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1

Center, Oregon Prevention Resource, and National Institute on Drug Abuse., eds. Sedative-hypnotics. Oregon Prevention Resource Center, Office of Alcohol and Drug Abuse Programs, Dept. of Human Resources, 1997.

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2

Center, Oregon Prevention Resource, and National Institute on Drug Abuse., eds. Sedative-hypnotics. Oregon Prevention Resource Center, Office of Alcohol and Drug Abuse Programs, Dept. of Human Resources, 1997.

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3

G, Whitwam J., ed. Principles and practice of sedation. Blackwell Science, 1998.

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4

Scott, Celicia. Dangerous Depressants & Sedatives. Mason Crest, 2015.

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5

D, Ross Barbara Ph, ed. Anaesthetic and sedative techniques for aquatic animals. 2nd ed. Blackwell Science, 1999.

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6

NIH Consensus Development Conference Anesthesia and Sedation in the Dental Office (1985 Bethesda, Md.). Anesthesia and sedation in the dental office. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, Office of Medical Applications of Research, 1985.

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7

Kenton, Charlotte. Dental anesthesia and sedation: January 1980 through April 1985 : 406 citations in English. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, 1985.

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8

Institute of Medicine (U.S.). Committee on Halcion: An Assessment of Data Adequacy and Confidence. Halcion: An independent assessment of safety and efficacy data. National Academy Press, 1997.

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9

Anthony, Kales, ed. The pharmacology of sleep. Springer, 1995.

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10

Workshop on "Target Receptors for Anxiolytics and Hypnotics: From Molecular Pharmacology to Therapeutics" (1991 Monte-Carlo, Monaco). Target receptors for anxiolytics and hypnotics: From molecular pharmacology to therapeutics : Workshop on "Target Receptors for Anxiolytics and Hypnotics: From Molecular Pharmacology to Therapeutics," Monte Carlo, November 24-26, 1991. Edited by Mendlewicz J and Racagni Giorgio. Karger, 1992.

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11

Morgan, Kevin. Sleep and aging: A research-based guide to sleep in later life. Johns Hopkins University Press, 1987.

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12

Jaap, Vuyk, Engbers Frank H. M, and Groen-Mulder Sandra M, eds. On the study and practice of intravenous anaesthesia. Kluwer Academic Publishers, 2000.

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13

P, Sauvanet J., Langer S. Z, Morselli Paolo Lucio, and Laboratoires d'études et de recherches Synthélabo., eds. Imidazopyridines in sleep disorders: A novel experimental and therapeutic approach. Raven Press, 1988.

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14

Liñán, Carmen García. Depresores. Árbol Editorial, 1990.

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15

Rees, Gayla, Benjamin Shapiro, and Matthew Torrington. Integrative Approach to Sedative-Hypnotic Use Disorder. Edited by Shahla J. Modir and George E. Muñoz. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190275334.003.0005.

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Sedatives, hypnotics, and anxiolytics are CNS depressants with GABAergic activity that are potentially habit-forming due to their activity in brain reward pathways. They are central in the drug overdose epidemic with benzodiazepines (BZD) being involved in approximately 31% of all fatal overdoses. There are 4 withdrawal syndromes: High dose minor and major withdrawal, low dose withdrawal, and protracted withdrawal. Benzodiazepines are chemically related positive allosteric modulators of the GABA at the GABA-A receptor. In differential expression 5 different receptor subunits play a role in acu
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16

Williams, Arthur Robin, and Olivera J. Bogunovic. Benzodiazepines and Other Sedative-Hypnotics in the Older Adult. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199392063.003.0007.

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Sedative-hypnotic-use disorder is a serious problem in the elderly and is a growing concern in the United States. The American Geriatrics Society’s “Choosing Wisely” initiative cautions against the use of any benzodiazepines or other sedative-hypnotics as initial treatment in older adults, yet benzodiazepines are the most frequently prescribed drugs in the elderly for both insomnia and anxiety. Other classes of medication (e.g., serotoninergic antidepressants) may be substituted for benzodiazepines based on diagnosis. With advancing age, the elderly are more sensitive to the potential side eff
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17

Jasinski, D. R. Drug Addiction I: Morphine, Sedative/Hypnotic and Alcohol Dependence. Springer, 2013.

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18

Conrad, H. T., H. F. Fraser, and C. W. Gorodetzky. Drug Addiction I: Morphine, Sedative/Hypnotic and Alcohol Dependence. Springer, 2011.

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19

Sinha, Shirshendu. Substance-Related Disorders. Edited by Rajiv Radhakrishnan and Lily Arora. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190265557.003.0016.

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This chapter reviews topics on substance-related disorders including alcohol-related disorders, stimulant-related disorders, caffeine-related disorders, cannabis-related disorders, stimulant-related disorders, hallucinogen-related disorders, tobacco-related disorders, opioid-related disorders, phencyclidine-related disorders and sedative-, hypnotic-, or anxiolytic-related disorders
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20

Colameco, Stephen. Pain and Addiction in Patients with Co-Occurring Medical Disorders (DRAFT). Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190265366.003.0026.

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Distinct from Chapter 24, on co-occurring psychiatric disorders, this chapter addresses common physical comorbidities that give rise to chronic pain and are notorious for associated substance use disorders. The concept of “pseudo-addiction” is explored as one of several contributors to common misperceptions of the analgesic needs of such patients. Examples of entities discussed are chronic low back pain, sleep apnea, chronic pancreatitis, cirrhosis, and HIV infection or AIDS-related pain. While not intrinsically painful, sleep apnea merits inclusion as it arises in conjunction with sedative-hy
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21

Pangarkar, Sanjog S. Pain and Addiction in Patients with Traumatic Brain Injury (DRAFT). Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190265366.003.0027.

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Distinct from Chapter 24, on co-occurring psychiatric disorders, this chapter addresses common physical comorbidities that give rise to chronic pain and are notorious for associated substance use disorders. The concept of “pseudo-addiction” is explored as one of several contributors to common misperceptions of the analgesic needs of such patients. Examples of entities discussed are chronic low back pain, sleep apnea, chronic pancreatitis, cirrhosis, and HIV infection or AIDS-related pain. While not intrinsically painful, sleep apnea merits inclusion as it arises in conjunction with sedative-hy
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22

Absalom, Anthony, and John Sear. Intravenous anaesthetics. Edited by Michel M. R. F. Struys. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0015.

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In recent decades, increasing attention has been focused on the intravenous anaesthetic agents. This interest has been stimulated by the discovery and availability of agents with increasingly favourable pharmacokinetic and dynamic properties, coupled with advances in knowledge of pharmacology and advances in computer technology. For most patients and operative procedures, anaesthesia is induced with a bolus or fast infusion of a short-acting drug, most commonly propofol. Increasingly, anaesthesia is thereafter also maintained with an infusion of an agent with favourable kinetics, again usually
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23

Sedatives And Hypnotics Deadly Downers. Mason Crest Publishers, 2012.

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24

Walker, Ida. Sedatives and Hypnotics: Deadly Downers. Mason Crest, 2014.

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25

Walker, Ida. Sedatives & Hypnotics: Dangerous Downers (Illicit Drugs). Mason Crest Publishers, 2007.

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26

Hendrickson, Rebecca C., and Murray A. Raskind. Pharmacological Treatment of Nightmares, Sleep Disturbance, and Daytime Hyperarousal in PTSD: The Role of Prazosin, Other Noradrenergic Modulators, and Sedative Hypnotics or Commonly Used Sedating Medications. Edited by Charles B. Nemeroff and Charles R. Marmar. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190259440.003.0035.

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Disruption of stress-response systems contributes to the pathophysiology of post-traumatic stress disorder (PTSD). Consistent with this, daytime hyperarousal and nighttime sleep disruption, including trauma-related nightmares, are core symptoms of the disorder, often requiring targeted pharmacologic treatment. Although a variety of medications that target sleep–wake and arousal mechanisms are commonly used for this purpose, there remains the best empirical support for prazosin, a brain-active antagonist of the α‎1 noradrenaline receptor, with emerging evidence for doxazosin, a longer-acting me
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27

Scott, Celicia. Dangerous Depressants and Sedatives. Mason Crest, 2014.

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28

Ross, Lindsay, Barbara Ross, and Ross Barbara. Anaesthesia and Sedative Techniques for Fish. Blackwell Publishing Limited, 2000.

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29

Glass, Jennifer. Risk-benefit relationship of sedative-hypnotics in elderly individuals with insomnia. 2005.

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30

Ross, Lindsay, and Barbara Ross. Anaesthetic and Sedative Techniques for Aquatic Animals. Wiley & Sons, Limited, John, 2009.

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31

Ross, Barbara, and Lindsay G. Ross. Anaesthetic and Sedative Techniques for Aquatic Animals. Wiley & Sons, Incorporated, John, 2009.

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32

Ross, Barbara, and Lindsay G. Ross. Anaesthetic and Sedative Techniques for Aquatic Animals. Wiley & Sons, Limited, John, 2009.

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33

Ross, Lindsay, and Barbara Ross. Anaesthetic and Sedative Techniques for Aquatic Animals. Wiley & Sons, Limited, John, 1999.

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34

The 2006-2011 World Outlook for Prescription Barbituate Anxiolytic and Hypnotic Sedatives. Icon Group International, Inc., 2005.

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35

Parker, Philip M. The 2007-2012 World Outlook for Prescription Barbituate Anxiolytic and Hypnotic Sedatives. ICON Group International, Inc., 2006.

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36

Gupta, Neha. Treatment of Psychiatric Disorders. Edited by Isis Burgos-Chapman. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190265557.003.0006.

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In this chapter, essential aspects of the treatment of psychiatric disorders are reviewed including pharmacokinetics, pharmacodynamics, drug interactions, psychogenomics and the use of antidepressants, mood stabilizers, antianxiety agents, antipsychotics, psychostimulants, hypnotics and sedatives, ECT and psychotherapy
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37

Singh, Harvinder, Miyun Kang, Sarah de Asis, et al. Treatment of Psychiatric Disorders. Edited by Rajiv Radhakrishnan and Lily Arora. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190265557.003.0028.

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In this chapter the treatment of psychiatric disorders are reviewed including antidepressants, mood stabilizers, antianxiety agents, antipsychotics, psychostimulants, hypnotics, sedatives, electroconvulsive therapy, vagal nerve stimulation, psychotherapy, repetitive transcranial nerve stimulation (rTMS), vagal nerve stimulation and self-help groups
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38

Parker, Philip M. The 2007-2012 Outlook for Prescription Barbituate Anxiolytic and Hypnotic Sedatives in Japan. ICON Group International, Inc., 2006.

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39

Nadell, Reyna. Sedatives and Hypnotics : Pain Management Without Drugs: Pain Relief for Wisdom Teeth. Independently Published, 2021.

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40

Parker, Philip M. The 2007-2012 Outlook for Prescription Non-Barbituate Anxiolytic and Hypnotic Sedatives in India. ICON Group International, Inc., 2006.

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41

Parker, Philip M. The 2007-2012 Outlook for Prescription Barbituate Anxiolytic and Hypnotic Sedatives in Greater China. ICON Group International, Inc., 2006.

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42

Parker, Philip M. The 2007-2012 Outlook for Prescription Non-Barbituate Anxiolytic and Hypnotic Sedatives in Japan. ICON Group International, Inc., 2006.

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43

Monton, Edgar A. Tranquillizers and Hypnotics (Roseneath Popular Medical Booklets). 3rd ed. Roseneath Scientific Pubns., 2000.

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44

Parker, Philip M. The 2007-2012 Outlook for Prescription Non-Barbituate Anxiolytic and Hypnotic Sedatives in Greater China. ICON Group International, Inc., 2006.

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45

Parker, Philip M. The 2007-2012 Outlook for Prescription Barbituate Anxiolytic and Hypnotic Sedatives in the United States. ICON Group International, Inc., 2006.

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46

Herndon, Christopher M., and Kelly N. Gable. An Overview of the Abuse Potential of Nonopioids. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199981830.003.0006.

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Discussions of the abuse of prescription medications have been overshadowed by the abuse of opioids. However, numerous other medications, in very different classes and for very different reasons, are abused as well. Sedative-hypnotics (e.g., benzodiazepines), barbiturates, antipsychotics, and muscle relaxants are just some of the medications that are abused and misused. It is critical to keep in mind that the opioid crisis is magnified by the abuse of these other medications. This chapter gives a succinct and clear overview of some of these other classes of medications and how they are abused.
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47

Parker, Philip M. The 2007-2012 Outlook for Prescription Non-Barbituate Anxiolytic and Hypnotic Sedatives in the United States. ICON Group International, Inc., 2006.

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48

Mendelson, Wallace B. Use and Misuse of Sleeping Pills: A Clinical Guide. Springer, 2012.

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49

Mendelson, Wallace B. Use and Misuse of Sleeping Pills: A Clinical Guide. Springer London, Limited, 2012.

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50

Parker, Philip M. The 2007-2012 Outlook for Non-Prescription Anxiolytic, Hypnotic, and Sleep-Inducing Sedatives Excluding Antihistamines in India. ICON Group International, Inc., 2006.

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