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Dissertations / Theses on the topic 'Phytochemicals'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Singh, Rachna. "Interaction of phytochemicals with dairy ingredients." Thesis, University of Auckland, 2011. http://hdl.handle.net/2292/9025.

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The primary objective of this thesis is to evaluate the interaction of milk protein/polyphenolic complexes and phospholipid membranes. Milk-proteins (casein, whey protein concentrate- WPC or milk protein concentrate-MPC) and polyphenols were either introduced when the liposomes were fabricated or mixed with preformed liposomes. A third combination was also used where polyphenol was incorporated into liposomes and milk proteins were mixed. The challenge of incorporating plant polyphenols into dairy foods is to retain their antioxidant activities. These polyphenols inhibit lipid oxidation in cel

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2

Nandakumar, Vijayalakshmi. "DNA methylation patterns in the ultraviolet radiation-exposed skin and tumors chemopreventive role of phytochemicals /." Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2009r/nandakumar.pdf.

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3

Gana, Kalliopi. "The role of phytochemicals in preventative medicine." Thesis, Liverpool John Moores University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403279.

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4

Girlus, Elena Valeria. "Protective activity of phytochemicals from natural extracts." Master's thesis, Instituto de Tecnologia Química e Biológica António Xavier. Universidade Nova de Lisboa, 2016. http://hdl.handle.net/10362/43593.

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The rise in the incidence of neurodegenerative diseases leads to an increased demand for the development of alternative therapeutic strategies. Phytochemicals have proved beneficial effects for human health, exerting protective roles towards several diseases including neurodegenerative disorders. Thus, the search for new bioactivities is a field in constant growth. The beet and fruits belonging to Opuntia spp. are rich in betalains and phenolic compounds, which confer several benefits to human health such as regulators of antioxidant and anti-inflammatory responses as well as potential protect

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5

Dean, Chalkley Tracey Shelly. "The effects of soy isoflavones on risk factors for coronary heart disease." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269628.

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6

Miller, Lori B. "Phytochemicals as a motivational tool to change fruit, vegetable and whole grain consumption." Online version, 2002. http://www.uwstout.edu/lib/thesis/2002/2002millerl.pdf.

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7

Foley, Sarah. "Photochemical and photobiological studies of photosensitisers and phytochemicals." Thesis, Keele University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.389604.

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8

Vaz, Marcela Tatiana Barros. "Unraveling phytochemicals with potential therapeutic application for neurodegeneration." Master's thesis, Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica António Xavier, 2017. http://hdl.handle.net/10362/69938.

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"Epidemiological data suggest that phytochemicals may prevent and even reverse specific pathological processes underlying neurodegenerative diseases. A (poly)phenol-enriched fraction from leaves of Corema album was previously reported to modulate central events related to α-Synuclein expression and aggregation as well as oxidative stress in eukaryotic models of Parkinson’s disease. In order to identify the potentially bioactive compound, this extract was subjected to a bioguided fractionation, leading to the identification of CAL_X.(...)"<br>N/A

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9

Nakamura, Yoshimasa. "CANCER CHEMOPREVENTION BY FOOD PHYTOCHEMICALS REGULATING INFLAMMATORY LEUKOCYTES." Kyoto University, 1998. http://hdl.handle.net/2433/157118.

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本文データは平成22年度国立国会図書館の学位論文(博士)のデジタル化実施により作成された画像ファイルを基にpdf変換したものである<br>Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第7409号<br>農博第993号<br>新制||農||762(附属図書館)<br>学位論文||H10||N3155(農学部図書室)<br>UT51-98-G338<br>京都大学大学院農学研究科食品工学専攻<br>(主査)教授大東肇, 教授佐々木隆造, 教授吉川正明<br>学位規則第4条第1項該当

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10

Gebreselassie, Etsehiwot Yohannes. "Composition and Stability of Phytochemicals during Food Processing." Thesis, North Dakota State University, 2015. https://hdl.handle.net/10365/27469.

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Dietary phytochemicals are thought to reduce the incidence of chronic degenerative diseases. The concentration of these phytochemicals has been extensively studied, but less is known about their stability during food processing. The objective of this study was to determine the stability of lignans and other phytochemicals during the vinification and brewing processes. The amount of secoisolariciresinol diglucoside (SDG), gallic acid, caffeic acid, coumaric acid, chlorogenic acid, and ferulic acid increased up to 45 % during the vinification process; however, the amount of folic acid remained u

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11

Watson, Anthony. "The psychopharmacological effects of blackcurrant phytochemicals in humans." Thesis, Northumbria University, 2014. http://nrl.northumbria.ac.uk/34139/.

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Self-medication of plant based foods and food extracts which have ostensible therapeutic benefits has considerably increased within non-clinical populations over the last two decades. The overarching reason for this rise in consumption is to improve health and cognitive performance. One such group of foods are flavonoid-rich berry fruits. In the literature, there has been a recent rise in evidence showing that the consumption of flavonoid-rich berries can modulate aspects of behaviour, especially memory, in animal models and in aged humans. Physiological parameters such as blood-flow and gluco

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12

Harjo, Benny. "Process development in the manufacture of natural products /." View abstract or full-text, 2006. http://library.ust.hk/cgi/db/thesis.pl?CENG%202006%20HARJO.

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13

DeÌpeint, Flore. "Dietary phytochemicals and their effect on colon cell proliferation." Thesis, University of East Anglia, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399768.

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14

Soon, Grace Ing. "The bone anabolic potential of dietary lysine and phytochemicals." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613967.

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15

DE, LUCIA DANIELA. "Phytochemicals: Design, Synthesis, Biological Evaluation and Novel Characterisation Methods." Doctoral thesis, Università degli studi di Ferrara, 2015. http://hdl.handle.net/11392/2487876.

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16

Chu, Qingjun. "S-allylcysteine (SAC) and S-allylmercaptocysteine (SAMC), water soluble garlic derivatives, suppress growth and invasion of androgen-independent prostate cancer, under in vitro and in vivo conditions." View the Table of Contents & Abstract, 2006. http://sunzi.lib.hku.hk/hkuto/record/B36749540.

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17

Howard, Edward William. "The potential clinical applications of garlic-derived S-allylmercaptocysteine in the treatment of hormone refractory prostate cancer." View the Table of Contents & Abstract, 2007. http://sunzi.lib.hku.hk/hkuto/record/B38165156.

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18

Satterfield, Mary Bolling. "Enhanced detection and structural characterization of phytochemicals with metal complexation using electrospray ionization mass spectrometry /." Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3008435.

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19

Goggans, Mallory. "Elucidating Tomato Steroidal Glycoalkaloid Metabolism and Effects of Consumption onthe Gut Microbiome in a Pig Model." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1594824484770731.

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20

Chan, Nicholas. "Separation and purification of high value phytochemicals from plant biomass." Thesis, University of Ottawa (Canada), 2008. http://hdl.handle.net/10393/27962.

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Phytochemicals are the individual chemicals from which plants are made and are alternatively referred to as natural products, which have been used since ancient times as drugs. In modern times, natural products are still used as drugs; however, more importantly they are used as a source of new leads into new bioactive compounds. Paclitaxel and betulinic acid, in particular are prized for their characteristics as anti-cancer compounds among other traits. The following work examines the extraction of paclitaxel from Taxus canadensis on a pilot scale set-up using Dynamic Pressurized Liquid Extra

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21

Watanabe, Hiroko. "Studies on gut bacterial metabolisms of food-derived bioactive phytochemicals." Doctoral thesis, Kyoto University, 2020. http://hdl.handle.net/2433/253330.

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京都大学<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第22494号<br>農博第2398号<br>新制||農||1076(附属図書館)<br>学位論文||R2||N5274(農学部図書室)<br>京都大学大学院農学研究科応用生命科学専攻<br>(主査)教授小川順, 教授栗原達夫, 教授加納健司<br>学位規則第4条第1項該当<br>Doctor of Agricultural Science<br>Kyoto University<br>DFAM

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22

Sekiguchi, Hirotaka. "Suppressive Effects of Food Phytochemicals on Adhesion of Helicobacter pylori." Kyoto University, 2010. http://hdl.handle.net/2433/120492.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第15449号<br>農博第1834号<br>新制||農||982(附属図書館)<br>学位論文||H22||N4548(農学部図書室)<br>27927<br>京都大学大学院農学研究科食品生物科学専攻<br>(主査)教授入江一浩, 教授井上國世, 教授河田照雄<br>学位規則第4条第1項該当

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23

Rodriguez, Montes de Oca Gustavo Alejandro. "Evaluation of dietary phytochemicals on sex differentiation and growth in Nile tilapia (Oreochromis niloticus)." Columbus, Ohio : Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1133358425.

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24

Deakin, Sherine Jane. "Antioxidant effects of phytochemicals in conditions of oxidative stress : impact on endothelial cell survival and function." Thesis, University of Aberdeen, 2010. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=165549.

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Two dietary polyphenols, delphinidin and resveratrol, were selected for this study; delphinidin, an anthocyanin flavonoid, was found to elicit cardioprotective properties from a pilot study and resveratrol, a stilbene flavonoid, one of the most studied of the polyphenols and was chosen as a worthy comparator. <i>In vitro</i> studies using cultured endothelial cells exposed to a variety of reactive oxygen species (ROS) were used to determine if delphinidin and resveratrol could protect these cells from oxidative damage. It was found that physiological concentrations of delphinidin protected the

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25

Harbottle, Jennifer Amy. "In vitro idenfitication and characterisation of phytochemical inducers of the cell stress response." Thesis, University of Aberdeen, 2017. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=236073.

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26

Zainol, Murizal. "Assessment of phytochemicals in preventing oxidatively damaged DNA in bladder cancer." Thesis, University of Leicester, 2011. http://hdl.handle.net/2381/10158.

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Oxidatively damaged DNA is thought to be important in both the initiation and development of bladder carcinoma. Phytochemical compounds are thought to promote optimal health, partly via their antioxidant effects in protecting cellular components against damaging free radicals. The objective of this study is to assess the effect of a standardised bilberry extract, mirtoselect, on the level of endogenous and induced oxidatively damaged DNA in bladder cancer cells, as assessed by the Comet assay. The Comet assay, also known as single-cell gel electrophoresis, represents a simple method for measur

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27

Brown, Emma Marie. "Anticancer effects of soft fruit phytochemicals in models of colon cancer." Thesis, University of Ulster, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551561.

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Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. Due to its pattern of increased incidence and mortality rates in Western countries, lifestyle factors, particularly diet, have been implicated in the aetiology of this disease. Recently, interest in the consumption of polyphenols, especially abundant in berries, has received a great deal of attention due to the putative anticancer activity of these compounds. In vivo, polyphenols undergo digestive conditions post consumption that alters the structure and possibly the function of these compounds. The focus of this study was

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28

Wake, George. "Cholinergic phytochemicals from medicinal herbs : potential sources of novel dementia treatments." Thesis, University of Newcastle Upon Tyne, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366551.

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29

Adam, Virginie Sarah. "Prostate cancer targeting using replication-selective adenoviruses in combination with phytochemicals." Thesis, Queen Mary, University of London, 2009. http://qmro.qmul.ac.uk/xmlui/handle/123456789/204.

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Oncolytic adenoviral mutants have demonstrated good safety profiles but, despite some encouraging clinical results, efficacy as a single agent was limited. Combinations with conventional chemo- or radiotherapy significantly enhanced the anti-tumour effect. We investigated the possibility of enhancing prostate cancer (PCa) cell killing using adenovirus type 5 (Ad5) with phytochemicals. Phytochemicals are chemopreventive and can modulate intracellular signalling pathways, including the mitogen-activated protein kinase (MAPK) pathway which regulates the expression of the coxsackie-adenovirus rece

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30

Alkandari, Fatemah Ahmad Hassan. "Characterisation of Escherichia coli in poultry and their interaction with phytochemicals." Thesis, University of Reading, 2017. http://centaur.reading.ac.uk/76613/.

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Avian pathogenic Escherichia coli (APEC) and commensal E. coli are often found in the intestinal tract of poultry. APEC can cause several types of disease manifesting at various developmental stages in the life cycle of poultry. The goals of this study were to investigate the relationship between APEC and commensal E. coli, and to elucidate whether specific dietary components such as plant extracts (thymol and carvacrol) may be implemented to control APEC. Genotypic and phenotypic diversities were estimated in 200 E. coli isolates from poultry of which 100 were from healthy turkey, 35 from hea

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31

Chen, Feifei. "Gold nanoparticle mediated membrane permeabilization of phytochemicals into breast cancer cells." Thesis, University of Missouri - Columbia, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10180873.

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<p> Breast cancer is one of the most common cancers in women with a very high incident rate, especially for those women who are between 40-60 years old. Most drugs are large or non-polar macromolecules, which cannot get into cancer cells autonomously, so a method that can deliver those drugs is very important. Optoporation method has been facilitated with gold nanoparticles, which are bound to breast cancer cells, and then absorb the optical energy to improve the membrane permeabilization. Long-term dietary consumption of fruits and vegetables high in β-carotene and other phytochemicals h

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32

Cichon, Morgan Julienne. "Investigating the Role of Tomato Phytochemicals through Targeted and Untargeted Metabolomics." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1449226913.

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33

Johnsson, Pernilla. "Bioactive phytochemicals in flaxseed : with particular emphasis on the secoisolariciresinol oligomer /." Uppsala : Department of Food Science, Swedish University of Agricultural Sciences, 2009. http://epsilon.slu.se/200957.pdf.

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34

Almoyad, Muhammad. "Synergism from combination of targeted therapy and phytochemicals in colorectal cancer." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/18161.

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Colorectal cancer is the second most common cancer in women and third in men, accounting for 9.7 % of all cancers incidence. Oxaliplatin is a platinum-based anticancer drug used typically in combination with folinic acid and 5-fluorouracil for treatment against colorectal cancer. However, numerous side effects such as nausea and vomiting, GI toxicity, anaemia, immunodeficiency, ototoxicity, nephrotoxicity, and neurotoxicity are associated with its use. These can be decreased by lowering dose of oxaliplatin. Phytochemicals that can act as antioxidants have been used by people in treatment again

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35

Al, Onazi Fahad Nasser. "Platinum drugs given in combination with phytochemicals to enhance platinum action." Thesis, The University of Sydney, 2017. http://hdl.handle.net/2123/18971.

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This study focused on the sequenced combinations of platinum drugs cisplatin and oxaliplatin and four phytochemicals celastrol, guggulsterone, garcinol and ellagic acid administered to human ovarian lines A2780, A2780cisR and A2780ZD0473R. Among the phytochemicals, celastrol is most active having comparable activity against all the three ovarian tumour models. As applied to binary combinations of platinum drugs and the phytochemicals, it was found that generally synergism was greater at higher concentrations (ED75 and ED90) of drugs than at lower concentrations (ED50) in all three cell lines.

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36

Solayman, Yahya Farahat Solayman. "Combination of platinums and phytochemicals aimed to overcome drug resistance in cancer." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/23636.

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Combined chemotherapy has drawn much attention for overcoming drug resistance and improving outcomes during the treatment of advanced stages of cancer. In the present study, cisplatin, oxaliplatin, LH5, gemcitabine, camptothecin and cucurbitacin B have been combined in a binary mode using three different sequences; i.e. bolus, 0/4 h and 4/0 h, in the ovarian and colorectal cancer models. Among the tested combinations of drugs, the combination of cisplatin with camptothecin and gemcitabine at all concentrations and for all sequences of addition, proved to be beneficial in overcoming cisplatin r

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37

Picard, Gabriel. "Discovery of Novel Neurologically Active Phytochemicals in Neotropical Piperaceae: An Ethnopharmacological Approach." Thesis, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20437.

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The goal of this thesis was to understand and quantify to what extent plants are used for the treatment of mental and folk illnesses such as susto and mal aire in the Neotropics and to investigate the anxiolytic and antiepileptic potential of previously unstudied Neotropical members of the genera Piper and Peperomia. Firstly, the literature was reviewed and a regression analysis method was used in order to quantitatively determine which plant families are preferred for the treatment of mental, behavioral and neurological health disorders in the Neotropics. This analysis identified Piperaceae,

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38

Waroonphan, Saran. "Effects of Bioactive Phytochemicals on the Oxidative stability of Low Density Lipoproteins." Thesis, University of Reading, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.521030.

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39

Elgaafary, Menna [Verfasser]. "Pharmacological studies on phytochemicals for the treatment of prostate cancer / Menna Elgaafary." Ulm : Universität Ulm. Medizinische Fakultät, 2016. http://d-nb.info/1081985909/34.

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40

Gee, Jennifer Margaret. "Interactions between dietary phytochemicals and epithelial cells of the mammalian gastrointestinal tract." Thesis, University of East Anglia, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393313.

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41

Wootton-Beard, P. "Determination of phytochemicals in vegetable juices and their effects on postprandial glycaemia." Thesis, Oxford Brookes University, 2012. http://radar.brookes.ac.uk/radar/items/d45298cc-b6c9-1860-5aa7-f7eee65653ee/1.

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High fruit and vegetable intake correlates well with positive health outcomes and reduced rates of chronic diseases such as cardiovascular diseases, type 2 diabetes, cancers, neurological decline and metabolic diseases. Bioactive phytochemicals such as polyphenols, carotenoids, vitamins, minerals and others present in fruit and vegetables may be at least partly responsible for this effect. The precise mechanisms of action for several groups of compounds, and their potential impacts upon each sphere of health have not yet been fully elucidated. This work provides novel analysis of the total ant

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42

Harris, Cory S. "Anti-diabetic and neuroprotective activities of phytochemicals in traditionally used boreal plants." Thesis, University of Ottawa (Canada), 2008. http://hdl.handle.net/10393/30161.

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This thesis investigated the phytochemistry and pharmacology of boreal plant species used traditionally as treatments for symptoms and complications of diabetes and was completed in collaboration with the Team in Aboriginal Anti-Diabetic Medicine and the Cree of Eeyou Istchee in northern Quebec. Using a novel metabolomic-based approach, we first developed methods of phytochemical analysis to characterize Vaccinium angustifolium extracts and then other medicinal Ericaceae, identifying and quantifying an abundance of phenolic compounds. These methods were then employed to profile the phenolics

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43

Pal, Rituraj. "PDI, reactive oxygen species stress and polyphenolic phytochemicals implications for neurodegenerative diseases /." To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2009. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.

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Bali, Hana. "Synergism from combination of platinum drugs and selected phytochemicals in colorectal cancer." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/18798.

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Colorectal cancer is the second most leading cause of death among all reported cancer mortality. Chemotherapy is the treatment of choice to treat metastasized colorectal cancer patients. Combined administration of drugs having different mechanism of actions has been demonstrated better efficacy than conventional monotherapy. Epidemiological data suggests that consumption of phytochemicals has a great impact in prevention and treatment of colorectal cancer. In this study four phytochemicals including curcumin, colchicine, EGCG and taxol were combined with cisplatin and oxaliplatin in a binary m

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45

Lee, Tak-wing Davy. "Effect of garlic derivative s-allylcysteine (SAC) on the growth of human esophagealand nasopharyngeal carcinoma cells /." View the Table of Contents & Abstract, 2007. http://sunzi.lib.hku.hk/hkuto/record/B38296998.

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46

Chu, Qingjun, and 褚慶軍. "S-allylcysteine (SAC) and S-allylmercaptocysteine (SAMC), water soluble garlic derivatives, suppress growth and invasion of androgen-independent prostate cancer, under in vitro and in vivo conditions." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B37935653.

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47

Howard, Edward William. "The potential clinical applications of garlic-derived S-allylmercaptocysteine in the treatment of hormone refractory prostatecancer." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B38834856.

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48

Klein, Ana Paula Palaro. "Estudo fitoquímico das folhas de capim annoni-2 (Eragrostis plana Nees) coletadas no inverno e verão." Universidade Tecnológica Federal do Paraná, 2015. http://repositorio.utfpr.edu.br/jspui/handle/1/1495.

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CNPq<br>O Capim Annoni-2 (Eragrostis plana Nees) é uma poaceae que apresenta potencial alelopático conforme observado em trabalhos anteriores. Neste estudo os extratos, obtidos com solventes em ordem crescente de polaridade (éter de petróleo, acetato de etila e metanol), das folhas de Capim Annoni-2, coletadas no verão e inverno, foram analisados e comparados, levando-se em conta composição e/ou concentração de metabólitos produzidos, utilizando-se técnicas de Infravermelho e Cromatografia Líquida de Alta Eficiência, sendo que, os dados de Infravermelho foram comparados estatisticamente por PC

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49

Zhang, Qi. "The study of novel dioxin antagonist-euxanthone and its derivatives." HKBU Institutional Repository, 2003. http://repository.hkbu.edu.hk/etd_ra/507.

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50

Oh, Myungmin. "Plant adaptation and enhancement of phytochemicals in lettuce in response to environmental stresses." Diss., Manhattan, Kan. : Kansas State University, 2008. http://hdl.handle.net/2097/673.

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