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Dissertations / Theses on the topic 'Schizophrenia – Risk factors'

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Published: 4 June 2021

Last updated: 12 February 2022

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1

Lee, Heeyoung. "Protective and risk factors in adolescents with schizophrenia /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/7263.

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2

Eriksson, Åsa. "Risk factors for criminal offending among men with schizophrenia." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-666-2/.

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3

Suvisaari, Jaana. "Incidence and risk factors of schizophrenia in Finland." Helsinki : University of Helsinki, 1999. http://ethesis.helsinki.fi/julkaisut/laa/kansa/vk/suvisaari/.

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4

Roberts, Seth. "Season of Birth and Risk for Schizophrenia." VCU Scholars Compass, 2008. http://scholarscompass.vcu.edu/etd/1633.

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Background: Schizophrenia is a chronic, debilitating mental disorder characterized by positive (e.g., hallucinations, delusions) and negative (e.g., catatonia, flat affect) signs and symptoms. Many studies suggest that individuals born in winter or spring months are at increased risk for schizophrenia. Study Objectives: 1) To determine whether season of birth affects risk for schizophrenia in the Irish Study of High Density Schizophrenia Families (ISHDSF). 2) To examine, by computer simulation, power to detect genetic associations with schizophrenia under a variety of conditions and using diff

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5

Spencer, Michelle Kerry. "Examining the use of dynamic risk factors to predict high risk behaviours in people with schizophrenia." Thesis, University of Warwick, 2009. http://wrap.warwick.ac.uk/3261/.

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The following thesis discusses aspects of risk management within a dynamic framework. It focuses on risk management with people with schizophrenia, as they are considered to be at more risk than the general population both of harming others and harming themselves. The literature review summarises current research into suicide risk factors in the schizophrenia population. People with a diagnosis other than schizophrenia, such as schizoaffective disorder, are not included in the review. Studies that are dealing with factors that are open to change (dynamic), or that indicate or trigger imminent

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6

Morgan, Vera Anne. "Intellectual disability co-occurring with schizophrenia and other psychiatric illness : epidemiology, risk factors and outcome." University of Western Australia. School of Psychiatry and Clinical Neurosciences, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0209.

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(Truncated abstract) The aims of this thesis are: (i) To estimate the prevalence of psychiatric illness among persons with intellectual disability and, conversely, the prevalence of intellectual disability among persons with a psychiatric illness; (ii) To describe the disability and service utilisation profile of persons with conjoint disorder; (iii) To examine, in particular, intellectual disability co-occurring with schizophrenia; and (iv) To explore the role of hereditary and environmental (specifically obstetric) risk factors in the aetiology of (i) intellectual disability and (ii) intelle

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7

Pukall, Monica G. "Postnatal risk factors in the etiology of schizophrenia : association with good premorbid adjustment." Thesis, McGill University, 1999. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=30728.

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Research shows distinct premorbid subtypes in schizophrenia. While family history of schizophrenia and obstetric complications are associated with poor premorbid adjustment, risk factors associated with good premorbid adjustment, characterizing most patients, remain unidentified. Both childhood trauma and premorbid substance use appear to increase vulnerability to schizophrenia. The goals of this study were to determine the association among family history, obstetric complications, childhood trauma, and premorbid substance use; and secondly, to assess whether trauma and premorbid substance use

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8

Davie, Brenda J. "Suicidality among individuals with schizophrenia, the interaction of personality and known risk factors." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ30938.pdf.

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9

Pukall, Monica G. "Postnatal risk factors in the etiology of schizophrenia, association with good premorbid adjustment." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ64433.pdf.

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10

Thompson, Rhiannon. "Genetic and functional investigation of FXYD6 and MAP2K7 as risk factors in schizophrenia." Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/4157/.

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Schizophrenia is a debilitating psychiatric disorder with a prevalence of around 1% worldwide. It is an extraordinarily complex syndrome, which encompasses multiple psychological domains leading to the impairment of a range of symptoms. These symptoms are categorised as positive symptoms, negative symptoms and cognitive deficits. The profile of cognitive deficits is broad and severe, and is likely to be present in most, if not all patients. Despite cognitive enhancement being recognised as an important treatment target in schizophrenia, the discovery of an effective treatment has been met with

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11

Hubbard, Leon. "Common and rare genetic risk factors for schizophrenia and their associations with cognition." Thesis, Cardiff University, 2014. http://orca.cf.ac.uk/73174/.

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Individuals with schizophrenia have severe cognitive impairments that impact upon their ability to function within society. Better understanding the genetic mechanisms underlying schizophrenia and cognition provides an opportunity for targeted pharmacological intervention. This thesis investigates common and rare genetic variation in schizophrenia and their associations with cognitive ability in schizophrenia cases and healthy controls. Polygenic risk of schizophrenia and bipolar disorder predicted ability on tests of cognitive domains affected in schizophrenia, performance, verbal and full sc

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12

Filatova, S. (Svetlana). "Incidence of schizophrenia and associations of schizophrenia and schizotypy with early motor developmental milestones." Doctoral thesis, Oulun yliopisto, 2017. http://urn.fi/urn:isbn:9789526217178.

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Abstract Schizophrenia is a complex mental health disorder and its etiology can be investigated based on different theoretical prerequisites. The present thesis examines schizophrenia from the neurodevelopmental and psychosis continuum perspectives. Neurodevelopmental theories of schizophrenia see abnormalities in the developing nervous system as early predictors of vulnerability to the disease. Schizophrenia can be seen also as a progressive disorder and a continuum of symptomatology from personality traits (schizotypy) to full-blown schizophrenia. The aim of the present thesis is to study in

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13

Keskinen, E. (Emmi). "Parental psychosis, risk factors and protective factors for schizophrenia and other psychosis:the Northern Finland Birth Cohort 1966." Doctoral thesis, Oulun yliopisto, 2015. http://urn.fi/urn:isbn:9789526210483.

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Abstract The aim of this study was to investigate whether risk factors for psychosis are different among those with and without parental psychosis, and to study the interaction between parental psychosis and risk factors. Protective factors for psychosis were also examined. Data from the Northern Finland Birth Cohort 1966 (N = 10,458) was used. Biological risk factors in particular increased the risk for schizophrenia and other psychosis among those with parental psychosis. In the same group, the risk for schizophrenia was increased if the achievement of holding the head up and touch

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14

Zammit, Stanley. "An investigation into the use of cannabis and tobacco as risk factors for schizophrenia." Thesis, Cardiff University, 2004. http://orca.cf.ac.uk/48919/.

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15

Masse, Marjolaine. "Risk factors for premorbid cannabis use and the relationship between cannabis use and schizophrenia symptoms." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=95187.

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Cannabis use increases the risk for psychosis with a dose response relationship; the risk is particularly strong before age 15. Factors precipitating use and explaining total amount used in patients are unknown. It is likewise unknown whether patients and controls differ on predictor profiles. The amount of variance in psychotic symptoms explained by premorbid cannabis use and the unique contribution of cannabis use when controlling for risk factors for schizophrenia is also unknown. The results show that some risk factors found in the community apply to both groups in the same way, and oth

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16

Stålberg, Gabriella. "Vulnerability and Social Functioning in Schizophrenia." Doctoral thesis, Uppsala universitet, Psykiatri, Akademiska sjukhuset, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-209626.

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This thesis offers a broad approach in elucidating biological risk factors, as well as psychological and social functioning in schizophrenia. The aims are as follows: (I) investigate the association between birth characteristics and schizophrenia, (II) study the association between levels of neurotransmitter neuropeptide Y (NPY) in cerebrospinal fluid (CSF), social function and longitudinal outcome in schizophrenia, (III) compare social functioning of patients with schizophrenia with their biological siblings and (IV) explore how siblings to patients with schizophrenia perceive the sibling rel

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17

Nilsson, Emma. "Genetic epidemiological studies of adverse pregnancy outcomes and the role of schizophrenia /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-590-9/.

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18

Stokes, Paul Robert Alexander. "Investigating the effects of gnetic and environmental risk factors for schizophrenia on the human dopaminergic system." Thesis, Imperial College London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.530447.

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19

Dickson, Marguerite Mulryan. "Genetic and psychiatric treatment related risk factors for type 2 diabetes in schizophrenia and schizoaffective disorder patients." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2009r/dickson.pdf.

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20

Alaräisänen, A. (Antti). "Risk factors and pathways leading to suicide with special focus in schizophrenia:the Northern Finland 1966 Birth Cohort Study." Doctoral thesis, University of Oulu, 2010. http://urn.fi/urn:isbn:9789514262630.

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Abstract The aim of this study was to investigate risk factors, developmental pathways and the rate of attempted or accomplished suicide in a longitudinal population-based prospective birth cohort. The Northern Finland 1966 Birth Cohort (NFBC 1966) consists of 12,068 pregnant women with expected dates of delivery in 1966, and their 12,058 live-born children. The data used here was collected prospectively for 10,934 individuals who were alive and resident in Finland at the age of 16. This study utilized an extensive data set collected in antenatal clinics at mid-pregnancy, by postal questionnai

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21

Stenson, Gillian. "Impact of environmental risk factors for schizophrenia on the developing brain : characterisation of the effects of polyIC and THC on functional neural systems and behaviour." Thesis, University of Strathclyde, 2012. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=19517.

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Cannabis abuse can produce deficits in cognition and has been implicated as a 'late' environmental risk factor in the pathogenesis of the poly-factorial disorder schizophrenia. Evidence suggests an age-related susceptibility to the deleterious effects of cannabis as early onset of use may increase the vulnerability of the brain to the adverse consequences of cannabis abuse. Animal models are crucial for exploration of mechanistic and causative theories, and long-term behavioural consequences of adolescent cannabis abuse in a controlled experimental environment. This thesis evaluates the vulner

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22

Mungly, Shazia. "The Prevalence Of Metabolic Disorders And Their Associated Risk Factors In Forensic Patients With Schizophrenia Spectrum Disorders On Clozapine Compared To Haloperidol At Valkenberg Hospital." Master's thesis, Faculty of Health Sciences, 2019. http://hdl.handle.net/11427/31076.

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Background: Various studies have shown that people with serious mental illness have an increased risk for metabolic syndrome with prevalence ranging from 28.7% to 60%. Given the amount of evidence suggesting a link between clozapine and metabolic syndrome, several guidelines have recommended regular clinical monitoring of metabolic syndrome in patients on clozapine. Aim: To determine the screening, prevalence and associated risk factors of metabolic disorders in forensic patients with schizophrenia spectrum disorders who are on clozapine (study group) compared to patients on haloperidol (contr

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23

Prats, Balado Claudia. "Genetic risk factors in Schizophrenia and Neurodevelopmental disorders: Association and epistatic analyses of Neuritin-1 gene and white matter related genes = Factores genéticos en esquizofrenia y enfermedades del neurodesarrollo: análisis de asociación y epistáticos en el gen Neuritina-1 y en genes relacionados con la materia blanca." Doctoral thesis, Universitat de Barcelona, 2017. http://hdl.handle.net/10803/456897.

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Nowadays, it is estimated that about 450 million people suffer from a mental or behavioural disorder in the world. According to World health organization (WHO), 33% of the years lived with disability (YLD) are due to psychiatric disorders. In this regard, psychotic disorders including schizophrenia (SZ), remain one of the most mysterious and costliest mental disorders in terms of human suffering and social expenditure. In recent years, the field of molecular genetics has been uncovering evidence of the complex polygenetic architecture of SZ and related disorders. In addition, GWAS studies ha

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24

Mitjans, Niubó Marina. "Genetic Risk Factors for the Lack of Response to Clinical Treatment in Mental Disorders: an Approach from Pharmacogenetics." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/289981.

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Severe mental disorders, such as Major Depressive Disorder (MDD), Bipolar Disorder (BD) and Schizophrenia (SCZ), represent a huge burden to society, reflecting the limited efficacy of current drug treatments. Although the progress in development of pharmacological treatments is one of the great successes of modern psychiatry, it should not be forgotten that a very high percentage of patients do not receive and/or seek the proper treatment for their disease. Individual differences in clinical response to psychotropic drugs have long been recognized as a fundamental problem in the treatment of t

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25

Rothärmel, Maud. "La résistance pharmacologique dans les pathologies psychiatriques : Exemple de la dépression, la schizophrénie et l'autisme. Identification of potential genetic risk factors for bipolar disorder by whole-exome sequencing Les traitements pharmacologiques dans les troubles du spectre de l’autisme Troubles de l’humeur ? Quand recourir à la stimulation magnétique transcrânienne ? Repeated transcranial magnetic stimulation (rTMS) to improve electroconvulsive therapy (ECT) in TReatment-Resistant Depression : a report of two cases." Thesis, Normandie, 2019. http://www.theses.fr/2019NORMR125.

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Le problème de la pharmacorésistance est un phénomène courant en médecine et qui n’épargne pas la psychiatrie. Au même titre qu’on parle « d’épilepsie résistante », on parle de « dépression ou de schizophrénie résistante ». L’autisme est une situation un peu différente dans la mesure où il n’existe pas de traitement de référence pour les troubles du neurodéveloppement. Ces trois troubles, néanmoins, constituent des enjeux majeurs de santé publique tant du point de vue économique que sociétal, avec d’importantes répercussions fonctionnelles pour les patients. Après nous être interrogés dans une

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26

Roisko, R. (Riikka). "Parental Communication Deviance as a risk factor for thought disorders and schizophrenia spectrum disorders in offspring:The Finnish Adoptive Family Study." Doctoral thesis, Oulun yliopisto, 2014. http://urn.fi/urn:isbn:9789526206066.

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Abstract Both genetic and biological and psychosocial environmental risk factors contribute to the aetiology of schizophrenia spectrum disorders. Among the much studied environmental risk indicators are parental Communication Deviance (CD) and the winter or spring birth of a child. Genetic and environmental risk factors do not function in isolation from each other, but gene-environment interactions play a major role in the aetiology of psychotic disorders. The aim of this doctoral thesis is to investigate the role of parental CD as a risk factor (together with other risk indicators) for though

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27

Badowska, Dorota [Verfasser], Moritz [Akademischer Betreuer] Rossner, Hannelore [Akademischer Betreuer] Ehrenreich, André [Akademischer Betreuer] Fischer, Michael [Akademischer Betreuer] Hoerner, and Mikael [Akademischer Betreuer] Simons. "Schizophrenia risk factor Tcf4 and gene-environment interaction in mice / Dorota Badowska. Gutachter: Hannelore Ehrenreich ; André Fischer ; Michael Hoerner ; Mikael Simons. Betreuer: Moritz Rossner." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2015. http://d-nb.info/1067626573/34.

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28

Burt, Melissa. "Investigating the effect of prenatal immune activation, a risk factor for Schizophrenia, on hippocampal n-methyl-d- aspartate receptor function in a rodent model." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119491.

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N-methyl-D-aspartate receptor (NMDAR) hypofunction has been hypothesized as a pathological change accounting for many of the symptoms of schizophrenia, including cognitive deficits. Although the etiology of schizophrenia is still not known, prenatal infection has been identified as an early-life environmental risk factor. While the onset of psychosis commonly occurs in early adulthood, cognitive deficits can be present earlier. Exposure to risk factors during adolescence, such as stress, is hypothesized to precipitate the onset of psychosis. Recent findings suggest stress may impact cognition

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29

Chaumette, Boris. "Identification de facteurs biologiques de la transition psychotique." Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCB046/document.

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La psychose est un syndrome apparaissant progressivement à l’adolescence chez des individus à risque selon un processus dynamique appelé transition psychotique. Ces individus à risque sont repérables cliniquement mais les données biologiques actuelles sont insuffisantes pour expliquer l’apparition de la psychose. Au cours de cette thèse, nous avons cherché à identifier les facteurs biologiques responsables de ce processus. Les hypothèses permettant d’expliquer la transition psychotique privilégient l’interaction gène x environnement, sous-tendue par des mécanismes épigénétiques. Nous avons men

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Yerabham, Antony Sravan Kumar [Verfasser], Carsten [Gutachter] Korth, and Georg [Gutachter] Groth. "Investigations of the structural organization of the Disrupted-in-Schizophrenia 1 (DISC1) protein, a major risk factor for mental illness / Antony Sravan Kumar Yerabham ; Gutachter: Carsten Korth, Georg Groth." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2017. http://d-nb.info/1138114480/34.

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31

Tang, Chao-Jung, and 湯昭容. "The Related Factors of High Risk Behavior for Patient with Schizophrenia." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/64978899018658917707.

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碩士<br>國立臺灣大學<br>護理學研究所<br>90<br>ABSTRACT The purpose of this study was to explore the related factors of high-risk sexual behaviors of patients with schizophrenia. A descriptive correlation study design was used. Structured questionnaires were filled by the investigator through interviews. A purposive sample of 208 patients of schizophrenia came from outpatient psychiatric departments of a medical center and a psychiatric hospital in central Taiwan. Descriptive and inferential statistics were used for data analysis. Major findings of this study included: 1. Pat

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KUO, HUI-WEN, and 郭惠雯. "A Study of Schizophrenia Risk Factors for Rehospitalization in One Year." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/78221492500538148557.

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碩士<br>國立臺北護理健康大學<br>健康事業管理研究所<br>101<br>Background: The prevalence rate of psychiatric disorders was 53‰ in Taiwan. Both in the acute psychiatric ward or chronic psychiatric ward, most patients were schizophrenia. In acute psychiatric ward, 58% patients were schizophrenia. In chronic psychiatric ward, 80% patients were schizophrenia. Schizophrenia was a chronic and lifelong mental illness. As patients with schizophrenia often relapse, it consumed a lot of social and medical resources. Objectives: The purpose of this study was to investigate the risk factors affecting the rehospitalization in p

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Cheng, Chin-Chi, and 鄭沁綺. "The Survey of the Risk Factors for Metabolic Syndrome in Schizophrenia." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/12422917004010335251.

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碩士<br>高雄醫學大學<br>行為科學研究所碩士班<br>95<br>Objective: The metabolic syndrome has been recognized as a side effect of antipsychotic treatment. ApoE polymorphism was associated with lipid metabolism in the metabolic syndrome. The study explored the relationship of schizophrenia and metabolic syndrome and predicted the prevalence about the risk of metabolic syndrome in the atypical antipsychotic treatment. Further, we explored the relationship between the ApoE genotypes and metabolic syndrome in schizophrenic patients. Method: This is a retrospective and chart review study. Total of 111 Taiwanese patien

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Cheng, Liang-Chih, and 鄭良志. "An Investigation of the Risk Factors for Prediction Pneumonia among Schizophrenia Inpatients." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/9kx6u9.

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碩士<br>義守大學<br>醫務管理學系<br>106<br>Backgroubd and purpose: Schizophrenia regards as severe mental disorder diseases. Ever increaing patients are treated with medications mainly, though 2nd generation antipsychotic Clozapine has less extrapyramidal symptoms still left serious adverse effect, including pneumonia. This thesis focus on study of Clozapine Induced Pneumonia and other risk factors. Materials and Methods: This thesis investigate on how Schizophrenia patients after taking Clozapine and other factors might lead to pneumonia. The research main focus includes variable factors of population, m

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Tseng, Chiu-Yu, and 曾秋玉. "Exploration of Risk Factors of Glycemic Control in Patients with Schizophrenia and Diabetes." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/63382940854827245168.

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碩士<br>高雄醫學大學<br>藥學系碩士在職專班<br>105<br>Background: In recent years, many studies have found that sleep quality and glycemic control are highly correlated, but few studies have extensively investigated the relations of glycemic control, sleep quality and drugs. Especially in many patients with schizophrenia are not only using a single anti- psychotropic drugs but also using mood stabilizers. Objective: This study was aimed to investigate the relations of glycemic control efficacy, quality of sleep, drugs and physiological diseases in hospitalized patients with schizophrenia and Diabetes. Also ana

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Liang, Yu-Min, and 梁鈺敏. "Risk Factors Associated with the Relapse of Schizophrenia－Application of the Survival analysis of Cox ProportionalHazards Model." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/11714947329028966912.

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碩士<br>高雄醫學大學<br>行為科學研究所碩士班<br>94<br>Objective：The aim of this study was to use the method of the survival analysis of cox proportional hazards models to explore the risk factors of relapse in schizophrenia, according to several articles about this issues , the risk factors associated with the relapse in schizophrenia were investigated from the anamnesis. Methods：Cases consisted of 94 patients who were diagnosed as schizophrenia （295.0-295.9）by psychiatrists from one of the teaching hospital in southern Taiwan. All of these patients were required to have the condition of first hospitalization a

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Cheng-Chen and 張正辰. "Variability of waist circumference measurements at three sites and its relationship with cardiovascular risk factors in patients with schizophrenia." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/11267723539853484015.

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碩士<br>中山醫學大學<br>醫學研究所<br>98<br>Objective：1. To compare the magnitude of waist circumference (WC) measured at 3 sites (immediately above the iliac crest, midpoint between the lowest rib and the iliac crest, umbilical level) in males and females. 2. To examine the correlation of WC with lipid profiles, glucose and metabolic syndrome. Methods and Materials： Patients with the DSM-IV diagnosis of schizophrenia, regular follow-up at an outpatient clinic were recruited. After explaining the purpose of the study and obtaining patient’s agreement, the following data are collected: age, gender, educati

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Shumar, Erik. "Associations between Homelessness and Psychiatric Symptom Severity and How Homelessness Interacts with Risk Factors among First-Admission Psychiatric Patients." Thesis, 2014. https://doi.org/10.7916/D8FJ2DZV.

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Individuals who experience homelessness are exposed to stressors that have the potential to precipitate mental and physical health complications that can present serious threats to multiple areas of these individuals' lives. Although the path to becoming and remaining homeless is different for every individual, there may be some commonality specific to homelessness that makes certain individuals who experience homelessness more vulnerable than other individuals to the expression and potentially devastating course of psychopathology. Guided by the diathesis-stress model, the intent of this st

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Motta, Carolina Dall'Antónia da. "Uncovering the endophenotypic factors on the impact of functional outcomes in schizophrenia: studies on different genetic risk samples from the Portuguese Population." Doctoral thesis, 2020. http://hdl.handle.net/10316/92414.

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Tese no âmbito do Doutoramento em Psicologia, especialidade em Psicologia Clínica apresentada à Faculdade de Psicologia e Ciências de Educação da Universidade de Coimbra.<br>The administration of neurophysiological, neurocognitive and behavioral measures as endophenotypes in studies about schizophrenia is in vogue, particularly the inquiry on their interrelationships and their impact on patient’s functional outcome. To this date, increasingly large Portuguese samples with genetic risk to schizophrenia (patients and families) have been integrated into studies about candidate genes to schizoph

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"Environmental Stimuli Activates Early Growth Response 3 (EGR3), an Immediate Early Gene Residing at the Center of a Biological Pathway Associated with Risk for Schizophrenia." Doctoral diss., 2020. http://hdl.handle.net/2286/R.I.63032.

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abstract: Schizophrenia, a debilitating neuropsychiatric disorder, affects 1% of the population. This multifaceted disorder is comprised of positive (hallucinations/psychosis), negative (social withdrawal/anhedonia) and cognitive symptoms. While treatments for schizophrenia have advanced over the past few years, high economic burdens are still conferred to society, totaling more than $34 billion in direct annual costs to the United States of America. Thus, a critical need exists to identify the factors that contribute towards the etiology of schizophrenia. This research aimed to determine the

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Σταθοπούλου, Αναστασία. "Ενδομήτρια έκθεση στον καπνό του τσιγάρου, κίνδυνος εκδήλωσης σχιζοφρένειας και βαρύτητα θετικών/αρνητικών αποτελεσμάτων". Thesis, 2014. http://hdl.handle.net/10889/7994.

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Η προγεννητική έκθεση στον καπνό του τσιγάρου προκαλεί χρόνια εμβρυϊκή υποξία, απορρύθμιση της ομαλής λειτρουγίας του ενδοκρινικού συστήματος, και διαταραχή της νευροανάπτυξης του εμβρύου, η οποία σχετίζεται με εγκεφαλική δυσλειτουργία, τα οποία δυνητικά θα μπορούσαν να προκαλέσουν ευαλωτότητα για σχιζοφρένεια.. Συνολικά 212 ασθενείς με σχιζοφρένεια ηλικίας 14-30 ετών, και 212 αντίστοιχοι μάρτυρες μελετήθηκαν. Η προγεννητική έκθεση στον καπνό του τσιγάρου των ασθενών με σχιζοφρένεια συγκρίθηκε με εκείνη των μαρτύρων εφαρμόζοντας ανάλυση λογιστικής παλινδρόμησης και έλεγχο για διάφορους παράγ

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Auerbach, Isabelle. "Kindliche Traumatisierung, elterliche Erziehungsstile, familiäre Vorbelastung und Geburtsrisikofaktoren bei Patienten mit Schizophrenie." Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-0006-B2F6-0.

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Shing-Chia, Chen. "Heterogeneity and Risk factors of Aggressive Acts among Schizophrenic Inpatients." 2005. http://www.cetd.com.tw/ec/thesisdetail.aspx?etdun=U0001-0108200519064200.

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Chen, Shing-Chia, and 陳杏佳. "Heterogeneity and Risk factors of Aggressive Acts among Schizophrenic Inpatients." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/38296465019485419625.

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博士<br>國立臺灣大學<br>護理學研究所<br>93<br>Background: Psychiatric inpatients’ aggressive acts can occur frequently and are recognized as a significant problem in psychiatric settings. Understanding of aggressive acts in clinical settings is still incomplete and the clinical care of aggressive acts remains unsatisfactory. It is therefore crucial to establish objective measures and to develop insights into the heterogeneity and related risk factors of aggressive acts, for improvement in the management and prevention of aggressive acts. Objective: The purpose of this study has a many-fold intention depicte

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Badowska, Dorota. "Schizophrenia risk factor Tcf4 and gene-environment interaction in mice." Doctoral thesis, 2014. http://hdl.handle.net/11858/00-1735-0000-0022-5DCD-B.

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Tseng, Pei-Hsin, and 曾姵馨. "Risk and determined factars of developing Dementia in patients with Schizophrenia." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/90548900711352052784.

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碩士<br>中山醫學大學<br>醫療產業科技管理學系碩士班<br>103<br>Background:As the global population aging, advances in medical technology, the elderly population is growing ensue a rapid increase in dementia and schizophrenia patients. World Health Organization in April 2012 report released by the Global dementia, estimated in 2010 of 35.6 million worldwide with dementia, with 7.7 million annual increase rate of growth, that is, about every four seconds on a new diseased person. According to the study,schizophrenia patients may got hypertension, diabetes,cerebrovascular disease , metabolic syndrome related comorbidit

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Dragomir, Elena Alice. "Évaluation de l'impact clinique et économique du développement d'un traitement pour la schizophrénie." Thèse, 2010. http://hdl.handle.net/1866/4818.

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Contexte : Les stratégies pharmacologiques pour traiter la schizophrénie reçoivent une attention croissante due au développement de nouvelles pharmacothérapies plus efficaces, mieux tolérées mais plus coûteuses. La schizophrénie est une maladie chronique présentant différents états spécifiques et définis par leur sévérité. Objectifs : Ce programme de recherche vise à: 1) Évaluer les facteurs associés au risque d'être dans un état spécifique de la schizophrénie, afin de construire les fonctions de risque de la modélisation du cours naturel de la schizophrénie; 2) Développer et valider un modèl

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Lin, Chia-Jung, and 林嘉容. "Explore the Moderation and Mediation Effects among those Risk Factors of the Treatment of Schizophrenia:A Longitudinal Study." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/57607287032319739600.

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碩士<br>淡江大學<br>數學學系碩士班<br>98<br>Schizophrenia is a complex and heterogeneous psychosis. The durations of antipsychotic trial for drug treatment of schizophrenia recommend to at least 42 days. Efficacy and drug safety were assessed on days 0, 14, 28, and 42. Therefore, the data structure is a longitudinal dependent data. We have published 20 papers to explore the relationship between the treatment effects of schizophrenia and some potential prognostic/risk factors. Those factors can be classified into three major areas: genes, disease related factors and patients’ personal characteristics. Effic

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Mei-Kuei and 吳梅桂. "The risk factors of cardiovascular disease and the effect of diet and physical activity program in clozapine-treated schizophrenic obesity." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/81974959043939493828.

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博士<br>中山醫學大學<br>營養學研究所<br>96<br>Schizophrenia has a prevalence of 1 percent in all cultures and is equally common in men and women. It is a devastating mental illness that impairs mental and social functioning. Clozapine is effective in treating not only the positive symptoms of schizophrenia, but also in reducing negative symptoms and cognitive deficits. Several studies have reported significant weight gain with clozapine and the largest weight gains seen with antipsychotic drug and had a significantly higher mean BMI value and rate of obesity than patients treated with other SGAs. Obese pati

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Chen, Po-Yu, and 陳柏妤. "Family history of obesity related metabolic diseases as the risk factor of metabolic disturbances in schizophrenic patients receiving antipsychotics." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/61122088915656095016.

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碩士<br>國立臺灣大學<br>臨床醫學研究所<br>96<br>Objective: Obesity and diabetes mellitus are common side effects during antipsychotics treatment. These side effects may predispose cardiovascular diseases and decrease antipsychotics compliance in schizophrenic patients. Higher prevalence of metabolic diseases in schizophrenic patients was frequently reported in many countries. However, there are not many studies of the prevalence of metabolic diseases in community patients in Taiwan. Different effects on metabolic disease among various antipsychotics have been broadly discussed. However, clinical risk factors

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