published between 1980 and November 2013 using the combination of key words “schizophrenia” or “bipolar disorder” with “aggression” or “violence.” In comparison with the general population, there is approximately a twofold increase of risk of violence in schizophrenia without substance abuse comorbidity and ninefold with such comorbidity. The risk in bipolar disorder is at least as high as in schizophrenia. Most of the violence in bipol
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Doran, Neal, Susan E. Luczak, Nicole Bekman, Igor Koutsenok, and Sandra A. Brown. "Adolescent Substance Use and Aggression." Criminal Justice and Behavior 39, no. 6 (2012): 748–69. http://dx.doi.org/10.1177/0093854812437022.

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Substance use disorders (SUDs) in youth are strongly associated with aggression, delinquency, and involvement with the juvenile justice and mental health systems. This article reviews the relationship between aggression and SUDs and discusses evidence-based approaches to assessment and intervention, with a focus on youth in secure settings. While evidence indicates etiological overlap, SUDs also confer risk for aggression and delinquent behavior. SUDs and aggression are each influenced by executive functions that develop as youth transition toward adult roles. Additionally, the effects of subs
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Chen, Meng-Jinn, Brenda A. Miller, Joel W. Grube, and Elizabeth D. Waiters. "Music, Substance Use, and Aggression." Journal of Studies on Alcohol 67, no. 3 (2006): 373–81. http://dx.doi.org/10.15288/jsa.2006.67.373.

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Lalli, Naveen, Olabisitaiye Abu, Safyan Tariq, Vijay Perla, and Nilamadhab Kar. "Evaluating Current Practice of Prescribing as Required Medications for Psychiatric Inpatients." BJPsych Open 10, S1 (2024): S193—S194. http://dx.doi.org/10.1192/bjo.2024.486.

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AimsPro re nata (PRN) medications are commonly prescribed for psychiatric patients on admission, often at maximum daily dose (MaxD). We intended to evaluate prescribing patterns for PRN medications, their MaxD, and rationale, specifically in the first seven days in the hospital, along with any concerns of associated physical illnesses.MethodsAll the inpatients on a specific date, admitted to adult and old age wards of a general psychiatric hospital, for at least 7 days, were recruited for this service evaluation. Data regarding the prescribing of promethazine, lorazepam, zopiclone as PRN, pati
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Lee, Reagan, Oscar Han, and Jingjing Wang. "Rapid Review: Ascertaining the Type of Potentially Life-Threatening Cardiovascular Events and Eventual Cardiovascular Mortality From Antipsychotic Use in Clinical Practice." BJPsych Open 10, S1 (2024): S55. http://dx.doi.org/10.1192/bjo.2024.190.

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AimsAccording to the World Health Organization (WHO), there has been a 13% increase in mental health and substance abuse disorders within the last decade. Typical and atypical antipsychotics are the most common treatment mechanisms for mental health-related disorders such as schizophrenia, depression with psychotic symptoms and bipolar disorders. However, antipsychotic usage is associated with more than a 50% increase in CVD such as ischaemic heart disease, resulting in cardiovascular-related mortality.This review aims to investigate the most common type of cardiovascular event causing mortali
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Hamdi, Nayla R., and Raymond A. Knight. "The Relationships of Perpetrator and Victim Substance Use to the Sexual Aggression of Rapists and Child Molesters." Sexual Abuse 24, no. 4 (2011): 307–27. http://dx.doi.org/10.1177/1079063211420450.

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Objective: This study investigated substance use in rape and child molestation. We hypothesized that perpetrator substance use would be associated with a greater increase in rapists’ aggression in sexual crimes compared with that of child molesters. We also predicted that victim substance use would be negatively related to both rapists and child molesters’ aggression in sexual crimes. Method: The sample included 245 male rapists and 273 male child molesters who had been evaluated at the Massachusetts Treatment Center (MTC) between 1959 and 1991 for potential civil commitment. Data were obtaine
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Wang, Grace Y., and Mark Crook-Rumsey. "Aggression in substance use treatment seekers." Personality and Individual Differences 180 (October 2021): 110997. http://dx.doi.org/10.1016/j.paid.2021.110997.

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Margolin, Gayla, Michelle C. Ramos, Brian R. Baucom, Diana C. Bennett, and Elyse L. Guran. "Substance Use, Aggression Perpetration, and Victimization." Journal of Interpersonal Violence 28, no. 14 (2013): 2849–72. http://dx.doi.org/10.1177/0886260513488683.

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Vevera, Jan, Alan Hubbard, Arnošt Veselý, and Hana Papežová. "Violent behaviour in schizophrenia." British Journal of Psychiatry 187, no. 5 (2005): 426–30. http://dx.doi.org/10.1192/bjp.187.5.426.

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BackgroundA number of studies have reported increased violence in patients with schizophrenia.AimsTo determine the prevalence of violence among those with schizophrenia in samples from 1949, 1969, 1989 and 2000 in Prague (Czech Republic) and to examine trends in this behaviour.MethodRecords from 404 patients meeting DSM–IV criteria for schizophrenia were screened for violence (defined as 3 points on the Modified Overt Aggression Scale) from the first observed psychotic symptoms until the time of latest available information.ResultsLogistic regression revealed a marginally significant increase
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Bates, P., and J. Rutherford. "Problem substance use and schizophrenia." British Journal of Psychiatry 182, no. 5 (2003): 455. http://dx.doi.org/10.1192/bjp.182.5.455.

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Manseau, Marc, and Michael Bogenschutz. "Substance Use Disorders and Schizophrenia." FOCUS 14, no. 3 (2016): 333–42. http://dx.doi.org/10.1176/appi.focus.20160008.

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Beaudoin, Marie Nathalie, Sheilagh Hodgins, and François Lavoie. "Homicide, Schizophrenia and Substance Abuse or Dependency." Canadian Journal of Psychiatry 38, no. 8 (1993): 541–46. http://dx.doi.org/10.1177/070674379303800803.

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Few studies have extensively studied the aggressive behaviours of mentally disordered offenders. This investigation compared 14 schizophrenics found not guilty of homicide by reason of insanity (NGRI) with 12 schizophrenics convicted of homicide. A comparison group of 15 homicide offenders with no major mental disorder was used. Drug and alcohol consumption, previous history of aggression against others as well as mental health were assessed using standardized, reliable, valid instruments. Significantly more of the inmates with no major mental disorder were diagnosed as having a history of dru
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Bennett, Melanie. "Assessment of Substance Use and Substance-Use Disorders in Schizophrenia." Clinical Schizophrenia & Related Psychoses 3, no. 1 (2009): 50–63. http://dx.doi.org/10.3371/csrp.3.1.5.

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Quigley, Danielle, and Stefania Maggi. "Predicting Substance Use from Childhood Aggression and Prosocial Behaviour." Canadian Journal of Community Mental Health 33, no. 3 (2014): 1–15. http://dx.doi.org/10.7870/cjcmh-2014-011.

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This research uses a longitudinal design to examine aggression and prosocial behaviour as early predictors of substance use behaviours in emerging adulthood. Using data from the National Longitudinal Survey of Children and Youth (NLSCY), self- and maternal reports of early engagement in relationally and physically aggressive behaviours and prosocial behaviours are examined as predictors of cigarette smoking, marijuana use, and alcohol use in emerging adulthood. Using multinomial regression analyses we found that maternal reports of relational aggression significantly predicted daily smoking wh
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Satybaldiyeva, Nora, Erin Delker, and Gretchen Bandoli. "Childhood Aggression and Adolescent Substance Use Initiation." Drug and Alcohol Dependence 260 (July 2024): 110840. http://dx.doi.org/10.1016/j.drugalcdep.2023.110840.

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Steele, Jennifer L., and Robert L. Peralta. "Are Polydrug Users More Physically and Verbally Aggressive? An Assessment of Aggression Among Mono- Versus Polydrug Users in a University Sample." Journal of Interpersonal Violence 35, no. 21-22 (2017): 4444–67. http://dx.doi.org/10.1177/0886260517715024.

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Early research has revealed that patterns of aggression and antisocial behavior are present among polydrug users. Often missing from this discourse is the examination of whether polydrug users are quantitatively different from monodrug users in their use of aggression. Theoretical perspectives are often centered on the psychopharmacological effects of substance use on behavior. Consideration of possible poly- versus monodrug use differences and their impact on aggression has not been investigated. Data from this study were derived from a sample of Midwestern university students ( N = 793). The
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