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Books on the topic 'Signalling pathway'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Bhimani, Munsif Ali. Detecting mediators of the Flk-1 signalling pathway by mRNA differential display. National Library of Canada, 1998.

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2

Nguyen, Melody Hong Hanh. TEL-Jak2 chromosomal translocations and the PI3' kinase and PKB signalling pathway. National Library of Canada, 2000.

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3

Rizza, Annalisa. Identification of components in the BBX24 light signalling pathway in Arabidopsis thaliana. s.n.], 2013.

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4

O, Pickens Charles, ed. Cell apoptotic signalling pathways. Nova Biomedical Books, 2007.

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5

1943-, Lavin Martin, and Watters Dianne 1952-, eds. Signalling pathways in apoptosis. Harwood Academic, 1999.

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6

Chadwick, Derek J., and Jamie Goode, eds. Signalling Pathways in Acute Oxygen Sensing. John Wiley & Sons, Ltd, 2006. http://dx.doi.org/10.1002/9780470035009.

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7

Foundation, Novartis. Signalling Pathways in Acute Oxygen Sensing. John Wiley & Sons, Ltd., 2006.

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8

Tuominen-Gustafsson, Helena Birgitta. Calcium signalling pathways in human neutrophils. Åbo Akademis Förlag, 1998.

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9

Symposium on Signalling Pathways in Acute Oxygen Sensing (2005 Novartis Foundation). Signalling pathways in acute oxygen sensing. John Wiley, 2006.

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10

Dua, Kamal, Raimar Löbenberg, Ângela Cristina Malheiros Luzo, Shakti Shukla, and Saurabh Satija, eds. Targeting Cellular Signalling Pathways in Lung Diseases. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-33-6827-9.

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11

Lo Schiavo, Fiorella, Robert L. Last, Giorgio Morelli, and Natasha V. Raikhel, eds. Cellular Integration of Signalling Pathways in Plant Development. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-72117-5.

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12

Sheldon, Katherine. Cell signalling pathways: Productive sources of pharmaceutical targets. D & MD Publications, 2004.

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13

Taha, Celia. Signalling pathways regulating glucose transporter expression in muscle cells. National Library of Canada, 1996.

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14

Patel, Nayan Govindbhai. Signalling pathways important in human adipose tissue growth and function. University of Birmingham, 2003.

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15

Yang, Shen-Hsui. Insulin signalling pathways involved in selective control of hepatic gene expression. University of Manchester, 1995.

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16

Sittaro, Dino. c-Kit signalling pathways and survival signals in a factor-dependent leukemia. National Library of Canada, 2000.

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17

Kekkonen, Viktoria. Characterization of bacterial RNA and DNA signalling pathways that induce cellular dysfunction. Laurentian University, 2006.

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18

Yule, Jennifer M. Phosphatidylcholine and sphingomyelin signalling pathways in the control of proliferation and differentiation. University of Birmingham, 1996.

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19

Woods, Stacy Ann. Signalling pathways regulating expression of vascular endothelial growth factor in human malignant astrocytomas. National Library of Canada, 2001.

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20

Derek, Chadwick, Goode Jamie, and Novartis Foundation, eds. Signalling pathways in acute oxygen sensing.: [editors Derek J. Chadwick and Jamie Goode]. John Wiley, 2006.

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21

Radford, David John. Investigation of neutrophil signalling pathways activated by autoantibodies (ANCA) from patients with systemic vasculitis. University of Birmingham, 1998.

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22

Perkins, Jonathan Edwards. A study of EGF-induced intracellular signalling pathways and effects in first trimester trophoblast. University of Birmingham, 2003.

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23

Brant, Dawn Patricia. The signalling pathways involved in thrombin-induced morphological change and DNA synthesis in human neuroepithelial cells. University of Birmingham, 1997.

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24

Conroy, Louise Anne. The development of t-lymphocytes within the murine foetal thymus: The role of intracellular signalling pathways. University of Birmingham, 1992.

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25

Fleischmann, Roy. Signalling pathway inhibitors. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0081.

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Oral, small-molecule signalling pathway inhibitors, including ones that inhibit the JAK and SyK pathways, are currently in development for the treatment of rheumatoid arthritis (RA). Tofacitinib is an orally administered small-molecule inhibitor that targets the intracellular Janus kinase 3 and 1 (JAK1/3) molecules to a greater extent than JAK2 while baricitinib (formerly INCB028050) predominantly inhibits JAK1/2. Many of the proinflammatory cytokines implicated in the pathogenesis of RA utilize cell signalling that involves the JAK-STAT pathways and therefore inhibition of JAK-STAT signalling

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26

Leroith, Derek. Jnk Signalling Pathway. Eurekah.com, Inc., 2006.

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27

Lam, Eric W.-F. Phosphoinositide 3-Kinase Signalling Pathway. PUBLISHED BY IMPERIAL COLLEGE PRESS AND DISTRIBUTED BY WORLD SCIENTIFIC PUBLISHING CO., 2006. http://dx.doi.org/10.1142/p428.

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28

Cheng, Zhiyong. Nutritional Signalling Pathway Activities in Obesity and Diabetes. Royal Society of Chemistry, The, 2020.

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29

Cheng, Zhiyong. Nutritional Signalling Pathway Activities in Obesity and Diabetes. Royal Society of Chemistry, The, 2020.

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30

Jakstat Signalling Methods And Protocols. Humana Press, 2012.

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31

Kockeritz, Lisa Karen. Roles of Wnt signalling pathway components in embryonic development and disease. 2005.

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32

Phosphoinositide 3-kinase Signalling Pathway: The Key to Cell Proliferation And Death. Imperial College Press, 2006.

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33

Kavsak, Peter. Smurfs are E3 ubiquitin protein ligases that inhibit the transforming growth factor beta signalling pathway. 2001.

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34

Zaffran, Stéphane. Cardiac growth II: Cardiomyocyte polarization. Edited by José Maria Pérez-Pomares, Robert G. Kelly, Maurice van den Hoff, et al. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757269.003.0010.

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During vertebrate embryogenesis, the planar cell polarity (PCP) signalling pathway is responsible for cell movements essential for convergent extension during gastrulation, neural tube closure, neural crest cell migration, and heart morphogenesis. In the heart, the non-canonical Wnt/PCP pathway regulates cell polarity, cell shape, and cell dynamics during formation of the cardiac crescent and deployment of second heart field cardiac progenitors to the poles of the heart tube. PCP signalling is also essential for the establishment of left–right patterning in the early embryo. This chapter revie

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35

D’Amato, Gaetano, Guillermo Luxán, and José Luis de la Pompa. Defining cardiac domains from the inside: NOTCH in endocardial–myocardial interactions. Edited by José Maria Pérez-Pomares, Robert G. Kelly, Maurice van den Hoff, et al. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757269.003.0011.

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In this chapter we illustrate the signalling interactions of the endocardium with the other cardiac tissues to coordinate cardiac development. First, we describe the developmental origins of the endocardium. Then we focus on the Notch pathway because of its unique signalling activity in the endocardium, and briefly describe the elements of this signalling mechanism and the key cardiogenic processes that require endocardial Notch signalling: patterning of the early embryonic endocardium into prospective territories for valves and ventricular chambers, early valve formation, ventricular trabecul

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36

Hodgkiss, Andrew. Introduction to cancer biology. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198759911.003.0001.

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A brief introduction to cancer biology, aimed at psychiatrists, is offered. Selective DNA transcription, the cell cycle, receptor tyrosine kinases, and cell signalling pathways are introduced, using the EGFR/RAS/MAPK pathway as an exemplar. The molecular pathology of oncogenesis is summarized, including discussion of oncogenes, tumour suppressor genes, and examples of driver mutations. The exploitation of such mutations in stratified medicine, using molecularly targeted agents, is mentioned. Finally, Hanahan and Weinberg’s six hallmarks of cancer are listed, adding angiogenesis and metastasis

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37

Alves, Ines Teles, Jan Trapman, and Guido Jenster. Molecular biology of prostate cancer. Edited by James W. F. Catto. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0059.

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Prostate cancer is a heterogeneous disease that arises through the acquisition of key malignant hallmarks. At the molecular level, prostate tumours are dependent upon the androgen receptor pathway, which affects cell function, growth, and behaviour through downstream androgen-regulated genes. Prostate cancer requires this activity and manipulates the AR pathway to maintain signalling. For example, mutation of the AR (to bind ligands other than androgens) or amplification/duplication of the AR allows signalling to continue in the absence of testosterone. Around 50% of prostate cancers have a ge

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38

1st, Gupta Sudhir Kumar. Multilevel Signalling Pathways. Alexis Press LLC, 2022.

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39

Lavin, Martin, and Diane Watters. Signalling Pathways in Apoptosis. Taylor & Francis Group, 1999.

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40

Pickens, Charles O. Cell Apoptotic Signalling Pathways. Nova Science Pub Inc, 2006.

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41

Lavin, Martin, and Diane Watters. Signalling Pathways in Apoptosis. Taylor & Francis Group, 1999.

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42

Watters, Dianne, and Martin Lavin. Signalling Pathways in Apoptosis. Taylor & Francis Group, 1999.

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43

Kühn, Wolfgang, and Gerd Walz. The molecular basis of ciliopathies and cyst formation. Edited by Neil Turner. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0303.

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Abnormalities of the cilium, termed ‘ciliopathies’, are the prime suspect in the pathogenesis of renal cyst formation because the gene products of cystic disease-causing genes localize to them, or near them. However, we only partially understand how cilia maintain the geometry of kidney tubules, and how abnormal cilia lead to renal cysts, and the diverse range of diseases attributed to them. Some non-cystic diseases share pathology of the same structures. Although still incompletely understood, cilia appear to orient cells in response to extracellular cues to maintain the overall geometry of a

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44

Sanz-Ezquerro, Juan J., Andrea E. Münsterberg, and Sigmar Stricker, eds. Signalling Pathways in Embryonic Development. Frontiers Media SA, 2017. http://dx.doi.org/10.3389/978-2-88945-346-7.

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45

Lacal, Carlos. Signalling Pathways in Abiotic Stress. Arcler Education Inc, 2017.

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46

Goode, Jamie A., and Derek J. Chadwick. Signalling Pathways in Acute Oxygen Sensing. Wiley & Sons, Incorporated, John, 2009.

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47

Novartis, Foundation. Signalling Pathways in Acute Oxygen Sensing. Wiley & Sons, Incorporated, John, 2006.

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48

Goode, Jamie A., Derek J. Chadwick, and Novartis Foundation Staff. Signalling Pathways in Acute Oxygen Sensing. Wiley & Sons, Limited, John, 2007.

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49

Brown, Matthew. Genetics of spondyloarthropathies. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0041.

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Spondyloarthropathies are a diverse group of conditions, of which ankylosing spondylitis is the prototypic disease, with shared clinical features, genetic risk factors, and histopathological characteristics. These conditions are highly familial and heritable. Several genes have been associated with spondyloarthropathies, with genes in the IL-23 signalling pathway being shared by the major types of spondyloarthritis. These discoveries have already led to the development and successful clinical introduction of novel treatments for psoriasis and psoriatic arthritis, and major advances in our unde

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50

Brown, Matthew. Genetics of spondyloarthropathies. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199642489.003.0041_update_003.

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Spondyloarthropathies are a diverse group of conditions, of which ankylosing spondylitis is the prototypic disease, with shared clinical features, genetic risk factors, and histopathological characteristics. These conditions are highly familial and heritable. Several genes have been associated with spondyloarthropathies, with genes in the IL-23 signalling pathway being shared by the major types of spondyloarthritis. These discoveries have already led to the development and successful clinical introduction of novel treatments for psoriasis and psoriatic arthritis, and major advances in our unde

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