Academic literature on the topic 'WNT/planar cell polarity'

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Journal articles on the topic "WNT/planar cell polarity"

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Barrow, Jeffery R. "Wnt/planar cell polarity signaling." Organogenesis 7, no. 4 (2011): 260–66. http://dx.doi.org/10.4161/org.7.4.19049.

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Andre, Philipp, Qianyi Wang, Na Wang, et al. "The Wnt Coreceptor Ryk Regulates Wnt/Planar Cell Polarity by Modulating the Degradation of the Core Planar Cell Polarity Component Vangl2." Journal of Biological Chemistry 287, no. 53 (2012): 44518–25. http://dx.doi.org/10.1074/jbc.m112.414441.

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Funato, Yosuke, Tatsuo Michiue, Takeshi Terabayashi, et al. "Nucleoredoxin regulates the Wnt/planar cell polarity pathway inXenopus." Genes to Cells 13, no. 9 (2008): 965–75. http://dx.doi.org/10.1111/j.1365-2443.2008.01220.x.

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Yu, Joyce J. S., Aude Maugarny-Calès, Stéphane Pelletier, et al. "Frizzled-Dependent Planar Cell Polarity without Secreted Wnt Ligands." Developmental Cell 54, no. 5 (2020): 583–92. http://dx.doi.org/10.1016/j.devcel.2020.08.004.

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Kim, Sun K., Siwei Zhang, Michael E. Werner, et al. "CLAMP/Spef1 regulates planar cell polarity signaling and asymmetric microtubule accumulation in the Xenopus ciliated epithelia." Journal of Cell Biology 217, no. 5 (2018): 1633–41. http://dx.doi.org/10.1083/jcb.201706058.

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Most epithelial cells polarize along the axis of the tissue, a feature known as planar cell polarity (PCP). The initiation of PCP requires cell–cell signaling via the noncanonical Wnt/PCP pathway. Additionally, changes in the cytoskeleton both facilitate and reflect this polarity. We have identified CLAMP/Spef1 as a novel regulator of PCP signaling. In addition to decorating microtubules (MTs) and the ciliary rootlet, a pool of CLAMP localizes at the apical cell cortex. Depletion of CLAMP leads to the loss of PCP protein asymmetry, defects in cilia polarity, and defects in the angle of cell di
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Miyagi, Chiemi, Susumu Yamashita, Yusuke Ohba, Hisayoshi Yoshizaki, Michiyuki Matsuda, and Toshio Hirano. "STAT3 noncell-autonomously controls planar cell polarity during zebrafish convergence and extension." Journal of Cell Biology 166, no. 7 (2004): 975–81. http://dx.doi.org/10.1083/jcb.200403110.

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Zebrafish signal transducer and activator of transcription 3 (STAT3) controls the cell movements during gastrulation. Here, we show that noncell-autonomous activity of STAT3 signaling in gastrula organizer cells controls the polarity of neighboring cells through Dishevelled-RhoA signaling in the Wnt-planar cell polarity (Wnt-PCP) pathway. In STAT3-depleted embryos, although all the known molecules in the Wnt-PCP pathway were expressed normally, the RhoA activity in lateral mesendodermal cells was down-regulated, resulting in severe cell polarization defects in convergence and extension movemen
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Yang, Yingzi, and Marek Mlodzik. "Wnt-Frizzled/Planar Cell Polarity Signaling: Cellular Orientation by Facing the Wind (Wnt)." Annual Review of Cell and Developmental Biology 31, no. 1 (2015): 623–46. http://dx.doi.org/10.1146/annurev-cellbio-100814-125315.

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Goggolidou, Paraskevi. "Wnt and planar cell polarity signaling in cystic renal disease." Organogenesis 10, no. 1 (2013): 86–95. http://dx.doi.org/10.4161/org.26766.

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Daulat, Avais M., and Jean-Paul Borg. "Wnt/Planar Cell Polarity Signaling: New Opportunities for Cancer Treatment." Trends in Cancer 3, no. 2 (2017): 113–25. http://dx.doi.org/10.1016/j.trecan.2017.01.001.

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Ganner, Athina, Soeren Lienkamp, and Gerd Walz. "Planar cell polarity (PCP) and Wnt signaling in renal disease." Drug Discovery Today: Disease Mechanisms 10, no. 3-4 (2013): e159-e166. http://dx.doi.org/10.1016/j.ddmec.2013.12.001.

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Dissertations / Theses on the topic "WNT/planar cell polarity"

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Mei, Xue. "Wnt/planar cell polarity mechanisms in epilepsy and interactions with ciliopathy." Diss., University of Iowa, 2014. https://ir.uiowa.edu/etd/4695.

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The Wnt signaling network has critical roles in embryonic development and is implicated in human disease. One of the outputs of the Wnt network, called the planar cell polarity (PCP) pathway, regulates tissue polarity and directs cell migration. Core PCP components (Frizzled, Dishevelled, Prickle, Vangl, Celsr) localize asymmetrically in polarized cells and establish polarity across the tissue through protein interactions between adjacent cells. The core PCP component activate tissue-specific "effectors" which translate the signal into morphological changes. PCP is related to several disease c
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Watson, Julia Alice. "Investigating the role of Wnt/Planar cell polarity (PCP) in Neuromesodermal Progenitors (NMPs)." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31193.

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Neuromesodermal progenitors (NMPs) are bipotent progenitors, located at the caudal end of the embryo and are essential for axis formation. These stem cell-like progenitors possess the ability to self-renew and differentiate to both mesodermal and neural lineages, such as skeletal muscle and spinal cord derivatives. These progenitors arise at E8.5 and are localised in the caudal lateral epiblast (CLE), a posterior region of the embryo near the primitive streak. Later in development, they reside in the tail bud until cessation of axial elongation at E13.5. Throughout these stages NMPs are charac
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Schenkelaars, Quentin. "Origine et évolution des voies Wnt chez les métazoaires : étude comparée de diverses espèces d'éponges." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM4014.

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Les éponges (Porifera) sont l'une des premières lignées d'animaux à avoir émergé. De ce fait, elles sont considérées comme des espèces clés pour retracer l’origine et l'évolution des gènes et des voies de signalisation qui ont sous-tendu l'apparition de la pluricellularité chez les métazoaires. Entre autres, les voies Wnt ont été décrites comme des cascades génétiques essentielles du control de nombreux mécanismes cellulaires (prolifération, communication, adhésion, motilité, etc.) au cours du développement précoce des bilatériens et des cnidaires. C’est pourquoi, l'étude de ces voies, chez le
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Schäfer, Simon Thomas [Verfasser]. "ATP6AP2 is critically involved in adult hippocampal neurogenesis and reveals stage-specific functions for Wnt/ß-Catenin and Wnt/Planar Cell Polarity (PCP) signaling / Simon Thomas Schäfer." Greifswald : Universitätsbibliothek Greifswald, 2015. http://d-nb.info/1069389331/34.

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Wu, Mingfu. "A novel non-canonical WNT pathway regulates the asymmetric b cell division in Caenorhabditis elegans." Diss., Kansas State University, 2005. http://hdl.handle.net/2097/355.

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Doctor of Philosophy<br>Department of Biology<br>Michael A. Herman<br>The polarities of several cells that divide asymmetrically during C. elegans development are controlled by Wnt signaling. LIN-44/Wnt and LIN-17/Fz control the polarities of cells in the tail of developing C. elegans larvae, including the male-specific blast cell, B, which divides asymmetrically to generate a larger anterior daughter and a smaller posterior daughter. We determined that the canonical Wnt pathway components are not involved in the control of B cell polarity. However, POP-1/Tcf is involved and asymmetrically dis
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Barrott, Jared James. "Wnt5a Signaling Independently of the Planar Cell Polarity Pathway Resulting in Convergent Extension and Neural Tube Closure During Vertebrate Development." Diss., CLICK HERE for online access, 2008. http://contentdm.lib.byu.edu/ETD/image/etd2612.pdf.

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Nagy, I. I. (Irina I. ). "Wnt-11 signaling roles during heart and kidney development." Doctoral thesis, Oulun yliopisto, 2014. http://urn.fi/urn:isbn:9789526204666.

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Abstract Organogenesis involves precursor cells proliferation, differentiation along with their coordinated organization into precise multicellular arrangements by planar cell polarity (PCP) pathways. The beta-catenin independent/non-canonical type of Wnt-11 signaling has been known as a PCP modulator during development. In this thesis were analyzed the roles of Wnt-11 in heart and kidney development by using in vivo functional genomics technologies. We show that the Wnt-11 gene is important for murine ventricular myocardium development, since Wnt-11 deficiency in early cardiogenesis leads to
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Sun, Simon. "Planar Cell Polarity and Neurodevelopment." VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/3414.

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Planar cell polarity (PCP) is a developmental signaling mechanism that establishes a polarity within the plane of an epithelium. PCP has been shown to play a role in guiding numerous neurodevelopmental processes such as convergent extension, neuron migration, and axon pathfinding. Certain commissural neurons in the dorsal spinal cord make a series of guidance decisions en route to the brain: first, a ventral projection along the D-V axis, followed by a midline crossing, and after exiting the floorplate, a dorso-anterior turn along the A-P axis. Here, we provide in vivo evidence that the axons
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Schamberg, Sabine. "Modelling planar cell polarity in Drosophila melanogaster." Thesis, University of Nottingham, 2009. http://eprints.nottingham.ac.uk/12838/.

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During development, polarity is a common feature of many cell types. One example is the polarisation of whole fields of epithelial cells within the plane of the epithelium, a phenomenon called planar cell polarity (PCP). It is widespread in nature and plays important roles in development and physiology. Prominent examples include the epithelial cells of external structures of insects like the fruit fly Drosophila melanogaster, polarised tissue morphogenesis in vertebrates and sensory hair cells in the vertebrate ear. In this work we focus on the wing and the abdomen of Drosophila, where PCP be
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Harumoto, Toshiyuki. "Regulation of Noncentrosomal Microtubules in Planar Cell Polarity." 京都大学 (Kyoto University), 2011. http://hdl.handle.net/2433/142444.

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Books on the topic "WNT/planar cell polarity"

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Turksen, Kursad, ed. Planar Cell Polarity. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-61779-510-7.

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Zaffran, Stéphane. Cardiac growth II: Cardiomyocyte polarization. Edited by José Maria Pérez-Pomares, Robert G. Kelly, Maurice van den Hoff, et al. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757269.003.0010.

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During vertebrate embryogenesis, the planar cell polarity (PCP) signalling pathway is responsible for cell movements essential for convergent extension during gastrulation, neural tube closure, neural crest cell migration, and heart morphogenesis. In the heart, the non-canonical Wnt/PCP pathway regulates cell polarity, cell shape, and cell dynamics during formation of the cardiac crescent and deployment of second heart field cardiac progenitors to the poles of the heart tube. PCP signalling is also essential for the establishment of left–right patterning in the early embryo. This chapter revie
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Roskelley, Calvin. Planar Cell Polarity. Morgan & Claypool Life Science Publishers, 2012.

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Planar Cell Polarity During Development. Elsevier, 2012. http://dx.doi.org/10.1016/c2011-0-04515-5.

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Yang, Yingzi. Planar Cell Polarity During Development. Elsevier Science & Technology Books, 2012.

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Yang, Yingzi. Planar Cell Polarity During Development. Elsevier Science & Technology Books, 2012.

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Planar Cell Polarity Methods And Protocols. Humana Press, 2012.

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Turksen, Kursad. Planar Cell Polarity: Methods and Protocols. Humana Press, 2017.

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Planar Cell Polarity: Methods and Protocols. Humana Press, 2012.

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Wassarman, Paul, and Marek Mlodzik. Planar Cell Polarization During Development. Elsevier Science & Technology Books, 2005.

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Book chapters on the topic "WNT/planar cell polarity"

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Endo, Mitsuharu, Michiru Nishita, and Yasuhiro Minami. "Analysis of Wnt/Planar Cell Polarity Pathway in Cultured Cells." In Methods in Molecular Biology. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-61779-510-7_16.

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Kim, Gun-Hwa, Edmond Changkyun Park, and Jin-Kwan Han. "Wnt/Planar Cell Polarity Signaling in the Regulation of Convergent Extension Movements During Xenopus Gastrulation." In Methods in Molecular Biology. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-61779-510-7_7.

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Jessen, Jason R. "Analyzing Planar Cell Polarity During Zebrafish Gastrulation." In Methods in Molecular Biology. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-61779-510-7_6.

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Axelrod, Jeffrey D. "Mathematical Modeling of Planar Cell Polarity Signaling." In Springer Proceedings in Mathematics. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-20164-6_4.

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Li, Linxi, Haiqi Chen, Qingquan Lian, Ren-Shan Ge, and C. Yan Cheng. "Does planar cell polarity matter during spermatogenesis?" In Spermatogenesis. CRC Press, 2018. http://dx.doi.org/10.1201/9780429488634-17.

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Runkle, Kristin B., and Eric S. Witze. "Wnt-Dependent Control of Cell Polarity in Cultured Cells." In Methods in Molecular Biology. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6393-5_7.

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May-Simera, Helen, and Matthew W. Kelley. "Examining Planar Cell Polarity in the Mammalian Cochlea." In Methods in Molecular Biology. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-61779-510-7_13.

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Ossipova, Olga, Pamela Mancini, and Sergei Y. Sokol. "Imaging Planar Cell Polarity Proteins in Xenopus Neuroectoderm." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2035-9_10.

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LaMonica, Kristi, and Laura Grabel. "The Planar Cell Polarity Pathway and Parietal Endoderm Cell Migration." In Methods in Molecular Biology. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-61779-510-7_15.

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Cetera, Maureen, Rishabh Sharan, Gabriela Hayward-Lara, and Danelle Devenport. "Evaluating Planar Cell Polarity in the Developing Mouse Epidermis." In Methods in Molecular Biology. Springer US, 2024. http://dx.doi.org/10.1007/978-1-0716-3854-5_13.

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Conference papers on the topic "WNT/planar cell polarity"

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Borg, Jean-Paul. "Abstract 34: Identification of a phosphorylation cascade triggering Wnt/planar cell polarity signaling in breast cancer cells." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-34.

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Borg, Jean-Paul, Alexandra Walton, Eric Bailly, Sylvie Marchetto, and Stéphane Audebert. "Abstract 339: Identification of a novel isoform of WNT/planar cell polarity VANGL2 in breast cancer." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-339.

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Ho, M., K. R. Chaudhary, and D. J. Stewart. "Wnt/Planar Cell Polarity Pathway Signaling Between Endothelial Cell and Pericyte-Like Smooth Muscle Cells Enhance Vascular Repaving in an Acellular Lung Scaffold." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2554.

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Asad, Mohammad, Meng Kang Wong, Tuan Zea Tan, David Virshup, Jean Paul Thiery, and Ruby Yun-Ju Huang. "Abstract A30: Frizzled-7 (FZD7)-mediated non-canonical Wnt-Planar Cell Polarity (PCP) signalling pathway as a novel molecular driver for the C5/Proliferative/Stem-A molecular subtype of ovarian cancer." In Abstracts: AACR Special Conference: Advances in Ovarian Cancer Research: Exploiting Vulnerabilities; October 17-20, 2015; Orlando, FL. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1557-3265.ovca15-a30.

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Raffard, Robin, Keith Amonlirdviman, Jeffrey D. Axelrod, and Claire J. Tomlin. "Automatic Parameter Identification via the Adjoint Method, with Application to Understanding Planar Cell Polarity." In Proceedings of the 45th IEEE Conference on Decision and Control. IEEE, 2006. http://dx.doi.org/10.1109/cdc.2006.377697.

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Gao, Qian, Fei Liu, David Gilbert, Monika Heiner, and David Tree. "A multiscale approach to modelling planar cell polarity in Drosophila wing using hierarchically coloured Petri nets." In the 9th International Conference. ACM Press, 2011. http://dx.doi.org/10.1145/2037509.2037538.

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Lu, Zhiyi. "Navigating beyond the surface: unveiling the interplay of planar, apical-basal cell polarity, and cytoskeletal remodeling." In Third International Conference on Biological Engineering and Medical Science (ICBioMed2023), edited by Alan Wang. SPIE, 2024. http://dx.doi.org/10.1117/12.3013003.

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Roth, Doris, Remi Villenave, Anne Van Der Does, Pieter Hiemstra, and Janna Nawroth. "Late Breaking Abstract - High-content phenotypic profiling reveals that IL-13 impairs planar cell polarity and directional mucus clearance in human airway tissue." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.oa1898.

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