Relevant bibliographies by topics / Opioid drug addiction

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Opioid drug addiction'

Author: Grafiati
Published: 28 May 2022
Last updated: 30 July 2025

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Journal articles on the topic "Opioid drug addiction"

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Yang, Zhaolin. "Opioid-Induced Neuroplasticity: Insights from Animal Models." Communications in Humanities Research 40, no. 1 (2024): 137–43. http://dx.doi.org/10.54254/2753-7064/40/20242277.

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Synaptic plasticity is defined as the modification of the transmission of synapses. It has been proven to be strongly associated with learning. Thus, drug-evoked synaptic plasticity in brain reward circuits can establish persistent learning of addictive drugs, reflecting the neural basis underlying addiction. The mesolimbic dopamine pathway has been widely indicated to be strongly associated with opioid use disorder (OUD) and other drug addictions. The paper focuses on discussing the drug-evoked neural plasticity underlying two important stages called intoxication and withdrawal which are crit
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Praveen, Kumar Mishra* Swati Khare Dr. Jitendra Banweer. "Impact of Opioid Toxicity on Workplace Productivity." International Journal of Scientific Research and Technology 2, no. 5 (2025): 401–7. https://doi.org/10.5281/zenodo.15426428.

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Opioids are derived from opiates they include also synthetic and semi-synthetic drugs. Opioids have both recreational and medical uses. Opioid abuse is a worldwide problem with numerous and increasing mortality due to overdose. Opioids act on the opiate receptors as a potent mu receptor agonist resulting in a complex intracellular signals leading to dopamine release causing euphoria, and pain signal blocking. In cases of overdose, there is an excessive effect on respiratory center, resulting in respiratory depression and eventually death. Opioids can lower the perception of pain and in some ca
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Evans, Christopher J., and Catherine M. Cahill. "Neurobiology of opioid dependence in creating addiction vulnerability." F1000Research 5 (July 19, 2016): 1748. http://dx.doi.org/10.12688/f1000research.8369.1.

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Opioid drugs are potent modulators of many physiological and psychological processes. When given acutely, they can elicit the signature responses of euphoria and analgesia that societies have coveted for centuries. Repeated, or chronic, use of opioids induces adaptive or allostatic changes that modify neuronal circuitry and create an altered normality — the “drug-dependent” state. This state, at least that exhibited by those maintained continuously on long-acting opioid drugs such as methadone or buprenorphine, is generally indistinguishable from the drug-naïve state for most overt behaviors.
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Collen, Mark. "Opioid Contracts and Random Drug Testing for People with Chronic Pain — Think Twice." Journal of Law, Medicine & Ethics 37, no. 4 (2009): 841–45. http://dx.doi.org/10.1111/j.1748-720x.2009.00455.x.

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It is common for physicians who prescribe opioids for chronic pain to have their patients sign an opioid contract (OC) in order to receive opioid therapy. A vast majority of these contracts contain a stipulation requiring patients to submit to random drug testing (RDT) which screens for both licit and illicit drugs. Physicians who prescribe opioids may be concerned about prosecution and disciplinary actions; medication abuse and misuse; and addiction. Steven Passik et al. write, “…physicians still fear the risk of abuse or addiction as well as the potential legal consequences of their prescrib
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Bechara, Antoine, Kent C. Berridge, Warren K. Bickel, Jose A. Morón, Sidney B. Williams, and Jeffrey S. Stein. "A Neurobehavioral Approach to Addiction: Implications for the Opioid Epidemic and the Psychology of Addiction." Psychological Science in the Public Interest 20, no. 2 (2019): 96–127. http://dx.doi.org/10.1177/1529100619860513.

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Two major questions about addictive behaviors need to be explained by any worthwhile neurobiological theory. First, why do people seek drugs in the first place? Second, why do some people who use drugs seem to eventually become unable to resist drug temptation and so become “addicted”? We will review the theories of addiction that address negative-reinforcement views of drug use (i.e., taking opioids to alleviate distress or withdrawal), positive-reinforcement views (i.e., taking drugs for euphoria), habit views (i.e., growth of automatic drug-use routines), incentive-sensitization views (i.e.
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Le Merrer, Julie, Jérôme A. J. Becker, Katia Befort, and Brigitte L. Kieffer. "Reward Processing by the Opioid System in the Brain." Physiological Reviews 89, no. 4 (2009): 1379–412. http://dx.doi.org/10.1152/physrev.00005.2009.

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The opioid system consists of three receptors, mu, delta, and kappa, which are activated by endogenous opioid peptides processed from three protein precursors, proopiomelanocortin, proenkephalin, and prodynorphin. Opioid receptors are recruited in response to natural rewarding stimuli and drugs of abuse, and both endogenous opioids and their receptors are modified as addiction develops. Mechanisms whereby aberrant activation and modifications of the opioid system contribute to drug craving and relapse remain to be clarified. This review summarizes our present knowledge on brain sites where the
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Yang, Junzhi, Bianca Reilly, Thomas Davis, and Patrick Ronaldson. "Modulation of Opioid Transport at the Blood-Brain Barrier by Altered ATP-Binding Cassette (ABC) Transporter Expression and Activity." Pharmaceutics 10, no. 4 (2018): 192. http://dx.doi.org/10.3390/pharmaceutics10040192.

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Opioids are highly effective analgesics that have a serious potential for adverse drug reactions and for development of addiction and tolerance. Since the use of opioids has escalated in recent years, it is increasingly important to understand biological mechanisms that can increase the probability of opioid-associated adverse events occurring in patient populations. This is emphasized by the current opioid epidemic in the United States where opioid analgesics are frequently abused and misused. It has been established that the effectiveness of opioids is maximized when these drugs readily acce
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Hieu, Dang Minh, Benjamin Gray, Dang Minh Tuan, and Benjamin P. Colman. "Facing drug addiction: Vietnam’s struggle with opioids." Drug Science, Policy and Law 7 (January 2021): 205032452110349. http://dx.doi.org/10.1177/20503245211034934.

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Drug addiction is a historical issue in Vietnam. Although Vietnam has a long history as a producer of opium poppies and crossroads for the illicit drug trade, it is now has some of the most stringent drug laws in the world. Vietnam has shown some success in reducing the production, trade, and transportation of narcotics. There has also been a shift in the attitudes of lawmakers and government authorities toward viewing drug abuse as a health problem rather than a social vice. Educating and encouraging citizens to collaboratively reduce drug use has also proven effective. However, despite these
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Yan, Y., and E. Gutkevich. "Differences in addictive beliefs in people with psychostimulant addiction and in opioid addicts." European Psychiatry 65, S1 (2022): S818. http://dx.doi.org/10.1192/j.eurpsy.2022.2117.

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Introduction Today, a number of researchers consider the problem of addictive behavior as one of the most global problems for Kazakhstan and Russia. Some scientists consider CBT to be the most effective way to work with addictions. In our country there are no scientific works devoted to the study of addictive beliefs, so we decided to conduct such a study Objectives The Objective of the study was to identify the characteristic addictive beliefs of drug addicts with different type of addiction: opioids and synthetic cathinones (designer drugs called “salts”, “bath salts”) Methods Questionnaire
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Rezaeifar, Alireza, and Fatemeh Dahmardeh. "The Effect of OPRM1 rs648893 Gene Polymorphism on Opioid Addiction in an Iranian population in Zabol: A Case-Control Study." International Journal of Basic Science in Medicine 4, no. 4 (2019): 143–47. http://dx.doi.org/10.34172/ijbsm.2019.04.

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Introduction: Opioid addiction (OA) is a neurologically life-threatening challenge associated with socioeconomic and health concerns for individuals and society. The addictive drugs trigger neuromodulators and neurotransmitters through the opioid receptors and corresponding endogenous peptide ligands. In addition, drug addiction is reportedly related to the mu-opioid receptor (OPRM1) encoding gene and its variants. According to the role of the rs648893 polymorphism of the OPRM1 gene in numerous disorders, it has been suggested as a candidate associated with drug addiction. The present case-con
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Dissertations / Theses on the topic "Opioid drug addiction"

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Sandweiss, Alexander Jordan, and Alexander Jordan Sandweiss. "The Role of Substance P in Opioid Induced Reward." Diss., The University of Arizona, 2016. http://hdl.handle.net/10150/621568.

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Chronic pain affects approximately 100 million Americans. Opioids are the mainstay therapy for the treatment of chronic pain. While physicians and patients alike are apprehensive about using opioids due to their side effects including respiratory depression and addiction, 259 million opioid prescriptions were written in 2012. Although opioids are the most efficacious available analgesics, they increase both positive and negative reinforcement, ultimately leading to addiction. The pro-nociceptive neurotransmitter, Substance P (SP) and its corresponding receptor (NK₁R), are not only found on pai
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Henderson, Heather D. "“I am More Than my Addiction”: Perceptions of Stigma and Access to Care in Acute Opioid Crisis." Scholar Commons, 2018. http://scholarcommons.usf.edu/etd/7167.

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The goal of this research is to analyze the stigmatization of opioid addiction within the framework of emergency care from an ethnographic perspective. Interviews with those who have been swept up in the current opioid epidemic indicate that stigma, or a shame or dishonor, and socioeconomic insecurity emerge often as common themes in their emergency care experiences. In many cases, socioeconomic insecurity most intensely translates into a lack of access to healthcare and emergency rooms across the country often function as primary care for uninsured populations. The central field site selected
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Jefferies, Stella Kiah. "Medication-Assisted Therapy Interventions and Prescription Opioid Misuse." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/6223.

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Opioid drug misuse and dependence are a social and public health problem in the United States. Prescription opioid abuse and misuse have been associated with substantial morbidity and mortality rates as well as social and economic costs. The purpose of this project was to provide a systematic review of literature on the effectiveness of medication-assisted therapy interventions in addressing the problem of prescription opioid misuse in health care settings. The systematic review was completed through a literature search conducted across five electronic databases. The review was guided by the h
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Spivack, Stephanie. "The Care of Hospitalized Intravenous Drug Users in 2019." Master's thesis, Temple University Libraries, 2019. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/553776.

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Urban Bioethics<br>M.A.<br>People who inject drugs, particularly opioids, are a growing population, especially in North Philadelphia. This population is at high risk for medical complications that require hospitalization. While hospitalized, this population poses unique challenges to the healthcare system, including high costs and readmission rates, as well as stress and burnout among providers and staff. These patients are at high risk of discharges against medical advice because of complicated social factors as well as inadequate recognition of pain and withdrawal. As the opioid epidemic evo
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Salwan, Aaron J., Nicholas E. Hagemeier, and Sam Harirforoosh. "Abuse-Deterrent Opioid Formulations: A Key Ingredient in the Recipe to Prevent Opioid Disasters?" Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/2763.

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The US Food and Drug Administration (FDA) is encouraging the innovation of long-acting opioid formulations that are manipulation-resistant. The purpose of this commentary is to assess the benefits and limitations of abuse-deterrent opioid formulations (ADFs) and discuss their role in mitigating the current opioid epidemic. ADFs have been created with chemical properties that make it difficult for people who non-medically use prescription drugs to crush and dissolve opioid tablets, as well as by combining opioids with antagonists such as naloxone or naltrexone, which are released only when the
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Pierce, Matthias. "Opioid use in England and Wales : mortality, crime and the effectiveness of treatment." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/opioid-use-in-england-and-wales-mortality-crime-and-the-effectiveness-of-treatment(4e7de6f9-2060-4e85-9f8c-c832be8c989f).html.

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Background: The UK has a high prevalence of opioid use; although this population is ageing. The use of opioids is associated with excess mortality and offending and so remains a priority for public health and criminal justice policy. Aims: There are two broad aims for this thesis: firstly, to quantify excess mortality and offending associated with opioid use, and secondly, to assess the effectiveness of drug treatment at reducing these harms. Methods: Cohorts were extracted from the Drug Data Warehouse (DDW); a collection of case-linked drug treatment and criminal justice datasets, linked to m
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Pack, Robert P. "Opioid Use Disorder." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/1335.

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Mullins, Jonathan David. "A Comparative Study of Recovery Ecosystems for Opioid Use Disorder in Portugal and Appalachia." Digital Commons @ East Tennessee State University, 2021. https://dc.etsu.edu/honors/620.

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A comparison of the structure and effectiveness of recovery ecosystems for opioid use disorder in Portugal and Appalachia, with a focus on identifying areas for improvement within the Appalachian region.
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Pack, Robert P. "Opioid Use in Tennessee: Lessons Learned." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/1342.

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Hagemeier, Nicholas E., J. Nile Barnes, and Kasey Strey. "The Prescription Opioid Epidemic: How it Happened and Solutions." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/1414.

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Rates of prescription drug misuse in Texas are alarmingly high. One in five Texas high school students have taken prescription drugs without a doctor’s prescription. In 2015, Texas had the second highest total healthcare costs from opioid abuse in the nation ($1.96 billion), and Texas is home to four of the top 25 cities in the U.S. for opioid abuse. Meanwhile, only one in three prescribers is using the statewide Prescription Drug Monitoring Program (PDMP), leading to a massive loss of data. There is substantial need for increased infrastructure and prevention measures in Texas, especially rel
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Books on the topic "Opioid drug addiction"

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C, Strain Eric, and Stitzer Maxine L, eds. Methadone treatment for opioid dependence. Johns Hopkins University Press, 1999.

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2

S, Rapaka Rao, Sorer Heinz, and National Institute on Drug Abuse., eds. Discovery of novel opioid medications. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Institute on Drug Abuse, 1995.

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Kauffman, Janice Fay. Matching treatment to patient needs in opioid substitution therapy. U.S. Dept. of Health and Human Services, Public Health Service, Substance Abuse and Mental Health Services Administration, Center for Substance Abuse Treatment, 1995.

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Kauffman, Janice Fay. Matching treatment to patient needs in opioid substitution therapy. U.S. Dept. of Health and Human Services, Public Health Service, Substance Abuse and Mental Health Services Administration, Center for Substance Abuse Treatment, 1995.

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S, Rapaka Rao, Sorer Heinz, and National Institute on Drug Abuse., eds. Discovery of novel opioid medications. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Institute on Drug Abuse, 1995.

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C, Strain Eric, and Stitzer Maxine L, eds. The treatment of opioid dependence. Johns Hopkins University Press, 2005.

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Elwood, William N. Leaning on syrup: The misuse of opioid cough syrup in Houston. Texas Commission on Alcohol and Drug Abuse, 1999.

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McNicholas, Laura. Clinical guidelines for the use of buprenorphine in the treatment of opioid addiction. U.S. Dept. of Health and Human Services, Substance Abuse and Mental Health Services Administration, Center for Substance Abuse Treatment, 2004.

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S, Harris Louis, and National Institute on Drug Abuse. Office of Science., eds. Problems of drug dependence, 1986: Proceedings of the 48th Annual Scientific Meeting, the Committee on Problems of Drug Dependence, Inc. U.S. Dept. of Health and Human Services, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Drug Abuse, Office of Science, 1987.

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National Institute on Drug Abuse, ed. Addiction careers: Summary of studies based on the DARP 12-year followup. U.S. Dept. of Health and Human Services, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Drug Abuse, 1986.

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Book chapters on the topic "Opioid drug addiction"

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Schiller, Peter W. "Opioid Peptide-Derived Analgesics." In Drug Addiction. Springer New York, 2008. http://dx.doi.org/10.1007/978-0-387-76678-2_22.

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Kane, Brian E., Bengt Svensson, and David M. Ferguson. "Molecular Recognition of Opioid Receptor Ligands." In Drug Addiction. Springer New York, 2008. http://dx.doi.org/10.1007/978-0-387-76678-2_34.

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Schmidhammer, H. "Opioid Receptors." In Drug Addiction and AIDS. Springer Vienna, 1991. http://dx.doi.org/10.1007/978-3-7091-9173-6_17.

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Ananthan, Subramaniam. "Opioid Ligands with Mixed μ/δ Opioid Receptor Interactions: An Emerging Approach to Novel Analgesics." In Drug Addiction. Springer New York, 2008. http://dx.doi.org/10.1007/978-0-387-76678-2_23.

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Raehal, Kirsten M., and Laura M. Bohn. "Mu Opioid Receptor Regulation and Opiate Responsiveness." In Drug Addiction. Springer New York, 2008. http://dx.doi.org/10.1007/978-0-387-76678-2_36.

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Metcalf, Matthew D., and Andrew Coop. "Kappa Opioid Antagonists: Past Successes and Future Prospects." In Drug Addiction. Springer New York, 2008. http://dx.doi.org/10.1007/978-0-387-76678-2_25.

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Witt, Ken A., and Thomas P. Davis. "CNS Drug Delivery: Opioid Peptides and the Blood-Brain Barrier." In Drug Addiction. Springer New York, 2008. http://dx.doi.org/10.1007/978-0-387-76678-2_30.

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Gupta, Achla, Fabien M. Décaillot, and Lakshmi A. Devi. "Targeting Opioid Receptor Heterodimers: Strategies for Screening and Drug Development." In Drug Addiction. Springer New York, 2008. http://dx.doi.org/10.1007/978-0-387-76678-2_32.

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Pogozheva, Irina D., Magdalena J. Przydzial, and Henry I. Mosberg. "Homology Modeling of Opioid Receptor-Ligand Complexes Using Experimental Constraints." In Drug Addiction. Springer New York, 2008. http://dx.doi.org/10.1007/978-0-387-76678-2_33.

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Shippenberg, Toni S., and Vladimir I. Chefer. "Opioid Modulation of Psychomotor Stimulant Effects." In Molecular Biology of Drug Addiction. Humana Press, 2003. https://doi.org/10.1007/978-1-59259-343-9_7.

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Conference papers on the topic "Opioid drug addiction"

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Süer, Kaya, Omid Mirzaei, Kadir Yelmi, and Aslı Aykaç. "The Relationship Between Drug Addiction and Significant Infectious Diseases." In Panel on "Effective Drug Control Strategies in Northern Cyprus: Challenges and Opportunities in 2024". Emanate Publishing House Ltd., 2024. http://dx.doi.org/10.70020/ehass.2024.7.4.

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Substance addiction can be explained as individuals’ unrestrained desire to consume a substance although such consumption harms their mental, physical, and social lives. Addicts are exposed to stigmatization and discrimination, which limits their ability to get the help they need. In 2021, one in every 17 people between the ages of 15 and 64 was found to be using drugs, which is a 23% increase compared to 10 years ago. In addition to overdose, hepatitis C virus (HCV) and human immunodeficiency virus (HIV) are the leading causes of deaths related to drug use. Research on drug use by gender show
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Astaf'eva, E. A., T. A. Tolochko, and A. A. Timofeeva. "THE EFFECT OF POLYMORPHISM OF THE MTHFR C677T GENE ON THE MORPHOFUNCTIONAL STATE OF LYMPHOCYTES DURING DRUG INTOXICATION." In I International Congress “The Latest Achievements of Medicine, Healthcare, and Health-Saving Technologies”. Kemerovo State University, 2023. http://dx.doi.org/10.21603/-i-ic-8.

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The prevalence of opioid dependence among the able-bodied population is an important&#x0D; medical and social problem. Methylenetetrahydrofolate reductase (MTHFR) plays a key role in the&#x0D; metabolism of narcotic drugs. A decrease in the enzyme activity in polymorphic variants of the&#x0D; gene encoding it is associated with a decrease in the immunity of opioid addiction patients.
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Bratosin, Ioan alexandru, Ionelbujorel Pavaloiu, Andrei Vasilateanu, Nicolae Goga, Diana Gavajuc, and George Dragoi. "VIRTUAL REALITY THERAPY FOR PAIN." In eLSE 2020. University Publishing House, 2020. http://dx.doi.org/10.12753/2066-026x-20-193.

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Pain is the unpleasant condition raised as a normal response of the body to injury and illness. In the case of Chronic Pain Syndrome, this can ailment can continue even after the cause that provoked it has disappeared. The classical painkiller medicines (like paracetamol, non-steroidal anti-inflammatory drugs and opioids) are used as therapy, but they raise problems of overdose, adverse side-effects and addiction. Virtual Reality Therapy (VRT) is showing promise as a possible drug-free substitute for pain management. The VRT lets patients to navigate through Virtual Reality environments and to
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Reports on the topic "Opioid drug addiction"

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Mark, Tami L., William N. Dowd, and Carol L. Council. Tracking the Quality of Addiction Treatment Over Time and Across States: Using the Federal Government’s “Signs” of Higher Quality. RTI Press, 2020. http://dx.doi.org/10.3768/rtipress.2020.rr.0040.2007.

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The objective of this study was to track trends in the signs of higher-quality addiction treatment as defined by the National Institute on Drug Abuse, the National Institute on Alcohol Abuse and Addiction, and the Substance Abuse and Mental Health Services Administration. We analyzed the National Survey of Substance Abuse Treatment Services from 2007 through 2017 to determine the percent of facilities having the characteristics of higher quality. We analyzed the percent by state and over time. • We found improvements between 2007 and 2017 on most measures, but performance on several measures r
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Conteh, Abu. SSHAP West Africa Hub: Addressing the Kush Epidemic in Sierra Leone. Institute of Development Studies, 2024. http://dx.doi.org/10.19088/sshap.2024.060.

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Sierra Leone has seen a sharp rise in the use of ‘kush’ – a relatively new drug formed through mixing several constituent drugs, including opioids, which is proving highly addictive and is having serious negative health and social consequences. In April 2024, the government declared a public health emergency resulting from high levels of kush use, with security services launching crackdowns.1 Limited data on kush use presents challenges to understanding the scale of the problem. The lack of evidence has hampered the government’s response to the kush crisis. This has contributed to a misunderst
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Brown, Candace, Chudney Williams, Ryan Stephens, Jacqueline Sharp, Bobby Bellflower, and Martinus Zeeman. Medicated-Assisted Treatment and 12-Step Programs: Evaluating the Referral Process. University of Tennessee Health Science Center, 2021. http://dx.doi.org/10.21007/con.dnp.2021.0013.

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Purpose/Background Overdose deaths in the U.S. from opioids have dramatically increased since the COVID-19 pandemic. Although medicated-assisted treatment (MAT) programs are widely available for sufferers of opiate addiction, many drop out of treatment prematurely. Twelve-step programs are considered a valuable part of treatment, but few studies have examined the effect of combining these approaches. We aimed to compare abstinence rates among patients receiving MAT who were referred to 12-step programs to those only receiving MAT. Methods In this prospective study, a cohort of participants fro
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