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Dissertations / Theses on the topic 'Tryptanthrin'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Yiu, Nai Sum. "Immunomodulatory effects of tryptanthrin on human bronchial epithelial cells." HKBU Institutional Repository, 2005. http://repository.hkbu.edu.hk/etd_ra/586.

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2

Chiu, I.-Fan, and 邱一帆. "I. The apoptotic activity of tryptanthrin derivatives in MCF7 cells II. Inhibition of TCDD-induced aryl hydrocarbon receptor translocation by tryptanthrin derivative DQ181." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/19816042560757980017.

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碩士<br>國立臺灣大學<br>藥學研究所<br>89<br>I. The apoptotic activity of tryptanthrin derivatives in MCF7 cells Tryptanthrin, indolo[2,1-b]quinazolin-6,12-dione, is a coplanar four-fused ring compound which contains N-phenyl-quinazoline skeleton similar to 2-phenyl-naphthalene. It was illustrated that compounds containing coplanar 2-phenyl-naphthalene skeleton exhibit different biological activites, while the bioactivities would be decreased or lost in unplanar structures. For example, batracylin, containing 2-phenyl-quinolone skeleton,inhibits the growth of carcinoma cell lines. In previous dat

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3

"Modulatory effects of tryptanthrin on the murine myeloid leukemia cells." 2008. http://library.cuhk.edu.hk/record=b5893599.

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Chan, Hoi Ling.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2008.<br>Includes bibliographical references (leaves 206-220).<br>Abstracts in English and Chinese.<br>ACKNOWLEDGEMENTS --- p.i<br>ABBREVIATIONS --- p.ii<br>ABSTRACT --- p.viii<br>撮要 --- p.xii<br>PUBLICATIONS --- p.xiv<br>TABLE OF CONTENTS --- p.xv<br>Chapter CHAPTER 1: --- GENERAL INTRODUCTION<br>Chapter 1.1 --- Hematopoiesis & Leukemia --- p.1<br>Chapter 1.1.1 --- An Overview on Hematopoiesis Development --- p.1<br>Chapter 1.1.2 --- Leukemia --- p.6<br>Chapter 1.1.2.1 --- General Symptoms of Leukemia --- p.7<br>C

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4

Lin, Yeh-Ssu, and 林曄思. "The Effect of Tryptanthrin in MCF-7 Breast Cancer Cells." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/08668569688413462113.

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碩士<br>國立臺灣大學<br>藥學研究所<br>97<br>Multidrug resistance (MDR), the resistance of tumor cells to anticancer agents, remains a major cause of treatment failure for cancer patients. MDR usually occurs with alteration of function and expression of some proteins and enzymes, for example P-gp (P-glycoprotein), MRP (multidrug resistance-related protein), topoisomerase and glutathione. Recently, the genes which show differential expressions in MCF-7/WT and its doxorubicin-resistant counterpart MCF-7/ADR include ER-α (estrogen receptor α), ER-β (estrogen receptor β), PR (progesterone receptor), VEGF（vascul

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5

Danz, Henning. "Untersuchungen zur antiinflammatorischen Wirkung und zur Analytik von Tryptanthrin in Isatis tinctoria L. /." 2001. http://www.gbv.de/dms/bs/toc/328938807.pdf.

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6

Chung, Chia-Hua, and 鍾佳華. "Effects of tryptanthrin on human hepatoma growth in vitro and in vivo." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/81248671303080476799.

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碩士<br>國立中興大學<br>食品暨應用生物科技學系所<br>99<br>Hepatocellular carcinoma is a common tumor in Asia and Africa area. Tryptanthrin is a weakly basic alkaloid and has been reported to have various functions, such as anti-microorganisms, anti-parasites, immunomodulatory, anti-inflammatory and anti-tumor activity in vitro. In this study, we examined the efficacy of tryptanthrin in suppression hepatoma growth and further investigated the mechanism by which tryptanthrin alter tumor cell growth. Tryptanthrin significantly inhibited human hepatoma cell proliferation in vitro. However, our data showed that tr

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7

曾詩韻. "The mechanism of tryptanthrin derivatives DQ150 and EY083 on inhibition of multidrug resistance." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/04382688704669895471.

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碩士<br>國立臺灣大學<br>藥學研究所<br>88<br>The resistance of tumor cells to anticancer agents remains a major cause of treatment failure for cancer patients. Agents as adjuvants to overcome MDR become a new trend in chemotherapy. We have evaluated the tryptanthrin derivatives DQ150 and EY083 for their reversing activity against P-glycoprotein-(P-gp) and MRP-mediated MDR in breast cancer cell lines MCF7, adriamycin-resistant MCF7/adr and etoposide-resistant MCF7/vp. Using MTT assay, 10-6M of DQ150 and EY083 had a 6-fold and 2-fold decrease in adriamycin IC50, respectively, in MCF7/adr. At mRNA l

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8

Yu, Sung-Tsai, and 尤松材. "The mechanism of tryptanthrin derivatives DQ150 and EY083 on inhibition of multidrug resistance." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/68672566595965765092.

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碩士<br>國立臺灣大學<br>藥學研究所<br>89<br>Chemotherapy is a common and effective treatment for tumors. However, the resistance of tumor cells to anticancer agents remains a major cause of treatment failure in cancer patients. Increased expression in tumor cells of plasma membrane proteins such as the P-glycoprotein (P-gp) or the multidrug resistance-associated protein 1 (MRP1) is often associated with such multidrug resistance (MDR) phenotype. P-glycoprotein and MRP1 both belong to membrane transport proteins of the large ATP-binding cassette (ABC) superfamily but share less than 20% amino acid identity.

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9

Chang, Hsin Ning, and 張心寧. "The anti-psoriatic effect and mechanism of indigo naturalis and its active component, tryptanthrin." Thesis, 2019. http://ndltd.ncl.edu.tw/cgi-bin/gs32/gsweb.cgi/login?o=dnclcdr&s=id=%22107CGU05521026%22.&searchmode=basic.

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10

Pinheiro, Daniela Ribeiro. "Synthesis, photophysical and electrochemical studies on tryptanthrin and indigo derivatives. Historic molecules with modern applications." Doctoral thesis, 2021. http://hdl.handle.net/10316/95405.

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Tese no âmbito do Doutoramento em Química, ramo de especialização em Fotoquímica, apresentada ao Departamento de Química da Faculdade de Ciências e Tecnologia da Universidade de Coimbra.<br>Indigo, an iconic molecule of colour, is included in the most ancient and important natural dyes used by mankind. The longevity as a colourant and unique properties of this compound are related with its high (photo)stability which is linked to a rapid proton transfer in the excited state (ESPT). In the past few years, indigo and its derivatives have gained renewed interest due to applications in several fie

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11

Chang, Ya-Lin, and 張雅琳. "Tryptanthrin, a natural product, exhibits novel antifungal activity and cell cycle arrest against Cryptococcus species." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/m87w7q.

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碩士<br>國立臺灣大學<br>植物病理與微生物學研究所<br>106<br>This study aims to identify bioactive compounds that exert novel antifungal activity alone or exhibit synergistic effect with an existing antifungal agent against human fungal pathogens Cryptococcus and Candida. We screened several compound libraries including natural products, agricultural fungicides and FDA-approved drugs in order to identify compounds that exert antifungal activity. Among selected compounds, tryptanthrin secreted from Nocardiopsis alba, an actinobacterium existed in the intestine of honeybee, was chosen for further characterization bec

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12

Wu, Hsing-Hung, and 吳信宏. "Studies on the Effects of Tryptanthrin and Its Derivative FV195 in Human Hepatoma Cell Line HuH7." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/46793140870304843982.

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13

Chen, Chia Sheng, and 陳佳聖. "The mechanism of tryptanthrin derivative DQ150 on inhibition of multidrug resistance in drug-resistant breast cancer lines." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/51937002512662796206.

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14

Oberthür, Christine [Verfasser]. "Indolische Sekundärmetabolite in Isatis tinctoria L. : Hautpenetration von Tryptanthrin und saisonale sowie prozessbedingte Veränderungen der Inhaltsstoffmuster / von Christine Oberthür." 2004. http://d-nb.info/97206639X/34.

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15

Surup, Frank. "Metagenom-Technologie zur Wirkstoffsuche sowie Untersuchungen der Iromycine aus Streptomyces sp." Doctoral thesis, 2007. http://hdl.handle.net/11858/00-1735-0000-0006-ACA7-B.

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