Academic literature on the topic 'Immune related diseases'

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Journal articles on the topic "Immune related diseases"

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Weksler, Marc E., Graham Pawelec, and Claudio Franceschi. "Immune therapy for age-related diseases." Trends in Immunology 30, no. 7 (2009): 344–50. http://dx.doi.org/10.1016/j.it.2009.03.011.

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Yang, Yaxu, Xue Han, Lijun Sun, Fangyu Shao, Yue Yin, and Weizhen Zhang. "ETS Transcription Factors in Immune Cells and Immune-Related Diseases." International Journal of Molecular Sciences 25, no. 18 (2024): 10004. http://dx.doi.org/10.3390/ijms251810004.

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The development, differentiation, and function of immune cells are precisely regulated by transcription factors. The E26 transformation-specific (ETS) transcription factor family is involved in various physiological and pathological processes by regulating cell proliferation, differentiation, and apoptosis. Emerging evidence has suggested that ETS family proteins are intimately involved in the development and function of immune cells. This review summarizes the role of the ETS family in immune cells and immune-related disorders. Seven transcription factors within the ETS family, including PU.1
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Singh, Dhirendra P., Prathyusha Bagam, Malaya K. Sahoo, and Sanjay Batra. "Immune-related gene polymorphisms in pulmonary diseases." Toxicology 383 (May 2017): 24–39. http://dx.doi.org/10.1016/j.tox.2017.03.020.

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Zeng, Jianrui, Zhaochen Ning, Yuzhong Wang, and Huabao Xiong. "Implications of CD39 in immune-related diseases." International Immunopharmacology 89 (December 2020): 107055. http://dx.doi.org/10.1016/j.intimp.2020.107055.

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Castiglione, F., S. Motta, F. Pappalardo, and M. Pennisi. "A Modeling Framework For Immune-related Diseases." Mathematical Modelling of Natural Phenomena 7, no. 3 (2012): 40–48. http://dx.doi.org/10.1051/mmnp/20127304.

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Candore, Giuseppina, Carmela Rita Balistreri, Giuseppina Colonna-Romano, et al. "Gender-Related Immune-Inflammatory Factors, Age-Related Diseases, and Longevity." Rejuvenation Research 13, no. 2-3 (2010): 292–97. http://dx.doi.org/10.1089/rej.2009.0942.

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de Freitas, Fábio Alessandro, Débora Levy, Cadiele Oliana Reichert, Edecio Cunha-Neto, Jorge Kalil, and Sérgio Paulo Bydlowski. "Effects of Oxysterols on Immune Cells and Related Diseases." Cells 11, no. 8 (2022): 1251. http://dx.doi.org/10.3390/cells11081251.

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Oxysterols are the products of cholesterol oxidation. They have a wide range of effects on several cells, organs, and systems in the body. Oxysterols also have an influence on the physiology of the immune system, from immune cell maturation and migration to innate and humoral immune responses. In this regard, oxysterols have been involved in several diseases that have an immune component, from autoimmune and neurodegenerative diseases to inflammatory diseases, atherosclerosis, and cancer. Here, we review data on the participation of oxysterols, mainly 25-hydroxycholesterol and 7α,25-dihydroxyc
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Souza, Felipe. "Neurological Diseases Associated to Immune Checkpoint Inhibitors." Neuroscience and Neurological Surgery 8, no. 6 (2021): 01–08. http://dx.doi.org/10.31579/2578-8868/177.

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The treatment for cancer has been more widespread and new therapies appear as alternatives in the area to contain the advance of the tumor, having with the immune mechanisms one of the main sources of research and study for a possible advance in the treatment. Checkpoint inhibitors (ICI) are monoclonal therapy, which act by blocking the PD-1, PD-L1 and CTLA-4 molecules, responsible for immune control. However, among the effects caused by therapy, the use of medications is associated with neurological diseases reported as an adverse effect. Neurological complications can affect both the central
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Yang, Dan, Shangxue Lei, Keran Pan, et al. "Application of photodynamic therapy in immune-related diseases." Photodiagnosis and Photodynamic Therapy 34 (June 2021): 102318. http://dx.doi.org/10.1016/j.pdpdt.2021.102318.

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Xu, Joella, Guannan Huang, and Tai Guo. "Developmental Bisphenol A Exposure Modulates Immune-Related Diseases." Toxics 4, no. 4 (2016): 23. http://dx.doi.org/10.3390/toxics4040023.

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Dissertations / Theses on the topic "Immune related diseases"

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Sotillo, Rodríguez Fernando. "Pathophysiology of immune-related complications in Lysinuric Protein Intolerance." Doctoral thesis, Universitat de Barcelona, 2018. http://hdl.handle.net/10803/463008.

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Lysinuric Protein Intolerance (LPI, MIM #222700) is a rare autosomic disease caused by mutations in SLC7A7 gene. Hallmarks of LPI are malabsorption and deficient renal reabsorption of cationic amino acids, which drives a deficit in the functioning of the urea cycle due to the reduction levels of arginine and ornithine in plasma. Nevertheless LPI patients also develop immune and hematologic complications such as anemia, pulmonary alveolar proteinosis or hemophagocytic lymphohistiocytosis. However the molecular mechanism(s) and/or the initiation events that trigger the development of LPI immune
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Onyebuchi, Iroezindu Michael. "Prevalence of HIV-related opportunistic diseases amongst HAART patients at the Federal Medical Centre in Owerri, Nigeria." Thesis, University of the Western Cape, 2012. http://hdl.handle.net/11394/5200.

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Magister Public Health - MPH<br>Background: The hallmark of HIV infection is immunosuppression which predisposes to unusual infections and malignancies generally known as opportunistic diseases (ODs). Globally, ODs are the major cause of morbidity and mortality in people living with HIV (PLHIV). Since the advent of Highly Active Antiretroviral Therapy (HAART), a significant decline in AIDS progression and ODs has been observed globally. However, most of the evidence suggesting sustained decline in AIDS progression and ODs has come from high-income settings with relatively less burden of ODs i
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Kitzmiller, Kathryn Jean. "Variation of Complement Factor H and Mannan Binding Lectin in Human Systemic and Vascular Immune-Mediated Diseases." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1261493418.

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Hardy, Olga T. "Role of the Monocyte/Macrophage Cell Lineage in Obesity-Related Insulin Resistance." eScholarship@UMMS, 2010. https://escholarship.umassmed.edu/gsbs_diss/464.

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Background Obesity is an important risk factor for resistance to insulin-mediated glucose disposal, and is a precursor of type 2 diabetes and other disorders. Objectives To identify molecular pathways in adipose tissue and inflammatory cells that may result in obesity-associated insulin resistance, we exploited the fact that not all obese individuals are prone to insulin resistance. Thus the degree of obesity as a variable was removed by studying obese subjects of similar body mass index (BMI) who are insulin-sensitive (IS) versus insulin-resistant (IR). Methods Combining gene expression profi
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Kühl, Thomas. "Pathogenic impact of immune-related cells in Batten disease." Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/pathogenic-impact-of-immunerelated-cells-in-batten-disease(ff86b71b-e859-4d91-a378-421eab71ae97).html.

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The neuronal ceroid lipofuscinoses (NCLs or Batten disease) are inherited neurodegenerative diseases of children. In all types of NCL glial activation, the innate immune response of the brain, precedes neurodegeneration. However, it is unclear whether adaptive immune responses are also involved in these diseases, or if they directly contribute to disease pathogenesis. Therefore, we examined the role of adaptive immune cells in mouse models of Infantile NCL (Ppt1-/- mice) and Juvenile NCL (Cln3-/- mice) by identifying, localising, and subsequently genetically removing immune components. Charact
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Parzych, Katarzyna. "The role of innate immune system receptors in smoking related disease." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/14371.

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Cigarette smoke induces inflammation, in part, by activation of Toll like receptor (TLR) 2 and TLR4. TLRs are present on most cells and recognize pathogen associated molecular patterns (PAMPs) and non-pathogenic molecules, known as danger associated molecular patterns (DAMPs). Activation of TLRs results in the propagation of a signalling pathway leading to the de novo synthesis of pro-inflammatory mediators that include CXCL8 and IL-1β. TLRs initiate inflammation and are involved in tissue repair processes in a number of diseases such as chronic obstructive pulmonary disease (COPD) and cancer.
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Coleman, Nicholas. "The local immune response to human papillomavirus-related disease in the female genital tract." Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319959.

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Hampson, Judith Anne. "Immune activation in alpha-1 antitrypsin deficiency related and usual chronic obstructive pulmonary disease." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8473/.

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A polyclonal increase in free light chains (FLCs) has been observed in a number of chronic inflammatory and autoimmune conditions and may be considered a biomarker of adaptive immune activation. The aim of this study was to examine whether FLCs could be a useful clinical biomarker in alpha-1 antitrypsin deficiency (A1ATD) and chronic obstructive pulmonary disease (COPD). Combined (\(\kappa\) & \(\lambda\)) FLCs (cFLCs) were measured in patients with AlATD and usual COPD in the stable state and assessed for association with clinical phenotype, disease severity, bacterial colonisation and mortal
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Mooney, John. "Molecular and cellular aspects of the humoral immune response in periodontal disease and other related conditions." Thesis, University of Glasgow, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321510.

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Bogner, Simon Sebastian [Verfasser], та Markus [Akademischer Betreuer] Glatzel. "Immune activation in Aβ-related angiitis (ABRA) and a cell model of E280A presenilin-mutated Familial Alzheimer's Disease / Simon Sebastian Bogner. Betreuer: Markus Glatzel". Hamburg : Staats- und Universitätsbibliothek Hamburg, 2014. http://d-nb.info/1059859823/34.

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Books on the topic "Immune related diseases"

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National Cancer Institute (U.S.), ed. Understanding cancer and related topics: Understanding gene testing. National Cancer Institute, 2011.

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Colloque, des "Cent gardes" (2nd 1987 Marnes-la-Coquette France). Retroviruses of human A.I.D.S. and related animal diseases: 2e collogue des "cent gardes", 28-30 octobre 1987, Marnes-la-Coquette/Paris, France. Pasteur vaccins, 1988.

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1929-, Newcombe David S., Rose Noel R, and Bloom John C, eds. Clinical immunotoxicology. Raven Press, 1992.

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L, Petrakis Peter, American Medical Society on Alcoholism and Other Drug Dependencies., National Council on Alcoholism, and AIDS and Chemical Dependency Forum (1986 : San Francisco, Calif.), eds. Acquired Immune Deficiency Syndrome and chemical dependency: Report of symposium. U.S. Dept. of Health and Human Services, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Alcohol Abuse and Alcoholism, 1987.

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Okolelova, Tamara, Syergyey YEngashyev, and Ivan Yegorov. Poultry farming: current questions and answers. Publishing Center RIOR, 2020. http://dx.doi.org/10.29039/02023-4.

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In the book in the form of questions and answers considerable attention is paid to data on the needs of all types of poultry in nutritional, mineral and biologically active substances, taking into account age of poultry. The characteristic of the main feed products is given, and the rational norms for including them in mixed feed for poultry are indicated. The role of vitamins, macro- and microelements, enzyme preparations, probiotics, prebiotics, antibiotics, organic acids, antioxidants, emulsifiers and other sources of biologically active substances in poultry nutrition is shown. Both nutrit
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Peter, Bridge T., Mirsky Allan F, and Goodwin Frederick K. 1936-, eds. Psychological, neuropsychiatric, and substance abuse aspects of AIDS. Raven Press, 1988.

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1931-, Friedman Herman, and Symposium on AIDS, Drugs of Abuse, and the Neuroimmune Axis (3rd : 1995 : San Diego, Calif.), eds. AIDS, drugs of abuse, and the neuroimmune axis. Plenum Press, 1996.

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Barbouche, Mohamed-Ridha, and Brian Stephen Eley, eds. Immune-Related Non-Communicable Diseases in Africa. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88974-419-0.

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Lee, Kyung-Yil, Hiromichi Hamada, and Miika Kaleva Arvonen, eds. Infection-Related Immune-Mediated Diseases and Microbiota. Frontiers Media SA, 2020. http://dx.doi.org/10.3389/978-2-88963-744-7.

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Maghazachi, Azzam A., ed. Immunomodulatory Effects of Drugs for Treatment of Immune-Related Diseases. Frontiers Media SA, 2017. http://dx.doi.org/10.3389/978-2-88945-288-0.

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Book chapters on the topic "Immune related diseases"

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Kemp, W. M. "Parasite Immune Escape Mechanisms." In Parasitic and Related Diseases. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-5027-9_3.

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Jin, Min, and Yanyun Zhang. "Autophagy and Immune-Related Diseases." In Autophagy: Biology and Diseases. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-4272-5_27.

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Giacomo, Quattrocchio, Barreca Antonella, and Dario Roccatello. "IgG4-Related Disease." In Rare Diseases of the Immune System. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-60855-1_5.

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Tan, Peng, Youqiong Ye, Jingrong Mao, and Lian He. "Autophagy and Immune-Related Diseases." In Advances in Experimental Medicine and Biology. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-15-0606-2_10.

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Paronetto, F. "Ethanol and the Immune System." In Alcohol Related Diseases in Gastroenterology. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70048-4_15.

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Pétursson, G. "Maedi-Visna. Etiology and Immune Response." In Maedi-Visna and Related Diseases. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4613-1613-8_4.

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Roccatello, Dario, Antonella Barreca, Savino Sciascia, et al. "Cryoglobulinemia and Emerging Related Disorders." In Rare Diseases of the Immune System. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-60855-1_4.

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Cappelli, Laura C., and Clifton O. Bingham. "Immune-Related Adverse Events with Immune Checkpoint Inhibitors: Arthritis." In Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-56824-5_4.

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Wright, Fred W. "Inflammatory, Hypersensitivity and Immune Lung Diseases, including Parasitic Diseases." In Radiology of the Chest and Related Conditions. CRC Press, 2022. http://dx.doi.org/10.4324/9780429272967-19.

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Balaji, Aanika, Bairavi Shankar, and Jarushka Naidoo. "Non-Rheumatic Immune-Related Adverse Events." In Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-56824-5_10.

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Conference papers on the topic "Immune related diseases"

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Kawaoka, Tatsuya, Ryota Sakayama, Kousaku Ohta, and Masatoshi Funabashi. "Open Complex Systems Approach Utilizing ICT to Address Immune-Related Diseases in Aging Society." In 11th International Conference on Information and Communication Technologies for Ageing Well and e-Health. SCITEPRESS - Science and Technology Publications, 2025. https://doi.org/10.5220/0013359900003938.

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Gee, A. P. "Hematopoietic Stem Cell Engineering: The Magic Bullet of the Next Millenium?" In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-1317.

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Abstract Hematopoietic stem cell [HSC] therapy has its origins as hematological rescue following marrow ablative high-dose therapy for refractory cancers and myelodysplastic syndromes. In its simplest form, bone marrow is collected from a tissue-matched related normal donor and intravenously infused into the patient who has usually received high-dose chemo/radiotherapy for his or her disease. The stem cells migrate to the marrow spaces, where they multiply and differentiate to restore blood cell-forming activity and immune defenses in the recipient Restrictions in the availability of tissue-ma
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Lin, Erica M., Rachel Lim, Tricia Li, Martin Weinstock, Abrar Qureshi, and Eunyoung Cho. "Abstract 844: Immune-related diseases and risk of skin cancer." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-844.

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Fenton, KA, M. Van Ghelue, and OP Rekvig. "OP0009 Sle-related t cell autoimmunity to histones and nucleosomes is an inherent property of the normal immune system." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.1234.

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Eryilmaz, Mahmut Kaan, Cihan Kuzudisli, and Burcu Bakir Gungor. "İmmün Bağlantılı Hastalıklarda Aktif Alt Ağ Araması ile Ortak Hastalık Oluşum Mekanizmalarının Tespiti : Identification of Shared Pathways Among Immune Related Diseases Utilizing Active Subnetworks." In 2020 5th International Conference on Computer Science and Engineering (UBMK). IEEE, 2020. http://dx.doi.org/10.1109/ubmk50275.2020.9219492.

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Wagner, Filip. "Očkování z pohledu práva." In Naděje právní vědy 2022. University of West Bohemia, Czech Republic, 2023. http://dx.doi.org/10.24132/zcu.nadeje.2022.798-807.

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Vaccination is one of the basic ways to prevent infectious diseases and their related consequences. The basic purpose of vaccination is to induce an immune response of the organism as a reaction to the encounter with the relevant antigen and possibly other components of the vaccine. In addition to the individual protection of the individual who has undergone vaccination, from the point of view of protection against serious diseases transmitted from person to person, it is desirable to achieve collective protection, which can be achieved through a sufficiently high proportion of vaccinated and
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Araldi, Bianca Barbosa, Victor Hugo Gomes, Bruno Ludvig Vieira, et al. "Effects of multiple sclerosis in pregnant and post-birth: particularities of the disease activity." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.704.

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Introduction: Demyelinating diseases are a heterogeneous group of neurological diseases related to autoimmunity whose representative is Multiple Sclerosis (MS). It is characterized by an immune-mediated demyelination of the central nervous system, with a typical outbreak and remission clinic. During pregnancy, a reduction in disease activity was noted due to immunomodulatory effects, and an increase in outbreaks in the puerperium. Thus, our goal is to demonstrate the relationship between pregnancy and MS. Methods: This is a systematic bibliographic review based on searching the SCIELO, PUBMED
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Andrade, Dariana Rodrigues, Letícia Mendes de Lima, Luis Henrique Goes Hamati Rosa, and Edvaldo Cardoso. "Brain-gut-microbiota axis in motor disorders." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.401.

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Introduction: There seems to be a strong relationship and influence on the brain-gut- microbiota axis in the control and prevention of several diseases, including degenerative diseases that are related to motor disorders. Objectives: To analyze the relationship between movement disorders and the intestinal microbiota. Methods: Integrative review performed at PUBMED, using the descriptors Movement disorder and intestinal microbiota, in the last five years and having as inclusion criteria complete texts in English. Results: The literature suggests that the intestinal microbiota regulates the act
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Dias, Alice Estevo, Bruna Helena Sciarini, Juliana Aparecida Rhein Telles, Ibis Ariana, Carlos Monteiro, and Talita Dias da Silva. "A case study on dysarthria present in coexisting autoimmune diseases." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.655.

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Introduction: Autoimmune diseases are characterized by immune dysfunction, autoantibody production and chronic inflammation. The aim is to describe dysarthria in a case that combines autoimmune diseases. Case report: This study reports the case of a 43-year-old woman with complaints of speech difficulties and a diagnosis of dysarthria due to Multiple Sclerosis, Sjögren’s Syndrome, Raynaud’s Phenomenon, Systemic Lupus Erythematosus and Hashimoto’s Thyroiditis. Assessments were performed using the GRBASI scale, Praat software and Voice Related Quality of Life Protocol for six years consecutive.
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Pascu, Corina, Viorel Herman, Sara Gatto, and Luminita Costinar. "RETROSPECTIVE STUDY OF WEST NILE VIRUS IN ITALY." In 10th SWS International Scientific Conferences on SOCIAL SCIENCES - ISCSS 2023. SGEM WORLD SCIENCE, 2023. http://dx.doi.org/10.35603/sws.iscss.2023/sv07.31.

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The infectious diseases are mainly the consequence of the existence of the microbialworld, essential for life on our planet. Microbes need a superior animal to multiply andspread to survive. The pathogens are therefore the biological agents responsible for theonset of the disease condition in the host organism. The infectious disease appears to bethe consequence of the interaction between pathogens and specific defense systems,immune response, and nonspecific (inflammation) of the host.West Nile virus (WNV) belongs to the family Flaviviridae and implies the West Nilefever (WNF) a vector-borne
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Reports on the topic "Immune related diseases"

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Avni, Adi, and Gitta L. Coaker. Proteomic investigation of a tomato receptor like protein recognizing fungal pathogens. United States Department of Agriculture, 2015. http://dx.doi.org/10.32747/2015.7600030.bard.

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Maximizing food production with minimal negative effects on the environment remains a long-term challenge for sustainable food production. Microbial pathogens cause devastating diseases, minimizing crop losses by controlling plant diseases can contribute significantly to this goal. All plants possess an innate immune system that is activated after recognition of microbial-derived molecules. The fungal protein Eix induces defense responses in tomato and tobacco. Plants recognize Eix through a leucine-rich-repeat receptor- like-protein (LRR-RLP) termed LeEix. Despite the knowledge obtained from
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Chejanovsky, Nor, and Bruce A. Webb. Potentiation of Pest Control by Insect Immunosuppression. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7592113.bard.

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The restricted host range of many baculoviruses, highly pathogenic to Lepidoptera and non-pathogenic to mammals, limits their use to single or few closely related Lepidopteran species and is an obstacle to extending their implementation for pest control. The insect immune response is a major determinant of the ability of an insect pathogen to efficiently multiply and propagate. We have developed an original model system to study the Lepidopteran antiviral immune response based on Spodoptera littoralis resistance to AcMNPV (Autographa californica multiple nucleopolyhedrovirus) infection and the
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Kotler, Moshe, Larry Hanson, and Shane Burgess. Replication Defective Cyprinid Herpes Virus-3 (CyHV-3) as a Combined Prophylactic Vaccine in Carps. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7697104.bard.

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Aquacultured koi and common carp fish (Cyprinus carpio) are intensively bred as ornamental and food fish in many countries worldwide. Hatcheries of carp and koi have recently suffered massive financial damages due to two viral diseases caused by the Cyprinid herpesvirus-3 (CyHV-3), previously designated as Carp Interstitial Nephritis and Gill Necrosis Virus (CNGV) and Koi herpesvirus (KHV), and by the Spring Viremia of Carp Virus (SVCV). CyHV-3 is a large dsDNA virus, which is infectious mostly to koi and common carp, while SVCV is a rhabdovirus with a relatively broad host range. Both viruses
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Yogev, David, Ricardo Rosenbusch, Sharon Levisohn, and Eitan Rapoport. Molecular Pathogenesis of Mycoplasma bovis and Mycoplasma agalactiae and its Application in Diagnosis and Control. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7573073.bard.

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Mycoplasma bovis and M. agalactiae are two phylogenetically related mycoplasmas which cause economically significant diseases in their respective bovine or small ruminant hosts. These organisms cause persistent asymptomatic infections that can result in severe outbreaks upon introduction of carrier animals into susceptible herds. Little is known about the mechanisms underlying mycoplasma-host interaction, variation in virulence, or of the factors enabling avoidance of the host immune system. In recent years it has become apparent that the ability of pathogenic microorganisms to rapidly alter s
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wang, hesong, chunyang song, wenzhao deng, xiaohan zhao, and wenbin shen. Evaluation of Neoadjuvant Immune Combined Therapy and Traditional Neoadjuvant Therapy for Resectable Esophageal Cancer: A Systematic Review and Single-arm and Network Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.12.0060.

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Review question / Objective: Population: Patients with histologically-confirmed resectable esophageal carcinoma; Intervention: Neoadjuvant immunotherapy combined with chemotherapy or neoadjuvant immunotherapy combined with chemoradiotherapy followed by surgery; Control: Neoadjuvant chemotherapy or neoadjuvant chemoradiotherapy followed by surgery; Outcomes: Treatment related adverse events, r0 resection rate, pathological complete response, major pathological response, objective response rate, disease control rate, postoperative complications, postoperative mortality, 1/2/3/5year overall survi
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Bain, Luchuo Engelbert, and Darja Dobermann. Malaria, HIV and TB in the Democratic Republic of the Congo: Epidemiology, Disease Control Challenges and Interventions. Institute of Development Studies (IDS), 2022. http://dx.doi.org/10.19088/k4d.2022.034.

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Malaria, human immune deficiency virus (HIV) and tuberculosis (TB) are leading causes of death and public health threat to millions in Democratic Republic of Congo (DRC). The DRC is the second most malaria affected sub-Saharan African country after Nigeria, with malaria being the leading cause of death in children under 5 years (Lechthaler et al., 2019). The HIV prevalence in the country in the adult population stands at 1%, with extensive variations by region (UNAIDS, 2021c). The DRC is considered a high burden country for TB and HIV infection (Linguissi et al., 2017). This rapid review empha
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He, Dan, Hongmei Wu, Yujie Han, Min Liu, and Mao Lu. A meta-analysis of topical antifungal drugs to treat atopic dermatitis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.12.0062.

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Review question / Objective: Various bacteria and fungi colonize the skin surface of patients with AD. The colonized fungi mainly include Malassezia, non-Malassezia yeasts, and molds. Among them, Malassezia occupies 63%~86% of the fungal colonization community on the skin surface of AD patients. Although the relationship between the level of Malassezia on the skin surface and disease severity remains controversial, many studies have shown that the level of serum anti-Malassezia-specific immunoglobulin E (IgE) antibodies in AD patients is related to the disease severity, especially in patients
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Knibb, Rebecca, Lily Hawkins, and Dan Rigby. Food Sensitive Study: Wave Two Survey. Food Standards Agency, 2022. http://dx.doi.org/10.46756/sci.fsa.nyx192.

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Food hypersensitivities (FH) include food allergy, food intolerance and coeliac disease. Food allergy and coeliac disease involve an immune mediated reaction to certain foods; food intolerance is caused by a non-immune mediated reaction (such as an enzymatic or pharmacological effect). Each of these FHs result in unpleasant symptoms if the food is eaten in sufficient quantity, with food allergic reactions sometimes resulting in life-threatening symptoms. Management of FH by an individual or members of their family therefore involves constant vigilance and risk assessment to determine if a food
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Xu, Junjie, Jiaye Liu, Xinquan Lan, Moxin Song, Liangyuan Zhang, and Jiaqi Zhang. Efficacy of the third dose of COVID-19 vaccine: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.11.0114.

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Review question / Objective: To investigate the immune response and related clinical outcomes of healthy adults who received coronavirus vaccine booster compared with those who did not receive the vaccine booster. Condition being studied: The COVID-19 pandemic, which has spread since 2019, has created a huge disease and economic burden on the world. A large number of clinical trials have verified the effectiveness of COVID-19 vaccine. Previous studies have found that the serum conversion rate and antibody level of those vaccinated after the first two doses of COVID-19 vaccine continue to decre
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Zhao, Zepeng, Fengyuan Zhang, and Yijin Li. The Relationship Between Il-1 RN intron 2 (VNTR) rs2234663 Gene Polymorphism and The Progression of Periodontitis: A systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.3.0100.

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Review question / Objective: The aim of this systematic review and meta-analysis of case-control studies is to find out the association of IL-1 RN intron 2 (VNTR) rs2234663 Gene Polymorphism and the occurrence and progression of periodontitis(including chronic periodontitis, aggressive periodontitis and early-onset periodontitis). Condition being studied: Periodontitis is one of the most common ailments affecting the teeth, leading to the destruction of the supporting and surrounding tooth structure. Periodontitis is originally a disease originating from the gingival tissue which if left untre
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