Academic literature on the topic 'Secretion stress'

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Journal articles on the topic "Secretion stress"

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Seo, Jin, Anja Brencic, and Andrew J. Darwin. "Analysis of Secretin-Induced Stress in Pseudomonas aeruginosa Suggests Prevention Rather than Response and Identifies a Novel Protein Involved in Secretin Function." Journal of Bacteriology 191, no. 3 (2008): 898–908. http://dx.doi.org/10.1128/jb.01443-08.

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ABSTRACT Secretins are bacterial outer membrane proteins that are important for protein export. However, they can also mislocalize and cause stress to the bacterial cell, which is dealt with by the well-conserved phage shock protein (Psp) system in a highly specific manner. Nevertheless, some bacteria have secretins but no Psp system. A notable example is Pseudomonas aeruginosa, a prolific protein secretor with the potential to produce seven different secretins. We were interested in investigating how P. aeruginosa might deal with the potential for secretin-induced stress without a Psp system.
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Delbende, C., C. Delarue, H. Lefebvre, et al. "Glucocorticoids, Transmitters and Stress." British Journal of Psychiatry 160, S15 (1992): 24–35. http://dx.doi.org/10.1192/s0007125000296657.

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Many kinds of stress stimulate the neuroendocrine systems controlling catecholamine and glucocorticoid secretion. Stress-induced stimulation of CRF-containing neurons appears to be mediated by serotonergic, noradrenergic, and possibly other neuronal pathways. Stress can alter various neurobiological and endocrine functions, two essential components of the neuroendocrine responses being release of adrenalin from chromaffin cells of the adrenal medulla and secretion of glucocorticoids from adrenocortical cells. Activation of adrenal steroid secretion is mainly by a reflex activation of hypothala
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Cramer, Robert A. "Secretion stress and fungal pathogenesis." Virulence 2, no. 1 (2011): 1–3. http://dx.doi.org/10.4161/viru.2.1.13902.

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Aguiar, Tatiana Q., Orquídea Ribeiro, Mikko Arvas, Marilyn G. Wiebe, Merja Penttilä, and Lucília Domingues. "Investigation of protein secretion and secretion stress in Ashbya gossypii." BMC Genomics 15, no. 1 (2014): 1137. http://dx.doi.org/10.1186/1471-2164-15-1137.

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Zhang, Irina X., Jianhua Ren, Suryakiran Vadrevu, Malini Raghavan, and Leslie S. Satin. "ER stress increases store-operated Ca2+ entry (SOCE) and augments basal insulin secretion in pancreatic beta cells." Journal of Biological Chemistry 295, no. 17 (2020): 5685–700. http://dx.doi.org/10.1074/jbc.ra120.012721.

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Type 2 diabetes mellitus (T2DM) is characterized by impaired glucose-stimulated insulin secretion and increased peripheral insulin resistance. Unremitting endoplasmic reticulum (ER) stress can lead to beta-cell apoptosis and has been linked to type 2 diabetes. Although many studies have attempted to link ER stress and T2DM, the specific effects of ER stress on beta-cell function remain incompletely understood. To determine the interrelationship between ER stress and beta-cell function, here we treated insulin-secreting INS-1(832/13) cells or isolated mouse islets with the ER stress–inducer tun
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Freeman, H., K. Shimomura, R. D. Cox, and F. M. Ashcroft. "Nicotinamide nucleotide transhydrogenase: a link between insulin secretion, glucose metabolism and oxidative stress." Biochemical Society Transactions 34, no. 5 (2006): 806–10. http://dx.doi.org/10.1042/bst0340806.

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This paper reviews recent studies on the role of Nnt (nicotinamide nucleotide transhydrogenase) in insulin secretion and detoxification of ROS (reactive oxygen species). Glucose-stimulated insulin release from pancreatic β-cells is mediated by increased metabolism. This elevates intracellular [ATP], thereby closing KATP channels (ATP-sensitive potassium channels) and producing membrane depolarization, activation of voltage-gated Ca2+ channels, Ca2+ influx and, consequently, insulin secretion. The C57BL/6J mouse displays glucose intolerance and reduced insulin secretion, which results from a na
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Žarković, Miloš, Elka Stefanova, Jasmina Ćirić, et al. "Prolonged psychological stress suppresses cortisol secretion." Clinical Endocrinology 59, no. 6 (2003): 811–16. http://dx.doi.org/10.1046/j.1365-2265.2003.01925.x.

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Holtmann, Gerald, Reinholde Kriebel, and Manfred V. Singer. "Mental stress and gastric acid secretion." Digestive Diseases and Sciences 35, no. 8 (1990): 998–1007. http://dx.doi.org/10.1007/bf01537249.

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Giuliani, Fabrizio, Adam Grieve, and Catherine Rabouille. "Unconventional secretion: a stress on GRASP." Current Opinion in Cell Biology 23, no. 4 (2011): 498–504. http://dx.doi.org/10.1016/j.ceb.2011.04.005.

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Belay, Tesfaye, Alexis Ray, and Kaitlyn Cook. "Cytokine production profiles of immune cells of stressed beta2-adrenergic receptor knockout mouse model during Chlamydia muridarumgenital infection." Journal of Immunology 210, no. 1_Supplement (2023): 81.10. http://dx.doi.org/10.4049/jimmunol.210.supp.81.10.

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Abstract Chlamydia genital infection by Chlamydia trachomatisis the most common bacterial sexually transmitted disease worldwide. The relationships between stress and chlamydia genital infection remain unknown. Beta2-adrenergic receptor(β2-AR), the major receptor of the stress hormone norepinephrine (NE), is known to impair the function of immune cells. Stress was induced by immersing mice in cold water for five minutes daily for 21 days before infection. This study determined profiles of immune cells of stressed β2-AR KO and stressed WT C57BL/6J after 48 h of Chlamydia muridarumgenital infect
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Dissertations / Theses on the topic "Secretion stress"

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Smart, Darren. "Stressors & LH secretion in the ewe." Thesis, University of Liverpool, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333607.

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Parker, Victoria Joanne. "Hypothalamic mechanisms mediating inhibition of prolactin secretion following stress in early pregnant mice." Thesis, University of Edinburgh, 2012. http://hdl.handle.net/1842/6485.

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In early pregnancy prolonged exposure to stress is known to have profound adverse effects on reproduction and is associated with suppressed progesterone secretion and consequent disturbance of the pregnancy-protective cytokine milieu, thus threatening early pregnancy maintenance. Maternal neuroendocrine responses to stress in early pregnancy are poorly understood. Therefore, we designed experiments to (1) study the hypothalamo-pituitary-adrenal (HPA) axis responses to stress in early pregnant mice, to discover whether and how responses change and (2) to determine the effect of stress in early
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Kim, Beob Gyun. "INFLUENCES OF CHROMIUM (III) PICOLINATE ON PIGS UNDER THERMAL, IMMUNE OR DIETARY STRESS, AND ON ADRENAL STEROID SECRETION." UKnowledge, 2007. http://uknowledge.uky.edu/gradschool_diss/560.

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The objectives were to investigate the effects of chromium (III) picolinate (CrPic; up to 2,000 ppb of Cr) on growing pigs subjected to a variety of stressors including thermal, immune, or dietary stress and to examine the effects of CrPic on steroidogenesis from adrenocortical cells. In the thermal stress study, high ambient temperature caused reduced weight gain and feed consumption (P andlt; 0.01), and low ambient temperature caused increased feed intake and feed:gain (P andlt; 0.01). However, these effects were not moderated by CrPic, and respiratory rate, plasma cortisol, or plasma glucos
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Kosti, Ourania. "Intra-adrenal mechanisms in the control of steroid secretion and the response to stress." Thesis, Queen Mary, University of London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.411344.

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Weber, Barbara. "Stress response and virulence in Vibrio anguillarum." Doctoral thesis, Umeå : Institutionen för molekylärbiologi (Teknisk-naturvetenskaplig fakultet), Umeå universitet, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-33269.

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Marin, Marie-France. "Immediate and delayed effects of stress on a reactivitated declarative long-term memory trace." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116034.

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In 1968, a study demonstrated that consolidated memories can be affected again if they are reactivated. Given the importance of the stress hormones glucocorticoids (GCs) on memory consolidation, the goal of the current study was to assess whether GCs had the capacity to affect a reactivated long-term memory and whether neutral and emotional memories were affected differently. At the first session, participants encoded a movie containing neutral and emotional scenes. Two days later, they recalled the story. Half of them were then exposed to a psychosocial stressor. Memory performance was assess
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Pilgrim, Kamala. "Mechanisms underlying cortisol reactivity to stress in low and high socioeconomic status individuals : role of naturally-occurring attentional biases." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116040.

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This Master's dissertation explored whether a rapid orienting of attention toward or away from social stress information during a restful state, relates to the magnitude of glucocorticoids (GC) released in response to a stressor, the Trier Social Stress Test (TSST). It also assessed whether childhood rearing in a low socioeconomic status (SES) context mediates this relationship. Subjects rested for 45 minutes during which time they completed a modified version of Posner's attention paradigm, comprising social stress words. Immediately following, participants were exposed to the stressor. Resul
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Valiquette, Luc François. "Association between self-reported childhood maltreatment and cortisol profiles in psychotic patients." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112314.

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Childhood maltreatment is extremely common in patients diagnosed with psychotic disorders. Moreover, it has been linked with impaired functioning of the Hypothalamic-Pituitary-Adrenal axis. Furthermore, abnormality of the HPA has been found in psychotic patients. Presence of childhood maltreatment could then explain why the HPA axis is dysfunctional in these subjects. Our objective was to clarify the role of childhood trauma in the cortisol profiles of psychotic patients. Thirty-one patients underwent assessments of childhood maltreatment. Diurnal cortisol and cortisol after a controlled psych
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Alharake, Jawad. "Study of genetic factors involved in enzyme secretion in hyperproductive strains of Trichoderma reesei." Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPASB061.

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Les combustibles fossiles sont un contributeur majeur au réchauffement climatique, et leur nature non renouvelable est un obstacle à la construction de sociétés durables. Dans ce contexte, les biocarburants de seconde génération se présentent comme une alternative attractive et plus respectueuse de l'environnement. Le processus de production de biocarburants de deuxième génération comprend plusieurs étapes incluant le prétraitement physico-chimique de la biomasse lignocellulosique (non comestible), l'hydrolyse enzymatique de la cellulose en glucose et par la fermentation de sucres simples en b
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Solà, Tapias Núria. "The involvement of the three main inflammatory bowel disease pathways and the secretion of trypsin proteolytic activity on intestinal epithelial cells." Thesis, Toulouse 3, 2018. http://www.theses.fr/2018TOU30049/document.

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Les maladies inflammatoires chroniques de l'intestin (MICI) se caractérisent par une inflammation sévère de l'intestin grêle et du côlon et comprennent la maladie de Crohn (MC) et la rectocolite hémorragique (RCH). Les MICI sont des maladies complexes faisant intervenir des facteurs génétiques : certains senseurs bactériens, l'autophagie et le stress du réticulum endoplasmique. Un défaut de barrière de l'épithélium digestif est également fortement impliqué dans la physiopathologie du processus inflammatoire. La fonction barrière de l'épithélium digestif est assurée par plusieurs types cellulai
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Books on the topic "Secretion stress"

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Isasi, José Luis Cano. El secreto del tren eléctrico. CIPUR, 1989.

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1950-, Caballero José Luis, ed. Los secretos de las calles de Barcelona. Ma Non Troppo, 2010.

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Barreto, Mascarenhas. Cristóvão Colombo, agente secreto de el-Rei D. João II. Ediões ASA, 1992.

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Herman, James P. Limbic Pathways to Stress Control. Edited by Israel Liberzon and Kerry J. Ressler. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190215422.003.0008.

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Appropriate control of the HPA (hypothalamo-pituitary-adrenocortical axis) is required for adaptation to physiological and environmental challenges. Inadequate control is linked to numerous stress-related pathologies, including PTSD, highlighting its importance in linking physiological stress responses with behavioral coping strategies. This chapter highlights neurocircuit mechanisms underlying HPA axis adaptation and pathology. Control of the HPA stress response is mediated by the coordinated activity of numerous limbic brain regions, including the prefrontal cortex, hippocampus, and amygdala
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Young, Allan H., and Mario F. Juruena. Hypothalamic–pituitary–adrenal axis. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198789284.003.0006.

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Increased adrenocortical secretion of hormones, primarily cortisol in depression, is one of the most consistent findings in neuropsychiatry. The maintenance of the internal homeostatic state of an individual is facilitated by the ability to circulate glucocorticoids to exert negative feedback on the secretion of hypothalamic–pituitary–adrenal (HPA) hormones through binding to mineralocorticoid and glucocorticoid receptors, thus limiting the vulnerability to diseases related to psychological stress in genetically predisposed individuals. The HPA axis response to stress can be thought of as a cr
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Marini, John J., and Paolo Formenti. Pathophysiology and prevention of sputum retention. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0119.

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Retention of airway mucus is one of the major problem that confronts post-operative and critically-ill patients, as well as the caregivers that address it. Retained secretions increase the work of breathing and promote hypoxaemia, atelectasis, and pneumonia. The airway-intubated patient is at particular risk of retaining mucus, as the presence of the tube interrupts normal flow of airway secretions toward the larynx by the mucociliary escalator and coughing effectiveness is degraded by a glottis that is stented open and cannot close effectively. Clearance of mucus is aided by using sufficient
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Rezzonico, Fabio. Analysis of stress response and type III secretion system mediated biocontrol in fluorescent pseudomonads protecting plants from soil-borne diseases. 2004.

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Szabo, Sandor, Gary B. Glavin, and Yvette Taché. Neuroendocrinology of Gastrointestinal Ulceration. Springer London, Limited, 2012.

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Hosu, Liana G., and Lori A. Aronson. Hypopituitarism. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199764495.003.0048.

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Hypopituitarism refers to decreased secretion of pituitary hormones, which can result from diseases of the pituitary gland or hypothalamus. Surgery in the presence of untreated panhypopituitarism is rare. It is important to recognize the presence of hypopituitarism and most importantly adrenal insufficiency, a condition that can result in mortality from adrenal crisis without stress-dose corticosteroid treatment.
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Sjoblom, Matthew D., Diane Gordon, and Lori A. Aronson. Hypopituitarism. Edited by Erin S. Williams, Olutoyin A. Olutoye, Catherine P. Seipel, and Titilopemi A. O. Aina. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190678333.003.0041.

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Hypopituitarism is a decreased secretion of pituitary hormones. It is especially concerning during surgery and anesthesia if it results in adrenal insufficiency, hypothyroidism, or diabetes insipidus. Common causes in children include pituitary tumor and/or treatment, traumatic brain injury, and empty sella syndrome. Perioperative management includes recognition of clinical symptoms, such as hypotension, fatigue, polydipsia, and increased urine output. Unrecognized adrenal insufficiency may result in significant morbidity or mortality. Intraoperative treatment may involve stress-dose corticost
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Book chapters on the topic "Secretion stress"

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Dias, Marcos Vinicios Salles, Vilma Regina Martins, and Glaucia Noeli Maroso Hajj. "Stress-Inducible Protein 1 (STI1): Extracellular Vesicle Analysis and Quantification." In Unconventional Protein Secretion. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3804-9_11.

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Genazzani, A. R., F. Petraglia, S. Angioni, et al. "Opioid Control of Gonadotropin Secretion." In Endorphins in Reproduction and Stress. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-75797-6_1.

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Redei, Eva, and Christopher J. Evans. "Dual Control of Corticotropin Secretion: Isolation of Corticotropin-Inhibiting Factor." In Neuropeptides and Stress. Springer New York, 1989. http://dx.doi.org/10.1007/978-1-4612-3514-9_6.

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Szalay, K. SZ. "Effects of β-Endorphin on Adrenocortical Steroid Secretion." In Endorphins in Reproduction and Stress. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-75797-6_13.

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Reichlin, Seymour. "Prolactin and Growth Hormone Secretion in Stress." In Advances in Experimental Medicine and Biology. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4899-2064-5_28.

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Plotsky, Paul M. "Hypophysiotropic Regulation of Stress-Induced ACTH Secretion." In Advances in Experimental Medicine and Biology. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4899-2064-5_6.

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Ammon, H. P. T. "Islet redox state, calcium uptake and insulin secretion: Effects of old age and oxidative stress." In Oxidative Stress and Aging. Birkhäuser Basel, 1995. http://dx.doi.org/10.1007/978-3-0348-7337-6_25.

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Pfeiffer, D. G., and A. Pfeiffer. "Differential Role of μ- and κ-Opiate Receptors in Anterior Pituitary Hormone Secretion." In Endorphins in Reproduction and Stress. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-75797-6_4.

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Hightower, Lawrence E., and Emily J. Noonan. "Discovery of the Cellular Secretion of Cell Stress Proteins." In Heat Shock Proteins. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-4740-1_1.

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Van Loon, Glen R., Judith A. Kiritsy-Roy, Laura V. Brown, and Frances A. Bobbitt. "Nicotinic Regulation of Sympathoadrenal Catecholamine Secretion: Cross-Tolerance to Stress." In Tobacco Smoking and Nicotine. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1911-5_16.

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Conference papers on the topic "Secretion stress"

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Sylar, E., Y. Zhang, A. Vetticaden, A. D. Rice, and T. Wang. "Endotoxin and Mechanical Stress Activate the Biosynthesis and Secretion of Placental Growth Factor." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1978.

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Qi, Pei-shi, Wen-bin Wang, and Zheng Qi. "Effect of Shear Stress on Biofilm Morphological Characteristics and the Secretion of Extracellular Polymeric Substances." In 2008 2nd International Conference on Bioinformatics and Biomedical Engineering (ICBBE '08). IEEE, 2008. http://dx.doi.org/10.1109/icbbe.2008.363.

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Natalini, J., KM Hallow, and SN Ghadiali. "Effect of Fluid Shear Stress and Microbubble Flows on Surfactant Secretion from Alveolar Epithelial Cells." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1235.

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Morise, M., Y. Ito, T. Ohashi, et al. "Unique Effects of Oxidative Stress on cAMP-Mediated Anion Secretion in Human Airway Epithelial Cells." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4940.

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Laustiola, K., R. Lassila, P. Koskinen, and V. Manninen. "GEMFIBROZIL HAS ANTI-PLATELET EFFECTS IN PATIENTS WITH HYPERCHOLESTEROLAEMIA DURING PHYSICAL STRESS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643462.

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Earlier studies indicate an increased platelet reactivity in patients with hypercholesterolaemia. Physical and mental stress have also been reported to cause increased reactivity. The present study was undertaken to evaluate the effect of gemfibrozil (G) a new lipid lowering drug on platelet reactivity during physical stress. Ten otherwise healthy male subjects with serum cholesterol levels above 7 mmol/l were involved in a double-blind study. It consisted of two treatment periods of 8 weeks during which the patients were given either G (600 mg b.i.d.) or placebo (PI) and an 8 weeks wash-out p
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Zhang, Ji, and Morton H. Friedman. "The Adaptive Response of Endothelial Transcription to Increased Shear Stress In Vitro." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19318.

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Previous studies have shown a substantial effect of shear stress on endothelial phenotype and functions such as production of nitric oxide, secretion of growth factors, inflammatory responses, production of reactive oxygen species, permeability to macromolecules and cytoskeletal remodeling [1–3]. However, the dynamics of the endothelial adaptive response to changes in shear stress are largely unknown. The response of vascular endothelial cells to alterations in shear stress is an essential component of normal endothelial physiology, since local shear stress can be altered in vivo by the global
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Karacsonyi, C., N. Shanmugam, and E. Kagan. "Vesicant-Induced Airway Epithelial Cytokine Secretion Is Mediated Via Epidermal Growth Factor Receptor (EGFR) Signaling and Oxidant Stress." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a2818.

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Nomura, Shusaku, Tota Mizuno, Akio Nozawa, Hirotoshi Asano, and Hideto Ide. "The difference in stress induced secretion of an immune substance by the schedule of an intermittent mental workload." In 2008 IEEE International Conference on Systems, Man and Cybernetics (SMC). IEEE, 2008. http://dx.doi.org/10.1109/icsmc.2008.4811264.

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Salinas, M., D. Schmidt, R. Lange, M. Libera, and S. Ramaswamy. "Computational Prediction of Fluid Induced Stress States in Dynamically Conditioned Engineered Heart Valve Tissues." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80787.

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There is extensive documented evidence that mechanical conditioning plays a significant role in the development of tissue grown in-vitro for heart valve scaffolds [1–3]. Modern custom made bioreactors have been used to study the mechanobiology of engineered heart valve tissues [1]. Specifically fluid-induced shears stress patterns may play a critical role in up-regulating extracellular matrix secretion by progenitor cell sources such as bone marrow derived stem cells (BMSCs) [2] and increasing the possibility of cell differentiation towards a heart valve phenotype. We hypothesize that specific
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Pirogov, Aleksey, Irina Andrievskaya, Anna Prikhodko, Viktor Kolosov, and Yuliy Perelman. "PHOSPHATASE ACTIVITY AND POSSIBILITIES OF LYSOSOMAL SECRETION OF AIRWAY NEUTROPHILS IN PATIENTS WITH BRONCHIAL ASTHMA IN COLD-INDUCED STRESS." In XIV International Scientific Conference "System Analysis in Medicine". Far Eastern Scientific Center of Physiology and Pathology of Respiration, 2020. http://dx.doi.org/10.12737/conferencearticle_5fe01d9c3830b9.60748217.

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An approach to the study of cellular inflammation using methods of cytochemical analysis of sputum in patients with bronchial asthma with different types of airway reactions to bronchoprovocation with cold air is presented. Endotyping of patients contributes to a better understanding of the pathophysiological mechanisms and the choice of treatment tactics for the disease.
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Reports on the topic "Secretion stress"

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El Halawani, Mohamed, and Israel Rozenboim. Temperature Stress and Turkey Reproduction. United States Department of Agriculture, 2002. http://dx.doi.org/10.32747/2002.7570546.bard.

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High temperature stress is of major concern to turkey producers in Israel and the United States. The decline in the rate of egg production at high environmental temperature is well recognized, but the neuroendocrinological basis is not understood. Our objectives were: 1) to characterize the hypothalamo-hypophyseal axis involvement in the mechanism(s) underlying the detrimental effect of heat stress on reproduction, and 2) to establish procedures that alleviate the damaging effect of heat stress on reproduction. Heat stress (40oC, Israel; 32oC, U.S.) caused significant reduction in egg producti
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Elbaum, Michael, and Peter J. Christie. Type IV Secretion System of Agrobacterium tumefaciens: Components and Structures. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7699848.bard.

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Objectives: The overall goal of the project was to build an ultrastructural model of the Agrobacterium tumefaciens type IV secretion system (T4SS) based on electron microscopy, genetics, and immunolocalization of its components. There were four original aims: Aim 1: Define the contributions of contact-dependent and -independent plant signals to formation of novel morphological changes at the A. tumefaciens polar membrane. Aim 2: Genetic basis for morphological changes at the A. tumefaciens polar membrane. Aim 3: Immuno-localization of VirB proteins Aim 4: Structural definition of the substrate
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Christopher, David A., and Avihai Danon. Plant Adaptation to Light Stress: Genetic Regulatory Mechanisms. United States Department of Agriculture, 2004. http://dx.doi.org/10.32747/2004.7586534.bard.

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Original Objectives: 1. Purify and biochemically characterize RB60 orthologs in higher plant chloroplasts; 2. Clone the gene(s) encoding plant RB60 orthologs and determine their structure and expression; 3. Manipulate the expression of RB60; 4. Assay the effects of altered RB60 expression on thylakoid biogenesis and photosynthetic function in plants exposed to different light conditions. In addition, we also examined the gene structure and expression of RB60 orthologs in the non-vascular plant, Physcomitrella patens and cloned the poly(A)-binding protein orthologue (43 kDa RB47-like protein).
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Sela, Shlomo, and Michael McClelland. Investigation of a new mechanism of desiccation-stress tolerance in Salmonella. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7598155.bard.

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Low-moisture foods (LMF) are increasingly involved in foodborne illness. While bacteria cannot grow in LMF due to the low water content, pathogens such as Salmonella can still survive in dry foods and pose health risks to consumer. We recently found that Salmonella secretes a proteinaceous compound during desiccation, which we identified as OsmY, an osmotic stress response protein of 177 amino acids. To elucidate the role of OsmY in conferring tolerance against desiccation and other stresses in Salmonella entericaserovarTyphimurium (STm), our specific objectives were: (1) Characterize the invo
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Wolfenson, David, William W. Thatcher, and James E. Kinder. Regulation of LH Secretion in the Periovulatory Period as a Strategy to Enhance Ovarian Function and Fertility in Dairy and Beef Cows. United States Department of Agriculture, 2003. http://dx.doi.org/10.32747/2003.7586458.bard.

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The general research objective was to increase herd pregnancy rates by enhancing corpus luteum (CL) function and optimizing follicle development, in order to increase conception rate and embryo survival. The specific objectives were: to determine the effect of the duration of the preovulatory LH surge on CL function; to determine the function of LH during the postovulatory period on CL development; to optimize CL differentiation and follicle development by means of a biodegradable GnRH implant; to test whether optimization of CL development and follicle dynamics in timed- insemination protocol
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Dahl, Geoffrey E., Sameer Mabjeesh, Thomas B. McFadden, and Avi Shamay. Environmental manipulation during the dry period of ruminants: strategies to enhance subsequent lactation. United States Department of Agriculture, 2006. http://dx.doi.org/10.32747/2006.7586544.bard.

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The project resulted from earlier observations that environmental factors, especially photoperiod and temperature, had profound effects on milk yield in dairy cattle during lactation. More recently we had determined that photoperiod manipulation during the dry period altered milk yield in the next lactation, and this was associated with shifts in circulating concentrations of prolactin; specifically exposure to short days during the dry period decreases prolactin but increases milk yield. Because prolactin is also affected by temperature, with heat stress causing an increase in prolactin simil
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Elmann, Anat, Orly Lazarov, Joel Kashman, and Rivka Ofir. therapeutic potential of a desert plant and its active compounds for Alzheimer's Disease. United States Department of Agriculture, 2015. http://dx.doi.org/10.32747/2015.7597913.bard.

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We chose to focus our investigations on the effect of the active forms, TTF and AcA, rather than the whole (crude) extract. 1. To establish cultivation program designed to develop lead cultivar/s (which will be selected from the different Af accessions) with the highest yield of the active compounds TTF and/or achillolide A (AcA). These cultivar/s will be the source for the purification of large amounts of the active compounds when needed in the future for functional foods/drug development. This task was completed. 2. To determine the effect of the Af extract, TTF and AcA on neuronal vulnerabi
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Lichter, Amnon, Gopi K. Podila, and Maria R. Davis. Identification of Genetic Determinants that Facilitate Development of B. cinerea at Low Temperature and its Postharvest Pathogenicity. United States Department of Agriculture, 2011. http://dx.doi.org/10.32747/2011.7592641.bard.

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Botrytis cinerea is the postharvest pathogen of many agricultural produce with table grapes, strawberries and tomatoes as major targets. The high efficiency with which B. cinerea causes disease on these produce during storage is attributed in part due to its exceptional ability to develop at very low temperature. Our major goal was to understand the genetic determinants which enable it to develop at low temperature. The specific research objectives were: 1. Identify expression pattern of genes in a coldenriched cDNA library. 2. Identify B. cinerea orthologs of cold-induced genes 3. Profile pro
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Ron, Eliora, and Eugene Eugene Nester. Global functional genomics of plant cell transformation by agrobacterium. United States Department of Agriculture, 2009. http://dx.doi.org/10.32747/2009.7695860.bard.

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The aim of this study was to carry out a global functional genomics analysis of plant cell transformation by Agrobacterium in order to define and characterize the physiology of Agrobacterium in the acidic environment of a wounded plant. We planed to study the proteome and transcriptome of Agrobacterium in response to a change in pH, from 7.2 to 5.5 and identify genes and circuits directly involved in this change. Bacteria-plant interactions involve a large number of global regulatory systems, which are essential for protection against new stressful conditions. The interaction of bacteria with
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