Academic literature on the topic 'Stem progenitor cell'

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Journal articles on the topic "Stem progenitor cell"

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Carpino, Guido, Anastasia Renzi, Antonio Franchitto, et al. "Stem/Progenitor Cell Niches Involved in Hepatic and Biliary Regeneration." Stem Cells International 2016 (2016): 1–12. http://dx.doi.org/10.1155/2016/3658013.

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Niches containing stem/progenitor cells are present in different anatomical locations along the human biliary tree and within liver acini. The most primitive stem/progenitors, biliary tree stem/progenitor cells (BTSCs), reside within peribiliary glands located throughout large extrahepatic and intrahepatic bile ducts. BTSCs are multipotent and can differentiate towards hepatic and pancreatic cell fates. These niches’ matrix chemistry and other characteristics are undefined. Canals of Hering (bile ductules) are found periportally and contain hepatic stem/progenitor cells (HpSCs), participating
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Hu, Wen-Yang, Dan-Ping Hu, Lishi Xie, et al. "Keratin Profiling by Single-Cell RNA-Sequencing Identifies Human Prostate Stem Cell Lineage Hierarchy and Cancer Stem-Like Cells." International Journal of Molecular Sciences 22, no. 15 (2021): 8109. http://dx.doi.org/10.3390/ijms22158109.

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Single prostate stem cells can generate stem and progenitor cells to form prostaspheres in 3D culture. Using a prostasphere-based label retention assay, we recently identified keratin 13 (KRT13)-enriched prostate stem cells at single-cell resolution, distinguishing them from daughter progenitors. Herein, we characterized the epithelial cell lineage hierarchy in prostaspheres using single-cell RNA-seq analysis. Keratin profiling revealed three clusters of label-retaining prostate stem cells; cluster I represents quiescent stem cells (PSCA, CD36, SPINK1, and KRT13/23/80/78/4 enriched), while clu
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Pereira, Joao P., Vivian Lim, Ana Gomes, et al. "Hematopoietic stem cell niches control multipotent progenitor differentiation." Journal of Immunology 196, no. 1_Supplement (2016): 122.1. http://dx.doi.org/10.4049/jimmunol.196.supp.122.1.

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Abstract Hematopoietic stem cells (HSC) self-renew in bone marrow niches formed by CXCL12+ mesenchymal progenitor and endothelial cells. Here, we show that hematopoietic multipotent progenitors (MPPs) encounter lineage-instructive differentiation signals in HSC niches. Conditional deletion of CXCR4 in MPPs profoundly reduced differentiation into common lymphoid progenitors (CLPs), which significantly decreased lymphopoiesis. CXCR4 was required for CLP positioning near IL-7+ cells and, consequently, for optimal IL-7R signaling. IL-7+ cells form a large subset of CXCL12-abundant reticular mesenc
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Meier‐Abt, F., S. Amon, L. Gillet, et al. "PF453 TRANSCRIPTOME‐PROTEOME CORRELATION IN HUMAN HEMATOPOIETIC STEM AND PROGENITOR CELLS." HemaSphere 3, S1 (2019): 178. http://dx.doi.org/10.1002/j.2572-9241.2019.tb00052.x.

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Background:Hematopoietic stem cells (HSCs) can self‐renew and/or differentiate into various functionally divergent progenitor cell types, such as common myeloid progenitors (CMPs), megakaryocyte‐erythrocyte progenitors (MEPs) or granulocyte‐macrophage progenitors (GMPs). When the process of self‐renewal and differentiation is altered, e.g. upon genetic or epigenetic changes in HSCs, abnormal (pre)leukemic stem cell subpopulations may form, eventually resulting in the onset of hematopoietic malignancies. To gain insight into the physiology and patho‐physiology of self‐renewal and differentiatio
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Kuramoto, Ken, Dean A. Follmann, Peiman Hematti, et al. "Effect of chronic cytokine therapy on clonal dynamics in nonhuman primates." Blood 103, no. 11 (2004): 4070–77. http://dx.doi.org/10.1182/blood-2003-08-2934.

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Abstract Hematopoietic cytokines such as filgrastim are used extensively to stimulate granulocyte production or to mobilize hematopoietic progenitors into the circulation; however, their effect on more primitive hematopoietic progenitor and stem cells in vivo is unknown, particularly in large animals or humans. In particular, there is concern that chronic therapy with cytokines could result in stem cell exhaustion or clonal dominance; however, direct assessment of the dynamics of individual stem and progenitor cell clones in vivo has not been previously reported. A number of models can be prop
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Qian, Hong, Karl Tryggvason, Sten Eirik Jacobsen та Marja Ekblom. "Contribution of α6 integrins to hematopoietic stem and progenitor cell homing to bone marrow and collaboration with α4 integrins". Blood 107, № 9 (2006): 3503–10. http://dx.doi.org/10.1182/blood-2005-10-3932.

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The laminin receptor integrin α6 chain is ubiquitously expressed in human and mouse hematopoietic stem and progenitor cells. We have studied its role for homing of stem and progenitor cells to mouse hematopoietic tissues in vivo. A function-blocking anti–integrin α6 antibody significantly reduced progenitor cell homing to bone marrow (BM) of lethally irradiated mice, with a corresponding retention of progenitors in blood. Remarkably, the anti–integrin α6 antibody profoundly inhibited BM homing of long-term multilineage engrafting stem cells, studied by competitive repopulation assay and analys
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Ribatti, Domenico, and Antonio d’Amati. "Hematopoiesis and Mast Cell Development." International Journal of Molecular Sciences 24, no. 13 (2023): 10679. http://dx.doi.org/10.3390/ijms241310679.

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Hematopoietic stem cells (HSCs) are defined based on their capacity to replenish themselves (self-renewal) and give rise to all mature hematopoietic cell types (multi-lineage differentiation) over their lifetime. HSCs are mainly distributed in the bone marrow during adult life, harboring HSC populations and a hierarchy of different kinds of cells contributing to the “niche” that supports HSC regulation, myelopoiesis, and lymphopoiesis. In addition, HSC-like progenitors, innate immune cell precursors such as macrophages, mast cells, natural killer cells, innate lymphoid cells, and megakaryocyte
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Camargo, Fernando D. "In vivo Stem Cell Clonal Dynamics." Blood 126, no. 23 (2015): SCI—40—SCI—40. http://dx.doi.org/10.1182/blood.v126.23.sci-40.sci-40.

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Abstract Tremendous progress has been achieved in the characterization of the hematopoietic system over the past two decades. Historically, the main experimental approach used to elucidate and define these cellular relationships in the bone marrow (BM) has been the transplantation assay. For this reason, most of our knowledge about the in vivo properties of hematopoietic stem cells (HSCs) and progenitor cells has been derived from studies in the transplant context. Because of the lack of tractable systems, the mechanistic nature of non-transplant hematopoiesis has remained largely unexplored.
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Quesenberry, Peter J., Gerald A. Colvin, and Jean-Francois Lambert. "The chiaroscuro stem cell: a unified stem cell theory." Blood 100, no. 13 (2002): 4266–71. http://dx.doi.org/10.1182/blood-2002-04-1246.

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Hematopoiesis has been considered hierarchical in nature, but recent data suggest that the system is not hierarchical and is, in fact, quite functionally plastic. Existing data indicate that engraftment and progenitor phenotypes vary inversely with cell cycle transit and that gene expression also varies widely. These observations suggest that there is no progenitor/stem cell hierarchy, but rather a reversible continuum. This may, in turn, be dependent on shifting chromatin and gene expression with cell cycle transit. If the phenotype of these primitive marrow cells changes from engraftable ste
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Koeniger, Tobias, Luisa Bell, Anika Mifka, et al. "Bone marrow-derived myeloid progenitors in the leptomeninges of adult mice." Stem Cells 39, no. 2 (2020): 227–39. http://dx.doi.org/10.1002/stem.3311.

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Abstract Although the bone marrow contains most hematopoietic activity during adulthood, hematopoietic stem and progenitor cells can be recovered from various extramedullary sites. Cells with hematopoietic progenitor properties have even been reported in the adult brain under steady-state conditions, but their nature and localization remain insufficiently defined. Here, we describe a heterogeneous population of myeloid progenitors in the leptomeninges of adult C57BL/6 mice. This cell pool included common myeloid, granulocyte/macrophage, and megakaryocyte/erythrocyte progenitors. Accordingly, i
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Dissertations / Theses on the topic "Stem progenitor cell"

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Prater, Michael David. "Progenitor and stem cell potential of mammary myoepithelial cells." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648364.

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Giraddi, Rajashekharagouda. "Cell cycle kinetics of mammary stem and progenitor cells." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.607789.

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Malandraki-Miller, Sophia. "Enhancing progenitor cells for cell therapy after myocardial infarction." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:205043f4-e3e0-4947-9afc-b43f1543e0bd.

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Based on data from the World Healthcare Organisation, cardiovascular diseases are the primary cause of disease-related death globally, with myocardial infarction (MI) being the most prevalent. If not treated effectively, MI can progress to heart failure (HF). With 70 million prescriptions for HF in 2014 and 515 people in the UK being hospitalised daily with MI, the British Heart Foundation calls for novel robust treatments. Even though cardiac stem cell (CSC) therapy for MI has been under investigation for more than a decade, there still has not been a consensus over the identity of the adult
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Dause, Tyler. "Investigating Neural Stem and Progenitor Cell Intracrine Signaling." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1555618643450352.

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Saleh, Lubaid. "Small molecule mediated targeting of haematopoietic stem/progenitor cell and leukaemic stem cell function." Thesis, Cardiff University, 2017. http://orca.cf.ac.uk/105172/.

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Haematopoietic stem cells (HSC) are a rare population of cells that have the ability to self-renew and differentiate giving rise to various blood lineages, thereby reconstituting the whole haematopoietic system. This is an essential characteristic, exploited in bone marrow transplantation therapy in response to myeloablative treatment. Due to their rarity, the lack of sufficient HSC numbers for transplantation has proved to be a major clinical issue. Separately, in the development of leukaemia, acquired mutations in HSCs give rise to malignant cells. These cells, like HSCs, have the ability to
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Behbahani, John. "The Role of MicroRNAs in Endothelial Progenitor Cell Function." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/35080.

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Cultures of peripheral blood mononuclear cells (MNCs) give rise to at least two different variants of endothelial progenitor cells (EPCs), early and late outgrowth EPCs. We investigated whether microRNAs in early and late EPCs could serve as markers of internal processes that can be exploited to distinguish cell identity and functional capacity. We hypothesized that as MNCs give rise to early and late EPCs, there is a gradual change in total microRNA profile, reflecting a total change in processes within the predominant cell population. Using a candidate microRNA array, early and late EPCs sho
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Kwee, Edward. "Quantitative Assays for Characterizing Stem and Progenitor Cell Populations." Case Western Reserve University School of Graduate Studies / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=case1474906437312739.

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Kollek, Matthias [Verfasser], and Miriam [Akademischer Betreuer] Erlacher. "Improvement of hematopoietic stem cell transplantations by transient apoptosis inhibition in donor stem and progenitor cells." Freiburg : Universität, 2016. http://d-nb.info/1136263462/34.

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Greenhowe, Jennifer. "Stem and progenitor cells in wound healing." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:87a9a7a1-b595-458a-913f-64497174f988.

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As more patients with large body surface area burns are surviving and requiring reconstructive surgery, there is a necessity for advances in the provision of bioengineered alternatives to autologous skin cover. The aims of this Thesis are to identify feasible source tissues of Endothelial Colony Forming Cells and Mesenchymal Stem/Stromal Cells for microvascular network formation in vitro with three-dimensional dermal substitute scaffolds. The working hypothesis is that pre-vascularised dermal scaffolds will result in better quality scarring when used with split thickness skin grafts. Human umb
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Hopp, I. "Novel synthetic biomaterials for kidney-derived progenitor/stem cell differentiation." Thesis, University of Liverpool, 2016. http://livrepository.liverpool.ac.uk/3004383/.

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End-stage kidney disease is increasing in prevalence and is associated with high levels of morbidity and mortality. At present, the only treatment options are dialysis or renal transplantation. However, dialysis is very costly and is associated with high levels of morbidity, whereas the problem with transplantation is that there is a shortage of organ donors. For these reasons, over recent years, there has been an increasing interest in developing novel therapies in the field of regenerative medicine including stem cell based therapies and tissue engineering. Stem cells could be used in a numb
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Books on the topic "Stem progenitor cell"

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American Association of Blood Banks., ed. Standards for hematopoietic progenitor cell services. 2nd ed. American Association of Blood Banks, 2000.

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Atala, Anthony. Progenitor and stem cell technologies and therapies. Woodhead Publishing, 2012.

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American Association of Blood Banks. Standards for hematopoietic progenitor cell and cellular product services. 3rd ed. American Association of Blood Banks, 2002.

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Co, Business Communications, ed. Stem cell and progenitor cell therapy: Current uses and future possibilities. Business Communications Co., 2002.

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Mendelson, Avital. Chondrogenesis of Stem/Progenitor Cells by Chemotaxis Using Novel Cell Homing Systems. [publisher not identified], 2012.

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Wartenberg, Hubert, Andreas Miething, and Kjeld Møllgård. The Origin of a New Progenitor Stem Cell Group in Human Development. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-02050-7.

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Reynolds, Brent A., and Loic P. Deleyrolle. Neural progenitor cells: Methods and protocols. Humana Press, 2013.

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American Association of Blood Banks. Progenitor Cell Standards Task Force., ed. Standards for hematopoietic progenitor cells. American Association of Blood Banks, 1996.

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Davidoff, Michail S., Ralf Middendorff, D. Müller, and Adolf F. Holstein. The Neuroendocrine Leydig Cells and their Stem Cell Progenitors, the Pericytes. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-00513-8.

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Arturo, Álvarez-Buylla, and García-Verdugo José Manuel, eds. Identification and characterization of neural progenitor cells in the adult mammalian brain. Springer, 2009.

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Book chapters on the topic "Stem progenitor cell"

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Kienstra, Kirsten A., and Karen K. Hirschi. "Vascular Progenitor Cell Mobilization." In Stem Cell Mobilization. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-943-3_13.

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Marlow, S. Darlene, and Myra House. "Hematopoietic Progenitor Cell Collection." In Stem Cell Mobilization. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-943-3_7.

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Hamilton, Eleanor S., and Edmund K. Waller. "Hematopoietic Progenitor Cell Apheresis Processing." In Stem Cell Mobilization. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-943-3_9.

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Brown, Melissa A., Cindy S. Cheng, and George A. Truskey. "Endothelial Progenitor Cells for Vascular Repair." In Stem Cell Engineering. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-11865-4_13.

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Fischer-Rasokat, Ulrich, and Stefanie Dimmeler. "Endothelial Progenitor Cells for Cardiac Regeneration." In Stem Cell Transplantation. Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/3527608745.ch12.

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Kolonin, Mikhail G. "Progenitor Cell Mobilization from Extramedullary Organs." In Stem Cell Mobilization. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-943-3_20.

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Gur-Cohen, Shiri, Kfir Lapid, and Tsvee Lapidot. "Quantifying Hematopoietic Stem and Progenitor Cell Mobilization." In Stem Cell Mobilization. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-943-3_2.

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Kronstein-Wiedemann, Romy, and Torsten Tonn. "Colony Formation: An Assay of Hematopoietic Progenitor Cells." In Stem Cell Mobilization. Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9574-5_3.

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Kienstra, Kirsten A., and Karen K. Hirschi. "Studying Vascular Progenitor Cells in a Neonatal Mouse Model." In Stem Cell Mobilization. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-943-3_19.

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Harting, Matthew T. "Basics of Stem and Progenitor Cells." In Progenitor Cell Therapy for Neurological Injury. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-965-9_1.

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Conference papers on the topic "Stem progenitor cell"

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Rajendiran, Shenbageshwaran, Francisco Galdos, Carissa Anne Lee, et al. "Modeling hiPSC-to-Early Cardiomyocyte Differentiation Process using Microsimulation and Markov Chain Models." In Foundations of Computer-Aided Process Design. PSE Press, 2024. http://dx.doi.org/10.69997/sct.152564.

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Cardiomyocytes (CMs), the contractile heart cells that can be derived from human induced pluripotent stem cells (hiPSCs). These hiPSC derived CMs can be used for cardiovascular disease drug testing and regeneration therapies, and they have therapeutic potential. Currently, hiPSC-CM differentiation cannot yet be controlled to yield specific heart cell subtypes consistently. Designing differentiation processes to consistently direct differentiation to specific heart cells is important to realize the full therapeutic potential of hiPSC-CMs. A model that accurately represents the dynamic changes i
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Zamani, Nurul Syahira Mohamad, Wan Mimi Diyana Wan Zaki, Aqilah Baseri Huddin, and Zariyantey Abdul Hamid. "Region of Interest Localisation of Hematopoietic Stem/Progenitor Cell Images." In 2022 IEEE 10th Conference on Systems, Process & Control (ICSPC). IEEE, 2022. http://dx.doi.org/10.1109/icspc55597.2022.10001743.

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Zhou, Robin, Andrew Hughes, Jane L. Liesveld, and Michael R. King. "Nanoparticle-Coated Microtubes for the Manipulation of Cancer Cells." In ASME 2010 8th International Conference on Nanochannels, Microchannels, and Minichannels collocated with 3rd Joint US-European Fluids Engineering Summer Meeting. ASMEDC, 2010. http://dx.doi.org/10.1115/fedsm-icnmm2010-30168.

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The development of novel methods for the isolation of primary stem and progenitor cells is important for the treatment of blood cancers, tissue engineering, and basic research in the biomedical sciences. Our lab has previously shown that microtubes coated with P-selectin protein can be used to capture and enrich hematopoietic stem and progenitor cells from a mixture of cells perfused through the tube at physiologically-relevant shear stresses[1][2], and that using a surface coating of colloidal silica nanoparticles (12 nm diameter, 30% by weight SiO2) increased cell capture and decreased rolli
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Santos, Sarah, Amber Heath, and Max Wicha. "Abstract 4215: Hypoxia regulates the breast cancer stem/progenitor cell population." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-4215.

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Asch, Adam S., Maria J. Ruiz-Echevarria, Jared Whelan, et al. "Abstract 4234: Translational regulation mediates hematopoietic progenitor cell generation in embryonic stem cell culture." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-4234.

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Joerger-Messerli, M., M. Spinelli, G. Thomi, et al. "Exosomes derived from Wharton's jelly stem cells switch neural progenitor cell fate to oligodendrogenesis." In 62. Kongress der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe – DGGG'18. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1671425.

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Dravis, Christopher, and Geoffrey M. Wahl. "Abstract IA10: Sox10 regulates stem/progenitor and mesenchymal cell states in mammary epithelial cells." In Abstracts: AACR Special Conference: Advances in Breast Cancer; October 17-20, 2015; Bellevue, WA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1557-3125.advbc15-ia10.

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Heo, Su-Jin, Nandan L. Nerurkar, Tristan P. Driscoll, and Robert L. Mauck. "Differentiation and Dynamic Tensile Loading Alter Nuclear Mechanics and Mechanoreception in Mesenchymal Stem Cells." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53432.

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Mesenchymal stem cells (MSCs) are a promising cell source for tissue engineering applications, given their ease of isolation and multi-potential differentiation capacity [1]. Passive and active mechanical signals can direct MSC lineage commitment [2], however, the subcellular machinery that translates physical cues to biologic response remains unclear. Direct deformation of the nucleus may influence differentiation by inducing mechanical reorganization of nuclear chromatin. Because the nuclei of differentiated cells are stiffer than progenitor cells [3], it is possible that such mechanoregulat
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Hartigan, Adam, John Westwick, Gabor Jarai, and Cory Hogaboam. "CCR7 Deficiency Enhances Hematopoietic Stem Cell And Myeloid Progenitor Cell Proliferation And Ameliorates Susceptibility To Invasive Pulmonary Aspergillosis Following Hematopoietic Stem Cell Transplantation." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5117.

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Erickson, Isaac E., Steven C. van Veen, Swarnali Sengupta, Sydney R. Kestle, Jason A. Burdick, and Robert L. Mauck. "Effects of Aging and TGF-Beta 3 on Chondrocyte and Mesenchymal Stem Cell Matrix Formation." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19517.

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Articular cartilage pathology is common in the aged population. Numerous studies have shown that aged chondrocytes (CHs) are inferior to juvenile CHs in their ability to proliferate and produce cartilage-specific extracellular matrix proteins, potentially limiting their use in tissue engineering applications for cartilage restoration [1,2]. Mesenchymal stem cells (MSCs) are an alternative cell type that can be expanded in vitro while maintaining their ability to differentiate into cell types comparable to articular chondrocytes. However, organismal aging also influences human MSC proliferation
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Reports on the topic "Stem progenitor cell"

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Lewis, Michael T. Unmasking Stem/Progenitor Cell Properties in Differentiated Epithelial Cells Using Short-term Transplantation. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada462432.

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Lewis, Michael T. Unmasking Stem/Progenitor Cell Properties in Differentiated Epithelial Cells Using Short-term Transplantation. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada482708.

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Lee, Adrian V. Novel Transgenic Mouse Model for Testing the Effect of Circulating IGF-I on Mammary Stem/Progenitor Cell Number and Tumorigenesis. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada494145.

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Lee, Adrian V. Novel Transgenic Mouse Model for Testing the Effect of Circulating IGF-I on Mammary Stem/Progenitor Cell Number and Tumorigenesis. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada474677.

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Shull, James D. Mammary Stem/Progenitor Cells and Cancer Susceptibility. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada567916.

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Paguirigan, Amy L. Development of Micro-Scale Assays of Mammary Stem and Progenitor Cells. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada487181.

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Sullivan, Genevieve M. The Regenerative Response of Endogenous Neural Stem/Progenitor Cells to Traumatic Brain Injury. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ad1012867.

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Liu, Can. MicroRNA Regulation of CD44+ Prostate Tumor Stem/Progenitor Cells and Prostate Cancer Development/Metastasis. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada580115.

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Halevy, Orna, Sandra Velleman, and Shlomo Yahav. Early post-hatch thermal stress effects on broiler muscle development and performance. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7597933.bard.

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In broilers, the immediate post-hatch handling period exposes chicks to cold or hot thermal stress, with potentially harmful consequences to product quantity and quality that could threaten poultry meat marketability as a healthy, low-fat food. This lower performance includes adverse effects on muscle growth and damage to muscle structure (e.g., less protein and more fat deposition). A leading candidate for mediating the effects of thermal stress on muscle growth and development is a unique group of skeletal muscle cells known as adult myoblasts (satellite cells). Satellite cells are multipote
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Steffenson, B. J., I. Mayrose, Gary J. Muehlbauer, and A. Sharon. ing and comparative sequence analysis of powdery mildew and leaf rust resistance gene complements in wild barley. United States-Israel Binational Agricultural Research and Development Fund, 2021. http://dx.doi.org/10.32747/2021.8134173.bard.

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Abstract:
Our overall, long-term goal is to exploit the genetic diversity present in cereal wild relatives for the development of cultivars with durable disease resistance. Our specific objectives for this proposal were to: 1) Utilize Association Genetics Resistance Gene Enrichment Sequencing (AgRenSeq) to identify and clone powdery mildew and leaf rust resistance gene complements in wild barley and 2) Conduct comparative sequence analyses of the cloned resistance genes to elucidate the basis of their specificity and evolution. The deployment of resistant cultivars is the most effective, economically ef
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